ABCA6

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24 and may play a role in macrophage lipid homeostasis. [provided by RefSeq, Jul 2008]

Description

ATP binding cassette subfamily A member 6

Tissue specificity

Tissue enhanced (liver)

Subcell location

Nucleoplasm

Predicted location

Intracellular, Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Kim et al 2014)
Transporters

Chromosome

17 (69078702 - 69141895)

Ensembl ID

ENSG00000154262  (ver. 103.38)

Orthologs

Mouse Abca6: ENSMUSG00000044749

UniProt

Q8N139

neXtProt

NX_Q8N139

Human splice variants
Mouse splice variants

Protein structure