Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- Other assay [1]
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Validation data
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- Product number
- PA5-40316 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- TEAD2 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- Peptide sequence: SGGFYGVSSQ YESLEHMTLT CSSKVCSFGK QVVEKVETER AQLEDGRFVY Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%; Zebrafish: 100%
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 0.5 mg/mL
- Storage
- -20° C, Avoid Freeze/Thaw Cycles
Submitted references Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription.
MicroRNA‑608 sensitizes non‑small cell lung cancer cells to cisplatin by targeting TEAD2.
Li Q, Sun Y, Jarugumilli GK, Liu S, Dang K, Cotton JL, Xiol J, Chan PY, DeRan M, Ma L, Li R, Zhu LJ, Li JH, Leiter AB, Ip YT, Camargo FD, Luo X, Johnson RL, Wu X, Mao J
Cell stem cell 2020 May 7;26(5):675-692.e8
Cell stem cell 2020 May 7;26(5):675-692.e8
MicroRNA‑608 sensitizes non‑small cell lung cancer cells to cisplatin by targeting TEAD2.
Wang Y, Li F, Ma D, Gao Y, Li R, Gao Y
Molecular medicine reports 2019 Oct;20(4):3519-3526
Molecular medicine reports 2019 Oct;20(4):3519-3526
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of human HT1080 cell lysate using an anti-TEAD2 polyclonal antibody (Product # PA5-40316).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 3. TEAD2 expression is repressed by miR-608 in non-small cell lung cancer cells. (A) Overexpression of miR-608 decreased the mRNA expression level of TEAD2 in A549 cells. (B) Overexpression of miR-608 decreased the protein expression level of TEAD2 in A549 cells. (C) Semi-quantification of TEAD2 protein expression levels. (D) Downregulation of miR-608 increased the mRNA expression level of TEAD2 in A549 cells. (E) Downregulation of miR-608 increased the protein expression level of TEAD2 in A549 cells. (F) Semi-quantification of TEAD2 protein expression levels. **P