Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 21686-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21686-1-AP, RRID:AB_10792410
- Product name
- NF2 antibody
- Antibody type
- Polyclonal
- Description
- NF2 antibody (Cat. #21686-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Inhibition of DNA Methyltransferase 1 Ameliorates Renal Injuries in Diabetic Nephropathy by Targeting NF2.
De novo pyrimidine synthesis is a collateral metabolic vulnerability in NF2-deficient mesothelioma.
DDR1 Targeting HOXA6 Facilitates Bladder Cancer Progression via Inhibiting Ferroptosis.
Taurine Attenuates Neuronal Ferroptosis by CSF-Derived Exosomes of GABABR Encephalitis Through GABABR/NF2/P-YAP Pathway.
Phosphoproteome Reveals the Role of Baicalin in Alleviating rPVL-Induced Cell Cycle Arrest in BMECs.
Eosinophilic Solid and Cystic Renal Cell Carcinoma: Morphologic and Immunohistochemical Study of 18 Cases and Review of the Literature.
PXD101 inhibits malignant progression and radioresistance of glioblastoma by upregulating GADD45A.
The Hippo pathway terminal effector TAZ/WWTR1 mediates oxaliplatin sensitivity in p53 proficient colon cancer cells.
PWP1 Promotes the Malignant Phenotypes of Lung Cancer Cells by Interacting with DVL2 and Merlin.
MiR-25-3p Serves as an Oncogenic MicroRNA by Downregulating the Expression of Merlin in Osteosarcoma.
Metformin suppresses proliferation and invasion of drug-resistant breast cancer cells by activation of the Hippo pathway.
Enhancement of tenogenic differentiation of rat tendon-derived stem cells by biglycan.
MicroRNA-146b-3p Promotes Cell Metastasis by Directly Targeting NF2 in Human Papillary Thyroid Cancer.
A hairpin within YAP mRNA 3'UTR functions in regulation at post-transcription level.
Zhang X, Song Y, Huang X, Wang X, Yuan W, Zhu N
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 15;40(5):e71624
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 15;40(5):e71624
De novo pyrimidine synthesis is a collateral metabolic vulnerability in NF2-deficient mesothelioma.
Xu D, Gao Y, Liu S, Yin S, Hu T, Deng H, Zhang T, Hegedüs B, Marti TM, Dorn P, Liang SQ, Schmid RA, Peng RW, Shu Y
EMBO molecular medicine 2025 Sep;17(9):2258-2298
EMBO molecular medicine 2025 Sep;17(9):2258-2298
DDR1 Targeting HOXA6 Facilitates Bladder Cancer Progression via Inhibiting Ferroptosis.
Xie X, He H, Zhang N, Wang X, Rui W, Xu D, Zhu Y, Tian M, He W
Journal of cellular and molecular medicine 2025 Mar;29(6):e70410
Journal of cellular and molecular medicine 2025 Mar;29(6):e70410
Taurine Attenuates Neuronal Ferroptosis by CSF-Derived Exosomes of GABABR Encephalitis Through GABABR/NF2/P-YAP Pathway.
Zhang C, Zhou T, Qiao S, Lu L, Zhu M, Wang A, Zhang S
Molecular neurobiology 2025 Jul;62(7):9052-9073
Molecular neurobiology 2025 Jul;62(7):9052-9073
Phosphoproteome Reveals the Role of Baicalin in Alleviating rPVL-Induced Cell Cycle Arrest in BMECs.
Hou L, Li J, Wang J, You Q, Zhang D, Zhou X
Microorganisms 2025 Jul 16;13(7)
Microorganisms 2025 Jul 16;13(7)
Eosinophilic Solid and Cystic Renal Cell Carcinoma: Morphologic and Immunohistochemical Study of 18 Cases and Review of the Literature.
Guo Q, Yao X, Yang B, Qi L, Wang F, Guo Y, Liu Y, Cao Z, Wang Y, Wang J, Li L, Huang Q, Liu C, Qu T, Zhao W, Ren D, Yang M, Yan C, Meng B, Wang C, Cao W
Archives of pathology & laboratory medicine 2024 Oct 1;148(10):1126-1134
Archives of pathology & laboratory medicine 2024 Oct 1;148(10):1126-1134
PXD101 inhibits malignant progression and radioresistance of glioblastoma by upregulating GADD45A.
Hu X, Zhou P, Peng X, Ouyang Y, Li D, Wu X, Yang L
Journal of translational medicine 2024 Nov 20;22(1):1047
Journal of translational medicine 2024 Nov 20;22(1):1047
The Hippo pathway terminal effector TAZ/WWTR1 mediates oxaliplatin sensitivity in p53 proficient colon cancer cells.
Slaninová V, Heron-Milhavet L, Robin M, Jeanson L, Aissanou A, Kantar D, Tosi D, Bréhélin L, Gongora C, Djiane A
BMC cancer 2024 May 14;24(1):587
BMC cancer 2024 May 14;24(1):587
PWP1 Promotes the Malignant Phenotypes of Lung Cancer Cells by Interacting with DVL2 and Merlin.
Wei L, Li P, Luo Y, Zhang M, Yan T, Yang Y, Han Y, Liu S, Wang E
OncoTargets and therapy 2020;13:10025-10037
OncoTargets and therapy 2020;13:10025-10037
MiR-25-3p Serves as an Oncogenic MicroRNA by Downregulating the Expression of Merlin in Osteosarcoma.
Rao HC, Wu ZK, Wei SD, Jiang Y, Guo QX, Wang JW, Chen CX, Yang HY
Cancer management and research 2020;12:8989-9001
Cancer management and research 2020;12:8989-9001
Metformin suppresses proliferation and invasion of drug-resistant breast cancer cells by activation of the Hippo pathway.
Liu J, Li J, Chen H, Wang R, Li P, Miao Y, Liu P
Journal of cellular and molecular medicine 2020 May;24(10):5786-5796
Journal of cellular and molecular medicine 2020 May;24(10):5786-5796
Enhancement of tenogenic differentiation of rat tendon-derived stem cells by biglycan.
Zhang YJ, Qing Q, Zhang YJ, Ning LJ, Cui J, Yao X, Luo JC, Ding W, Qin TW
Journal of cellular physiology 2019 Sep;234(9):15898-15910
Journal of cellular physiology 2019 Sep;234(9):15898-15910
MicroRNA-146b-3p Promotes Cell Metastasis by Directly Targeting NF2 in Human Papillary Thyroid Cancer.
Yu C, Zhang L, Luo D, Yan F, Liu J, Shao S, Zhao L, Jin T, Zhao J, Gao L
Thyroid : official journal of the American Thyroid Association 2018 Dec;28(12):1627-1641
Thyroid : official journal of the American Thyroid Association 2018 Dec;28(12):1627-1641
A hairpin within YAP mRNA 3'UTR functions in regulation at post-transcription level.
Gao Y, Wang Y, Feng J, Feng G, Zheng M, Yang Z, Xiao Z, Lu Z, Ye L, Zhang X
Biochemical and biophysical research communications 2015 Apr 3;459(2):306-312
Biochemical and biophysical research communications 2015 Apr 3;459(2):306-312
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The NF2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human NF2. This antibody recognizes human, mouse, rat antigen. The NF2 antibody has been validated for the following applications: ELISA, WB analysis.