66851-1-Ig

antibody from Proteintech Group

Targeting: SMO FZD11, SMOH

Provider product page for 66851-1-Ig

Western blot

ELISA

Immunocytochemistry

Antibody data

Antibody Data
Antigen structure
References [21]
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Product number: 66851-1-Ig - Provider product page
Provider: Proteintech Group
Product name: SMO antibody
Antibody type: Monoclonal
Description: SMO antibody (Cat. #66851-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, Canine, Mouse, Rat and has been validated for the following applications: IF, WB,ELISA.
Reactivity: Human, Mouse, Rat, Canine
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Antibody clone number: 2B10A11
Vial size: 20ul, 150ul

SMO protein structure - 66851-1-Ig shown in red.

Submitted references Pilose antler extract promotes hair growth in androgenic alopecia mice by promoting the initial anagen phase.

Liu M, He G, Wang F, Sun Y, Ma S, Hao Y, Wang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116503

Human umbilical cord mesenchymal stem cell-derived exosomes ameliorate renal fibrosis in diabetic nephropathy by targeting Hedgehog/SMO signaling.

Zhang K, Zheng S, Wu J, He J, Ouyang Y, Ao C, Lang R, Jiang Y, Yang Y, Xiao H, Li Y, Li M, Wang H, Li C, Wu D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23599

Leonurine Regulates Hippocampal Nerve Regeneration in Rats with Chronic and Unpredictable Mild Stress by Activating SHH/GLI Signaling Pathway and Restoring Gut Microbiota and Microbial Metabolic Homeostasis.

Meng P, Zhang X, Li D, Yang H, Lin X, Zhao H, Li P, Wang Y, Wang X, Ge J
Neural plasticity 2023;2023:1455634

Drug Repurposing Flubendazole to Suppress Tumorigenicity via PCSK9-dependent Inhibition and Potentiate Lenvatinib Therapy for Hepatocellular Carcinoma.

Jin W, Yu J, Su Y, Lin H, Liu T, Chen J, Ge C, Zhao F, Geng Q, Mao L, Jiang S, Cui Y, Chen T, Jiang G, Li J, Miao C, Xiao X, Li H
International journal of biological sciences 2023;19(7):2270-2288

Itraconazole inhibits proliferation, induces apoptosis, and reduces angiogenesis of hemangioma endothelial cells by downregulating the hedgehog signaling pathway.

Dong J, Cui J, Shi X, Wang T, Liu S
Heliyon 2023 Sep;9(9):e19244

Inhibition of CK2α accelerates skin wound healing by promoting endothelial cell proliferation through the Hedgehog signaling pathway.

Zhu J, Chen P, Liang J, Wu Z, Jin H, Xu T, Zheng Y, Ma H, Cong W, Wang X, Guan X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Sep;37(9):e23135

Adipose-derived mesenchymal stem cells-sourced exosomal microRNA-7846-3p suppresses proliferation and pro-angiogenic role of keloid fibroblasts by suppressing neuropilin 2.

Wu D, Liu X, Jin Z
Journal of cosmetic dermatology 2023 Aug;22(8):2333-2342

Mutational burden of XPNPEP3 leads to defects in mitochondrial complex I and cilia in NPHPL1.

Tong L, Rao J, Yang C, Xu J, Lu Y, Zhang Y, Cang X, Xie S, Mao J, Jiang P
iScience 2023 Aug 18;26(8):107446

SMO mutation predicts the effect of immune checkpoint inhibitor: From NSCLC to multiple cancers.

Ji W, Niu X, Yu Y, Li Z, Gu L, Lu S
Frontiers in immunology 2022;13:955800

Curcumin inhibits the invasion and metastasis of triple negative breast cancer via Hedgehog/Gli1 signaling pathway.

Li M, Guo T, Lin J, Huang X, Ke Q, Wu Y, Fang C, Hu C
Journal of ethnopharmacology 2022 Jan 30;283:114689

4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone provokes progression from chronic pancreatitis to pancreatic intraepithelial neoplasia.

Chen X, Sheng L, Ma J, Qi D, Li X, Wang Z, Wu Z, Wong L, Huang JH, Wu E, Ma Q, Zhang D
iScience 2022 Jan 21;25(1):103647

SPRY1 promotes cell proliferation and inhibits apoptosis by activating Hedgehog pathway in acute myeloid leukemia.

Lv G, Wang Y, Ji C, Shi C, Li Y
Hematology (Amsterdam, Netherlands) 2022 Dec;27(1):1-10

Microtubule Stabilization Enhances the Chondrogenesis of Synovial Mesenchymal Stem Cells.

Li J, Sun Z, Lv Z, Jiang H, Liu A, Wang M, Tan G, Guo H, Sun H, Wu R, Xu X, Yan W, Jiang Q, Ikegawa S, Shi D
Frontiers in cell and developmental biology 2021;9:748804

Resveratrol Inhibition of Renal Cancer Stem Cell Characteristics and Modulation of the Sonic Hedgehog Pathway.

Sun H, Zhang T, Liu R, Cao W, Zhang Z, Liu Z, Qian W, Wang D, Yu D, Zhong C
Nutrition and cancer 2021;73(7):1157-1167

Mitochondrial Protection and Against Glutamate Neurotoxicity via Shh/Ptch1 Signaling Pathway to Ameliorate Cognitive Dysfunction by Kaixin San in Multi-Infarct Dementia Rats.

Li X, Wen W, Li P, Fu Y, Chen H, Wang F, Dai Y, Xu S
Oxidative medicine and cellular longevity 2021;2021:5590745

Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.

Guo K, Wang P, Zhang L, Zhou Y, Dai X, Yan Y, Chen Y, Wasan HS, Yu J, Ruan S, Sun L
Cancer science 2021 Oct;112(10):4176-4186

Benzidine promotes the stemness of bladder cancer stem cells via activation of the Sonic hedgehog pathway.

Wang D, Xie D, Bi L, Wang Y, Zou C, Chen L, Geng H, Qian W, Li Y, Sun H, Wang X, Lu Y, Yu D, Zhong C
Oncology letters 2021 Feb;21(2):146

Procyanidin B2 alleviates liver injury caused by cold stimulation through Sonic hedgehog signalling and autophagy.

Ma L, Li C, Lian S, Xu B, Lv H, Liu Y, Lu J, Ji H, Li S, Guo J, Yang H
Journal of cellular and molecular medicine 2021 Aug;25(16):8015-8027

Rab1A promotes cell proliferation and migration by upregulating Gli1 in colorectal cancer.

Peng C, Li X, Ye Z, Wu W
Scientific reports 2021 Aug 10;11(1):16243

A Novel Cerebroprotein Hydrolysate, CH1, Ameliorates Chronic Focal Cerebral Ischemia Injury by Promoting White Matter Integrity via the Shh/Ptch-1/Gli-1 Signaling Pathway.

Cao W, Zhang C, Chen R, Wu Q, Xu R, Zhang L, Zhang X
Neuropsychiatric disease and treatment 2020;16:3209-3224

NRF2-dependent gene expression promotes ciliogenesis and Hedgehog signaling.

Martin-Hurtado A, Martin-Morales R, Robledinos-Antón N, Blanco R, Palacios-Blanco I, Lastres-Becker I, Cuadrado A, Garcia-Gonzalo FR
Scientific reports 2019 Sep 25;9(1):13896

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