Ab117821

antibody from Aladdin Scientific Corporation

Targeting: NF2 ACN, BANF, merlin, SCH

Western blot (Data presented on provider website)

Antibody Data

Product number

Ab117821

Provider

Aladdin Scientific Corporation

Product name

Recombinant NF2/Merlin Antibody

Antibody type

Recombinant

Description

Rabbit anti Human NF2/Merlin Antibody, Recombinant (R07-1A6), could be used for WB and so on.Application:WB: 1/500-1/1000Protein FunctionProbable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

AA 582-595


Antibody clone number

R07-1A6

Vial size

100μl,10μl,1ml,50μl

Concentration

1 mg/ml

Storage

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.