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- Antigen structure
- References [4]
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- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- ABIN1449927 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein (SDHD) (Middle Region) antibody
- Antibody type
- Polyclonal
- Antigen
- 15 amino acid synthetic peptide near the center of Human SDHD
- Description
- Affinity chromatography purified via peptide column
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- Middle Region
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references The R22X mutation of the SDHD gene in hereditary paraganglioma abolishes the enzymatic activity of complex II in the mitochondrial respiratory chain and activates the hypoxia pathway.
Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma.
Oxidative phosphorylation at the fin de siècle.
Genetics of human cancer.
Gimenez-Roqueplo AP, Favier J, Rustin P, Mourad JJ, Plouin PF, Corvol P, Rötig A, Jeunemaitre X
American journal of human genetics 2001 Dec;69(6):1186-97
American journal of human genetics 2001 Dec;69(6):1186-97
Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma.
Baysal BE, Ferrell RE, Willett-Brozick JE, Lawrence EC, Myssiorek D, Bosch A, van der Mey A, Taschner PE, Rubinstein WS, Myers EN, Richard CW 3rd, Cornelisse CJ, Devilee P, Devlin B
Science (New York, N.Y.) 2000 Feb 4;287(5454):848-51
Science (New York, N.Y.) 2000 Feb 4;287(5454):848-51
Oxidative phosphorylation at the fin de siècle.
Saraste M
Science (New York, N.Y.) 1999 Mar 5;283(5407):1488-93
Science (New York, N.Y.) 1999 Mar 5;283(5407):1488-93
Genetics of human cancer.
Knudson AG Jr
Annual review of genetics 1986;20:231-51
Annual review of genetics 1986;20:231-51
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of SDHD in EL4 cell lysate with SDHD antibody at (A) 1 and (B) 2 ug/mL.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunocytochemistry of SDHD in EL4 cells with SDHD antibody at 2.5 ug/mL.
