TIMM8B

This gene encodes a member of a well-conserved family of proteins with similarity to yeast Tim mitochondrial import proteins. This gene is encoded by a nuclear gene and is transported into the intermembrane space of the mitochondrion. When formed into complexes, these proteins guide membrane-spanning proteins across the mitochondrial intermembrane space before they are added into the mitochondrial inner membrane. This gene is adjacent to succinate dehydrogenase, subunit D (SDHD), in which mutations have been found in affected members of families with hereditary paraganglioma. [provided by RefSeq, Aug 2009]

Description

Translocase of inner mitochondrial membrane 8 homolog B

Tissue specificity

Low tissue specificity

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)

Chromosome

11 (112084800 - 112086798)

Ensembl ID

ENSG00000150779  (ver. 103.38)

Orthologs

Mouse Timm8b: ENSMUSG00000039016

UniProt

Q9Y5J9

neXtProt

NX_Q9Y5J9

Human splice variants
Mouse splice variants

Protein structure