Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 55309-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- MAT2A antibody
- Antibody type
- Polyclonal
- Description
- MAT2A antibody (Cat. #55309-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references MAT2A inhibition suppresses inflammation in Porphyromonas gingivalis-infected human gingival fibroblasts.
Antibiotic-Induced Gut Microbiota Dysbiosis Modulates Host Transcriptome and m(6)A Epitranscriptome via Bile Acid Metabolism.
Identification of a Sonically Activated Degrader of Methionine Adenosyltransferase 2A by an in Silico Approach Assisted with the Hole-Electron Analysis.
PRMT1 orchestrates with SAMTOR to govern mTORC1 methionine sensing via Arg-methylation of NPRL2.
Methionine orchestrates the metabolism vulnerability in cisplatin resistant bladder cancer microenvironment.
Oxidative Stress Aggravates Apoptosis of Nucleus Pulposus Cells through m(6)A Modification of MAT2A Pre-mRNA by METTL16.
M(6)A RNA Methylation Mediates NOD1/NF-kB Signaling Activation in the Liver of Piglets Challenged with Lipopolysaccharide.
Time-restricted feeding mitigates obesity through adipocyte thermogenesis.
Inhibition of MAT2A suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss.
mTORC1 stimulates cell growth through SAM synthesis and m(6)A mRNA-dependent control of protein synthesis.
Activating transcription factor 4 regulates angiogenesis under lipid overload via methionine adenosyltransferase 2A-mediated endothelial epigenetic alteration.
The SESAME complex regulates cell senescence through the generation of acetyl-CoA.
Ligustrazine modulates renal cysteine biosynthesis in rats exposed to cadmium.
Jiang L, Li J, Ji K, Lei L, Li H
Journal of oral microbiology 2024;16(1):2292375
Journal of oral microbiology 2024;16(1):2292375
Antibiotic-Induced Gut Microbiota Dysbiosis Modulates Host Transcriptome and m(6)A Epitranscriptome via Bile Acid Metabolism.
Yang M, Zheng X, Fan J, Cheng W, Yan TM, Lai Y, Zhang N, Lu Y, Qi J, Huo Z, Xu Z, Huang J, Jiao Y, Liu B, Pang R, Zhong X, Huang S, Luo GZ, Lee G, Jobin C, Eren AM, Chang EB, Wei H, Pan T, Wang X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jul;11(28):e2307981
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jul;11(28):e2307981
Identification of a Sonically Activated Degrader of Methionine Adenosyltransferase 2A by an in Silico Approach Assisted with the Hole-Electron Analysis.
He H, Wang Z, Peng X, Qing L, Zhang Y, Fu S, Xu J, Li Y, Zhang S
Journal of medicinal chemistry 2024 Jan 11;67(1):543-554
Journal of medicinal chemistry 2024 Jan 11;67(1):543-554
PRMT1 orchestrates with SAMTOR to govern mTORC1 methionine sensing via Arg-methylation of NPRL2.
Jiang C, Liu J, He S, Xu W, Huang R, Pan W, Li X, Dai X, Guo J, Zhang T, Inuzuka H, Wang P, Asara JM, Xiao J, Wei W
Cell metabolism 2023 Dec 5;35(12):2183-2199.e7
Cell metabolism 2023 Dec 5;35(12):2183-2199.e7
Methionine orchestrates the metabolism vulnerability in cisplatin resistant bladder cancer microenvironment.
Yang C, Ou Y, Zhou Q, Liang Y, Li W, Chen Y, Chen W, Wu S, Chen Y, Dai X, Chen X, Chen T, Jin S, Liu Y, Zhang L, Liu S, Hu Y, Zou L, Mao S, Jiang H
Cell death & disease 2023 Aug 15;14(8):525
Cell death & disease 2023 Aug 15;14(8):525
Oxidative Stress Aggravates Apoptosis of Nucleus Pulposus Cells through m(6)A Modification of MAT2A Pre-mRNA by METTL16.
Chen PB, Shi GX, Liu T, Li B, Jiang SD, Zheng XF, Jiang LS
Oxidative medicine and cellular longevity 2022;2022:4036274
Oxidative medicine and cellular longevity 2022;2022:4036274
M(6)A RNA Methylation Mediates NOD1/NF-kB Signaling Activation in the Liver of Piglets Challenged with Lipopolysaccharide.
Xu M, Zhuo R, Tao S, Liang Y, Liu C, Liu Q, Wang T, Zhong X
Antioxidants (Basel, Switzerland) 2022 Sep 30;11(10)
Antioxidants (Basel, Switzerland) 2022 Sep 30;11(10)
Time-restricted feeding mitigates obesity through adipocyte thermogenesis.
Hepler C, Weidemann BJ, Waldeck NJ, Marcheva B, Cedernaes J, Thorne AK, Kobayashi Y, Nozawa R, Newman MV, Gao P, Shao M, Ramsey KM, Gupta RK, Bass J
Science (New York, N.Y.) 2022 Oct 21;378(6617):276-284
Science (New York, N.Y.) 2022 Oct 21;378(6617):276-284
Inhibition of MAT2A suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss.
Kang H, Guo Q, Dong Y, Peng R, Song K, Wang J, Liu H, Zhu M, Zhao H, Guan H, Li F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22167
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22167
mTORC1 stimulates cell growth through SAM synthesis and m(6)A mRNA-dependent control of protein synthesis.
Villa E, Sahu U, O'Hara BP, Ali ES, Helmin KA, Asara JM, Gao P, Singer BD, Ben-Sahra I
Molecular cell 2021 May 20;81(10):2076-2093.e9
Molecular cell 2021 May 20;81(10):2076-2093.e9
Activating transcription factor 4 regulates angiogenesis under lipid overload via methionine adenosyltransferase 2A-mediated endothelial epigenetic alteration.
Chen L, Liu X, Zhou H, Li G, Huang F, Zhang J, Xia T, Lei W, Zhao J, Li C, Chen M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jun;35(6):e21612
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jun;35(6):e21612
The SESAME complex regulates cell senescence through the generation of acetyl-CoA.
Chen W, Yu X, Wu Y, Tang J, Yu Q, Lv X, Zha Z, Hu B, Li X, Chen J, Ma L, Workman JL, Li S
Nature metabolism 2021 Jul;3(7):983-1000
Nature metabolism 2021 Jul;3(7):983-1000
Ligustrazine modulates renal cysteine biosynthesis in rats exposed to cadmium.
Kuang W, Zhang X, Zhu W, Lan Z
Environmental toxicology and pharmacology 2017 Sep;54:125-132
Environmental toxicology and pharmacology 2017 Sep;54:125-132
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The MAT2A antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human MAT2A. This antibody recognizes human, mouse antigen. The MAT2A antibody has been validated for the following applications: ELISA, WB analysis.