FNab00221

antibody from FineTest Biotech
Targeting: GPSM1 AGS3, DKFZP727I051
Provider product page for FNab00221
Western blot
ELISA
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
FNab00221 - Provider product page
Provider
FineTest Biotech
Product name
AGS3 antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
GPSM1, also named as AGS3, is a receptor-independent G protein activator that has been implicated in multiple biological events such as brain development, neuroplasticity and addiction, cardiac function, Golgi structure/function, macroautophagy and metabolism. It contains seven tetratricopeptide repeats in its N-terminal half and four G-protein regulatory(GPR) motifs in its C-terminal half. It has been shown that AGS3 could regulate the orientation of the mitotic spindle, cAMP production, membrane protein transport, and asymmetric cell division by binding preferentially to inactive Gai/o subunits complexed with guanine dinucleotide phosphate(GDP) at multiple G-protein regulatory or GoLoco motif repeats. It also plays an important anti-apoptotic role through enhancing the phosphorylation of cyclic AMP response element-binding protein(p-CREB).
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
G-protein signaling modulator 1(AGS
3-like, C. elegans)
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
GPSM1 protein structure - FNab00221 shown in red.