Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 20313-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20313-1-AP, RRID:AB_10697658
- Product name
- GBE1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GBE1 antibody (Cat. #20313-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A novel genetic model provides a unique perspective on the relationship between postexercise glycogen concentration and increases in the abundance of key metabolic proteins after acute exercise.
Induced pluripotent stem cell (iPSC) modeling validates reduced GBE1 enzyme activity due to a novel variant, p.Ile694Asn, found in a patient with suspected glycogen storage disease IV.
PYGL-mediated glucose metabolism reprogramming promotes EMT phenotype and metastasis of pancreatic cancer.
MYCT1 alters the glycogen shunt by regulating selective translation of RACK1-mediated enzymes.
Liver fibrosis alters the molecular structures of hepatic glycogen.
Loss of C2orf69 defines a fatal autoinflammatory syndrome in humans and zebrafish that evokes a glycogen-storage-associated mitochondriopathy.
Hallmarks of oxidative stress in the livers of aged mice with mild glycogen branching enzyme deficiency.
Global Phosphoproteomic Analysis Reveals Significant Metabolic Reprogramming in the Termination of Liver Regeneration in Mice.
Kwak SE, Zheng A, Arias EB, Wang H, Pan X, Yue Y, Duan D, Cartee GD
PloS one 2024;19(1):e0295964
PloS one 2024;19(1):e0295964
Induced pluripotent stem cell (iPSC) modeling validates reduced GBE1 enzyme activity due to a novel variant, p.Ile694Asn, found in a patient with suspected glycogen storage disease IV.
Naito C, Kosar K, Kishimoto E, Pena L, Huang Y, Hao K, Bernieh A, Kasten J, Villa C, Kishnani P, Deeksha B, Gu M, Asai A
Molecular genetics and metabolism reports 2024 Jun;39:101069
Molecular genetics and metabolism reports 2024 Jun;39:101069
PYGL-mediated glucose metabolism reprogramming promotes EMT phenotype and metastasis of pancreatic cancer.
Ji Q, Li H, Cai Z, Yuan X, Pu X, Huang Y, Fu S, Chu L, Jiang C, Xue J, Zhang X, Li R
International journal of biological sciences 2023;19(6):1894-1909
International journal of biological sciences 2023;19(6):1894-1909
MYCT1 alters the glycogen shunt by regulating selective translation of RACK1-mediated enzymes.
Ding DX, Wang Y, Yan W, Fu WN
iScience 2022 Mar 18;25(3):103955
iScience 2022 Mar 18;25(3):103955
Liver fibrosis alters the molecular structures of hepatic glycogen.
Wan Y, Hu Z, Liu Q, Wang L, Sullivan MA, Gilbert RG
Carbohydrate polymers 2022 Feb 15;278:118991
Carbohydrate polymers 2022 Feb 15;278:118991
Loss of C2orf69 defines a fatal autoinflammatory syndrome in humans and zebrafish that evokes a glycogen-storage-associated mitochondriopathy.
Wong HH, Seet SH, Maier M, Gurel A, Traspas RM, Lee C, Zhang S, Talim B, Loh AYT, Chia CY, Teoh TS, Sng D, Rensvold J, Unal S, Shishkova E, Cepni E, Nathan FM, Sirota FL, Liang C, Yarali N, Simsek-Kiper PO, Mitani T, Ceylaner S, Arman-Bilir O, Mbarek H, Gumruk F, Efthymiou S, Uğurlu Çi Men D, Georgiadou D, Sotiropoulou K, Houlden H, Paul F, Pehlivan D, Lainé C, Chai G, Ali NA, Choo SC, Keng SS, Boisson B, Yılmaz E, Xue S, Coon JJ, Ly TTN, Gilani N, Hasbini D, Kayserili H, Zaki MS, Isfort RJ, Ordonez N, Tripolszki K, Bauer P, Rezaei N, Seyedpour S, Khotaei GT, Bascom CC, Maroofian R, Chaabouni M, Alsubhi A, Eyaid W, Işıkay S, Gleeson JG, Lupski JR, Casanova JL, Pagliarini DJ, Akarsu NA, Maurer-Stroh S, Cetinkaya A, Bertoli-Avella A, Mathuru AS, Ho L, Bard FA, Reversade B
American journal of human genetics 2021 Jul 1;108(7):1301-1317
American journal of human genetics 2021 Jul 1;108(7):1301-1317
Hallmarks of oxidative stress in the livers of aged mice with mild glycogen branching enzyme deficiency.
Malinska D, Testoni G, Duran J, Brudnicka A, Guinovart JJ, Duszynski J
Archives of biochemistry and biophysics 2020 Nov 30;695:108626
Archives of biochemistry and biophysics 2020 Nov 30;695:108626
Global Phosphoproteomic Analysis Reveals Significant Metabolic Reprogramming in the Termination of Liver Regeneration in Mice.
Zhang J, Tang N, Zhao Y, Zhao R, Fu X, Zhao D, Zhao Y, Huang L, Li C, Qiu Y, Xue B, Fang L
Journal of proteome research 2020 Apr 3;19(4):1788-1799
Journal of proteome research 2020 Apr 3;19(4):1788-1799
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The GBE1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human GBE1. This antibody recognizes human, mouse, rat antigen. The GBE1 antibody has been validated for the following applications: ELISA, WB analysis.