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- Product number
- AF4308 - Provider product page
- Provider
- R&D Systems
- Product name
- Human Prolyl Oligopeptidase/PREP Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human PREP in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant mouse PREP is observed.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Antigen sequence
P48147- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Prolyl oligopeptidase enhances α-synuclein dimerization via direct protein-protein interaction.
The prolyl peptidases PRCP/PREP regulate IRS-1 stability critical for rapamycin-induced feedback activation of PI3K and AKT.
Savolainen MH, Yan X, Myöhänen TT, Huttunen HJ
The Journal of biological chemistry 2015 Feb 20;290(8):5117-26
The Journal of biological chemistry 2015 Feb 20;290(8):5117-26
The prolyl peptidases PRCP/PREP regulate IRS-1 stability critical for rapamycin-induced feedback activation of PI3K and AKT.
Duan L, Ying G, Danzer B, Perez RE, Shariat-Madar Z, Levenson VV, Maki CG
The Journal of biological chemistry 2014 Aug 1;289(31):21694-705
The Journal of biological chemistry 2014 Aug 1;289(31):21694-705
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