Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- ABIN453191 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Neurofibromin 2 (NF2) (N-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- KLH conjugated synthetic peptide selected from the N-terminal region of human Merlin
- Description
- Saturated Ammonium Sulfate (SAS) precipitation
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- N-Term
- Vial size
- 0.4 mL
- Concentration
- 0.25 mg/mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references NF2/merlin is a novel negative regulator of mTOR complex 1, and activation of mTORC1 is associated with meningioma and schwannoma growth.
James MF, Han S, Polizzano C, Plotkin SR, Manning BD, Stemmer-Rachamimov AO, Gusella JF, Ramesh V
Molecular and cellular biology 2009 Aug;29(15):4250-61
Molecular and cellular biology 2009 Aug;29(15):4250-61
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of Merlin Antibody (N-term) (AP17560PU-N) in NCI-H460 cell line lysates (35ug/lane). NF2 (arrow) was detected using the purified Pab.