Antibody data
- Antibody Data
- Antigen structure
- References [21]
- Comments [0]
- Validations
- Immunohistochemistry [2]
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Validation data
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- Product number
- 14075-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14075-1-AP, RRID:AB_2162208
- Product name
- PDGFD antibody
- Antibody type
- Polyclonal
- Description
- PDGFD antibody (Cat. #14075-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references PDGFD: A Dual-Function Regulator That Maintains Myoblast Pool and Fuels Myogenic Differentiation.
Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury.
Loss of TRAIP Could Attenuate the Breast Cancer Cells Development by Regulating PLSCR4 Stabilization.
The RNA-Binding Proteins MCPIP2 and IGF2BP1 Competitively Modulate Breast Tumor Angiogenesis by Antagonizing VEGFA mRNA Stability and Expression.
Identifying Potential Drug Targets for Keloid: A Mendelian Randomization Study.
The Pdgfd-Pdgfrb axis orchestrates tumor-nerve crosstalk in pancreatic cancer.
Exploring the impact of PDGFD in osteosarcoma metastasis through single-cell sequencing analysis.
Shark Cartilage-Derived Anti-Angiogenic Peptide Inhibits Corneal Neovascularization.
CCL28 promotes progression of hepatocellular carcinoma through PDGFD-regulated MMP9 and VEGFA pathways.
Cutting Edge: PDGF-DD Binding to NKp44 Costimulates TLR9 Signaling and Proinflammatory Cytokine Secretion in Human Plasmacytoid Dendritic Cells.
MicroRNA miR-145-5p Inhibits Cutaneous Wound Healing by Targeting PDGFD in Diabetic Foot Ulcer.
Photocrosslinked carboxymethylcellulose-based hydrogels: Synthesis, characterization for curcumin delivery and wound healing.
BMSC-derived Exosomes Ameliorate Peritoneal Dialysis-associated Peritoneal Fibrosis via the Mir-27a-3p/TP53 Pathway.
γ-Bungarotoxin impairs the vascular endothelial barrier function by inhibiting integrin α5.
Promoted Skin Wound Healing by Tail-Amputated Eisenia foetida Proteins via the Ras/Raf/MEK/ERK Signaling Pathway.
M2 Macrophages Promote PDGFRβ(+) Pericytes Migration After Spinal Cord Injury in Mice via PDGFB/PDGFRβ Pathway.
Suppression of PDGF induces neuronal apoptosis after neonatal cerebral hypoxia and ischemia by inhibiting P-PI3K and P-AKT signaling pathways.
Novel Serum Biomarkers Detected by Protein Array in Polycystic Ovary Syndrome with Low Progesterone Level.
Natural Killer Cells Control Tumor Growth by Sensing a Growth Factor.
Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats.
Differential gene expression and immunolocalization of platelet-derived growth factors and their receptors in caprine ovaries.
Cao H, Wang J, Wang Y, Huang J, Chen W, Tang H, Chen J, Xing B, Zeng Y
Current issues in molecular biology 2026 Mar 18;48(3)
Current issues in molecular biology 2026 Mar 18;48(3)
Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury.
Zhou P, Li L, Cao Y, Chen J, Chen C, Zhang X, Chen J, Deng Y, Lin Z, Lai Y, Wang S, Tang S, Zhang W, Sun P, Zhou J
Molecular medicine reports 2026 Jan;33(1)
Molecular medicine reports 2026 Jan;33(1)
Loss of TRAIP Could Attenuate the Breast Cancer Cells Development by Regulating PLSCR4 Stabilization.
Dong Z, Chen Q, Li F, Xie W, Ma X, Ge S, Sun M, Zhao X, Zhang Z, Zhang W, Wei D, Huang S
Journal of biochemical and molecular toxicology 2026 Apr;40(4):e70825
Journal of biochemical and molecular toxicology 2026 Apr;40(4):e70825
The RNA-Binding Proteins MCPIP2 and IGF2BP1 Competitively Modulate Breast Tumor Angiogenesis by Antagonizing VEGFA mRNA Stability and Expression.
Lu W, Li H, Liu X, Li A, Xiu R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70594
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70594
Identifying Potential Drug Targets for Keloid: A Mendelian Randomization Study.
Wang Y, Wang X, Yuan Z, Liu F, Luo X, Yang J
The Journal of investigative dermatology 2025 Jan;145(1):77-84.e6
The Journal of investigative dermatology 2025 Jan;145(1):77-84.e6
The Pdgfd-Pdgfrb axis orchestrates tumor-nerve crosstalk in pancreatic cancer.
Wang P, Lester N, Perrault E, Su J, Gong D, Shiau C, Cao J, Nguyen P, Bae JW, Olgun D, Hoffman H, Lam A, Huang-Gao J, Rahaman S, Guo J, Barth J, Caldwell N, Divakar P, Reeves J, Bahrami A, He S, Patrick M, Miller E, Ganci M, Cervantes-Jaramillo G, Hong T, Wo J, Roberts H, Weissleder R, Choi H, Fernandez-Del-Castillo C, Cormier K, Ting DT, Jacks T, Zheng L, Hemberg M, Mino-Kenudson M, Hwang WL
bioRxiv : the preprint server for biology 2025 Aug 31;
bioRxiv : the preprint server for biology 2025 Aug 31;
Exploring the impact of PDGFD in osteosarcoma metastasis through single-cell sequencing analysis.
Huang Y, Cao D, Zhang M, Yang Y, Niu G, Tang L, Shen Z, Zhang Z, Bai Y, Min D, He A
Cellular oncology (Dordrecht, Netherlands) 2024 Oct;47(5):1715-1733
Cellular oncology (Dordrecht, Netherlands) 2024 Oct;47(5):1715-1733
Shark Cartilage-Derived Anti-Angiogenic Peptide Inhibits Corneal Neovascularization.
Li Y, Chen A, Hong A, Xiong S, Chen X, Xie Q
Bioengineering (Basel, Switzerland) 2024 Jul 9;11(7)
Bioengineering (Basel, Switzerland) 2024 Jul 9;11(7)
CCL28 promotes progression of hepatocellular carcinoma through PDGFD-regulated MMP9 and VEGFA pathways.
Liu Y, Chen X, Zhang X, Guo J, Tang Y, Jin C, Wu M
Discover oncology 2024 Jul 31;15(1):324
Discover oncology 2024 Jul 31;15(1):324
Cutting Edge: PDGF-DD Binding to NKp44 Costimulates TLR9 Signaling and Proinflammatory Cytokine Secretion in Human Plasmacytoid Dendritic Cells.
Barrow AD, Cella M, Edeling MA, Khan MA, Cervantes-Barragan L, Bugatti M, Schmedt C, Vermi W, Colonna M
Journal of immunology (Baltimore, Md. : 1950) 2024 Feb 1;212(3):369-374
Journal of immunology (Baltimore, Md. : 1950) 2024 Feb 1;212(3):369-374
MicroRNA miR-145-5p Inhibits Cutaneous Wound Healing by Targeting PDGFD in Diabetic Foot Ulcer.
Wang C, Huang L, Li J, Liu D, Wu B
Biochemical genetics 2024 Aug;62(4):2437-2454
Biochemical genetics 2024 Aug;62(4):2437-2454
Photocrosslinked carboxymethylcellulose-based hydrogels: Synthesis, characterization for curcumin delivery and wound healing.
Wang J, Ma Y, Meng Q, Yang Y, Zhang R, Zhong S, Gao Y, He W, Cui X
International journal of biological macromolecules 2024 Aug;275(Pt 1):133558
International journal of biological macromolecules 2024 Aug;275(Pt 1):133558
BMSC-derived Exosomes Ameliorate Peritoneal Dialysis-associated Peritoneal Fibrosis via the Mir-27a-3p/TP53 Pathway.
Zhao JL, Zhao L, Zhan QN, Liu M, Zhang T, Chu WW
Current medical science 2024 Apr;44(2):333-345
Current medical science 2024 Apr;44(2):333-345
γ-Bungarotoxin impairs the vascular endothelial barrier function by inhibiting integrin α5.
Chen W, Yu H, Sun C, Dong M, Zhao N, Wang Y, Yu K, Zhang J, Xu N, Liu W
Toxicology letters 2023 Jul 1;383:177-191
Toxicology letters 2023 Jul 1;383:177-191
Promoted Skin Wound Healing by Tail-Amputated Eisenia foetida Proteins via the Ras/Raf/MEK/ERK Signaling Pathway.
Li T, Sun Y, Wang J, Zhang C, Sun Y
ACS omega 2023 Apr 18;8(15):13935-13943
ACS omega 2023 Apr 18;8(15):13935-13943
M2 Macrophages Promote PDGFRβ(+) Pericytes Migration After Spinal Cord Injury in Mice via PDGFB/PDGFRβ Pathway.
Li Z, Zheng M, Yu S, Yao F, Luo Y, Liu Y, Tian D, Cheng L, Jing J
Frontiers in pharmacology 2021;12:670813
Frontiers in pharmacology 2021;12:670813
Suppression of PDGF induces neuronal apoptosis after neonatal cerebral hypoxia and ischemia by inhibiting P-PI3K and P-AKT signaling pathways.
Xiong LL, Xue LL, Jiang Y, Ma Z, Jin Y, Wang YC, Wang YY, Xia QJ, Zhang Y, Hu Q, Liu J, Wang TH
Brain research 2019 Sep 15;1719:77-88
Brain research 2019 Sep 15;1719:77-88
Novel Serum Biomarkers Detected by Protein Array in Polycystic Ovary Syndrome with Low Progesterone Level.
Zheng Q, Zhou F, Cui X, Liu M, Li Y, Liu S, Tan J, Yan Q
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(6):2297-2310
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(6):2297-2310
Natural Killer Cells Control Tumor Growth by Sensing a Growth Factor.
Barrow AD, Edeling MA, Trifonov V, Luo J, Goyal P, Bohl B, Bando JK, Kim AH, Walker J, Andahazy M, Bugatti M, Melocchi L, Vermi W, Fremont DH, Cox S, Cella M, Schmedt C, Colonna M
Cell 2018 Jan 25;172(3):534-548.e19
Cell 2018 Jan 25;172(3):534-548.e19
Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats.
Dong D, Yin L, Qi Y, Xu L, Peng J
Nutrients 2015 Jun 15;7(6):4829-50
Nutrients 2015 Jun 15;7(6):4829-50
Differential gene expression and immunolocalization of platelet-derived growth factors and their receptors in caprine ovaries.
Brito IR, Sales AD, Rodrigues GQ, Lobo CH, Castro SV, Silva AW, Moura AA, Silva JR, Rodrigues AP, Figueiredo JR
Domestic animal endocrinology 2015 Apr;51:46-55
Domestic animal endocrinology 2015 Apr;51:46-55
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human prostate cancer using 14075-1-AP(PDGFD antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The PDGFD antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PDGFD. This antibody recognizes human, mouse, rat antigen. The PDGFD antibody has been validated for the following applications: ELISA, IHC analysis.