Ab117821

antibody from Aladdin Scientific

Targeting: NF2 ACN, BANF, merlin, SCH

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Validation data

Product number: Ab117821 - Provider product page
Provider: Aladdin Scientific
Product name: Recombinant NF2/Merlin Antibody
Antibody type: Recombinant
Description: Rabbit anti Human NF2/Merlin Antibody, Recombinant, could be used for WB and so on.Application:WB: 1/500-1/1000Protein FunctionProbable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: AA 582-595
Vial size: 100_l,10_l,1ml,50_l
Concentration: 1 mg/ml
Storage: Store at 4¡C short term (1-2 weeks). Store at -20¡C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

NF2 protein structure - Ab117821 shown in red.