Antibody data
- Antibody Data
- Antigen structure
- References [17]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
Reference
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- Product number
- 21277-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21277-1-AP, RRID:AB_10858921
- Product name
- SR-BI antibody
- Antibody type
- Polyclonal
- Description
- SR-BI antibody (Cat. #21277-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Flagellar hook protein FlgE promotes macrophage activation and atherosclerosis by targeting ATP5B.
Quinic acid regulated TMA/TMAO-related lipid metabolism and vascular endothelial function through gut microbiota to inhibit atherosclerotic.
Inflammatory Cell-Derived MYDGF Attenuates Endothelial LDL Transcytosis to Protect Against Atherogenesis.
Resveratrol attenuates efavirenz-induced hepatic steatosis and hypercholesterolemia in mice by inhibiting pregnane X receptor activation and decreasing inflammation.
The NR_109/FUBP1/c-Myc axis regulates TAM polarization and remodels the tumor microenvironment to promote cancer development.
Engineered Microparticles for Treatment of Murine Brain Metastasis by Reprograming Tumor Microenvironment and Inhibiting MAPK Pathway.
L-Theanine regulates lipid metabolism by modulating gut microbiota and bile acid metabolism.
Urolithin A protects severe acute pancreatitis-associated acute cardiac injury by regulating mitochondrial fatty acid oxidative metabolism in cardiomyocytes.
Inclisiran inhibits oxidized low-density lipoprotein-induced foam cell formation in Raw264.7 macrophages via activating the PPARγ pathway.
Effects of Bushen Yiyuan recipe on testosterone synthesis in Leydig cells of rats with exercise-induced low serum testosterone levels.
Opuntia dillenii Haw. Polysaccharide Promotes Cholesterol Efflux in THP-1-Derived Foam Cells via the PPARγ-LXRα Signaling Pathway.
Photobiomodulation therapy promotes the ATP-binding cassette transporter A1-dependent cholesterol efflux in macrophage to ameliorate atherosclerosis.
Targeted immunomodulation of inflammatory monocytes across the blood-brain barrier by curcumin-loaded nanoparticles delays the progression of experimental autoimmune encephalomyelitis.
Effects of sepsis on the metabolism of sphingomyelin and cholesterol in mice with liver dysfunction.
Neglected but Important Role of Apolipoprotein E Exchange in Hepatitis C Virus Infection.
TSH increases synthesis of hepatic ATP-binding cassette subfamily A member 1 in hypercholesterolemia.
ApoA-I induces S1P release from endothelial cells through ABCA1 and SR-BI in a positive feedback manner.
Li Y, Zhang M, Li Y, Shen Y, Wang X, Li X, Wang Y, Yu T, Lv J, Qin Y
Atherosclerosis 2024 Mar;390:117429
Atherosclerosis 2024 Mar;390:117429
Quinic acid regulated TMA/TMAO-related lipid metabolism and vascular endothelial function through gut microbiota to inhibit atherosclerotic.
Jin Q, Zhang C, Chen R, Jiang L, Li H, Wu P, Li L
Journal of translational medicine 2024 Apr 15;22(1):352
Journal of translational medicine 2024 Apr 15;22(1):352
Inflammatory Cell-Derived MYDGF Attenuates Endothelial LDL Transcytosis to Protect Against Atherogenesis.
Xu J, Ma H, Shi L, Zhou H, Cheng Y, Tong J, Meng B, Xu X, He K, Ding S, Zhang J, Yue L, Xiang G
Arteriosclerosis, thrombosis, and vascular biology 2023 Nov;43(11):e443-e467
Arteriosclerosis, thrombosis, and vascular biology 2023 Nov;43(11):e443-e467
Resveratrol attenuates efavirenz-induced hepatic steatosis and hypercholesterolemia in mice by inhibiting pregnane X receptor activation and decreasing inflammation.
Miao X, Ye H, Cui X, Guo X, Su F
Nutrition research (New York, N.Y.) 2023 Nov;119:119-131
Nutrition research (New York, N.Y.) 2023 Nov;119:119-131
The NR_109/FUBP1/c-Myc axis regulates TAM polarization and remodels the tumor microenvironment to promote cancer development.
Zhang C, Wei S, Dai S, Li X, Wang H, Zhang H, Sun G, Shan B, Zhao L
Journal for immunotherapy of cancer 2023 May;11(5)
Journal for immunotherapy of cancer 2023 May;11(5)
Engineered Microparticles for Treatment of Murine Brain Metastasis by Reprograming Tumor Microenvironment and Inhibiting MAPK Pathway.
Lu L, Zi H, Zhou J, Huang J, Deng Z, Tang Z, Li L, Shi X, Lo PC, Lovell JF, Deng D, Wan C, Jin H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Mar;10(8):e2206212
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Mar;10(8):e2206212
L-Theanine regulates lipid metabolism by modulating gut microbiota and bile acid metabolism.
Xu W, Kong Y, Zhang T, Gong Z, Xiao W
Journal of the science of food and agriculture 2023 Feb;103(3):1283-1293
Journal of the science of food and agriculture 2023 Feb;103(3):1283-1293
Urolithin A protects severe acute pancreatitis-associated acute cardiac injury by regulating mitochondrial fatty acid oxidative metabolism in cardiomyocytes.
Yang Y, Hu Q, Kang H, Li J, Zhao X, Zhu L, Tang W, Wan M
MedComm 2023 Dec;4(6):e459
MedComm 2023 Dec;4(6):e459
Inclisiran inhibits oxidized low-density lipoprotein-induced foam cell formation in Raw264.7 macrophages via activating the PPARγ pathway.
Wang Z, Chen X, Liu J, Wang Y, Zhang S
Autoimmunity 2022 Jun;55(4):223-232
Autoimmunity 2022 Jun;55(4):223-232
Effects of Bushen Yiyuan recipe on testosterone synthesis in Leydig cells of rats with exercise-induced low serum testosterone levels.
Wang Y, Peng X, Zhou Z, Tang C, Liu W
Pharmaceutical biology 2022 Dec;60(1):1670-1678
Pharmaceutical biology 2022 Dec;60(1):1670-1678
Opuntia dillenii Haw. Polysaccharide Promotes Cholesterol Efflux in THP-1-Derived Foam Cells via the PPARγ-LXRα Signaling Pathway.
Li H, Huang Z, Zeng F
Molecules (Basel, Switzerland) 2022 Dec 7;27(24)
Molecules (Basel, Switzerland) 2022 Dec 7;27(24)
Photobiomodulation therapy promotes the ATP-binding cassette transporter A1-dependent cholesterol efflux in macrophage to ameliorate atherosclerosis.
Yin Q, Chang H, Shen Q, Xing D
Journal of cellular and molecular medicine 2021 Jun;25(11):5238-5249
Journal of cellular and molecular medicine 2021 Jun;25(11):5238-5249
Targeted immunomodulation of inflammatory monocytes across the blood-brain barrier by curcumin-loaded nanoparticles delays the progression of experimental autoimmune encephalomyelitis.
Lu L, Qi S, Chen Y, Luo H, Huang S, Yu X, Luo Q, Zhang Z
Biomaterials 2020 Jul;245:119987
Biomaterials 2020 Jul;245:119987
Effects of sepsis on the metabolism of sphingomyelin and cholesterol in mice with liver dysfunction.
Li J, Xia K, Xiong M, Wang X, Yan N
Experimental and therapeutic medicine 2017 Dec;14(6):5635-5640
Experimental and therapeutic medicine 2017 Dec;14(6):5635-5640
Neglected but Important Role of Apolipoprotein E Exchange in Hepatitis C Virus Infection.
Yang Z, Wang X, Chi X, Zhao F, Guo J, Ma P, Zhong J, Niu J, Pan X, Long G
Journal of virology 2016 Nov 1;90(21):9632-9643
Journal of virology 2016 Nov 1;90(21):9632-9643
TSH increases synthesis of hepatic ATP-binding cassette subfamily A member 1 in hypercholesterolemia.
Zhang T, Zhou L, Li CC, Shi H, Zhou X
Biochemical and biophysical research communications 2016 Jul 22;476(2):75-81
Biochemical and biophysical research communications 2016 Jul 22;476(2):75-81
ApoA-I induces S1P release from endothelial cells through ABCA1 and SR-BI in a positive feedback manner.
Liu X, Ren K, Suo R, Xiong SL, Zhang QH, Mo ZC, Tang ZL, Jiang Y, Peng XS, Yi GH
Journal of physiology and biochemistry 2016 Dec;72(4):657-667
Journal of physiology and biochemistry 2016 Dec;72(4):657-667
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 21277-1-AP(SCARB1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using SCARB1 antibody 21277-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line