ABIN362948

antibody from antibodies-online

Targeting: NF2 ACN, BANF, merlin, SCH

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN362948

Provider

antibodies-online

Product name

anti-Neurofibromin 2 (NF2) (AA 516-520) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around AA 516-520 (R-L-S-M-E) derived from Human Merlin. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

AA 516-520

Isotype

IgG

Vial size

100 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Phosphorylation of ezrin by cyclin-dependent kinase 5 induces the release of Rho GDP dissociation inhibitor to inhibit Rac1 activity in senescent cells.

Yang HS, Hinds PW
Cancer research 2006 Mar 1;66(5):2708-15

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The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression.

Xiao GH, Gallagher R, Shetler J, Skele K, Altomare DA, Pestell RG, Jhanwar S, Testa JR
Molecular and cellular biology 2005 Mar;25(6):2384-94

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Cystic fibrosis pathogens activate Ca2+-dependent mitogen-activated protein kinase signaling pathways in airway epithelial cells.

Ratner AJ, Bryan R, Weber A, Nguyen S, Barnes D, Pitt A, Gelber S, Cheung A, Prince A
The Journal of biological chemistry 2001 Jun 1;276(22):19267-75

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Signaling steps involving the cytoplasmic domain of the interferon-gamma receptor alpha-subunit are not species-specific.

Böhni R, Hemmi S, Aguet M
The Journal of biological chemistry 1994 May 20;269(20):14541-5