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- References [14]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 15544-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15544-1-AP, RRID:AB_2257220
- Product name
- WDR5 antibody
- Antibody type
- Polyclonal
- Description
- WDR5 antibody (Cat. #15544-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references METTL3-mediated m6A modification of TIFA mRNA promotes tubular cell pyroptosis in acute kidney injury.
TBX21 knockdown attenuates neuroinflammation induced by intracerebral hemorrhage via the SIRT1-WDR5-H3K4me3 axis.
NEAT1 promotes the perineural invasion of pancreatic cancer via the E2F1/GDNF axis.
The m6A hypermethylation-induced PIR overexpression regulates H3K4me3 and promotes tumorigenesis of uveal melanoma.
Targeting pancreatic cancer glutamine dependency confers vulnerability to GPX4-dependent ferroptosis.
EIF3D safeguards the homeostasis of key signaling pathways in human primed pluripotency.
Effect of subcutaneous adipose tissue-associated CSRP2 on the progression of prostate cancer via the WDR5/USP44 pathway.
Glucagon-like peptide-1 receptor agonist exendin 4 ameliorates diabetes-associated vascular calcification by regulating mitophagy through the AMPK signaling pathway.
Transcriptional and epigenetic dysregulation impairs generation of proliferative neural stem and progenitor cells during brain aging.
USP36 regulates the proliferation, survival, and differentiation of hFOB1.19 osteoblast.
HPV E7-drived ALKBH5 promotes cervical cancer progression by modulating m6A modification of PAK5.
KMT2A associates with PHF5A-PHF14-HMG20A-RAI1 subcomplex in pancreatic cancer stem cells and epigenetically regulates their characteristics.
A MYC inhibitor selectively alters the MYC and MAX cistromes and modulates the epigenomic landscape to regulate target gene expression.
Compensatory functions of histone deacetylase 1 (HDAC1) and HDAC2 regulate transcription and apoptosis during mouse oocyte development.
Ji ML, Peng LJ, Zhu Q, Cheng XR, Suo XG, Wang F, Wei J, Wang ZJ, Sun T, Zhang MM, Wang YF, Shao BY, Guo JB, Li HD, Xie SS, Li C, Ge QL, Dong YH, Li XY, Jin J, Yu JT, Yang C, Meng XM, Chen HY, Wen JG, Wang JN
Free radical biology & medicine 2026 Feb 16;244:68-83
Free radical biology & medicine 2026 Feb 16;244:68-83
TBX21 knockdown attenuates neuroinflammation induced by intracerebral hemorrhage via the SIRT1-WDR5-H3K4me3 axis.
Zou Z, Liu Z, Zhang Z, Li X
Brain research bulletin 2025 Sep;229:111415
Brain research bulletin 2025 Sep;229:111415
NEAT1 promotes the perineural invasion of pancreatic cancer via the E2F1/GDNF axis.
Gu J, Wang Q, Mo J, Qin T, Qian W, Duan W, Han L, Wang Z, Ma Q, Ma J
Cancer letters 2025 Mar 31;613:217497
Cancer letters 2025 Mar 31;613:217497
The m6A hypermethylation-induced PIR overexpression regulates H3K4me3 and promotes tumorigenesis of uveal melanoma.
Tian H, Chen Y, Dong X, Fan X, Jia R
Cancer letters 2025 Jul 28;623:217729
Cancer letters 2025 Jul 28;623:217729
Targeting pancreatic cancer glutamine dependency confers vulnerability to GPX4-dependent ferroptosis.
Shen X, Chen Y, Tang Y, Lu P, Liu M, Mao T, Weng Y, Yu F, Liu Y, Tang Y, Wang L, Niu N, Xue J
Cell reports. Medicine 2025 Feb 18;6(2):101928
Cell reports. Medicine 2025 Feb 18;6(2):101928
EIF3D safeguards the homeostasis of key signaling pathways in human primed pluripotency.
Okubo C, Nakamura M, Sato M, Shichino Y, Mito M, Takashima Y, Iwasaki S, Takahashi K
Science advances 2025 Apr 11;11(15):eadq5484
Science advances 2025 Apr 11;11(15):eadq5484
Effect of subcutaneous adipose tissue-associated CSRP2 on the progression of prostate cancer via the WDR5/USP44 pathway.
Wang J, Liang Y, Wang K, Lin L, Peng X, Li W, Li Y, Liao H, Li J, Qiao L, Li L
American journal of cancer research 2024;14(11):5321-5337
American journal of cancer research 2024;14(11):5321-5337
Glucagon-like peptide-1 receptor agonist exendin 4 ameliorates diabetes-associated vascular calcification by regulating mitophagy through the AMPK signaling pathway.
Chen K, Jin HJ, Wu ZH, Zhang BF, Wu J, Huang ZY, Huang YP, Lu XW, Zheng XT
Molecular medicine (Cambridge, Mass.) 2024 May 8;30(1):58
Molecular medicine (Cambridge, Mass.) 2024 May 8;30(1):58
Transcriptional and epigenetic dysregulation impairs generation of proliferative neural stem and progenitor cells during brain aging.
Li M, Guo H, Carey M, Huang C
Nature aging 2024 Jan;4(1):62-79
Nature aging 2024 Jan;4(1):62-79
USP36 regulates the proliferation, survival, and differentiation of hFOB1.19 osteoblast.
Yan J, Gu X, Gao X, Shao Y, Ji M
Journal of orthopaedic surgery and research 2024 Aug 17;19(1):483
Journal of orthopaedic surgery and research 2024 Aug 17;19(1):483
HPV E7-drived ALKBH5 promotes cervical cancer progression by modulating m6A modification of PAK5.
Huo FC, Zhu ZM, Du WQ, Pan YJ, Jiang X, Kang MJ, Liu BW, Mou J, Pei DS
Pharmacological research 2023 Sep;195:106863
Pharmacological research 2023 Sep;195:106863
KMT2A associates with PHF5A-PHF14-HMG20A-RAI1 subcomplex in pancreatic cancer stem cells and epigenetically regulates their characteristics.
Mouti MA, Deng S, Pook M, Malzahn J, Rendek A, Militi S, Nibhani R, Soonawalla Z, Oppermann U, Hwang CI, Pauklin S
Nature communications 2023 Sep 14;14(1):5685
Nature communications 2023 Sep 14;14(1):5685
A MYC inhibitor selectively alters the MYC and MAX cistromes and modulates the epigenomic landscape to regulate target gene expression.
Holmes AG, Parker JB, Sagar V, Truica MI, Soni PN, Han H, Schiltz GE, Abdulkadir SA, Chakravarti D
Science advances 2022 Apr 29;8(17):eabh3635
Science advances 2022 Apr 29;8(17):eabh3635
Compensatory functions of histone deacetylase 1 (HDAC1) and HDAC2 regulate transcription and apoptosis during mouse oocyte development.
Ma P, Pan H, Montgomery RL, Olson EN, Schultz RM
Proceedings of the National Academy of Sciences of the United States of America 2012 Feb 21;109(8):E481-9
Proceedings of the National Academy of Sciences of the United States of America 2012 Feb 21;109(8):E481-9
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 15544-1-AP(WDR5 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 15544-1-AP(WDR5 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The WDR5 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human WDR5. This antibody recognizes human,mouse,rat antigen. The WDR5 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
