Antibody data
- Antibody Data
- Antigen structure
- References [25]
- Comments [0]
- Validations
- Immunohistochemistry [1]
- Flow cytometry [1]
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Validation data
Reference
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- Product number
- 55491-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- VGLUT1 antibody
- Antibody type
- Polyclonal
- Description
- VGLUT1 antibody (Cat. #55491-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IHC,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Exendin-4 enhances GLP-1 signaling and reduces anxiety-like behaviors in male heroin withdrawal mice.
Supplementation of glucomannans ameliorate high-fat diet-induced cognitive impairment via a gut microbiota-metabolite-glutamatergic synapse axis.
Microglial activation drives neuronal dysregulation in alcohol-induced seizure susceptibility.
Ectoparasites enhance survival by suppressing host exploration and limiting dispersal.
Noninvasive Optogenetics Realized by iPSC-Derived Tentacled Carrier in Alzheimer's Disease Treatment.
Adiphenine Alleviates Impulsive-Like Behaviors in Aged Mice by Inhibiting Nicotinic Acetylcholine Receptors.
Melatonin alleviates retinal injury induced by vigabatrin and partially enhances its antiepileptic effects.
A neuronal Slit1-dependent program rescues oligodendrocyte differentiation and myelination under chronic hypoxic conditions.
Scraping Assay as a Novel Strategy to Evaluate Axonal Regeneration Using Human-Induced Pluripotent Stem Cell-Derived Neurons.
Differential toxic and antiepileptic features of Vigabatrin raceme and its enantiomers.
Small Molecule Hydrogels Loading Small Molecule Drugs from Chinese Medicine for the Enhanced Treatment of Traumatic Brain Injury.
Construction of functional neural network tissue combining CBD-NT3-modified linear-ordered collagen scaffold and TrkC-modified iPSC-derived neural stem cells for spinal cord injury repair.
The Traf2 and NcK interacting kinase inhibitor NCB-0846 suppresses seizure activity involving the decrease of GRIA1.
Transmembrane protein modulates seizure in epilepsy: evidence from temporal lobe epilepsy patients and mouse models.
Human induced pluripotent stem cell/embryonic stem cell-derived pyramidal neuronal precursors show safety and efficacy in a rat spinal cord injury model.
Membrane remodeling by FAM92A1 during brain development regulates neuronal morphology, synaptic function, and cognition.
Icariin rescues developmental BPA exposure induced spatial memory deficits in rats.
The anterior cingulate cortex controls the hyperactivity in subthalamic neurons in male mice with comorbid chronic pain and depression.
Insula→Amygdala and Insula→Thalamus Pathways Are Involved in Comorbid Chronic Pain and Depression-Like Behavior in Mice.
Directed Neural Stem Cells Differentiation via Signal Communication with Ni-Zn Micromotors.
Dendritic spine formation and synapse maturation in transcription factor-induced human iPSC-derived neurons.
GRN-/- iPSC-derived cortical neurons recapitulate the pathological findings of both frontotemporal lobar degeneration and neuronal ceroidolipofuscinosis.
CRISPR/Cas9-mediated genetic correction reverses spinocerebellar ataxia 3 disease-associated phenotypes in differentiated cerebellar neurons.
Depletion of Intracellular Glutamine Pools Triggers Toxoplasma gondii Stage Conversion in Human Glutamatergic Neurons.
PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by influencing synaptic function in the primary motor cortex of rats.
Xiang Y, Yan X, Li R, Li C, Yin D, Luo C, Xiong Y, Hong Y, Li Y, Xia B
PloS one 2026;21(3):e0343995
PloS one 2026;21(3):e0343995
Supplementation of glucomannans ameliorate high-fat diet-induced cognitive impairment via a gut microbiota-metabolite-glutamatergic synapse axis.
Cao Z, Liu H, Chen P, Yang S, Li X, Chen Z, Feng J, Chen L, Lin J, Fu Z, Nie Q, Li Z
International journal of biological macromolecules 2026 Apr;357:151705
International journal of biological macromolecules 2026 Apr;357:151705
Microglial activation drives neuronal dysregulation in alcohol-induced seizure susceptibility.
Zhang S, Zhou Y, Ren Y, Shang J, Jiang A, Hong Y, Hong S, Wang C, Wang W, Chen J
Scientific reports 2025 Nov 3;15(1):38389
Scientific reports 2025 Nov 3;15(1):38389
Ectoparasites enhance survival by suppressing host exploration and limiting dispersal.
Liu P, Ren D, Li G, Xu X, Presotto L, Liu W, Zhao N, Li D, Chen M, Wang J, Liu X, Zhao C, Lu L, Liu Q
Nature communications 2025 May 9;16(1):4318
Nature communications 2025 May 9;16(1):4318
Noninvasive Optogenetics Realized by iPSC-Derived Tentacled Carrier in Alzheimer's Disease Treatment.
Zhai Y, Gao F, Shi S, Zhong Q, Zhang J, Fang J, He F, Zhang Y, Li Y, Liu F, Xue B, Gu Y, Li S
Advanced materials (Deerfield Beach, Fla.) 2025 Aug;37(32):e2419768
Advanced materials (Deerfield Beach, Fla.) 2025 Aug;37(32):e2419768
Adiphenine Alleviates Impulsive-Like Behaviors in Aged Mice by Inhibiting Nicotinic Acetylcholine Receptors.
Peng HY, Gao YL, Wang LY, Lv JM, Miao HT, Li LY, Song RX, Zhou TT, An P, Zhao XC, Zhang LM
Journal of neurochemistry 2025 Aug;169(8):e70190
Journal of neurochemistry 2025 Aug;169(8):e70190
Melatonin alleviates retinal injury induced by vigabatrin and partially enhances its antiepileptic effects.
Ma M, Fan M, Xu S, Zheng Q, Wang C, Chen P, Wei Y, Ge J
International immunopharmacology 2025 Apr 24;153:114516
International immunopharmacology 2025 Apr 24;153:114516
A neuronal Slit1-dependent program rescues oligodendrocyte differentiation and myelination under chronic hypoxic conditions.
Dai W, Nian X, Zhou Z, Du A, Liu Q, Jia S, Lu Y, Li D, Lu X, Zhu Y, Huang Q, Lu J, Xiao Y, Zheng L, Lei W, Sheng N, Zang X, Hou Y, Qiu Z, Xu R, Xu S, Zhang X, Zhang L
Cell reports 2025 Apr 22;44(4):115467
Cell reports 2025 Apr 22;44(4):115467
Scraping Assay as a Novel Strategy to Evaluate Axonal Regeneration Using Human-Induced Pluripotent Stem Cell-Derived Neurons.
Oonishi T, Nishimura K, Takata K, Fujimuro M, Sekine Y
Biological & pharmaceutical bulletin 2024;47(2):366-372
Biological & pharmaceutical bulletin 2024;47(2):366-372
Differential toxic and antiepileptic features of Vigabatrin raceme and its enantiomers.
Xu SL, Fan M, Ma MD, Zheng Q, Chen PQ, Wei YD, Sun HM, Sun HZ, Ge JF
Brain research 2024 Sep 1;1838:148991
Brain research 2024 Sep 1;1838:148991
Small Molecule Hydrogels Loading Small Molecule Drugs from Chinese Medicine for the Enhanced Treatment of Traumatic Brain Injury.
Luo W, Yang Z, Zheng J, Cai Z, Li X, Liu J, Guo X, Luo M, Fan X, Cheng M, Tang T, Liu J, Wang Y
ACS nano 2024 Oct 22;18(42):28894-28909
ACS nano 2024 Oct 22;18(42):28894-28909
Construction of functional neural network tissue combining CBD-NT3-modified linear-ordered collagen scaffold and TrkC-modified iPSC-derived neural stem cells for spinal cord injury repair.
Wu Z, Zhou Y, Hou X, Liu W, Yin W, Wang L, Cao Y, Jiang Z, Guo Y, Chen Q, Xie W, Wang Z, Shi N, Liu Y, Gao X, Luo L, Dai J, Ren C, Jiang X
Bioactive materials 2024 May;35:242-258
Bioactive materials 2024 May;35:242-258
The Traf2 and NcK interacting kinase inhibitor NCB-0846 suppresses seizure activity involving the decrease of GRIA1.
Wang M, Gu Y, Li Q, Feng B, Lv X, Zhang H, Kong Q, Dong Z, Tian X, Zhang Y
Genes & diseases 2024 May;11(3):100997
Genes & diseases 2024 May;11(3):100997
Transmembrane protein modulates seizure in epilepsy: evidence from temporal lobe epilepsy patients and mouse models.
Zhang H, Zhou Z, Qin J, Yang J, Huang H, Yang X, Luo Z, Zheng Y, Peng Y, Chen Y, Xu Z
Experimental animals 2024 May 3;73(2):162-174
Experimental animals 2024 May 3;73(2):162-174
Human induced pluripotent stem cell/embryonic stem cell-derived pyramidal neuronal precursors show safety and efficacy in a rat spinal cord injury model.
Li M, Qi B, Li Q, Zheng T, Wang Y, Liu B, Guan Y, Bai Y, Jian F, Xu ZD, Xu Q, Chen Z
Cellular and molecular life sciences : CMLS 2024 Jul 29;81(1):318
Cellular and molecular life sciences : CMLS 2024 Jul 29;81(1):318
Membrane remodeling by FAM92A1 during brain development regulates neuronal morphology, synaptic function, and cognition.
Wang L, Yang Z, Satoshi F, Prasanna X, Yan Z, Vihinen H, Chen Y, Zhao Y, He X, Bu Q, Li H, Zhao Y, Jiang L, Qin F, Dai Y, Zhang N, Qin M, Kuang W, Zhao Y, Jokitalo E, Vattulainen I, Kajander T, Zhao H, Cen X
Nature communications 2024 Jul 23;15(1):6209
Nature communications 2024 Jul 23;15(1):6209
Icariin rescues developmental BPA exposure induced spatial memory deficits in rats.
Li D, Ai S, Huang C, Liu ZH, Wang HL
Toxicology and applied pharmacology 2024 Jan;482:116776
Toxicology and applied pharmacology 2024 Jan;482:116776
The anterior cingulate cortex controls the hyperactivity in subthalamic neurons in male mice with comorbid chronic pain and depression.
Wang YD, Bao ST, Gao Y, Chen J, Jia T, Yin C, Cao JL, Xiao C, Zhou C
PLoS biology 2024 Feb;22(2):e3002518
PLoS biology 2024 Feb;22(2):e3002518
Insula→Amygdala and Insula→Thalamus Pathways Are Involved in Comorbid Chronic Pain and Depression-Like Behavior in Mice.
Chen J, Gao Y, Bao ST, Wang YD, Jia T, Yin C, Xiao C, Zhou C
The Journal of neuroscience : the official journal of the Society for Neuroscience 2024 Apr 10;44(15)
The Journal of neuroscience : the official journal of the Society for Neuroscience 2024 Apr 10;44(15)
Directed Neural Stem Cells Differentiation via Signal Communication with Ni-Zn Micromotors.
Feng Y, Gao C, Xie D, Liu L, Chen B, Liu S, Yang H, Gao Z, Wilson DA, Tu Y, Peng F
Advanced materials (Deerfield Beach, Fla.) 2023 Sep;35(35):e2301736
Advanced materials (Deerfield Beach, Fla.) 2023 Sep;35(35):e2301736
Dendritic spine formation and synapse maturation in transcription factor-induced human iPSC-derived neurons.
Lin W, Shiomoto S, Yamada S, Watanabe H, Kawashima Y, Eguchi Y, Muramatsu K, Sekino Y
iScience 2023 Apr 21;26(4):106285
iScience 2023 Apr 21;26(4):106285
GRN-/- iPSC-derived cortical neurons recapitulate the pathological findings of both frontotemporal lobar degeneration and neuronal ceroidolipofuscinosis.
Bossolasco P, Cimini S, Maderna E, Bardelli D, Canafoglia L, Cavallaro T, Ricci M, Silani V, Marucci G, Rossi G
Neurobiology of disease 2022 Dec;175:105891
Neurobiology of disease 2022 Dec;175:105891
CRISPR/Cas9-mediated genetic correction reverses spinocerebellar ataxia 3 disease-associated phenotypes in differentiated cerebellar neurons.
Song G, Ma Y, Gao X, Zhang X, Zhang F, Tian C, Hou J, Liu Z, Zhao Z, Tian Y
Life medicine 2022 Aug;1(1):27-44
Life medicine 2022 Aug;1(1):27-44
Depletion of Intracellular Glutamine Pools Triggers Toxoplasma gondii Stage Conversion in Human Glutamatergic Neurons.
Bando H, Fukuda Y, Watanabe N, Olawale JT, Kato K
Frontiers in cellular and infection microbiology 2021;11:788303
Frontiers in cellular and infection microbiology 2021;11:788303
PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by influencing synaptic function in the primary motor cortex of rats.
Mo J, Wang B, Zhu X, Wu X, Liu Y
Neurobiology of disease 2019 Jan;121:274-285
Neurobiology of disease 2019 Jan;121:274-285
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 55491-1-AP(SLC17A7 antibody) at dilution of 1:50 (under 10x lens)
- Other comments
- IHC
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The VGLUT1 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human VGLUT1. This antibody recognizes human antigen. The VGLUT1 antibody has been validated for the following applications: ELISA, IHC, FC analysis.