Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS60766 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- ARHGAP20 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human ARHGAP20
- Description
- GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins. ARHGAP20 (Rho GTPase activating protein 20), also known as KIAA1391, is a 1,191 amino acid protein that contains one PH domain, one Ras-associating domain and one Rho-GAP domain. Expressed primarily in brain, but also present in lymph nodes and fetal liver, ARHGAP20 functions as a GTPase-activating protein for Rho-type GTPases, effectively converting Rho-type GTPases to an inactive, GDP-bound state. ARHGAP20 exists as multiple isoforms that are produced via alternative splicing. Chromosomal aberrations involving the ARHGAP20 gene are thought to be a cause of B-cell chronic lymphocytic leukemia (B-CLL).
- Reactivity
- Human, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of ARHGAP20 pAb at 1:500 dilutionLane1:A549 whole cell lysateLane2:PC12 whole cell lysate