PA5-82060

antibody from Invitrogen Antibodies

Targeting: NF2 ACN, BANF, merlin, SCH

Western blot (Recommended by provider)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PA5-82060

Provider

Invitrogen Antibodies

Product name

NF2 Polyclonal Antibody

Antibody type

Polyclonal

Antigen

Recombinant protein fragment

Description

Immunogen sequence: ERRAKQKLLE IATKPTYPPM NPIPAPLPPD IPSFNLIGDS LSFDFKDTDM KRLSMEIEKE KVEYMEKSKH LQEQLNELKT EIEALKLKER ETALDILHNE NSDRGGSSKH NTIKKLTLQS AKSRVA

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

100 μL

Concentration

0.4 mg/mL

Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

References

Submitted references

Schwannoma development is mediated by Hippo pathway dysregulation and modified by RAS/MAPK signaling.

Chen Z, Li S, Mo J, Hawley E, Wang Y, He Y, Brosseau JP, Shipman T, Clapp DW, Carroll TJ, Le LQ
JCI insight 2020 Oct 15;5(20)

Immunocytochemistry

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunofluorescent analysis of NF2 in U-251 MG cells using a NF2 polyclonal antibody (Product # PA5-82060). The analysis shows localization to plasma membrane & cytosol.

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunofluorecent analysis of NF2 in human cell line U-251 MG using NF2 Polyclonal Antibody (Product # PA5-82060). Staining shows localization to plasma membrane and cytosol.

Immunohistochemistry

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemical analysis of NF2 in human testis using NF2 Polyclonal Antibody (Product # PA5-82060) shows moderate cytoplasmic positivity in cells in seminiferous ducts.

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemical analysis of NF2 in human cerebellum using NF2 Polyclonal Antibody (Product # PA5-82060) shows moderate cytoplasmic positivity in Purkinje cells.

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemical analysis of NF2 in human cerebral cortex using NF2 Polyclonal Antibody (Product # PA5-82060) shows strong cytoplasmic positivity in neurons.

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemical analysis of NF2 in human fallopian tube using NF2 Polyclonal Antibody (Product # PA5-82060) shows moderate cytoplasmic and moderate membranous positivity in glandular cells.

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemical analysis of NF2 in human testis using NF2 Polyclonal Antibody (Product # PA5-82060) shows moderate cytoplasmic positivity in cells in seminiferous ducts.

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemical analysis of NF2 in human cerebellum using NF2 Polyclonal Antibody (Product # PA5-82060) shows moderate cytoplasmic positivity in Purkinje cells.

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemical analysis of NF2 in human cerebral cortex using NF2 Polyclonal Antibody (Product # PA5-82060) shows strong cytoplasmic positivity in neurons.