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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [32]
- Comments [0]
- Validations [0]
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- Product number
- 66739-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- ARL13B antibody
- Antibody type
- Monoclonal
- Description
- ARL13B antibody (Cat. #66739-1-Ig) is a mouse monoclonal antibody that shows reactivity with Canine, Human, mouse, pig and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human, Mouse, Canine, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1H6C3
- Vial size
- 20ul, 150ul
Submitted references Lysine attenuates acute lung injury by restoring α-tubulin acetylation and ciliary activity.
Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells.
Enhanced release of ciliary extracellular vesicles suppresses cell migration and promotes cell aggregation.
The BBS/CCT chaperonin complex ensures the localization of the adhesion G protein-coupled receptor ADGRV1 to the base of primary cilia.
Cholangiocytes' primary cilia regulate DNA damage response and repair.
CEP76 impairment at the centrosome-cilium interface contributes to a spectrum of ciliopathies.
A conserved mechanism for the retrieval of polyubiquitinated proteins from cilia.
Merlin controls limb development and thumb formation by regulating primary cilium-hedgehog signaling.
Golgi-localized phosphatidylinositol 4-kinase β mediates Rab11a activation and trafficking to promote ciliogenesis.
PAK6 rescues pathogenic LRRK2-mediated ciliogenesis and centrosomal cohesion defects in a mutation-specific manner.
Linkage between Fuz and Gpr161 genes regulates sonic hedgehog signaling during mouse neural tube development.
Selective targeting of mu opioid receptors to primary cilia.
Bridge-like lipid transfer protein family member 2 suppresses ciliogenesis.
Basis of gene-specific transcription regulation by the Integrator complex.
TTBK2 (T3290C) mutation in spinocerebellar ataxia 11 interferes with ciliogenesis.
Primary cilia abnormalities participate in the occurrence of spontaneous abortion through TGF-β/SMAD2/3 signaling pathway.
A neurodevelopmental disorder associated with a loss-of-function missense mutation in RAB35.
EVC-EVC2 complex stability and ciliary targeting are regulated by modification with ubiquitin and SUMO.
Regulation of Primary Cilium Length by O-GlcNAc during Neuronal Development in a Human Neuron Model.
Disease-associated mutations in WDR34 lead to diverse impacts on the assembly and function of dynein-2.
XBP1 Activation Reduces Severity of Polycystic Kidney Disease due to a Nontruncating Polycystin-1 Mutation in Mice.
The AMPK-Sirtuin 1-YAP axis is regulated by fluid flow intensity and controls autophagy flux in kidney epithelial cells.
Multiple ciliary localization signals control INPP5E ciliary targeting.
INTS13 variants causing a recessive developmental ciliopathy disrupt assembly of the Integrator complex.
Stromal cells of giant cell tumor of bone show primary cilia in giant cell tumor of bone.
The Male Mouse Meiotic Cilium Emanates from the Mother Centriole at Zygotene Prior to Centrosome Duplication.
HTR6 and SSTR3 ciliary targeting relies on both IC3 loops and C-terminal tails.
CCP1, a Tubulin Deglutamylase, Increases Survival of Rodent Spinal Cord Neurons following Glutamate-Induced Excitotoxicity.
The autophagy protein ATG16L1 cooperates with IFT20 and INPP5E to regulate the turnover of phosphoinositides at the primary cilium.
Embryonic and foetal expression patterns of the ciliopathy gene CEP164.
Use of patient derived urine renal epithelial cells to confirm pathogenicity of PKHD1 alleles.
Targeted exon skipping rescues ciliary protein composition defects in Joubert syndrome patient fibroblasts.
Yang W, Meng X, Zhu Y, Ma X, Cao Z, Wang M, Dai W, Tao Y, Jian X, Tian R, Yang Z, Wang R
Cell death discovery 2026 Mar 16;12(1)
Cell death discovery 2026 Mar 16;12(1)
Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells.
Jin L, Wei L, Hua J, Zhang R, Chen J, He J, Yang Y
Oncology reports 2026 Feb;55(2)
Oncology reports 2026 Feb;55(2)
Enhanced release of ciliary extracellular vesicles suppresses cell migration and promotes cell aggregation.
Hara T, Nakazato R, Shirakawa K, Ijaz F, Uemura K, Takahashi S, Ikegami K
Cell structure and function 2026 Feb 20;51(1):67-79
Cell structure and function 2026 Feb 20;51(1):67-79
The BBS/CCT chaperonin complex ensures the localization of the adhesion G protein-coupled receptor ADGRV1 to the base of primary cilia.
Linnert J, Kusuluri DK, Güler BE, Patnaik SR, May-Simera HL, Wolfrum U
Frontiers in cell and developmental biology 2025;13:1520723
Frontiers in cell and developmental biology 2025;13:1520723
Cholangiocytes' primary cilia regulate DNA damage response and repair.
Peixoto E, Pant K, Richard S, Popoca JP, Abrahante JE, Czaja W, Gradilone SA
American journal of physiology. Gastrointestinal and liver physiology 2025 Sep 1;329(3):G469-G483
American journal of physiology. Gastrointestinal and liver physiology 2025 Sep 1;329(3):G469-G483
CEP76 impairment at the centrosome-cilium interface contributes to a spectrum of ciliopathies.
Khan K, Tavares E, Bishara K, Ozanturk A, Qebibo L, Frangakis S, Calame DG, Meunier I, Bocquet B, Ploski R, Al Khateeb MA, Marafi D, Mansard L, Damaj L, Lewis RA, Ullah F, Arbogast T, Ogden JP, Harion M, Willems M, Zaki MS, Bartolomaeus T, Roux AF, Lupski JR, Rydzanicz M, Jamra RA, Ramond F, Heon E, Burglen L, Davis EE
Science advances 2025 Oct 17;11(42):eadw3717
Science advances 2025 Oct 17;11(42):eadw3717
A conserved mechanism for the retrieval of polyubiquitinated proteins from cilia.
Lange SM, Bennett JA, Eisert RJ, Brown A
Cell 2025 Nov 13;188(23):6492-6508.e18
Cell 2025 Nov 13;188(23):6492-6508.e18
Merlin controls limb development and thumb formation by regulating primary cilium-hedgehog signaling.
Wu S, Bian Y, Zhang C, Liu K, Sun F, Chen E, Zhou C, Yu L, Chen G, Wu M
Cell reports 2025 Jun 24;44(6):115849
Cell reports 2025 Jun 24;44(6):115849
Golgi-localized phosphatidylinositol 4-kinase β mediates Rab11a activation and trafficking to promote ciliogenesis.
Wang L, Sun J, Sun S, Huang Z, Liu Y, Yan S, Sun C, Feng Q, Fu W, Zhong T, Zhang J, Zhou J, Liu P
Science advances 2025 Dec 5;11(49):eadw6910
Science advances 2025 Dec 5;11(49):eadw6910
PAK6 rescues pathogenic LRRK2-mediated ciliogenesis and centrosomal cohesion defects in a mutation-specific manner.
Iannotta L, Fasiczka R, Favetta G, Zhao Y, Giusto E, Dall'Ara E, Wei J, Ho FY, Ciriani C, Cogo S, Tessari I, Iaccarino C, Liberelle M, Bubacco L, Taymans JM, Manzoni C, Kortholt A, Civiero L, Hilfiker S, Lu ML, Greggio E
Cell death & disease 2024 Oct 17;15(10):752
Cell death & disease 2024 Oct 17;15(10):752
Linkage between Fuz and Gpr161 genes regulates sonic hedgehog signaling during mouse neural tube development.
Kim SE, Kim HY, Wlodarczyk BJ, Finnell RH
Development (Cambridge, England) 2024 Oct 1;151(19)
Development (Cambridge, England) 2024 Oct 1;151(19)
Selective targeting of mu opioid receptors to primary cilia.
Fagan RR, Lee DF, Geron M, Scherrer G, von Zastrow M, Ehrlich AT
Cell reports 2024 May 28;43(5):114164
Cell reports 2024 May 28;43(5):114164
Bridge-like lipid transfer protein family member 2 suppresses ciliogenesis.
Parolek J, Burd CG
Molecular biology of the cell 2024 May 1;35(5):br11
Molecular biology of the cell 2024 May 1;35(5):br11
Basis of gene-specific transcription regulation by the Integrator complex.
Sabath K, Nabih A, Arnold C, Moussa R, Domjan D, Zaugg JB, Jonas S
Molecular cell 2024 Jul 11;84(13):2525-2541.e12
Molecular cell 2024 Jul 11;84(13):2525-2541.e12
TTBK2 (T3290C) mutation in spinocerebellar ataxia 11 interferes with ciliogenesis.
Luo R, Zeng X, Li P, Hu S, Qi X
Translational neuroscience 2024 Jan 1;15(1):20220353
Translational neuroscience 2024 Jan 1;15(1):20220353
Primary cilia abnormalities participate in the occurrence of spontaneous abortion through TGF-β/SMAD2/3 signaling pathway.
Yu X, Li L, Ning A, Wang H, Guan C, Ma X, Xia H
Journal of cellular physiology 2024 Aug;239(8):e31292
Journal of cellular physiology 2024 Aug;239(8):e31292
A neurodevelopmental disorder associated with a loss-of-function missense mutation in RAB35.
Aguila A, Salah S, Kulasekaran G, Shweiki M, Shaul-Lotan N, Mor-Shaked H, Daana M, Harel T, McPherson PS
The Journal of biological chemistry 2024 Apr;300(4):107124
The Journal of biological chemistry 2024 Apr;300(4):107124
EVC-EVC2 complex stability and ciliary targeting are regulated by modification with ubiquitin and SUMO.
Barbeito P, Martin-Morales R, Palencia-Campos A, Cerrolaza J, Rivas-Santos C, Gallego-Colastra L, Caparros-Martin JA, Martin-Bravo C, Martin-Hurtado A, Sánchez-Bellver L, Marfany G, Ruiz-Perez VL, Garcia-Gonzalo FR
Frontiers in cell and developmental biology 2023;11:1190258
Frontiers in cell and developmental biology 2023;11:1190258
Regulation of Primary Cilium Length by O-GlcNAc during Neuronal Development in a Human Neuron Model.
Tian JL, Huang CW, Eslami F, Mannino MP, Mai RL, Hart GW
Cells 2023 May 31;12(11)
Cells 2023 May 31;12(11)
Disease-associated mutations in WDR34 lead to diverse impacts on the assembly and function of dynein-2.
Shak C, Vuolo L, Uddin B, Katoh Y, Brown T, Mukhopadhyay AG, Heesom K, Roberts AJ, Stevenson N, Nakayama K, Stephens DJ
Journal of cell science 2023 Mar 1;136(5)
Journal of cell science 2023 Mar 1;136(5)
XBP1 Activation Reduces Severity of Polycystic Kidney Disease due to a Nontruncating Polycystin-1 Mutation in Mice.
Krappitz M, Bhardwaj R, Dong K, Staudner T, Yilmaz DE, Pioppini C, Westergerling P, Ruemmele D, Hollmann T, Nguyen TA, Cai Y, Gallagher AR, Somlo S, Fedeles S
Journal of the American Society of Nephrology : JASN 2023 Jan 1;34(1):110-121
Journal of the American Society of Nephrology : JASN 2023 Jan 1;34(1):110-121
The AMPK-Sirtuin 1-YAP axis is regulated by fluid flow intensity and controls autophagy flux in kidney epithelial cells.
Claude-Taupin A, Isnard P, Bagattin A, Kuperwasser N, Roccio F, Ruscica B, Goudin N, Garfa-Traoré M, Regnier A, Turinsky L, Burtin M, Foretz M, Pontoglio M, Morel E, Viollet B, Terzi F, Codogno P, Dupont N
Nature communications 2023 Dec 5;14(1):8056
Nature communications 2023 Dec 5;14(1):8056
Multiple ciliary localization signals control INPP5E ciliary targeting.
Cilleros-Rodriguez D, Martin-Morales R, Barbeito P, Deb Roy A, Loukil A, Sierra-Rodero B, Herranz G, Pampliega O, Redrejo-Rodriguez M, Goetz SC, Izquierdo M, Inoue T, Garcia-Gonzalo FR
eLife 2022 Sep 5;11
eLife 2022 Sep 5;11
INTS13 variants causing a recessive developmental ciliopathy disrupt assembly of the Integrator complex.
Mascibroda LG, Shboul M, Elrod ND, Colleaux L, Hamamy H, Huang KL, Peart N, Singh MK, Lee H, Merriman B, Jodoin JN, Sitaram P, Lee LA, Fathalla R, Al-Rawashdeh B, Ababneh O, El-Khateeb M, Escande-Beillard N, Nelson SF, Wu Y, Tong L, Kenney LJ, Roy S, Russell WK, Amiel J, Reversade B, Wagner EJ
Nature communications 2022 Oct 13;13(1):6054
Nature communications 2022 Oct 13;13(1):6054
Stromal cells of giant cell tumor of bone show primary cilia in giant cell tumor of bone.
Castiella T, Iruzubieta P, Monleón E, Cardiel MJ, Gómez-Vallejo J, Monzón M, Junquera MC
Microscopy research and technique 2022 Mar;85(3):1065-1074
Microscopy research and technique 2022 Mar;85(3):1065-1074
The Male Mouse Meiotic Cilium Emanates from the Mother Centriole at Zygotene Prior to Centrosome Duplication.
López-Jiménez P, Pérez-Martín S, Hidalgo I, García-Gonzalo FR, Page J, Gómez R
Cells 2022 Dec 29;12(1)
Cells 2022 Dec 29;12(1)
HTR6 and SSTR3 ciliary targeting relies on both IC3 loops and C-terminal tails.
Barbeito P, Tachibana Y, Martin-Morales R, Moreno P, Mykytyn K, Kobayashi T, Garcia-Gonzalo FR
Life science alliance 2021 Mar;4(3)
Life science alliance 2021 Mar;4(3)
CCP1, a Tubulin Deglutamylase, Increases Survival of Rodent Spinal Cord Neurons following Glutamate-Induced Excitotoxicity.
Ramadan YH, Gu A, Ross N, McEwan SA, Barr MM, Firestein BL, O'Hagan R
eNeuro 2021 Mar-Apr;8(2)
eNeuro 2021 Mar-Apr;8(2)
The autophagy protein ATG16L1 cooperates with IFT20 and INPP5E to regulate the turnover of phosphoinositides at the primary cilium.
Boukhalfa A, Roccio F, Dupont N, Codogno P, Morel E
Cell reports 2021 Apr 27;35(4):109045
Cell reports 2021 Apr 27;35(4):109045
Embryonic and foetal expression patterns of the ciliopathy gene CEP164.
Devlin LA, Ramsbottom SA, Overman LM, Lisgo SN, Clowry G, Molinari E, Powell L, Miles CG, Sayer JA
PloS one 2020;15(1):e0221914
PloS one 2020;15(1):e0221914
Use of patient derived urine renal epithelial cells to confirm pathogenicity of PKHD1 alleles.
Molinari E, Srivastava S, Dewhurst RM, Sayer JA
BMC nephrology 2020 Oct 15;21(1):435
BMC nephrology 2020 Oct 15;21(1):435
Targeted exon skipping rescues ciliary protein composition defects in Joubert syndrome patient fibroblasts.
Molinari E, Ramsbottom SA, Srivastava S, Booth P, Alkanderi S, McLafferty SM, Devlin LA, White K, Gunay-Aygun M, Miles CG, Sayer JA
Scientific reports 2019 Jul 25;9(1):10828
Scientific reports 2019 Jul 25;9(1):10828
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