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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Product number
- ABIN362335 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Neurofibromin 2 (NF2) (pSer518) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pSer518 (R-L-S (p) -M-E) derived from Human Merlin. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pSer518
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Phosphorylation of ezrin by cyclin-dependent kinase 5 induces the release of Rho GDP dissociation inhibitor to inhibit Rac1 activity in senescent cells.
The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression.
Cystic fibrosis pathogens activate Ca2+-dependent mitogen-activated protein kinase signaling pathways in airway epithelial cells.
Signaling steps involving the cytoplasmic domain of the interferon-gamma receptor alpha-subunit are not species-specific.
Yang HS, Hinds PW
Cancer research 2006 Mar 1;66(5):2708-15
Cancer research 2006 Mar 1;66(5):2708-15
The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression.
Xiao GH, Gallagher R, Shetler J, Skele K, Altomare DA, Pestell RG, Jhanwar S, Testa JR
Molecular and cellular biology 2005 Mar;25(6):2384-94
Molecular and cellular biology 2005 Mar;25(6):2384-94
Cystic fibrosis pathogens activate Ca2+-dependent mitogen-activated protein kinase signaling pathways in airway epithelial cells.
Ratner AJ, Bryan R, Weber A, Nguyen S, Barnes D, Pitt A, Gelber S, Cheung A, Prince A
The Journal of biological chemistry 2001 Jun 1;276(22):19267-75
The Journal of biological chemistry 2001 Jun 1;276(22):19267-75
Signaling steps involving the cytoplasmic domain of the interferon-gamma receptor alpha-subunit are not species-specific.
Böhni R, Hemmi S, Aguet M
The Journal of biological chemistry 1994 May 20;269(20):14541-5
The Journal of biological chemistry 1994 May 20;269(20):14541-5
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