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- References [18]
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- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 16178-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16178-1-AP, RRID:AB_2135051
- Product name
- Lin28B-specific antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Lin28B-specific antibody (Cat. #16178-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references RNA m(5)C modification upregulates E2F1 expression in a manner dependent on YBX1 phase separation and promotes tumor progression in ovarian cancer.
LOC101929709 promotes gastric cancer progression by aiding LIN28B to stabilize c-MYC mRNA.
Sirt6 inhibits vascular endothelial cell pyroptosis by regulation of the Lin28b/let-7 pathway in atherosclerosis.
Long Non-Coding RNA LINC00467 Correlates to Poor Prognosis and Aggressiveness of Breast Cancer.
Lin 28A/Occludin axis: An aberrantly activated pathway in intestinal epithelial cells leading to impaired barrier function under total parenteral nutrition.
LIN28B Underlies the Pathogenesis of a Subclass of Ewing Sarcoma LIN28B Control of EWS-FLI1 Stability.
LIN28B Underlies the Pathogenesis of a Subclass of Ewing Sarcoma.
Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1.
Cellular 5-hydroxylmethylcytosine content determines tumorigenic potential and prognosis of pancreatic ductal adenocarcinoma.
Exosomes Serve as Nanoparticles to Deliver Anti-miR-214 to Reverse Chemoresistance to Cisplatin in Gastric Cancer.
Different expression patterns of Lin28 and Lin28b in mouse molar development.
Expression and associations of TRAF1, BMI-1, ALDH1, and Lin28B in oral squamous cell carcinoma.
Activation of the Lin28/let-7 Axis by Loss of ESE3/EHF Promotes a Tumorigenic and Stem-like Phenotype in Prostate Cancer.
JMJD1A promotes tumorigenesis and forms a feedback loop with EZH2/let-7c in NSCLC cells.
Testicular expression of the Lin28/let-7 system: Hormonal regulation and changes during postnatal maturation and after manipulations of puberty.
Unique haploinsufficient role of the microRNA-processing molecule Dicer1 in a murine colitis-associated tumorigenesis model.
Increased expression of Lin28B associates with poor prognosis in patients with oral squamous cell carcinoma.
Distinct expression patterns predict differential roles of the miRNA-binding proteins, Lin28 and Lin28b, in the mouse testis: studies during postnatal development and in a model of hypogonadotropic hypogonadism.
Liu X, Wei Q, Yang C, Zhao H, Xu J, Mobet Y, Luo Q, Yang D, Zuo X, Chen N, Yang Y, Li L, Wang W, Yu J, Xu J, Liu T, Yi P
Experimental & molecular medicine 2024 Mar;56(3):600-615
Experimental & molecular medicine 2024 Mar;56(3):600-615
LOC101929709 promotes gastric cancer progression by aiding LIN28B to stabilize c-MYC mRNA.
Xu TP, Yu T, Xie MY, Fang Y, Xu TT, Pan YT, Ma P, Shu YQ
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2023 Mar;26(2):169-186
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2023 Mar;26(2):169-186
Sirt6 inhibits vascular endothelial cell pyroptosis by regulation of the Lin28b/let-7 pathway in atherosclerosis.
Yao F, Lv X, Jin Z, Chen D, Zheng Z, Yang J, Ren L, Wang B, Wang W, He J, Song Q, Gu J, Lin R
International immunopharmacology 2022 Sep;110:109056
International immunopharmacology 2022 Sep;110:109056
Long Non-Coding RNA LINC00467 Correlates to Poor Prognosis and Aggressiveness of Breast Cancer.
Zhang Y, Sun Y, Ding L, Shi W, Ding K, Zhu Y
Frontiers in oncology 2021;11:643394
Frontiers in oncology 2021;11:643394
Lin 28A/Occludin axis: An aberrantly activated pathway in intestinal epithelial cells leading to impaired barrier function under total parenteral nutrition.
Liu Y, Gong Z, Zhou J, Yan J, Cai W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21189
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21189
LIN28B Underlies the Pathogenesis of a Subclass of Ewing Sarcoma LIN28B Control of EWS-FLI1 Stability.
Keskin T, Bakaric A, Waszyk P, Boulay G, Torsello M, Cornaz-Buros S, Chevalier N, Geiser T, Martin P, Volorio A, Iyer S, Kulkarni A, Letovanec I, Cherix S, Cote GM, Choy E, Digklia A, Montemurro M, Chebib I, Nielsen PG, Carcaboso AM, Mora J, Renella R, Suvà ML, Fusco C, Provero P, Rivera MN, Riggi N, Stamenkovic I
Cell reports 2020 Mar 31;30(13):4567-4583.e5
Cell reports 2020 Mar 31;30(13):4567-4583.e5
LIN28B Underlies the Pathogenesis of a Subclass of Ewing Sarcoma.
Keskin T, Bakaric A, Waszyk P, Boulay G, Torsello M, Cornaz-Buros S, Chevalier N, Geiser T, Martin P, Volorio A, Iyer S, Kulkarni A, Letovanec I, Cherix S, Cote GM, Choy E, Digklia A, Montemurro M, Chebib I, Nielsen PG, Carcaboso AM, Mora J, Renella R, Suvà ML, Fusco C, Provero P, Rivera MN, Riggi N, Stamenkovic I
Cell reports 2020 Apr 14;31(2):107539
Cell reports 2020 Apr 14;31(2):107539
Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1.
Zhang Y, Li C, Hu C, Wu Q, Cai Y, Xing S, Lu H, Wang L, Huang D, Sun L, Li T, He X, Zhong X, Wang J, Gao P, Smith ZJ, Jia W, Zhang H
EMBO reports 2019 Oct 4;20(10):e48115
EMBO reports 2019 Oct 4;20(10):e48115
Cellular 5-hydroxylmethylcytosine content determines tumorigenic potential and prognosis of pancreatic ductal adenocarcinoma.
Chen YL, Hu CM, Hsu JT, Chang CC, Huang TY, Chiang PH, Chen WY, Chang YT, Chang MC, Tien YW, Lee EY, Jeng YM, Lee WH
American journal of cancer research 2018;8(12):2548-2563
American journal of cancer research 2018;8(12):2548-2563
Exosomes Serve as Nanoparticles to Deliver Anti-miR-214 to Reverse Chemoresistance to Cisplatin in Gastric Cancer.
Wang X, Zhang H, Bai M, Ning T, Ge S, Deng T, Liu R, Zhang L, Ying G, Ba Y
Molecular therapy : the journal of the American Society of Gene Therapy 2018 Mar 7;26(3):774-783
Molecular therapy : the journal of the American Society of Gene Therapy 2018 Mar 7;26(3):774-783
Different expression patterns of Lin28 and Lin28b in mouse molar development.
Dong N, Liu Y, Zhang T, Zhao L, Tian J, Ruan J
Archives of oral biology 2017 Oct;82:280-285
Archives of oral biology 2017 Oct;82:280-285
Expression and associations of TRAF1, BMI-1, ALDH1, and Lin28B in oral squamous cell carcinoma.
Wu TF, Li YC, Ma SR, Bing-Liu, Zhang WF, Sun ZJ
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Apr;39(4):1010428317695930
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Apr;39(4):1010428317695930
Activation of the Lin28/let-7 Axis by Loss of ESE3/EHF Promotes a Tumorigenic and Stem-like Phenotype in Prostate Cancer.
Albino D, Civenni G, Dallavalle C, Roos M, Jahns H, Curti L, Rossi S, Pinton S, D'Ambrosio G, Sessa F, Hall J, Catapano CV, Carbone GM
Cancer research 2016 Jun 15;76(12):3629-43
Cancer research 2016 Jun 15;76(12):3629-43
JMJD1A promotes tumorigenesis and forms a feedback loop with EZH2/let-7c in NSCLC cells.
Zhan M, Wen F, Liu L, Chen Z, Wei H, Zhou H
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Aug;37(8):11237-47
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Aug;37(8):11237-47
Testicular expression of the Lin28/let-7 system: Hormonal regulation and changes during postnatal maturation and after manipulations of puberty.
Sangiao-Alvarellos S, Manfredi-Lozano M, Ruiz-Pino F, León S, Morales C, Cordido F, Gaytán F, Pinilla L, Tena-Sempere M
Scientific reports 2015 Oct 23;5:15683
Scientific reports 2015 Oct 23;5:15683
Unique haploinsufficient role of the microRNA-processing molecule Dicer1 in a murine colitis-associated tumorigenesis model.
Yoshikawa T, Otsuka M, Kishikawa T, Takata A, Ohno M, Shibata C, Kang YJ, Yoshida H, Koike K
PloS one 2013;8(9):e71969
PloS one 2013;8(9):e71969
Increased expression of Lin28B associates with poor prognosis in patients with oral squamous cell carcinoma.
Wu T, Jia J, Xiong X, He H, Bu L, Zhao Z, Huang C, Zhang W
PloS one 2013;8(12):e83869
PloS one 2013;8(12):e83869
Distinct expression patterns predict differential roles of the miRNA-binding proteins, Lin28 and Lin28b, in the mouse testis: studies during postnatal development and in a model of hypogonadotropic hypogonadism.
Gaytan F, Sangiao-Alvarellos S, Manfredi-Lozano M, García-Galiano D, Ruiz-Pino F, Romero-Ruiz A, León S, Morales C, Cordido F, Pinilla L, Tena-Sempere M
Endocrinology 2013 Mar;154(3):1321-36
Endocrinology 2013 Mar;154(3):1321-36
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Lin28B-specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human Lin28B-specific. This antibody recognizes human, mouse antigen. The Lin28B-specific antibody has been validated for the following applications: ELISA, IHC, IF analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 16178-1-AP(Lin28B-specific antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 16178-1-AP(Lin28B-specific antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
