BS60403
antibody from Bioworld Technology, Inc
Targeting: IMMT
HMP, Mic60, MICOS60, MINOS2, P87, P89
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- BS60403 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- Mitofilin polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human Mitofilin.
- Description
- Cristae are highly folded inner mitochondrial membrane compartments that are studded with cytochromes and ATP synthase proteins and function to provide a large surface area upon which cellular respiration can occur. Mitofilin, also known as IMMT, HMP, PIG4 or P87/89, is a 758 amino acid inner mitochondrial membrane protein that is preferentially expressed in heart tissue. Existing as three alternatively spliced isoforms, Mitofilin functions to control mitochondrial cristae morphology, including the formation and organization of cristae junctions and normal tubular cristae. Due to its role in mediating cristae structure and function, Mitofilin is essential for normal mitochondrial function and is, thus, critical to overall cell survival.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of Mitofilin pAb at 1:500 dilutionLane1:MCF-7 cell lysateLane2:sp2/0 cell lysateLane3:PC12 cell lysate