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- Product number
- 17988-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17988-1-AP, RRID:AB_2178441
- Product name
- REEP1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated REEP1 antibody (Cat. #17988-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Multi-omics mapping identifies CYBA-mediated mitochondrial dysfunction driving macrophage polarization and ferroptosis via Nrf2 pathway in atherosclerosis.
REEP1 Accumulation Disrupts ER Integrity and Drives Spinal Motoneuron Degeneration in Distal Hereditary Motor Neuropathy.
Altered tRNA expression profile associated with codon-specific proteomic changes in the suicide brain.
Phillyrin promotes autophagosome formation in A53T-αSyn-induced Parkinson's disease model via modulation of REEP1.
Aurora kinase A-mediated phosphorylation triggers structural alteration of Rab1A to enhance ER complexity during mitosis.
Fam134c and Fam134b shape axonal endoplasmic reticulum architecture in vivo.
Heteromeric clusters of ubiquitinated ER-shaping proteins drive ER-phagy.
Transverse endoplasmic reticulum expansion in hereditary spastic paraplegia corticospinal axons.
Disease-causing mutated ATLASTIN 3 is excluded from distal axons and reduces axonal autophagy.
DIPK2A promotes STX17- and VAMP7-mediated autophagosome-lysosome fusion by binding to VAMP7B.
DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.
Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.
Reep1 null mice reveal a converging role for hereditary spastic paraplegia proteins in lipid droplet regulation.
Dong C, Shen R, Pan C, Zhang J, Yu K, Zeng Q
APL bioengineering 2026 Mar;10(1):016107
APL bioengineering 2026 Mar;10(1):016107
REEP1 Accumulation Disrupts ER Integrity and Drives Spinal Motoneuron Degeneration in Distal Hereditary Motor Neuropathy.
Bock A, Schurig M, Willoughby M, Mirecki A, Seemann E, Lohachova K, Katona I, Mittag S, Liebmann L, Franzka P, Heidari Horestani M, Khundadze M, Mosler T, Louie T, de Visser M, Weterman MAJ, Kiehntopf M, Beetz C, Nietzsche S, Huber O, Weis J, Kessels MM, Bhaskara RM, Qualmann B, Đikić I, Hübner CA
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(2):e11483
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(2):e11483
Altered tRNA expression profile associated with codon-specific proteomic changes in the suicide brain.
Blaze J, Chen S, Heissel S, Alwaseem H, Landinez Macias MP, Peter C, Molina H, Storkebaum E, Turecki G, Goodarzi H, Akbarian S
Molecular psychiatry 2025 Jul;30(7):2871-2879
Molecular psychiatry 2025 Jul;30(7):2871-2879
Phillyrin promotes autophagosome formation in A53T-αSyn-induced Parkinson's disease model via modulation of REEP1.
Qi LF, Liu Y, Liu S, Xiang L, Liu Z, Liu Q, Zhao JQ, Xu X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155952
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155952
Aurora kinase A-mediated phosphorylation triggers structural alteration of Rab1A to enhance ER complexity during mitosis.
Zhang W, Zhang Z, Xiang Y, Gu DD, Chen J, Chen Y, Zhai S, Liu Y, Jiang T, Liu C, He B, Yan M, Wang Z, Xu J, Cao YL, Deng B, Zeng D, Lei J, Zhuo J, Lei X, Long Z, Jin B, Chen T, Li D, Shen Y, Hu J, Gao S, Liu Q
Nature structural & molecular biology 2024 Feb;31(2):219-231
Nature structural & molecular biology 2024 Feb;31(2):219-231
Fam134c and Fam134b shape axonal endoplasmic reticulum architecture in vivo.
Iavarone F, Zaninello M, Perrone M, Monaco M, Barth E, Gaedke F, Pizzo MT, Di Lorenzo G, Desiderio V, Sommella E, Merciai F, Salviati E, Campiglia P, Luongo L, De Leonibus E, Rugarli E, Settembre C
EMBO reports 2024 Aug;25(8):3651-3677
EMBO reports 2024 Aug;25(8):3651-3677
Heteromeric clusters of ubiquitinated ER-shaping proteins drive ER-phagy.
Foronda H, Fu Y, Covarrubias-Pinto A, Bocker HT, González A, Seemann E, Franzka P, Bock A, Bhaskara RM, Liebmann L, Hoffmann ME, Katona I, Koch N, Weis J, Kurth I, Gleeson JG, Reggiori F, Hummer G, Kessels MM, Qualmann B, Mari M, Dikić I, Hübner CA
Nature 2023 Jun;618(7964):402-410
Nature 2023 Jun;618(7964):402-410
Transverse endoplasmic reticulum expansion in hereditary spastic paraplegia corticospinal axons.
Zhu PP, Hung HF, Batchenkova N, Nixon-Abell J, Henderson J, Zheng P, Renvoisé B, Pang S, Xu CS, Saalfeld S, Funke J, Xie Y, Svara F, Hess HF, Blackstone C
Human molecular genetics 2022 Aug 23;31(16):2779-2795
Human molecular genetics 2022 Aug 23;31(16):2779-2795
Disease-causing mutated ATLASTIN 3 is excluded from distal axons and reduces axonal autophagy.
Behrendt L, Hoischen C, Kaether C
Neurobiology of disease 2021 Jul;155:105400
Neurobiology of disease 2021 Jul;155:105400
DIPK2A promotes STX17- and VAMP7-mediated autophagosome-lysosome fusion by binding to VAMP7B.
Tian X, Zheng P, Zhou C, Wang X, Ma H, Ma W, Zhou X, Teng J, Chen J
Autophagy 2020 May;16(5):797-810
Autophagy 2020 May;16(5):797-810
DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.
Zheng P, Chen Q, Tian X, Qian N, Chai P, Liu B, Hu J, Blackstone C, Zhu D, Teng J, Chen J
Cell research 2018 Aug;28(8):833-854
Cell research 2018 Aug;28(8):833-854
Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease.
Sharoar MG, Shi Q, Ge Y, He W, Hu X, Perry G, Zhu X, Yan R
Molecular psychiatry 2016 Sep;21(9):1263-71
Molecular psychiatry 2016 Sep;21(9):1263-71
Reep1 null mice reveal a converging role for hereditary spastic paraplegia proteins in lipid droplet regulation.
Renvoisé B, Malone B, Falgairolle M, Munasinghe J, Stadler J, Sibilla C, Park SH, Blackstone C
Human molecular genetics 2016 Dec 1;25(23):5111-5125
Human molecular genetics 2016 Dec 1;25(23):5111-5125
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The REEP1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human REEP1. This antibody recognizes human,mouse,rat antigen. The REEP1 antibody has been validated for the following applications: ELISA, WB analysis.
