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Learn17627-1-AP
antibody from Proteintech Group
Targeting: ASCC3
ASC1p200, dJ121G13.4, dJ467N11.1, HELIC1, RNAH
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 17627-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17627-1-AP, RRID:AB_2059474
- Product name
- ASCC3 antibody
- Antibody type
- Polyclonal
- Description
- ASCC3 antibody (Cat. #17627-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ASCC3 promotes chemosensitivity in colorectal cancer cells.
The Ski2 helicase ASCC3 unwinds DNA upon fork stalling to control replication stress responses.
Pan-cancer analysis reveals ASCC family promotes the cancer progression of lung adenocarcinoma.
Girolline is a sequence context-selective modulator of eIF5A activity.
Ribosome Quality Control mitigates the cytotoxicity of ribosome collisions induced by 5-Fluorouracil.
Stalled translation by mitochondrial stress upregulates a CNOT4-ZNF598 ribosomal quality control pathway important for tissue homeostasis.
The ASC-1 complex promotes translation initiation by scanning ribosomes.
Extended DNA threading through a dual-engine motor module of the activating signal co-integrator 1 complex.
Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response.
Unresolved stalled ribosome complexes restrict cell-cycle progression after genotoxic stress.
Identification of a novel trigger complex that facilitates ribosome-associated quality control in mammalian cells.
Tu A, Martyn RDC, Cui S, Batenburg NL, Fayyazi R, Di Pastena F, Berthiaume L, Singh K, Saleem R, Scott GR, Berg T, Audet-Walsh É, Steinberg GR, Zhu XD
Scientific reports 2026 Mar 17;16(1)
Scientific reports 2026 Mar 17;16(1)
The Ski2 helicase ASCC3 unwinds DNA upon fork stalling to control replication stress responses.
Cui S, Batenburg NL, Coulombe Y, Arumugam A, Walker JR, Sheida SV, Bielinsky AK, Wahl MC, Masson JY, Zhu XD
bioRxiv : the preprint server for biology 2025 Jul 26;
bioRxiv : the preprint server for biology 2025 Jul 26;
Pan-cancer analysis reveals ASCC family promotes the cancer progression of lung adenocarcinoma.
Pan Y, Tan J, Wu C, Liu C, Chen Z, Zhu Y, Luo F, Liu Q
Scientific reports 2025 Jul 2;15(1):22799
Scientific reports 2025 Jul 2;15(1):22799
Girolline is a sequence context-selective modulator of eIF5A activity.
Schneider-Poetsch T, Dang Y, Iwasaki W, Arata M, Shichino Y, Al Mourabit A, Moriou C, Romo D, Liu JO, Ito T, Iwasaki S, Yoshida M
Nature communications 2025 Jan 10;16(1):223
Nature communications 2025 Jan 10;16(1):223
Ribosome Quality Control mitigates the cytotoxicity of ribosome collisions induced by 5-Fluorouracil.
Chatterjee S, Naeli P, Onar O, Simms N, Garzia A, Hackett A, Coyle K, Harris Snell P, McGirr T, Sawant TN, Dang K, Stoichkova ZV, Azam Y, Saunders MP, Braun M, Alain T, Tuschl T, McDade SS, Longley DB, Gkogkas CG, Adrain C, Knight JRP, Jafarnejad SM
Nucleic acids research 2024 Nov 11;52(20):12534-12548
Nucleic acids research 2024 Nov 11;52(20):12534-12548
Stalled translation by mitochondrial stress upregulates a CNOT4-ZNF598 ribosomal quality control pathway important for tissue homeostasis.
Geng J, Li S, Li Y, Wu Z, Bhurtel S, Rimal S, Khan D, Ohja R, Brandman O, Lu B
Nature communications 2024 Feb 22;15(1):1637
Nature communications 2024 Feb 22;15(1):1637
The ASC-1 complex promotes translation initiation by scanning ribosomes.
Kito Y, Matsumoto A, Ichihara K, Shiraishi C, Tang R, Hatano A, Matsumoto M, Han P, Iwasaki S, Nakayama KI
The EMBO journal 2023 Jun 15;42(12):e112869
The EMBO journal 2023 Jun 15;42(12):e112869
Extended DNA threading through a dual-engine motor module of the activating signal co-integrator 1 complex.
Jia J, Hilal T, Bohnsack KE, Chernev A, Tsao N, Bethmann J, Arumugam A, Parmely L, Holton N, Loll B, Mosammaparast N, Bohnsack MT, Urlaub H, Wahl MC
Nature communications 2023 Apr 5;14(1):1886
Nature communications 2023 Apr 5;14(1):1886
Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response.
Snieckute G, Genzor AV, Vind AC, Ryder L, Stoneley M, Chamois S, Dreos R, Nordgaard C, Sass F, Blasius M, López AR, Brynjólfsdóttir SH, Andersen KL, Willis AE, Frankel LB, Poulsen SS, Gatfield D, Gerhart-Hines Z, Clemmensen C, Bekker-Jensen S
Cell metabolism 2022 Dec 6;34(12):2036-2046.e8
Cell metabolism 2022 Dec 6;34(12):2036-2046.e8
Unresolved stalled ribosome complexes restrict cell-cycle progression after genotoxic stress.
Stoneley M, Harvey RF, Mulroney TE, Mordue R, Jukes-Jones R, Cain K, Lilley KS, Sawarkar R, Willis AE
Molecular cell 2022 Apr 21;82(8):1557-1572.e7
Molecular cell 2022 Apr 21;82(8):1557-1572.e7
Identification of a novel trigger complex that facilitates ribosome-associated quality control in mammalian cells.
Hashimoto S, Sugiyama T, Yamazaki R, Nobuta R, Inada T
Scientific reports 2020 Feb 25;10(1):3422
Scientific reports 2020 Feb 25;10(1):3422
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ASCC3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ASCC3. This antibody recognizes human, mouse, rat antigen. The ASCC3 antibody has been validated for the following applications: ELISA, WB analysis.
