ABIN967059

antibody from antibodies-online

Targeting: SNAI2 SLUG, SLUGH, SLUGH1, SNAIL2

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN967059

Provider

antibodies-online

Product name

anti-Snail Homolog 2 (Drosophila) (SNAI2) (C-Term), (pSer155), (pSer158), (pSer160), (pTyr164), (pTyr169) antibody

Antibody type

Polyclonal

Antigen

Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human SNAI2

Reactivity

Human, Mouse, Rat

Epitope

C-Term,pSer155,pSer158,pSer160,pTyr164,pTyr169

Vial size

0.1 mg

References

Submitted references

Requirement of the Akt/beta-catenin pathway for uterine carcinosarcoma genesis, modulating E-cadherin expression through the transactivation of slug.

Saegusa M, Hashimura M, Kuwata T, Okayasu I
The American journal of pathology 2009 Jun;174(6):2107-15

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p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug.

Wang SP, Wang WL, Chang YL, Wu CT, Chao YC, Kao SH, Yuan A, Lin CW, Yang SC, Chan WK, Li KC, Hong TM, Yang PC
Nature cell biology 2009 Jun;11(6):694-704

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Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer.

Larriba MJ, Martín-Villar E, García JM, Pereira F, Peña C, de Herreros AG, Bonilla F, Muñoz A
Carcinogenesis 2009 Aug;30(8):1459-68

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Human Slug is a repressor that localizes to sites of active transcription.

Hemavathy K, Guru SC, Harris J, Chen JD, Ip YT
Molecular and cellular biology 2000 Jul;20(14):5087-95

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SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein.

Inukai T, Inoue A, Kurosawa H, Goi K, Shinjyo T, Ozawa K, Mao M, Inaba T, Look AT
Molecular cell 1999 Sep;4(3):343-52