15348-1-AP

antibody from Proteintech Group

Targeting: PA2G4

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

15348-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#15348-1-AP, RRID:AB_2156602

Product name

PA2G4 antibody

Antibody type

Polyclonal

Description

KD/KO validated PA2G4 antibody (Cat. #15348-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

PA2G4 in CAFs promotes biochemical recurrence of prostate cancer via H3K18la.

Ji S, Xi Z, Li T, Jia G, Zhang Y, Zheng C, Wang W, Ni W, Zhang Y, Zhou Z, Wu W, Jiang Q
Cell & bioscience 2025 Nov 4;15(1):152

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The highly conserved PIWI-interacting RNA CRAPIR antagonizes PA2G4-mediated NF110-NF45 disassembly to promote heart regeneration in mice.

Ma W, Chen H, Tian Y, Huang W, Ren Z, Li J, Ouyang Q, Hu Y, Wang X, Ji H, Liu X, Liu Y, Wang X, Liu Y, Tian Y, Li F, Yang B, Wang N, Cai B
Nature cardiovascular research 2025 Jan;4(1):102-118

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Orthogonal proteogenomic analysis identifies the druggable PA2G4-MYC axis in 3q26 AML.

Marchesini M, Gherli A, Simoncini E, Tor LMD, Montanaro A, Thongon N, Vento F, Liverani C, Cerretani E, D'Antuono A, Pagliaro L, Zamponi R, Spadazzi C, Follini E, Cambò B, Giaimo M, Falco A, Sammarelli G, Todaro G, Bonomini S, Adami V, Piazza S, Corbo C, Lorusso B, Mezzasoma F, Lagrasta CAM, Martelli MP, La Starza R, Cuneo A, Aversa F, Mecucci C, Quaini F, Colla S, Roti G
Nature communications 2024 Jun 4;15(1):4739

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Primate-Specific DAZ Regulates Translation of Cell Proliferation-Related mRNAs and is Essential for Maintenance of Spermatogonia.

Ou N, Wang Y, Xu S, Luo J, Zhang C, Zhang Y, Shi X, Xiong M, Zhao L, Ji Z, Zhang Y, Zhao J, Bai H, Tian R, Li P, Zhi E, Huang Y, Chen W, Wang R, Jin Y, Wang D, Li Z, Chen H, Yao C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(29):e2400692

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Selective ribosome profiling as a tool to study interactions of translating ribosomes in mammalian cells.

Günnigmann M, Koubek J, Kramer G, Bukau B
Methods in enzymology 2023;684:1-38

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Proliferation-associated 2G4 P48 is stabilized by malignant T-cell amplified sequence 1 and promotes the proliferation of head and neck squamous cell carcinoma.

Sun L, Xing G, Wang W, Ma X, Bu X
Journal of dental sciences 2023 Oct;18(4):1588-1597

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Evidence for a fragile X messenger ribonucleoprotein 1 (FMR1) mRNA gain-of-function toxicity mechanism contributing to the pathogenesis of fragile X-associated premature ovarian insufficiency.

Rosario R, Stewart HL, Choudhury NR, Michlewski G, Charlet-Berguerand N, Anderson RA
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22612

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PA2G4 promotes the metastasis of hepatocellular carcinoma by stabilizing FYN mRNA in a YTHDF2-dependent manner.

Sun S, Liu Y, Zhou M, Wen J, Xue L, Han S, Liang J, Wang Y, Wei Y, Yu J, Long X, Chen X, Liang H, Huang Z, Zhang B
Cell & bioscience 2022 May 7;12(1):55

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Increased PA2G4 Expression Is an Unfavorable Factor in Nasopharyngeal Carcinoma.

Xu Y, Cai H, Tu W, Ding L, Luo R
Applied immunohistochemistry & molecular morphology : AIMM 2021 Aug 1;29(7):513-518

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Jurkat cells were subjected to SDS PAGE followed by western blot with 15348-1-AP(PA2G4 antibody) at dilution of 1:2000

Sample type

cell line

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of MCF-7 cells, using PA2G4 antibody 15348-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

Sample type

cell line

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human breast cancer using 15348-1-AP(PA2G4 antibody) at dilution of 1:100 (under 10x lens)

Sample type

tissue

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human breast cancer using 15348-1-AP(PA2G4 antibody) at dilution of 1:100 (under 40x lens)

Sample type

tissue