Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- PAB12387 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB12387, RRID:AB_10554495
- Product name
- MAT2A polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of MAT2A.
- Storage
- Store at 4°C for short term. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Leptin's mitogenic effect in human liver cancer cells requires induction of both methionine adenosyltransferase 2A and 2beta.
Transcription of the MAT2A gene, coding for methionine adenosyltransferase, is up-regulated by E2F and Sp1 at a chromatin level during proliferation of liver cells.
Silencing MAT2A gene by RNA interference inhibited cell growth and induced apoptosis in human hepatoma cells.
Ramani K, Yang H, Xia M, Ara AI, Mato JM, Lu SC
Hepatology (Baltimore, Md.) 2008 Feb;47(2):521-31
Hepatology (Baltimore, Md.) 2008 Feb;47(2):521-31
Transcription of the MAT2A gene, coding for methionine adenosyltransferase, is up-regulated by E2F and Sp1 at a chromatin level during proliferation of liver cells.
Rodríguez JL, Boukaba A, Sandoval J, Georgieva EI, Latasa MU, García-Trevijano ER, Serviddio G, Nakamura T, Avila MA, Sastre J, Torres L, Mato JM, López-Rodas G
The international journal of biochemistry & cell biology 2007;39(4):842-50
The international journal of biochemistry & cell biology 2007;39(4):842-50
Silencing MAT2A gene by RNA interference inhibited cell growth and induced apoptosis in human hepatoma cells.
Liu Q, Wu K, Zhu Y, He Y, Wu J, Liu Z
Hepatology research : the official journal of the Japan Society of Hepatology 2007 May;37(5):376-88
Hepatology research : the official journal of the Japan Society of Hepatology 2007 May;37(5):376-88
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Supportive validation
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- Abnova Corporation (provider)
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- Experimental details
- Western blot analysis of MAT2A in HepG2 whole cell lysates using MAT2A polyclonal antibody (Cat # PAB12387).