AF1159

antibody from R&D Systems

Targeting: PDGFD IEGF, MSTP036, SCDGF-B

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

AF1159

Provider

R&D Systems

Product name

Human PDGF-D Antibody

Antibody type

Polyclonal

Description

Immunogen affinity purified. Detects human PDGF-D in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) PDGF-AA, rhPDGF-AB and rhPDGF-BB is observed.

Reactivity

Human

Host

Goat

Conjugate

Unconjugated

Antigen sequence

Q9GZP0


Isotype

IgG

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

High expression of PDGFR-β in prostate cancer stroma is independently associated with clinical and biochemical prostate cancer recurrence.

Nordby Y, Richardsen E, Rakaee M, Ness N, Donnem T, Patel HR, Busund LT, Bremnes RM, Andersen S
Scientific reports 2017 Feb 24;7:43378

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Dynamic regulation of platelet-derived growth factor D (PDGF-D) activity and extracellular spatial distribution by matriptase-mediated proteolysis.

Huang W, Kim HR
The Journal of biological chemistry 2015 Apr 3;290(14):9162-70

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Effects of PDGF-C and PDGF-D on monocyte migration and MMP-2 and MMP-9 expression.

Wågsäter D, Zhu C, Björck HM, Eriksson P
Atherosclerosis 2009 Feb;202(2):415-23

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Expression of platelet-derived growth factors C and D in the synovial membrane of patients with rheumatoid arthritis and osteoarthritis.

Pohlers D, Huber R, Ukena B, Kinne RW
Arthritis and rheumatism 2006 Mar;54(3):788-94