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- Antibody Data
- Antigen structure
- References [13]
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- Validations
- Immunohistochemistry [1]
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- Product number
- AMAb91041 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#AMAb91041, RRID:AB_2665777
- Product name
- Anti-VGLUT1
- Antibody type
- Monoclonal
- Description
- Monoclonal Antibody against Human SLC17A7, Clone ID: CL2754, Gene description: solute carrier family 17 member 7, Alternative Gene Names: SLC17A7, BNPI, Validated applications: WB, IHC, Uniprot ID: Q9P2U7, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- CL2754
- Vial size
- 100 µl
- Concentration
- 1.0 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Modeling antisense oligonucleotide therapy in MECP2 duplication syndrome human iPSC-derived neurons reveals gene expression programs responsive to MeCP2 levels
Neuroprotective Effects of VGLUT1 Inhibition in HT22 Cells Overexpressing VGLUT1 Under Oxygen Glucose Deprivation Conditions
Inhibition of Vesicular Glutamate Transporters (VGLUTs) with Chicago Sky Blue 6B Before Focal Cerebral Ischemia Offers Neuroprotection
Axonal plasticity in response to active forces generated through magnetic nano-pulling
Preferential expression of SCN1A in GABAergic neurons improves survival and epileptic phenotype in a mouse model of Dravet syndrome
In-vitro engineered human cerebral tissues mimic pathological circuit disturbances in 3D
Parkinson's disease motor symptoms rescue by CRISPRa‐reprogramming astrocytes into GABAergic neurons
Cross-species genetic screens identify transglutaminase 5 as a regulator of polyglutamine-expanded ataxin-1
Dual targeting of brain region‐specific kinases potentiates neurological rescue in Spinocerebellar ataxia type 1
Transfer of SCN1A to the brain of adolescent mouse model of Dravet syndrome improves epileptic, motor, and behavioral manifestations
Doublecortin-like Kinase 1 Regulates α-Synuclein Levels and Toxicity
Synaptic Organization of VGLUT3 Expressing Low-Threshold Mechanosensitive C Fiber Terminals in the Rodent Spinal Cord.
Bajikar S, Sztainberg Y, Trostle A, Tirumala H, Wan Y, Harrop C, Bengtsson J, Carvalho C, Pehlivan D, Suter B, Neul J, Liu Z, Jafar-Nejad P, Rigo F, Zoghbi H
Human Molecular Genetics 2024;33(22):1986-2001
Human Molecular Genetics 2024;33(22):1986-2001
Neuroprotective Effects of VGLUT1 Inhibition in HT22 Cells Overexpressing VGLUT1 Under Oxygen Glucose Deprivation Conditions
Pomierny B, Krzyżanowska W, Skórkowska A, Budziszewska B, Pera J
NeuroMolecular Medicine 2024;26(1)
NeuroMolecular Medicine 2024;26(1)
Inhibition of Vesicular Glutamate Transporters (VGLUTs) with Chicago Sky Blue 6B Before Focal Cerebral Ischemia Offers Neuroprotection
Pomierny B, Krzyżanowska W, Skórkowska A, Jurczyk J, Bystrowska B, Budziszewska B, Pera J
Molecular Neurobiology 2023;60(6):3130-3146
Molecular Neurobiology 2023;60(6):3130-3146
Axonal plasticity in response to active forces generated through magnetic nano-pulling
Falconieri A, De Vincentiis S, Cappello V, Convertino D, Das R, Ghignoli S, Figoli S, Luin S, Català-Castro F, Marchetti L, Borello U, Krieg M, Raffa V
Cell Reports 2023;42(1):111912
Cell Reports 2023;42(1):111912
Preferential expression of SCN1A in GABAergic neurons improves survival and epileptic phenotype in a mouse model of Dravet syndrome
Ricobaraza A, Bunuales M, Gonzalez-Aparicio M, Fadila S, Rubinstein M, Vides-Urrestarazu I, Banderas J, Sola-Sevilla N, Sanchez-Carpintero R, Lanciego J, Roda E, Honrubia A, Arnaiz P, Hernandez-Alcoceba R
Journal of Molecular Medicine 2023;101(12):1587-1601
Journal of Molecular Medicine 2023;101(12):1587-1601
In-vitro engineered human cerebral tissues mimic pathological circuit disturbances in 3D
Saberi A, Aldenkamp A, Kurniawan N, Bouten C
Communications Biology 2022;5(1)
Communications Biology 2022;5(1)
Parkinson's disease motor symptoms rescue by CRISPRa‐reprogramming astrocytes into GABAergic neurons
Giehrl‐Schwab J, Giesert F, Rauser B, Lao C, Hembach S, Lefort S, Ibarra I, Koupourtidou C, Luecken M, Truong D, Fischer‐Sternjak J, Masserdotti G, Prakash N, Ninkovic J, Hölter S, Vogt Weisenhorn D, Theis F, Götz M, Wurst W
EMBO Molecular Medicine 2022;14(5)
EMBO Molecular Medicine 2022;14(5)
Cross-species genetic screens identify transglutaminase 5 as a regulator of polyglutamine-expanded ataxin-1
Lee W, Al-Ramahi I, Jeong H, Jang Y, Lin T, Adamski C, Lavery L, Rath S, Richman R, Bondar V, Alcala E, Revelli J, Orr H, Liu Z, Botas J, Zoghbi H
Journal of Clinical Investigation 2022;132(9)
Journal of Clinical Investigation 2022;132(9)
Dual targeting of brain region‐specific kinases potentiates neurological rescue in Spinocerebellar ataxia type 1
Lee W, Lavery L, Rousseaux M, Rutledge E, Jang Y, Wan Y, Wu S, Kim W, Al‐Ramahi I, Rath S, Adamski C, Bondar V, Tewari A, Soleimani S, Mota S, Yalamanchili H, Orr H, Liu Z, Botas J, Zoghbi H
The EMBO Journal 2021;40(7)
The EMBO Journal 2021;40(7)
Transfer of SCN1A to the brain of adolescent mouse model of Dravet syndrome improves epileptic, motor, and behavioral manifestations
Mora-Jimenez L, Valencia M, Sanchez-Carpintero R, Tønnesen J, Fadila S, Rubinstein M, Gonzalez-Aparicio M, Bunuales M, Fernandez-Pierola E, Nicolas M, Puerta E, Miguelez C, Minguez P, Lumbreras S, Gonzalez-Aseguinolaza G, Ricobaraza A, Hernandez-Alcoceba R
Molecular Therapy - Nucleic Acids 2021;25
Molecular Therapy - Nucleic Acids 2021;25
Doublecortin-like Kinase 1 Regulates α-Synuclein Levels and Toxicity
Vázquez-Vélez G, Gonzales K, Revelli J, Adamski C, Alavi Naini F, Bajić A, Craigen E, Richman R, Heman-Ackah S, Wood M, Rousseaux M, Zoghbi H
The Journal of Neuroscience 2020;40(2):459-477
The Journal of Neuroscience 2020;40(2):459-477
Tristan C, Ormanoglu P, Slamecka J, Malley C, Chu P, Jovanovic V, Gedik Y, Bonney C, Barnaeva E, Braisted J, Mallanna S, Dorjsuren D, Iannotti M, Voss T, Michael S, Simeonov A, Singeç I
2020
2020
Synaptic Organization of VGLUT3 Expressing Low-Threshold Mechanosensitive C Fiber Terminals in the Rodent Spinal Cord.
Larsson M, Broman J
eNeuro 2019 Jan-Feb;6(1)
eNeuro 2019 Jan-Feb;6(1)
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human cerebral cortex and tonsil tissues using AMAb91041 antibody. Corresponding VGLUT1 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
