17627-1-AP
antibody from Proteintech Group
Targeting: ASCC3
ASC1p200, dJ121G13.4, dJ467N11.1, HELIC1, RNAH
Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 17627-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17627-1-AP, RRID:AB_2059474
- Product name
- ASCC3 antibody
- Antibody type
- Polyclonal
- Description
- ASCC3 antibody (Cat. #17627-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Stalled translation by mitochondrial stress upregulates a CNOT4-ZNF598 ribosomal quality control pathway important for tissue homeostasis.
Extended DNA threading through a dual-engine motor module of the activating signal co-integrator 1 complex.
Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response.
Unresolved stalled ribosome complexes restrict cell-cycle progression after genotoxic stress.
Identification of a novel trigger complex that facilitates ribosome-associated quality control in mammalian cells.
Geng J, Li S, Li Y, Wu Z, Bhurtel S, Rimal S, Khan D, Ohja R, Brandman O, Lu B
Nature communications 2024 Feb 22;15(1):1637
Nature communications 2024 Feb 22;15(1):1637
Extended DNA threading through a dual-engine motor module of the activating signal co-integrator 1 complex.
Jia J, Hilal T, Bohnsack KE, Chernev A, Tsao N, Bethmann J, Arumugam A, Parmely L, Holton N, Loll B, Mosammaparast N, Bohnsack MT, Urlaub H, Wahl MC
Nature communications 2023 Apr 5;14(1):1886
Nature communications 2023 Apr 5;14(1):1886
Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response.
Snieckute G, Genzor AV, Vind AC, Ryder L, Stoneley M, Chamois S, Dreos R, Nordgaard C, Sass F, Blasius M, López AR, Brynjólfsdóttir SH, Andersen KL, Willis AE, Frankel LB, Poulsen SS, Gatfield D, Gerhart-Hines Z, Clemmensen C, Bekker-Jensen S
Cell metabolism 2022 Dec 6;34(12):2036-2046.e8
Cell metabolism 2022 Dec 6;34(12):2036-2046.e8
Unresolved stalled ribosome complexes restrict cell-cycle progression after genotoxic stress.
Stoneley M, Harvey RF, Mulroney TE, Mordue R, Jukes-Jones R, Cain K, Lilley KS, Sawarkar R, Willis AE
Molecular cell 2022 Apr 21;82(8):1557-1572.e7
Molecular cell 2022 Apr 21;82(8):1557-1572.e7
Identification of a novel trigger complex that facilitates ribosome-associated quality control in mammalian cells.
Hashimoto S, Sugiyama T, Yamazaki R, Nobuta R, Inada T
Scientific reports 2020 Feb 25;10(1):3422
Scientific reports 2020 Feb 25;10(1):3422
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ASCC3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ASCC3. This antibody recognizes human, mouse, rat antigen. The ASCC3 antibody has been validated for the following applications: ELISA, WB analysis.