66797-1-Ig

antibody from Proteintech Group

Targeting: SOCS3 CIS3, Cish3, SOCS-3, SSI-3

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

66797-1-Ig

Provider

Proteintech Group

Product name

SOCS3 antibody

Antibody type

Monoclonal

Description

SOCS3 antibody (Cat. #66797-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.

Reactivity

Human, Mouse

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

1G2B12

Vial size

20ul, 150ul

References

Submitted references

Verapamil and tangeretin enhances the M1 macrophages to M2 type in lipopolysaccharide-treated mice and inhibits the P-glycoprotein expression by downregulating STAT1/STAT3 and upregulating SOCS3.

Kundu A, Ghosh P, Bishayi B
International immunopharmacology 2024 May 30;133:112153

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Endogenous blocking of TLR2 along with TNF-α and IL-1β ameliorates the severity of the S. aureus arthritis via modulating STAT3/SOCS3 expressions in tissue resident macrophages.

Ghosh R, Bishayi B
Microbial pathogenesis 2024 Feb;187:106518

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PTK6 inhibits autophagy to promote uveal melanoma tumorigenesis by binding to SOCS3 and regulating mTOR phosphorylation.

Liu B, Yao X, Zhang C, Liu Y, Wei L, Huang Q, Wang M, Zhang Y, Hu D, Wu W
Cell death & disease 2023 Jan 23;14(1):55

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Simiao San alleviates hyperuricemia and kidney inflammation by inhibiting NLRP3 inflammasome and JAK2/STAT3 signaling in hyperuricemia mice.

Zhang Y, Wang S, Dai X, Liu T, Liu Y, Shi H, Yin J, Xu T, Zhang Y, Zhao D, Sukhorukov V, Orekhov AN, Gao S, Wang L, Zhang D
Journal of ethnopharmacology 2023 Aug 10;312:116530

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Apigenin Ameliorates Hyperuricemia and Renal Injury through Regulation of Uric Acid Metabolism and JAK2/STAT3 Signaling Pathway.

Liu T, Gao H, Zhang Y, Wang S, Lu M, Dai X, Liu Y, Shi H, Xu T, Yin J, Gao S, Wang L, Zhang D
Pharmaceuticals (Basel, Switzerland) 2022 Nov 21;15(11)

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Epac activation ameliorates tubulointerstitial inflammation in diabetic nephropathy.

Yang WX, Liu Y, Zhang SM, Wang HF, Liu YF, Liu JL, Li XH, Zeng MR, Han YZ, Liu FY, Sun L, Xiao L
Acta pharmacologica Sinica 2022 Mar;43(3):659-671

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Single Treatment of Vitamin D3 Ameliorates LPS-Induced Acute Lung Injury through Changing Lung Rodentibacter abundance.

Jin A, Zhao Y, Yuan Y, Ma S, Chen J, Yang X, Lu S, Sun Q
Molecular nutrition & food research 2022 Feb;66(3):e2100952

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Investigation of the mechanism of Isobavachalcone in treating rheumatoid arthritis through a combination strategy of network pharmacology and experimental verification.

Wang S, Du Q, Sun J, Geng S, Zhang Y
Journal of ethnopharmacology 2022 Aug 10;294:115342

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Autophagy Drives Galectin-1 Secretion From Tumor-Associated Macrophages Facilitating Hepatocellular Carcinoma Progression.

Davuluri GVN, Chen CC, Chiu YC, Tsai HW, Chiu HC, Chen YL, Tsai PJ, Kuo WT, Tsao N, Lin YS, Chang CP
Frontiers in cell and developmental biology 2021;9:741820

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STAT3 and IL-6 Contribute to Corticosteroid Resistance in an OVA and Ozone-induced Asthma Model with Neutrophil Infiltration.

Xue Y, Zhou Y, Bao W, Fu Q, Hao H, Han L, Zhang X, Tian X, Zhang M
Frontiers in molecular biosciences 2021;8:717962

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Identification of the Prognostic Value Among Suppressor Of Cytokine Signaling Family Members in Kidney Renal Clear Cell Carcinoma.

Li C, Zhang W, Fang T, Li N, Wang Y, He L, He H
Frontiers in molecular biosciences 2021;8:585000

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Alterations in Leptin Signaling in Amyotrophic Lateral Sclerosis (ALS).

Ferrer-Donato A, Contreras A, Frago LM, Chowen JA, Fernandez-Martos CM
International journal of molecular sciences 2021 Sep 24;22(19)

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Leptin Modulates the Response of Brown Adipose Tissue to Negative Energy Balance: Implication of the GH/IGF-I Axis.

Barrios V, Frago LM, Canelles S, Guerra-Cantera S, Arilla-Ferreiro E, Chowen JA, Argente J
International journal of molecular sciences 2021 Mar 11;22(6)

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Phosphorylated nuclear factor erythroid 2-related factor 2 promotes the secretion of C-C motif chemokine ligand 2 and the recruitment of M2 macrophages.

Huang Z, Li X, Zhou T, Jiang Y, Shi JH
Annals of translational medicine 2021 Dec;9(23):1719