26087-1-AP

antibody from Proteintech Group

Targeting: UFL1 KIAA0776, Maxer, NLBP, RCAD

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

26087-1-AP

Provider

Proteintech Group

Product name

UFL1 antibody

Antibody type

Polyclonal

Description

KD/KO validated UFL1 antibody (Cat. #26087-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: WB,ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

The coordinated action of UFMylation and the RQC pathways clears arrested polypeptides at the ER.

Mihailovic M, Anisimova AS, Erte B, Zhan N, Styliara I, Dagdas Y, Karagöz GE
The EMBO journal 2026 May;45(9):3252-3275

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DysUFMylation reprograms immunosuppressive neutrophils to potentiate anti-PD-1 therapy in hepatocellular carcinoma.

Gao X, Xu M, Han Z, Hu Z, Su Y, Sun G, Chen W, Qiu S, Qiu S, Hung MC, Zhou C, Yi Y
Cancer letters 2026 May 1;645:218395

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DysUFMylation of SREBP1 Promotes the Progression of Hepatocellular Carcinoma by Reprogramming Lipid Metabolism.

Gao X, Han Z, Xu M, Wang Z, Sun G, Xiao H, Zhang D, Qiu S, Ren N, Zhou C, Yi Y
Journal of clinical and translational hepatology 2025 Nov 28;13(11):949-963

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Proximity biotinylation at the host-Shigella interface reveals UFMylation as an antibacterial pathway.

López-Jiménez AT, Théry F, Wright K, Painter H, Hoffmeister ST, Jarche L, Benjamin J, van der Heden van Noort GJ, Brokatzky D, Gomes MC, Miles SL, Lobato-Márquez D, Rohde J, Pruneda JN, Impens F, Mostowy S
bioRxiv : the preprint server for biology 2025 May 29;

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Panaxatriol exerts anti-senescence effects and alleviates osteoarthritis and cartilage repair fibrosis by targeting UFL1.

Kuang B, Geng N, Yi M, Zeng Q, Fan M, Xian M, Deng L, Chen C, Pan Y, Kuang L, Luo F, Xie Y, Liu C, Deng Z, Nie M, Du Y, Guo F
Journal of advanced research 2025 Aug;74:493-511

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UFL1 regulates cellular homeostasis by targeting endoplasmic reticulum and mitochondria in NEFA-stimulated bovine mammary epithelial cells via the IRE1α/XBP1 pathway.

Yan Y, Huang J, Chen X, Li Y, Zhao W, Li C
Free radical biology & medicine 2024 Sep;222:16-26

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CDK5RAP3 is a novel super-enhancer-driven gene activated by master TFs and regulates ER-Phagy in neuroblastoma.

Zhuo R, Zhang Z, Chen Y, Li G, Du S, Guo X, Yang R, Tao Y, Li X, Fang F, Xie Y, Wu D, Yang Y, Yang C, Yin H, Qian G, Wang H, Yu J, Jia S, Zhu F, Feng C, Wang J, Xu Y, Li Z, Shi L, Wang X, Pan J, Wang J
Cancer letters 2024 Jun 1;591:216882

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Screening UFMylation-associated genes in heart tissues of Ufm1-transgenic mice.

Jiajia H, Ziyao Y, Jiaqi Z, Yanli C, Xiaotao Z, Ming S
BMC cardiovascular disorders 2023 Nov 18;23(1):567

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An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation.

Yiu SPT, Zerbe C, Vanderwall D, Huttlin EL, Weekes MP, Gewurz BE
Molecular cell 2023 Jul 6;83(13):2367-2386.e15

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UFL1 regulates milk protein and fat synthesis-related gene expression of bovine mammary epithelial cells probably via the mTOR signaling pathway.

Li C, Li L, Ali I, Kuang M, Wang X, Wang G
In vitro cellular & developmental biology. Animal 2021 May;57(5):550-559

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UFM1-Specific Ligase 1 Ligating Enzyme 1 Mediates Milk Protein and Fat Synthesis-Related Gene Expression via the JNK Signaling Pathway in Mouse Mammary Epithelial Cells.

Kuang M, Yang M, Li L, Li C, Wang G
Oxidative medicine and cellular longevity 2020;2020:4045674

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UFL1 Alleviates LPS-Induced Apoptosis by Regulating the NF-κB Signaling Pathway in Bovine Ovarian Granulosa Cells.

Wang X, Li C, Wang Y, Li L, Han Z, Wang G
Biomolecules 2020 Feb 9;10(2)

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UFL1 Alleviates Lipopolysaccharide-Induced Cell Damage and Inflammation via Regulation of the TLR4/NF-κB Pathway in Bovine Mammary Epithelial Cells.

Li C, Li L, Chen K, Wang Y, Yang F, Wang G
Oxidative medicine and cellular longevity 2019;2019:6505373

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Protective effects of UFL1 against endoplasmic reticulum stress-induced autophagy in bovine mammary epithelial cells.

Kuang M, Li L, Li C, Wang G
Cell stress & chaperones 2019 Nov;24(6):1115-1125

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UFL1 modulates NLRP3 inflammasome activation and protects against pyroptosis in LPS-stimulated bovine mammary epithelial cells.

Li C, Wang X, Kuang M, Li L, Wang Y, Yang F, Wang G
Molecular immunology 2019 Aug;112:1-9