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- References [445]
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- Product number
- 10181-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10181-2-AP, RRID:AB_2062045
- Product name
- ATG5 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ATG5 antibody (Cat. #10181-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references NEDD4 promotes reactive astrogliosis by enhancing K63-linked ubiquitination and inhibiting chaperone-mediated autophagy degradation of YAP1.
RNA-binding motif protein 15 promotes gastric cancer growth and drug resistance via USP10-mediated deubiquitination and stabilization of nuclear NRF2.
Porcine reproductive and respiratory syndrome virus nsp2 protects viral RNA-dependent RNA polymerase from autophagic degradation.
High-fat diet perturbs hepatic lipid metabolism and impairs colonic autophagy to exacerbate experimental colitis.
AMBRA1 enhances Sonic Hedgehog signaling during cerebellar development and in medulloblastoma.
Ixazomib triggers autophagic degradation of MUC5AC/integrin-β4 and inhibits non-small cell lung cancer progression.
Homoharringtonine inhibits growth and migration in non-small cell lung cancer via PDIA4-mediated modulation of autophagy and EMT.
Lactucopicrin promotes the autophagic degradation of MAP2K4/MKK4 by mediating CCDC50 palmitoylation to alleviate osteoarthritis progression.
PSAT1 inhibits mTORC1 activation by preventing Rag heterodimer formation in lung adenocarcinoma.
Nitric Oxide Donor Alleviates Cardiac Arrest Induced Blood Brain Barrier Injury by Inhibiting HMGB1-ATG5 Mediated Endothelial Autophagy.
Neurons with granulovacuolar degeneration bodies are resilient to tau-induced protein synthesis impairment.
Small-molecule enhancement of METTL3 S-palmitoylation as a therapeutic strategy for osteoarthritis.
Buyang Huanwu decoction facilitates the repair of red nucleus neurons subsequent to spinal cord injury in rats via autophagy.
Icariin inhibits autophagy and promotes apoptosis by regulating mitochondrial division in Triple-negative breast cancer.
Licochalcone A promotes autophagy to ameliorate NAFLD by inhibiting the mTOR and regulating ULK1/Beclin1/VPS34 pathway.
Liraglutide Ameliorates Injury-Related Vascular Repair by Activating Autophagy Through Modulation of the PI3K-mTOR Signaling Pathway.
GCN2 activates macrophage autophagy to inhibit NLRP3 inflammasome-mediated acute lung injury.
DNA damage in macrophages drives immune autoreactivity via nuclear antigen presentation.
Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress.
Recruitment of CCR5(+) inflammatory monocytes in pulmonary tissue contributes to acute lung injury.
CPNE3 promotes colorectal cancer progression by regulating KIF4-mediated autophagy.
Disruption of FGL2 induces TFEB-dependent lysosomal degradation of PD-L1 and enhances the efficacy of anti-PD1 therapy in hepatocellular carcinoma.
VDAC1 protein derived from extracellular vesicles promotes paclitaxel resistance in gastric cancer through autophagy and mitophagy.
Therapeutic potential of magnesium diboride nanosheets in PAH-associated right heart failure: Integrated multi-omics analysis reveals ferroptosis suppression via LC3/ATG5/NCOA4/FTH1 pathway.
An oral-gut microbial metabolite links Fusobacterium nucleatum to aggravated myocardial ischemia-reperfusion injury.
Lactylation of histone H3K18 promotes autophagic gene expression to mitigate immunosuppression in sepsis.
Multi-omics analysis investigates the mechanisms of plasticizer-induced male reproductive infertility in Northwest China.
circLOC375190 promotes autophagy through modulation of the mTORC1/TFEB axis in acute ischemic stroke-induced neurological injury.
Upregulation of phosphatase and tensin homolog deleted on chromosome ten inhibits lung cancer cell proliferation by suppressing the oncogene polo-like kinase 1 and inducing autophagy.
TRIM32 promotes neuronal ferroptosis by enhancing K63-linked ubiquitination and subsequent p62-selective autophagic degradation of GPX4.
Suppression of Inflammation by Si Miao San in Experimental Rheumatoid Arthritis Through Modulation of the AKT/ROS/Autophagy Axis.
Paeoniflorin Attenuates Cognitive Dysfunction and Neuroinflammation by Autophagy in Mice with SLE Induced by Imiquimod.
αAsarone alleviates neuronal injury by facilitating autophagy via miR-499-5p/PDCD4/ATG5 signaling pathway in ischemia stroke.
Fenofibrate suppresses Mycoplasma bovis infection via autophagy-mediated cholesterol regulation in bovine mammary epithelial cells and murine mammary tissue.
Comparative hepatoprotective effects of AMK and PAMK via Nrf2 signaling in broiler breeders.
PLEKHF1 Induces Mitochondrial Dysfunction to Inhibit Osteosarcoma Growth and Metastasis.
CDKL3 Targets ATG5 to Exacerbate the Progression of Malignant Melanoma.
Maternal Myo-Inositol Deficiency Involved Autophagy Impairment by PI3K/Akt/mTOR Signaling in Neural Tube Defects During Pregnancy.
Activation of Sig-1R by afobazole attenuates Tollip/HMGB1-mediaded CCN2 autophagic degradation and NETs formation in sunitinib-induced cardiotoxicity in mice: Involvement of IRE 1α/ASK1/JNK/ AP-1 trajectory.
Klebsiella pneumoniae Induces Ferroptosis and Lactation Dysfunction in Bovine Mastitis via NCOA4-Mediated Ferritinophagy.
Nitrate Promotes the Survival of Diabetic Skin Flaps by Enhancing Autophagy Through the AMPK Signaling Pathway.
(Z)-Ligustilide alleviates intervertebral disc degeneration by suppressing nucleus pulposus cell pyroptosis via Atg5/NLRP3 axis.
UBE2D2 promotes gastric cancer progression by inhibiting ferroptosis through autophagy-dependent stabilization of CST1.
Dual roles of CXCR4 (C-X-C motif chemokine receptor 4) in promoting entry of ebolavirus and targeting excessive glycoprotein for reticulophagic degradation to facilitate viral fitness.
Perfluorohexane sulfonate (PFHxS) induces liver cytotoxicity by activating autophagy and endoplasmic reticulum stress-regulated mitochondrial pathway apoptosis.
Yunnan Baiyao regulates Th17/Treg cell homeostasis to inhibit periodontitis through the miR-155-5p/ATG5 pathway.
Decorin Is a Newly Discovered Target of Akkermansia muciniphila in the Treatment of Sepsis-Associated Encephalopathy.
SFTSV induces liver ferroptosis through m6A-related ferritinophagy.
Gambogic acid induces ferroptosis and suppresses colorectal cancer progression by modulating the m6A modification of p62.
The Composite Antiadhesion Barrier Facilitated Fibroblast Autophagy Activation for Tendon Repair.
Mechanisms of Intermittent Theta-Burst Stimulation Upregulates TFEB and Restores Autophagy to Play a Neuroprotective Role in the Acute Phase After Cerebral Ischemia Reperfusion.
Quercetin ameliorates doxorubicin-induced atrial fibrillation via EGFR-mediated restoration of autophagic flux.
Quercetin alleviated cadmium-induced oxidative stress, endoplasmic reticulum stress, and autophagy in chicken kidneys.
TGF-β2 increases eHSP90α secretion via upregulating secretory autophagy pathway.
Regulation of N-degron recognin-mediated autophagy by the SARS-CoV-2 PLpro ubiquitin deconjugase.
Discovery of a potent inhibitor of chaperone-mediated autophagy that targets the HSC70-LAMP2A interaction in non-small cell lung cancer cells.
Deoxynivalenol-induced pyroptosis and autophagy inhibition collectively promote inflammatory injury in the glandular stomach of chicken embryos.
OTULIN orchestrates NCOA4-FTH1 complex to alleviate APAP-induced hepatocyte Ferroptosis.
Tspan9 Exacerbates Cardiac Hypertrophy by Impairing Cardiac Autophagy.
Retroviral foamy virus gag induces parkin-dependent mitophagy.
Accelerated differentiation of photothermal effect-induced mesenchymal stem cells regulated by activating HSP90-autophagy boosts wound repair.
Analysis of the key signaling pathway of baicalin that induces autophagy in papillary thyroid cancer via an optical resonator.
IGF2BP1-HAX-1 positive feedback loop-mediated HAX-1 overexpression blocks autophagic flux and promotes chemoresistance in nasopharyngeal carcinoma.
ATP6AP1 promotes cell proliferation and tamoxifen resistance in luminal breast cancer by inducing autophagy.
Polystyrene microplastics induce hepatic lipid metabolism and energy disorder by upregulating the NR4A1-AMPK signaling pathway.
Dicyclohexyl phthalate derails trophoblast function and lipid metabolism through NDRG1 by targeting PPARα:RXRα.
Redox regulation of TRIM28 facilitates neuronal ferroptosis by promoting SUMOylation and inhibiting OPTN-selective autophagic degradation of ACSL4.
PFOS causes lysosomes-regulated mitochondrial fission through TRPML1-VDAC1 and oligomerization of MCU/ATP5J2.
Ergosterol Protects Canine MDCK Cells from Gentamicin-Induced Damage by Modulating Autophagy and Apoptosis.
NR4A3 suppresses bladder cancer progression by modulating autophagy via the PI3K/AKT/mTOR pathway.
Pomalidomide promotes macrophage control of Mycobacterium tuberculosis via enhancing HDAC6-mediated autophagy.
BNST(GABA) neurons regulate autophagy to alleviate depression with gastric dysfunction symptoms.
Metformin Improves Palmitate-Induced Follicular Granulosa Cell Dysfunction by Activating ULK1-Mediated Autophagy.
Transglutaminase 2 promotes breast cancer cell autophagy by targeting p53/ mTOR axis.
HMBOX1 reverses autophagy mediated 5-fluorouracil resistance through promoting HACE1-induced ubiquitination and degradation of ATG5 in colorectal cancer.
Optimally Aligned Nerve Scaffolds with Sustained Astaxanthin Release Improve the Inflammatory Microenvironment through Mitophagy Activation.
Inhibiting UPF1 methylation enhances tumor immunotherapy sensitivity by reducing nonsense-mediated mRNA decay.
DHX9-mediated epigenetic silencing of BECN1 contributes to impaired autophagy and tumor progression in breast cancer via recruitment of HDAC5.
USP7 promotes PINK1/Parkin-dependent mitophagy to ameliorate cerebral ischemia-reperfusion injury by deubiquitinating and stabilizing SIRT1.
Bioinformatics analysis and preliminary validation of autophagy-related genes in asthma disease.
Inhibition of ACSS2 triggers glycolysis inhibition and nuclear translocation to activate SIRT1/ATG5/ATG2B deacetylation axis, promoting autophagy and reducing malignancy and chemoresistance in ovarian cancer.
Cyclovirobuxine D inhibits triple-negative breast cancer via YAP/TAZ suppression and activation of the FOXO3a/PINK1-Parkin pathway-induced mitophagy.
GYY4137 ameliorates blood brain barrier damage by inhibiting autophagy mediated occludin degradation in cardiac arrest and resuscitation.
The cholesterol metabolite 25-hydroxycholesterol suppresses porcine deltacoronavirus via lipophagy inhibition and mTORC1 modulation.
Targeting p38γ synergistically enhances sorafenib-induced cytotoxicity in hepatocellular carcinoma.
Transforming growth factor-β3/Smad2/Smad3 signaling pathway inhibition and autophagy by the Yunpi-Xiefei-Huatan decoction ameliorated airway inflammation and mucus hypersecretion in asthmatic rats.
Autophagic signatures in peripheral blood mononuclear cells from Parkinson's disease patients.
HIF-1α/BNIP3-Mediated Endoplasmic Reticulum Degradation via Autophagy Protects Against Ischemia Reperfusion-Induced Acute Kidney Injury.
VANGL2 alleviates inflammatory bowel disease by recruiting the ubiquitin ligase MARCH8 to limit NLRP3 inflammasome activation through OPTN-mediated selective autophagy.
MLKL-USP7-UBA52 signaling is indispensable for autophagy in brain through maintaining ubiquitin homeostasis.
PPARβ/δ Activation Improves Corticosterone-Induced Oxidative Stress Damage in Astrocytes by Targeting UBR5/ATM Signaling.
Therapeutic effect of dihydroartemisinin on Alzheimer's disease model mice with senile macular degeneration.
Targeting NLRC5 in cardiomyocytes protects postinfarction cardiac injury by enhancing autophagy flux through the CAVIN1/CAV1 axis.
Urolithin A alleviates NLRP3 inflammasome activation and pyroptosis by promoting microglial mitophagy following spinal cord injury.
p16(INK4a) promoted progress of MCT induced pulmonary hypertension via maintaining redox balance and autophagy pathway.
Apigenin attenuates the atherosclerotic lesions through enhancing selective autophagy/lipophagy and promoting RCT process.
HMGB1 impairs nasal mucosa epithelial barrier function in allergic rhinitis by promoting BECN1-mediating autophagy.
Porcine cGAS-STING signalling induced apoptosis negatively regulates STING downstream IFN response and autophagy via different mechanisms.
Hypoxia-induced secretory autophagy in cancer-associated fibroblasts promotes ECM remodelling through serglycin secretion in oral squamous cell carcinoma.
Sanggenol L Enhances Temozolomide Drug Sensitivity by Inhibiting Mitophagy and Inducing Apoptosis Through the Regulation of the TRIM16-OPTN Axis in Glioblastoma.
Targeting FoxO1-STX17-mediated autophagic flux: Quercetin's therapeutic mechanism in diabetic nephropathy.
Identification of ferroptosis-related genes as diagnostic biomarkers and therapeutic targets in sorafenib-resistant HCC via machine learning and experimental validation.
Ribosome-binding protein 1 maintains peroxisome biogenesis.
Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restores anti-tumor immunity.
E2F1-autophagy-ALDH1A1 axis enhances self-renewal and drug resistance of lung cancer stem-like cells in a p53-dependent manner.
USP19 potentiates autophagic cell death via inhibiting mTOR pathway through deubiquitinating NEK9 in pancreatic cancer.
Pharmacological targeting of the mitochondrial phosphatase PTPMT1 sensitizes hepatocellular carcinoma to ferroptosis.
Progranulin enhances M2 macrophage polarization and renal fibrosis by modulating autophagy in chronic kidney disease.
LncRNA HITT inhibits autophagy by attenuating ATG12-ATG5-ATG16L1 complex formation.
Autophagy inhibition enhances antifibrotic potential of placental mesenchymal stem cells of fetal origin via regulating TGF-β1 mediated protein degradation of HGF.
Inhibition of anlotinib-induced autophagy attenuates invasion and migration by regulating epithelial-mesenchymal transition and cytoskeletal rearrangement through ATG5 in human osteosarcoma cells.
Metallothionein 3 Potentiates Pulmonary Artery Smooth Muscle Cell Proliferation by Promoting Zinc-MTF1-ATG5 Axis-mediated Autophagosome Formation.
The PI3K/Akt-Nrf2 Signaling Pathway and Mitophagy Synergistically Mediate Hydroxytyrosol to Alleviate Intestinal Oxidative Damage.
PEI/MMNs@LNA-542 nanoparticles alleviate ICU-acquired weakness through targeted autophagy inhibition and mitochondrial protection.
MicroRNA-204-5p Ameliorates Renal Injury via Regulating Keap1/Nrf2 Pathway in Diabetic Kidney Disease.
Yunnan Baiyao Might Mitigate Periodontitis Bone Destruction by Inhibiting Autophagy and Promoting Osteoblast Differentiation in vivo, ex vivo and in vitro.
Protective effect of naringenin on cadmium chloride-induced renal injury via alleviating oxidative stress, endoplasmic reticulum stress, and autophagy in chickens.
FUNDC1 alleviates doxorubicin-induced cardiotoxicity by restoring mitochondrial-endoplasmic reticulum contacts and blocked autophagic flux.
Mutant NOTCH3ECD Triggers Defects in Mitochondrial Function and Mitophagy in CADASIL Cell Models.
ONC206 targeting ClpP induces mitochondrial dysfunction and protective autophagy in hepatocellular carcinoma cells.
Ferroptosis induced by plasma-activated Ringer's lactate solution prevents oral cancer progression.
The p97-UBXD8 complex maintains peroxisome abundance by suppressing pexophagy.
Coxsackievirus group B3 regulates ASS1-mediated metabolic reprogramming and promotes macrophage inflammatory polarization in viral myocarditis.
DMDD, isolated from Averrhoa carambola L., ameliorates diabetic nephropathy by regulating endoplasmic reticulum stress-autophagy crosstalk.
Autophagy aggravates multi-walled carbon nanotube-induced ferroptosis by suppressing PGC-1 dependent-mitochondrial biogenesis in lung epithelial cells.
Central role of Sigma-1 receptor in ochratoxin A-induced ferroptosis.
Inflammatory microenvironment of moderate pulpitis enhances the osteo-/odontogenic potential of dental pulp stem cells by autophagy.
Circadian gene CLOCK accelerates atherosclerosis by promoting endothelial autophagy.
Targeting SMYD2 promotes ferroptosis and impacts the progression of pancreatic cancer through the c-Myc/NCOA4 axis-mediated ferritinophagy.
The RNA N6-methyladenosine demethylase FTO regulates ATG5 to inhibit malignant progression of uveal melanoma.
Hepatocyte-Specific HuR Protects Against Acetaminophen-Induced Liver Injury in Mice.
TBC1D4 antagonizes RAB2A-mediated autophagic and endocytic pathways.
Phillyrin promotes autophagosome formation in A53T-αSyn-induced Parkinson's disease model via modulation of REEP1.
Zosuquidar Promotes Antitumor Immunity by Inducing Autophagic Degradation of PD-L1.
Ergothioneine ameliorates metabolic dysfunction-Associated Steatotic Liver Disease (MASLD) by enhancing autophagy, inhibiting oxidative damage and inflammation.
Hepatocyte-derived Fetuin-A promotes alcohol-associated liver disease in mice by inhibiting autophagy-lysosome degradation of TLR and M2 macrophage polarization.
Autophagy-related protein 5 (ATG5) interacts with bone marrow stromal cell antigen 2 (BST2) to stimulate HBV replication through antagonizing the antiviral activity of BST2.
Combining large-spot low-fluence 1064-nm and fractional 1064-nm picosecond lasers for promoting protective melanosome autophagy via the PI3K/Akt/mTOR signalling pathway for the treatment of melasma.
circUSP13 facilitates the fast-to-slow myofiber shift via the MAPK/ERK signaling pathway in goat skeletal muscles.
Heme oxygenase 1 (HO1) regulates autophagy and apoptosis via the PI3K/AKT/mTOR signaling pathway of yak Sertoli cells.
N6-Methyladenosine Modification of lncCCKAR-5 Regulates Autophagy in Human Umbilical Cord Mesenchymal Stem Cells by Destabilizing LMNA and Inhibits Diabetic Wound Healing.
miR-155-5p promotes hepatic steatosis via PICALM-mediated autophagy in aging hepatocytes.
Urolithin A Hijacks ERK1/2-ULK1 Cascade to Improve CD8(+) T Cell Fitness for Antitumor Immunity.
Pectinose induces cell cycle arrest in luminal A and triple-negative breast cancer cells by promoting autophagy through activation of the p38 MAPK signaling pathway.
D-arabinose induces cell cycle arrest by promoting autophagy via p38 MAPK signaling pathway in breast cancer.
Vitamin D Receptor Activation Reduces Hepatic Inflammation via Enhancing Macrophage Autophagy in Cholestatic Mice.
Qingguang'an-induced autophagy in TFs inhibits scar formation: A follow-up in vivo mechanistic investigation.
Kaempferol improves Pb-induced cognitive impairments via inhibiting autophagy.
Dihydromyricetin ameliorates hepatic steatosis and insulin resistance via AMPK/PGC-1α and PPARα-mediated autophagy pathway.
Co-exposure to polystyrene nanoplastics and triclosan induces synergistic cytotoxicity in human KGN granulosa cells by promoting reactive oxygen species accumulation.
Effective-components combination alleviates PM2.5-induced inflammation by evoking macrophage autophagy in COPD.
FTO demethylates regulates cell-cycle progression by controlling CCND1 expression in luteinizing goat granulosa cells.
TRIM28-Mediated Excessive Oxidative Stress Induces Cellular Senescence in Granulosa Cells and Contributes to Premature Ovarian Insufficiency In Vitro and In Vivo.
Senecavirus A induces mitophagy to promote self-replication through direct interaction of 2C protein with K27-linked ubiquitinated TUFM catalyzed by RNF185.
CAPN2 promotes apalutamide resistance in metastatic hormone-sensitive prostate cancer by activating protective autophagy.
TGF β1 promotes the polarization of M2-type macrophages and activates PI3K/mTOR signaling pathway by inhibiting ISG20 to sensitize ovarian cancer to cisplatin.
Lycorine attenuated proliferation and induced apoptosis on imatinib-resistant K562 cell by inhibiting autophagy.
ENO1 contributes to the gemcitabine resistance of pancreatic cancer through the YAP1 signaling pathway.
Fibroblast growth factor 21 alleviates idiopathic pulmonary fibrosis by inhibiting PI3K-AKT-mTOR signaling and stimulating autophagy.
Exploring the Molecular Mechanism of Schisandrin C for the Treatment of Atherosclerosis via the PI3K/AKT/mTOR Autophagy Pathway.
DKK1 loss promotes endometrial fibrosis via autophagy and exosome-mediated macrophage-to-myofibroblast transition.
Zearalenone modulates the function of goat endometrial cells via the mitochondrial quality control system.
Combination of mangiferin and T0901317 targeting autophagy promotes cholesterol efflux from macrophage foam cell in atherosclerosis.
Diterpenoid WT-29 isolated from Wedelia exerted anti-inflammatory and anti-allergic activities.
Antioxidative Sirt1 and the Keap1-Nrf2 Signaling Pathway Impair Inflammation and Positively Regulate Autophagy in Murine Mammary Epithelial Cells or Mammary Glands Infected with Streptococcus uberis.
Liensinine alleviates mouse intestinal injury induced by sepsis through inhibition of oxidative stress, inflammation, and cell apoptosis.
Phomopsterone B Alleviates Liver Fibrosis through mTOR-Mediated Autophagy and Apoptosis Pathway.
Fluorochloridone induces mitochondrial dysfunction and apoptosis in primary goat Sertoli cells.
ATF4/PHGDH mediates the effects of ER stress on cadmium-induced autophagy and glycolysis.
m6A reader YTHDC2 mediates NCOA4 mRNA stability affecting ferritinophagy to alleviate secondary injury after intracerebral haemorrhage.
Mycobacterium manipulate glutaminase 1 mediated glutaminolysis to regulate macrophage autophagy for bacteria intracellular survival.
Taxifolin attenuates hepatic ischemia-reperfusion injury by enhancing PINK1/Parkin-mediated mitophagy.
Autophagy-mediated activation of the AIM2 inflammasome enhances M1 polarization of microglia and exacerbates retinal neovascularization.
Icariin Ameliorates D-galactose-induced Cell Injury in Neuron-like PC12 Cells by Inhibiting MPTP Opening.
Hepatoprotective effect of dietary pterostilbene against high-fat-diet-induced lipid accumulation exacerbated by chronic jet lag via SIRT1 and SIRT3 activation.
The heat shock protein DNAJB8 inhibits pseudorabies virus replication by autophagy.
Targeting Rab7-Rilp Mediated Microlipophagy Alleviates Lipid Toxicity in Diabetic Cardiomyopathy.
Colchicine-mediated selective autophagic degradation of HBV core proteins inhibits HBV replication and HBV-related hepatocellular carcinoma progression.
Synthetic lethality of combined ULK1 defection and p53 restoration induce pyroptosis by directly upregulating GSDME transcription and cleavage activation through ROS/NLRP3 signaling.
Cetylpyridinium chloride triggers paraptosis to suppress pancreatic tumor growth via the ERN1-MAP3K5-p38 pathway.
Yunnan Baiyao Inhibits Periodontitis by Suppressing the Autophagic Flux.
Breast cancer cells have an increased ferroptosis risk induced by system x(c)(-) blockade after deliberately downregulating CYTL1 to mediate malignancy.
GBP2 enhances paclitaxel sensitivity in triple‑negative breast cancer by promoting autophagy in combination with ATG2 and inhibiting the PI3K/AKT/mTOR pathway.
Polyvinyl alcohol/carboxymethyl chitosan-based hydrogels loaded with taxifolin liposomes promote diabetic wound healing by inhibiting inflammation and regulating autophagy.
Corynoxine triggers cell death via activating PP2A and regulating AKT-mTOR/GSK3β axes in NSCLC.
Dexamethasone upregulates macrophage PIEZO1 via SGK1, suppressing inflammation and increasing ROS and apoptosis.
Tris-Functionalized Polyoxotungstovanadate-Mediated Antitumor Efficacy Involves Multiple Cell Death Pathways.
Selenomethionine Inhibits NF-κB-mediated Inflammatory Responses of Bovine Mammary Epithelial Cells Caused by Klebsiella pneumoniae by Increasing Autophagic Flux.
Ginsenoside Rk1 induces autophagy-dependent apoptosis in hepatocellular carcinoma by AMPK/mTOR signaling pathway.
Myricetin Oligomer Triggers Multi-Receptor Mediated Penetration and Autophagic Restoration of Blood-Brain Barrier for Ischemic Stroke Treatment.
Suppression of hypoxia-induced CAV1 autophagic degradation enhances nanoalbumin-paclitaxel transcytosis and improves therapeutic activity in pancreatic cancer.
PM2.5 exposure-induced senescence-associated secretory phenotype in airway smooth muscle cells contributes to airway remodeling.
Lycium barbarum Polysaccharides Regulating miR-181/Bcl-2 Decreased Autophagy of Retinal Pigment Epithelium with Oxidative Stress.
Inhibition of TRF2 Leads to Ferroptosis, Autophagic Death, and Apoptosis by Causing Telomere Dysfunction.
P16(INK4a) Regulates ROS-Related Autophagy and CDK4/6-Mediated Proliferation: A New Target of Myocardial Regeneration Therapy.
TNFR2 deficiency impairs the growth of mouse colon cancer.
Vitamin D Receptor Activation Targets ROS-Mediated Crosstalk Between Autophagy and Apoptosis in Hepatocytes in Cholestasic Mice.
Aspirin-triggered Resolvin D1 ameliorates activation of the NLRP3 inflammasome via induction of autophagy in a rat model of neuropathic pain.
A new insight of cadmium-induced cellular evidence of autophagic-associated spermiophagy during spermatogenesis.
Elsinochrome A induces cell apoptosis and autophagy in photodynamic therapy.
Macrophage migration inhibitory factor exacerbates asthmatic airway remodeling via dynamin-related protein 1-mediated autophagy activation.
Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) alleviate excessive autophagy of ovarian granular cells through VEGFA/PI3K/AKT/mTOR pathway in premature ovarian failure rat model.
Cancer/testis antigen CAGE mediates osimertinib resistance in non-small cell lung cancer cells and predicts poor prognosis in patients with pulmonary adenocarcinoma.
Co-exposure to environmentally relevant concentrations of cadmium and polystyrene nanoplastics induced oxidative stress, ferroptosis and excessive mitophagy in mice kidney.
Streptococcus uberis induced expressions of pro-inflammatory IL-6, TNF-α, and IFN-γ in bovine mammary epithelial cells associated with inhibited autophagy and autophagy flux formation.
Anti-rheumatoid arthritis effects of total saponins from Rhizoma Panacis Majoris on adjuvant-induced arthritis in rats and rheumatoid arthritis fibroblast-like synoviocytes.
SETDB1 Methylates MCT1 Promoting Tumor Progression by Enhancing the Lactate Shuttle.
CL4-modified exosomes deliver lncRNA DARS-AS1 siRNA to suppress triple-negative breast cancer progression and attenuate doxorubicin resistance by inhibiting autophagy.
Ligustrazine and liguzinediol protect against doxorubicin-induced cardiomyocytes injury by inhibiting mitochondrial apoptosis and autophagy.
Bilirubin impacts microglial autophagy via the Akt-mTOR signaling pathway.
ATAD1 inhibits hepatitis C virus infection by removing the viral TA-protein NS5B from mitochondria.
Inhibiting autophagy to boost antitumor immunity with tetramethylpyrazine-loaded and PD-L1-targeting liposomal nanoparticles.
Lipid phosphatase SAC1 suppresses hepatitis B virus replication through promoting autophagic degradation of virions.
Ambra1 modulates the sensitivity of mantle cell lymphoma to palbociclib by regulating cyclin D1.
Role of nuclear factor of activated T Cells-1 in Sepsis-induced behavioral deficits in mice.
RAB7A GTPase Is Involved in Mitophagosome Formation and Autophagosome-Lysosome Fusion in N2a Cells Treated with the Prion Protein Fragment 106-126.
Effects of icariin and curcumol on autophagy, ferroptosis, and lipid metabolism based on miR-7/m-TOR/SREBP1 pathway on prostate cancer.
Neuroprotective effect of Vesatolimod in an experimental autoimmune encephalomyelitis mice model.
Inhibition of TRADD ameliorates chondrocyte necroptosis and osteoarthritis by blocking RIPK1-TAK1 pathway and restoring autophagy.
TFEB coordinates autophagy and pyroptosis as hepatotoxicity responses to ZnO nanoparticles.
Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy.
Neuro death through autophagy via the acetylation of FoxO1 by SIRT2 in the hippocampus of mice in a autism spectrum disorder mice model.
VANGL2 inhibits antiviral IFN-I signaling by targeting TBK1 for autophagic degradation.
SIRT3-mediated autophagy contributes to ferroptosis-induced anticancer by inducing the formation of BECN1-SLC7A11 complex.
Cassiae Semen improves non-alcoholic fatty liver disease through autophagy-related pathway.
Recombinant humanized collagen type III with high antitumor activity inhibits breast cancer cells autophagy, proliferation, and migration through DDR1.
6-Methoxydihydrosanguinarine induces apoptosis and autophagy in breast cancer MCF-7 cells by accumulating ROS to suppress the PI3K/AKT/mTOR signaling pathway.
5'-tRF-GlyGCC promotes breast cancer metastasis by increasing fat mass and obesity-associated protein demethylase activity.
Purvalanol A induces apoptosis and reverses cisplatin resistance in ovarian cancer.
MALAT1-miR-30c-5p-CTGF/ATG5 axis regulates silica-induced experimental silicosis by mediating EMT in alveolar epithelial cells.
Impaired autophagy flux by lncRNA NEAT1 is critical for inflammation factors production in human periodontal ligament stem cells with nicotine treatment.
Stimulation of Hepatic Ferritinophagy Mitigates Irp2 Depletion-Induced Anemia.
BMAL1/p53 mediating bronchial epithelial cell autophagy contributes to PM2.5-aggravated asthma.
Isovitexin alleviates hepatic fibrosis by regulating miR-21-mediated PI3K/Akt signaling and glutathione metabolic pathway: based on transcriptomics and metabolomics.
Hepatotoxicity of the Pesticide Avermectin Exposure to Freshwater-Farmed Carp: Evidence from In Vivo and In Vitro Research.
KPNA2 suppresses porcine epidemic diarrhea virus replication by targeting and degrading virus envelope protein through selective autophagy.
Didymin alleviates metabolic dysfunction-associated fatty liver disease (MAFLD) via the stimulation of Sirt1-mediated lipophagy and mitochondrial biogenesis.
Thymoquinone induces apoptosis and protective autophagy in gastric cancer cells by inhibiting the PI3K/Akt/mTOR pathway.
NLRC5 restricts dengue virus infection by promoting the autophagic degradation of viral NS3 through E3 ligase CUL2 (cullin 2).
A Novel Tri-Functional Liposome Re-Educates "Cold Tumor" and Abrogates Tumor Growth by Synergizing Autophagy Inhibition and PD-L1 Blockade.
Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.
CCPG1 recognizes endoplasmic reticulum luminal proteins for selective ER-phagy.
Evaluation of the synergistic effects of epigallocatechin-3-gallate-loaded PEGylated-PLGA nanoparticles with nimodipine against neuronal injury after subarachnoid hemorrhage.
Theabrownins Produced via Chemical Oxidation of Tea Polyphenols Inhibit Human Lung Cancer Cells in vivo and in vitro by Suppressing the PI3K/AKT/mTOR Pathway Activation and Promoting Autophagy.
Cigarette Smoke Exposure Increases Glucose-6-phosphate Dehydrogenase, Autophagy, Fibrosis, and Senescence in Kidney Cells In Vitro and In Vivo.
LINC-PINT suppresses cisplatin resistance in gastric cancer by inhibiting autophagy activation via epigenetic silencing of ATG5 by EZH2.
Coxsackievirus B3 infection induces glycolysis to facilitate viral replication.
Chrysophanol-8-O-glucoside protects mice against acute liver injury by inhibiting autophagy in hepatic stellate cells and inflammatory response in liver-resident macrophages.
Toxoplasma gondii CDPK3 Controls the Intracellular Proliferation of Parasites in Macrophages.
Chlorin e6-Induced Photodynamic Effect Polarizes the Macrophage Into an M1 Phenotype Through Oxidative DNA Damage and Activation of STING.
ALG-bFGF Hydrogel Inhibiting Autophagy Contributes to Protection of Blood-Spinal Cord Barrier Integrity via PI3K/Akt/FOXO1/KLF4 Pathway After SCI.
Porcine cGAS-STING signaling induced autophagy inhibits STING downstream IFN and apoptosis.
Huaier suppresses pancreatic cancer progression via activating cell autophagy induced ferroptosis.
Polyvinylpyrrolidone-Modified Taxifolin Liposomes Promote Liver Repair by Modulating Autophagy to Inhibit Activation of the TLR4/NF-κB Signaling Pathway.
Autophagy mediates the clearance of oligodendroglial SNCA/alpha-synuclein and TPPP/p25A in multiple system atrophy models.
Selenomethionine alleviates NF-κB-mediated inflammation in bovine mammary epithelial cells induced by Escherichia coli by enhancing autophagy.
Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.
Activating PPARβ/δ Protects against Endoplasmic Reticulum Stress-Induced Astrocytic Apoptosis via UCP2-Dependent Mitophagy in Depressive Model.
Malvidin protects against lipopolysaccharide-induced acute liver injury in mice via regulating Nrf2 and NLRP3 pathways and suppressing apoptosis and autophagy.
New insights into the interaction between duodenal toxicity and microbiota disorder under copper exposure in chicken: Involving in endoplasmic reticulum stress and mitochondrial toxicity.
Difenoconazole disrupts the blood-brain barrier and results in neurotoxicity in carp by inhibiting the Nrf2 pathway mediated ROS accumulation.
N-linoleyltyrosine protects neurons against Aβ(1-40)-induced cell toxicity via autophagy involving the CB(2)/AMPK/mTOR/ULK1 pathway.
Berbamine hydrochloride inhibits bovine viral diarrhea virus replication via interfering in late-stage autophagy.
Bifendate inhibits autophagy at multiple steps and attenuates oleic acid-induced lipid accumulation.
O-GlcNAcylation of SIRT1 Protects against Cold Stress-Induced Skeletal Muscle Damage via Amelioration of Mitochondrial Homeostasis.
Gaseous signal molecule SO(2) regulates autophagy through PI3K/AKT pathway inhibits cardiomyocyte apoptosis and improves myocardial fibrosis in rats with type II diabetes.
Repeated social defeat stress inhibits development of hippocampus neurons through mitophagy and autophagy.
Elevated ATG13 in serum of patients with ME/CFS stimulates oxidative stress response in microglial cells via activation of receptor for advanced glycation end products (RAGE).
CCDC50 suppresses NLRP3 inflammasome activity by mediating autophagic degradation of NLRP3.
Quercus acutissima Carruth. root extract triggers apoptosis, autophagy and inhibits cell viability in breast cancer cells.
Sec23a inhibits the self-renewal of melanoma cancer stem cells via inactivation of ER-phagy.
Dietary folic acid supplementation improves semen quality and spermatogenesis through altering autophagy and histone methylation in the testis of aged broiler breeder roosters.
Extracellular vesicles originating from autophagy mediate an antibody-resistant spread of classical swine fever virus in cell culture.
Decreased Krüppel-like factor 4 in adenomyosis impairs decidualization by repressing autophagy in human endometrial stromal cells.
Macrophages disseminate pathogen associated molecular patterns through the direct extracellular release of the soluble content of their phagolysosomes.
Integrated metabolism and epigenetic modifications in the macrophages of mice in responses to cold stress.
Autophagy deficiency promotes lung metastasis of prostate cancer via stabilization of TWIST1.
Extracellular vesicle miR-32 derived from macrophage promotes arterial calcification in mice with type 2 diabetes via inhibiting VSMC autophagy.
The Protective Effect of Lycium Ruthenicum Murr Anthocyanins in Cr (VI)-Induced Mitophagy in DF-1 Cells.
Ciliary Type III Adenylyl Cyclase in the VMH Is Crucial for High-Fat Diet-Induced Obesity Mediated by Autophagy.
Calycosin ameliorates atherosclerosis by enhancing autophagy via regulating the interaction between KLF2 and MLKL in apolipoprotein E gene-deleted mice.
Disruption of actin dynamics induces autophagy of the eukaryotic chaperonin TRiC/CCT.
The effect of QiangGuYin on osteoporosis through the AKT/mTOR/autophagy signaling pathway mediated by CKIP-1.
PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells by phosphorylating PRAS40.
Muyin extract inhibits non-small-cell lung cancer growth by inducing autophagy and apoptosis in vitro and in vivo.
The dynamic changes in autophagy activity and its role in lung injury after deep hypothermic circulatory arrest.
S-20, a steroidal saponin from the berries of black nightshade, exerts anti-multidrug resistance activity in K562/ADR cells through autophagic cell death and ERK activation.
ATP6V1H deficiency impairs glucose tolerance by augmenting endoplasmic reticulum stress in high fat diet fed mice.
Ultrasound-triggered microbubble destruction enhances the radiosensitivity of glioblastoma by inhibiting PGRMC1-mediated autophagy in vitro and in vivo.
Inhibition of HSPA8 by rifampicin contributes to ferroptosis via enhancing autophagy.
ATG5-Mediated Autophagy May Inhibit Pyroptosis to Ameliorate Oleic Acid-Induced Hepatocyte Steatosis.
Loss of ATG5 in KRT14(+) cells leads to accumulated functional impairments of salivary glands via pyroptosis.
Highly expressed SERCA2 triggers tumor cell autophagy and is a druggable vulnerability in triple-negative breast cancer.
Targeting CRL4 suppresses chemoresistant ovarian cancer growth by inducing mitophagy.
Sulforaphane Ameliorates Hepatic Lipid Metabolism via Modulating Lipophagy In Vivo and In Vitro.
Endosomal lipid signaling reshapes the endoplasmic reticulum to control mitochondrial function.
LncRNA CCAT1 Upregulates ATG5 to Enhance Autophagy and Promote Gastric Cancer Development by Absorbing miR-140-3p.
Oridonin relieves depressive-like behaviors by inhibiting neuroinflammation and autophagy impairment in rats subjected to chronic unpredictable mild stress.
CD13 downregulation mediated by ubenimex inhibits autophagy to overcome 5-FU resistance by disturbing the EMP3/FAK/NF-κB pathway in gastric cancer cells.
Mucin O-glycan-microbiota axis orchestrates gut homeostasis in a diarrheal pig model.
The microRNA-10b-Bim axis promotes cancer progression through activating autophagy in oral squamous cell carcinoma.
Acetyl CoA synthase 2 potentiates ATG5-induced autophagy against neuronal apoptosis after subarachnoid hemorrhage.
Asymmetric Pericentrosomal CD133 Endosomes Induce the Unequal Autophagic Activity During Cytokinesis in CD133-Positive Human Neuroblastoma Cells.
Let-7i-5p promotes a malignant phenotype in nasopharyngeal carcinoma via inhibiting tumor-suppressive autophagy.
LncRNA FEZF1-AS1 Promotes Multi-Drug Resistance of Gastric Cancer Cells via Upregulating ATG5.
Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS.
Autophagic Flux Unleashes GATA4-NF-κB Axis to Promote Antioxidant Defense-Dependent Survival of Colorectal Cancer Cells under Chronic Acidosis.
Silica Nanoparticles Promote α-Synuclein Aggregation and Parkinson's Disease Pathology.
FBXO22 Promotes Growth and Metastasis and Inhibits Autophagy in Epithelial Ovarian Cancers via the MAPK/ERK Pathway.
Characterization of Interplay Between Autophagy and Ferroptosis and Their Synergistical Roles on Manipulating Immunological Tumor Microenvironment in Squamous Cell Carcinomas.
Lactobacillus rhamnosus GR-1 Prevents Escherichia coli-Induced Apoptosis Through PINK1/Parkin-Mediated Mitophagy in Bovine Mastitis.
Taurine Alleviates Streptococcus uberis-Induced Inflammation by Activating Autophagy in Mammary Epithelial Cells.
SNHG9, a Papillary Thyroid Cancer Cell Exosome-Enriched lncRNA, Inhibits Cell Autophagy and Promotes Cell Apoptosis of Normal Thyroid Epithelial Cell Nthy-ori-3 Through YBOX3/P21 Pathway.
Degradation of lipid droplets by chimeric autophagy-tethering compounds.
Latcripin-7A from Lentinula edodes C91-3 induces apoptosis, autophagy, and cell cycle arrest at G1 phase in human gastric cancer cells via inhibiting PI3K/Akt/mTOR signaling.
UPF1 impacts on mTOR signaling pathway and autophagy in endometrioid endometrial carcinoma.
LncRNA OIP5-AS1 inhibits ferroptosis in prostate cancer with long-term cadmium exposure through miR-128-3p/SLC7A11 signaling.
The anticancer activity of root extract from Quercus acutissima Carruth. Via regulating apoptosis and autophagy in breast cancer cells.
Hepatoprotective effects of ginsenoside Rk3 in acetaminophen-induced liver injury in mice by activation of autophagy.
Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy.
Metformin sensitises hepatocarcinoma cells to methotrexate by targeting dihydrofolate reductase.
Macroautophagy supports Sonic Hedgehog signaling by promoting Patched1 degradation.
Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4.
OAB-14 Effectively Ameliorates the Dysfunction of the Endosomal-Autophagic-Lysosomal Pathway in APP/PS1 Transgenic Mice.
Exopolysaccharides from Bifidobacterium animalis Ameliorate Escherichia coli-Induced IPEC-J2 Cell Damage via Inhibiting Apoptosis and Restoring Autophagy.
Aristolochic acid I induces impairment in spermatogonial stem cell in rodents.
H(+)/Cl(‑) exchange transporter 7 promotes lysosomal acidification‑mediated autophagy in mouse cardiomyocytes.
Hypoxia-induced acetylation of PAK1 enhances autophagy and promotes brain tumorigenesis via phosphorylating ATG5.
Autophagy-induced p62 accumulation is required for curcumol to regulate KLF5-mediated angiogenesis in liver sinusoidal endothelial cells.
Nuclear translocation of ATG5 induces DNA mismatch repair deficiency (MMR-D)/microsatellite instability (MSI) via interacting with Mis18α in colorectal cancer.
Endoplasmic reticulum stress manipulates autophagic response that antagonizes polybrominated diphenyl ethers quinone induced cytotoxicity in microglial BV2 cells.
DUSP1 overexpression attenuates renal tubular mitochondrial dysfunction by restoring Parkin-mediated mitophagy in diabetic nephropathy.
Citrate activates autophagic death of prostate cancer cells via downregulation CaMKII/AKT/mTOR pathway.
Metformin attenuates atherosclerosis and plaque vulnerability by upregulating KLF2-mediated autophagy in apoE(-/-) mice.
Autophagy regulates functional differentiation of mammary epithelial cells.
CircCDK8 regulates osteogenic differentiation and apoptosis of PDLSCs by inducing ER stress/autophagy during hypoxia.
Autophagy Blockade Limits HER2+ Breast Cancer Tumorigenesis by Perturbing HER2 Trafficking and Promoting Release Via Small Extracellular Vesicles.
Saponins from Panax japonicus attenuate cognitive impairment in ageing rats through regulating microglial polarisation and autophagy.
Loss of SMARCB1 promotes autophagy and facilitates tumour progression in chordoma by transcriptionally activating ATG5.
Long‑chain non‑coding RNA GAS5 promotes cell autophagy by modulating the miR‑181c‑5p/ATG5 and miR‑1192/ATG12 axes.
6-Shogaol from ginger shows anti-tumor effect in cervical carcinoma via PI3K/Akt/mTOR pathway.
Ozone induces tolerance against cardiomyocytes oxygen-glucose deprivation/reperfusion through inhibition of autophagy pathway.
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
Mild hypothermia pretreatment extenuates liver ischemia-reperfusion injury through Rab7-mediated autophagosomes-lysosomes fusion.
Coibamide A kills cancer cells through inhibiting autophagy.
HDAC6 Regulates the Fusion of Autophagosome and Lysosome to Involve in Odontoblast Differentiation.
Autophagy Contributes to the Maintenance of Genomic Integrity by Reducing Oxidative Stress.
The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis.
The Effects of Puerarin on Autophagy Through Regulating of the PERK/eIF2α/ATF4 Signaling Pathway Influences Renal Function in Diabetic Nephropathy.
Empagliflozin Alleviates Hepatic Steatosis by Activating the AMPK-TET2-Autophagy Pathway in vivo and in vitro.
Cardamonin Reduces Acetaminophen-Induced Acute Liver Injury in Mice via Activating Autophagy and NFE2L2 Signaling.
CDKL3 Targets ATG5 to Promote Carcinogenesis of Esophageal Squamous Cell Carcinoma.
FTO accelerates ovarian cancer cell growth by promoting proliferation, inhibiting apoptosis, and activating autophagy.
NOD2/c-Jun NH(2)-Terminal Kinase Triggers Mycoplasma ovipneumoniae-Induced Macrophage Autophagy.
Autophagy plays a protective role during Pseudomonas aeruginosa-induced apoptosis via ROS-MAPK pathway.
Effect of autophagy on irradiation‑induced damage in osteoblast‑like MC3T3‑E1 cells.
Apatinib induces apoptosis and autophagy via the PI3K/AKT/mTOR and MAPK/ERK signaling pathways in neuroblastoma.
HIF-1α-Mediated Mitophagy Determines ZnO Nanoparticle-Induced Human Osteosarcoma Cell Death both In Vitro and In Vivo.
N‑linoleyltyrosine protects PC12 cells against oxidative damage via autophagy: Possible involvement of CB1 receptor regulation.
PINK1-mediated mitophagy protects against hepatic ischemia/reperfusion injury by restraining NLRP3 inflammasome activation.
Cannabinoid receptor 2 activation alleviates septic lung injury by promoting autophagy via inhibition of inflammatory mediator release.
ADAM12 silencing promotes cellular apoptosis by activating autophagy in choriocarcinoma cells.
Yeast β-D-glucan exerts antitumour activity in liver cancer through impairing autophagy and lysosomal function, promoting reactive oxygen species production and apoptosis.
Upregulated NTF4 in colorectal cancer promotes tumor development via regulating autophagy.
The RBP1-CKAP4 axis activates oncogenic autophagy and promotes cancer progression in oral squamous cell carcinoma.
Galangin Protects against Symptoms of Dextran Sodium Sulfate-induced Acute Colitis by Activating Autophagy and Modulating the Gut Microbiota.
The Preparation of Ginsenoside Rg5, Its Antitumor Activity against Breast Cancer Cells and Its Targeting of PI3K.
Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1-dependent mitophagy in a Salmonella infantis model of piglet diarrhea.
α-synuclein promotes progression of Parkinson's disease by upregulating autophagy signaling pathway to activate NLRP3 inflammasome.
High mobility group box 1 antibody represses autophagy and alleviates hippocampus damage in pilocarpine-induced mouse epilepsy model.
MDM2 inhibition-mediated autophagy contributes to the pro-apoptotic effect of berberine in p53-null leukemic cells.
Latcripin-7A, derivative of Lentinula edodes C(91-3), reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G(1) phase in breast cancer cells.
Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress-autophagy axis and improves myocardial reconstruction after acute myocardial infarction.
Graphene oxide size-dependently altered lipid profiles in THP-1 macrophages.
S100A8 transported by SEC23A inhibits metastatic colonization via autocrine activation of autophagy.
Butyrate-mediated autophagy inhibition limits cytosolic Salmonella Infantis replication in the colon of pigs treated with a mixture of Lactobacillus and Bacillus.
Lactobacillus johnsonii L531 Ameliorates Escherichia coli-Induced Cell Damage via Inhibiting NLRP3 Inflammasome Activity and Promoting ATG5/ATG16L1-Mediated Autophagy in Porcine Mammary Epithelial Cells.
Loss of Mitochondrial DNA by Gemcitabine Triggers Mitophagy and Cell Death.
Mangiferin Prevents TBHP-Induced Apoptosis and ECM Degradation in Mouse Osteoarthritic Chondrocytes via Restoring Autophagy and Ameliorates Murine Osteoarthritis.
LncRNA expression profile during autophagy and Malat1 function in macrophages.
The ginsenoside Rk3 exerts anti-esophageal cancer activity in vitro and in vivo by mediating apoptosis and autophagy through regulation of the PI3K/Akt/mTOR pathway.
Autophagy: a new mechanism for regulating VEGF and PEDF expression in retinal pigment epithelium cells.
Fish Autophagy Protein 5 Exerts Negative Regulation on Antiviral Immune Response Against Iridovirus and Nodavirus.
Pterostilbene, An Active Constituent of Blueberries, Suppresses Proliferation Potential of Human Cholangiocarcinoma via Enhancing the Autophagic Flux.
Sequential formation of different layers of dystrophic neurites in Alzheimer's brains.
Sodium fluoride regulates the osteo/odontogenic differentiation of stem cells from apical papilla by modulating autophagy.
Effects of long-term fluoride exposure on cognitive ability and the underlying mechanisms: Role of autophagy and its association with apoptosis.
Ginsenoside Rg5 induces G2/M phase arrest, apoptosis and autophagy via regulating ROS-mediated MAPK pathways against human gastric cancer.
Homocysteine induces human mesangial cell apoptosis via the involvement of autophagy and endoplasmic reticulum stress.
Icariin induces apoptosis by suppressing autophagy in tamoxifen-resistant breast cancer cell line MCF-7/TAM.
Adiponectin inhibits high glucose-induced angiogenesis via inhibiting autophagy in RF/6A cells.
Promising therapeutic effect of thapsigargin nanoparticles on chronic kidney disease through the activation of Nrf2 and FoxO1.
Roles of mitochondrial fission inhibition in developmental fluoride neurotoxicity: mechanisms of action in vitro and associations with cognition in rats and children.
Repression of MicroRNA-30e by Hepatitis C Virus Enhances Fatty Acid Synthesis.
The exosome-like vesicles from osteoarthritic chondrocyte enhanced mature IL-1β production of macrophages and aggravated synovitis in osteoarthritis.
Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation.
Hypothermic oxygenated machine perfusion alleviates liver injury in donation after circulatory death through activating autophagy in mice.
Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy.
Autophagy exerts pivotal roles in regulatory effects of 1α,25-(OH)(2)D(3) on the osteoclastogenesis.
Autophagy Mediates Interleukin-1β Secretion in Human Neutrophils.
Promyelocytic Leukemia Restricts Enterovirus 71 Replication by Inhibiting Autophagy.
MicroRNA-9a-5p Alleviates Ischemia Injury After Focal Cerebral Ischemia of the Rat by Targeting ATG5-Mediated Autophagy.
Autophagy activation and the mechanism of retinal microvascular endothelial cells in hypoxia.
Resveratrol relieves particulate matter (mean diameter < 2.5 μm)-induced oxidative injury of lung cells through attenuation of autophagy deregulation.
LP1 from Lentinula edodes C(91-3) Induces Autophagy, Apoptosis and Reduces Metastasis in Human Gastric Cancer Cell Line SGC-7901.
Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.
RAB37 interacts directly with ATG5 and promotes autophagosome formation via regulating ATG5-12-16 complex assembly.
7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway.
Retigabine ameliorates acute stress-induced impairment of spatial memory retrieval through regulating USP2 signaling pathways in hippocampal CA1 area.
Autophagy defects and related genetic variations in renal cell carcinoma with eosinophilic cytoplasmic inclusions.
CXCR4-mediated signaling regulates autophagy and influences acute myeloid leukemia cell survival and drug resistance.
Antagonizing peroxisome proliferator-activated receptor γ facilitates M1-to-M2 shift of microglia by enhancing autophagy via the LKB1-AMPK signaling pathway.
The gastric mucosal protective effects of astragaloside IV in mnng-induced GPL rats.
Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling.
SYNJ2BP promotes the degradation of PTEN through the lysosome-pathway and enhances breast tumor metastasis via PI3K/AKT/SNAI1 signaling.
Fluoride-Induced Autophagy via the Regulation of Phosphorylation of Mammalian Targets of Rapamycin in Mice Leydig Cells.
ATF4/ATG5 Signaling in Hypothalamic Proopiomelanocortin Neurons Regulates Fat Mass via Affecting Energy Expenditure.
Anti-osteoclastogenesis of Mineral Trioxide Aggregate through Inhibition of the Autophagic Pathway.
TNF-α stimulates endothelial palmitic acid transcytosis and promotes insulin resistance.
7-O-geranylquercetin-induced autophagy contributes to apoptosis via ROS generation in human non-small cell lung cancer cells.
miR-130a upregulates mTOR pathway by targeting TSC1 and is transactivated by NF-κB in high-grade serous ovarian carcinoma.
Protease-activated receptor-2 promotes kidney tubular epithelial inflammation by inhibiting autophagy via the PI3K/Akt/mTOR signalling pathway.
Low-Dose Endothelial-Monocyte-Activating Polypeptide-II Induced Autophagy by Down-Regulating miR-20a in U-87 and U-251 Glioma Cells.
Nanoparticle-facilitated autophagy inhibition promotes the efficacy of chemotherapeutics against breast cancer stem cells.
Autophagy-mediated clearance of ubiquitinated mutant huntingtin by graphene oxide.
Bifidobacterial recombinant thymidine kinase-ganciclovir gene therapy system induces FasL and TNFR2 mediated antitumor apoptosis in solid tumors.
Quinones Derived from Polychlorinated Biphenyls Induce ROS-Dependent Autophagy by Evoking an Autophagic Flux and Inhibition of mTOR/p70S6k.
Interplay of autophagy and apoptosis during PRRSV infection of Marc145 cell.
Anti-osteoclastogenic activity of isoliquiritigenin via inhibition of NF-κB-dependent autophagic pathway.
Upregulation of ATG3 contributes to autophagy induced by the detachment of intestinal epithelial cells from the extracellular matrix, but promotes autophagy-independent apoptosis of the attached cells.
Expression of autophagy-related proteins ATG5 and FIP200 predicts favorable disease-free survival in patients with breast cancer.
Connexin 31.1 degradation requires the Clathrin-mediated autophagy in NSCLC cell H1299.
Potent effects of dioscin against obesity in mice.
Suppression of autophagy augments the radiosensitizing effects of STAT3 inhibition on human glioma cells.
Differential ERK activation during autophagy induced by europium hydroxide nanorods and trehalose: Maximum clearance of huntingtin aggregates through combined treatment.
Atg5 but not Atg7 in dendritic cells enhances IL-2 and IFN-γ production by Toxoplasma gondii-reactive CD4+ T cells.
Effects of the total saponins from Rosa laevigata Michx fruit against acetaminophen-induced liver damage in mice via induction of autophagy and suppression of inflammation and apoptosis.
Japanese encephalitis virus activates autophagy as a viral immune evasion strategy.
Piperlongumine induces autophagy by targeting p38 signaling.
Syntaxin 13, a genetic modifier of mutant CHMP2B in frontotemporal dementia, is required for autophagosome maturation.
P38 MAP kinase functions as a switch in MS-275-induced reactive oxygen species-dependent autophagy and apoptosis in human colon cancer cells.
Subversion of cellular autophagy machinery by hepatitis B virus for viral envelopment.
The CD40-autophagy pathway is needed for host protection despite IFN-Γ-dependent immunity and CD40 induces autophagy via control of P21 levels.
Autophagy is essential for mitochondrial clearance in mature T lymphocytes.
A plant triterpenoid, avicin D, induces autophagy by activation of AMP-activated protein kinase.
Ye W, Li Y, Wang W, Pan D, Wang X, Gu Y, Zhu Y, Wang H, Lu X, Jiang D, Tang P, Shu H, Ma J, Cai W
International journal of biological sciences 2026;22(2):858-875
International journal of biological sciences 2026;22(2):858-875
RNA-binding motif protein 15 promotes gastric cancer growth and drug resistance via USP10-mediated deubiquitination and stabilization of nuclear NRF2.
Ma Z, Xu Z, Xu J, Chen C, Niu W, Wang Y, Qian Y, Zhang X, Yang M, Stefan SM, Gan L, Wang S, Wang B
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101376
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101376
Porcine reproductive and respiratory syndrome virus nsp2 protects viral RNA-dependent RNA polymerase from autophagic degradation.
Zhu T, Jiao X, Shi J, Wang B, Li C, Li Y
Veterinary microbiology 2026 May;316:110993
Veterinary microbiology 2026 May;316:110993
High-fat diet perturbs hepatic lipid metabolism and impairs colonic autophagy to exacerbate experimental colitis.
Xu T, Shi J, Ji J, Ma C, Li J
3 Biotech 2026 May;16(5):171
3 Biotech 2026 May;16(5):171
AMBRA1 enhances Sonic Hedgehog signaling during cerebellar development and in medulloblastoma.
Basili I, Bufalieri F, Conenna M, Navacci S, Li YR, Torrejon J, Bernardi F, Lospinoso Severini L, Marsaud V, Cancila G, Bourmeau G, Yu H, Lo Re V, Talbot J, Adabbo G, Di Pinto A, Agnoli F, Giovannini D, Leonardi S, Bordone R, Petroni M, Souphron J, Blauwblomme T, Beccaria K, Dufour C, D'Angelo L, De Smaele E, Canettieri G, Giannini G, Fimia GM, Maroder M, Guardavaccaro D, Pazzaglia S, Tsai JW, Infante P, Ayrault O, Di Marcotullio L
Developmental cell 2026 May 13;61(5):1111-1126.e9
Developmental cell 2026 May 13;61(5):1111-1126.e9
Ixazomib triggers autophagic degradation of MUC5AC/integrin-β4 and inhibits non-small cell lung cancer progression.
Appadurai MI, Alsafwani ZW, Chaudhary S, Shah A, Somavarapu P, Dooshety SN, Kubicek BS, Batra SK, Lakshmanan I, Ganti AK
Cancer letters 2026 May 1;645:218333
Cancer letters 2026 May 1;645:218333
Homoharringtonine inhibits growth and migration in non-small cell lung cancer via PDIA4-mediated modulation of autophagy and EMT.
Ma X, Lei P, Ren B, Xie S, Zhang Y, Wang Y, Ma W
Archives of pharmacal research 2026 Mar;49(3):357-374
Archives of pharmacal research 2026 Mar;49(3):357-374
Lactucopicrin promotes the autophagic degradation of MAP2K4/MKK4 by mediating CCDC50 palmitoylation to alleviate osteoarthritis progression.
Li W, Sun Q, Hu K, Tang D, Yang C, Xie Y, Peng X, Deng Y, Lu J, Qi Y, Lin Y, Sun H, Tian Q, Xu C, Tian X, Jiang H
Autophagy 2026 Mar;22(3):526-544
Autophagy 2026 Mar;22(3):526-544
PSAT1 inhibits mTORC1 activation by preventing Rag heterodimer formation in lung adenocarcinoma.
Liu Y, Cheng Z, Zhang J, Zhang Y, Zhao T, Sun L, Wen G, Han T, Wang J
Autophagy 2026 Mar;22(3):468-483
Autophagy 2026 Mar;22(3):468-483
Nitric Oxide Donor Alleviates Cardiac Arrest Induced Blood Brain Barrier Injury by Inhibiting HMGB1-ATG5 Mediated Endothelial Autophagy.
Duan P, Bi Y, Feng W, Jin Z, Meng Y, Li H, Li X, Luo L, Zhao X, Zhang B
Cellular and molecular neurobiology 2026 Mar 6;46(1)
Cellular and molecular neurobiology 2026 Mar 6;46(1)
Neurons with granulovacuolar degeneration bodies are resilient to tau-induced protein synthesis impairment.
Smits JFM, Ligthart TW, Jorge-Oliva M, Middelhoff S, Schipper F, Pita-Illobre D, Li KW, Scheper W
Science advances 2026 Mar 6;12(10):eaea8940
Science advances 2026 Mar 6;12(10):eaea8940
Small-molecule enhancement of METTL3 S-palmitoylation as a therapeutic strategy for osteoarthritis.
Qin W, Wei J, Li F, Wang L, Zhang Q, Chen J, Lu P, Long T, Liu A, Cao J, Deng Y, Zhang H, Chen D, Cui J, Zhao W
Cell reports 2026 Mar 24;45(3):116993
Cell reports 2026 Mar 24;45(3):116993
Buyang Huanwu decoction facilitates the repair of red nucleus neurons subsequent to spinal cord injury in rats via autophagy.
Deng J, Zhang Y, Xie W, Li L, Li Q
The journal of spinal cord medicine 2026 Jan;49(1):95-106
The journal of spinal cord medicine 2026 Jan;49(1):95-106
Icariin inhibits autophagy and promotes apoptosis by regulating mitochondrial division in Triple-negative breast cancer.
Wang W, Zhang X, Gao S, Liu J, Jiang S, Meng Q, Zhang H, Li Y, Shi W, Lv Y
Biochemical pharmacology 2026 Jan;243(Pt 2):117549
Biochemical pharmacology 2026 Jan;243(Pt 2):117549
Licochalcone A promotes autophagy to ameliorate NAFLD by inhibiting the mTOR and regulating ULK1/Beclin1/VPS34 pathway.
Li J, Zhang D, Liu P, Fang R, Li Y, Zhu Y, Dong M, Xie S, Liu Y, Wu J, Zhu G, Han J
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120333
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120333
Liraglutide Ameliorates Injury-Related Vascular Repair by Activating Autophagy Through Modulation of the PI3K-mTOR Signaling Pathway.
Zhang Z, Wu G, Xu C, Li S, Zhang Y, Hu Y, Wu W, Ding H, Liu Y, Huang Y, Lu W, Zheng M, Zhang Y, Wu H, Hu L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Jan 15;40(1):e71357
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Jan 15;40(1):e71357
GCN2 activates macrophage autophagy to inhibit NLRP3 inflammasome-mediated acute lung injury.
Xie Y, Chen X, Gong X, Chen H, Xu S
International immunopharmacology 2026 Jan 1;168(Pt 1):115785
International immunopharmacology 2026 Jan 1;168(Pt 1):115785
DNA damage in macrophages drives immune autoreactivity via nuclear antigen presentation.
Niotis G, Arvanitaki ES, Theodorakis E, Schmalen A, Juretschke T, Argyros O, Tsolis KC, Bertsias G, Drakos E, Beli P, Garinis GA
Nature aging 2026 Feb;6(2):393-413
Nature aging 2026 Feb;6(2):393-413
Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress.
Qiu QQ, Zhang N, Xu YY, Qin JW, Yu GF, Song XR
Molecular medicine reports 2026 Feb;33(2)
Molecular medicine reports 2026 Feb;33(2)
Recruitment of CCR5(+) inflammatory monocytes in pulmonary tissue contributes to acute lung injury.
Wei D, Li X, Xu G, Sun Y, Zhu X, Duan Q, Gao N, Dong A, Kong M
Genes and immunity 2026 Feb;27(1):106-116
Genes and immunity 2026 Feb;27(1):106-116
CPNE3 promotes colorectal cancer progression by regulating KIF4-mediated autophagy.
Tang C, Teng W, Jiang Y, Wu Y
Journal of gastrointestinal oncology 2026 Feb 28;17(1):17
Journal of gastrointestinal oncology 2026 Feb 28;17(1):17
Disruption of FGL2 induces TFEB-dependent lysosomal degradation of PD-L1 and enhances the efficacy of anti-PD1 therapy in hepatocellular carcinoma.
Han M, Guan Q, Yan F, Wang M, Xi D, Ning Q
Cell communication and signaling : CCS 2026 Feb 2;24(1)
Cell communication and signaling : CCS 2026 Feb 2;24(1)
VDAC1 protein derived from extracellular vesicles promotes paclitaxel resistance in gastric cancer through autophagy and mitophagy.
Bi Y, Wei S, Zhang Z, Wang Y, Wen Y, Wang H, Li K, Zhang C, Wang Y, Zhao L, Sun G
Cancer biology & medicine 2026 Feb 17;23(2):252-75
Cancer biology & medicine 2026 Feb 17;23(2):252-75
Therapeutic potential of magnesium diboride nanosheets in PAH-associated right heart failure: Integrated multi-omics analysis reveals ferroptosis suppression via LC3/ATG5/NCOA4/FTH1 pathway.
Jiao Q, Yang Y, Xu X, Hao J, Guo J, Wu G, Pang S, Yang W, Zhao Y, Wang L, Wang H, Dong P, Wang Y, Wang T
Free radical biology & medicine 2026 Feb 16;244:1-16
Free radical biology & medicine 2026 Feb 16;244:1-16
An oral-gut microbial metabolite links Fusobacterium nucleatum to aggravated myocardial ischemia-reperfusion injury.
Li Y, Xu Q, Zhu M, Wang W, Liu Y, Yang H, Liu Y
Gut microbes 2026 Dec 31;18(1):2662082
Gut microbes 2026 Dec 31;18(1):2662082
Lactylation of histone H3K18 promotes autophagic gene expression to mitigate immunosuppression in sepsis.
Yang T, Liu S, Jiang Q, Wang N, Zhang L, Shi X, Qiu H, Lu Y, Li WJ, Ni C, Yang J, Zheng J, Zhou H, Li X, Liu X
International journal of biological macromolecules 2026 Apr;358:151667
International journal of biological macromolecules 2026 Apr;358:151667
Multi-omics analysis investigates the mechanisms of plasticizer-induced male reproductive infertility in Northwest China.
Dai W, Sun W, Han H, Ding L, Zhang Z, Si S, Chen Y, Deng Y, Shang Y, Xu B, Pei X, Fu X
Ecotoxicology and environmental safety 2026 Apr 1;314:120076
Ecotoxicology and environmental safety 2026 Apr 1;314:120076
circLOC375190 promotes autophagy through modulation of the mTORC1/TFEB axis in acute ischemic stroke-induced neurological injury.
Liu Q, Zhang L, Xu X
Clinics (Sao Paulo, Brazil) 2025;80:100581
Clinics (Sao Paulo, Brazil) 2025;80:100581
Upregulation of phosphatase and tensin homolog deleted on chromosome ten inhibits lung cancer cell proliferation by suppressing the oncogene polo-like kinase 1 and inducing autophagy.
Jiang W, Wang P, Huang L
CytoJournal 2025;22:10
CytoJournal 2025;22:10
TRIM32 promotes neuronal ferroptosis by enhancing K63-linked ubiquitination and subsequent p62-selective autophagic degradation of GPX4.
Zhou X, Zhao Y, Huang S, Shu H, Zhang Y, Yang H, Ren Y, Zhou X, Liu W, Song T, Zhao J, Ma J
International journal of biological sciences 2025;21(3):1259-1274
International journal of biological sciences 2025;21(3):1259-1274
Suppression of Inflammation by Si Miao San in Experimental Rheumatoid Arthritis Through Modulation of the AKT/ROS/Autophagy Axis.
Zhang H, Jiang H, Wei Q, Xu J, Zhao Z, Sun Y, Lu Q
Journal of inflammation research 2025;18:9459-9476
Journal of inflammation research 2025;18:9459-9476
Paeoniflorin Attenuates Cognitive Dysfunction and Neuroinflammation by Autophagy in Mice with SLE Induced by Imiquimod.
Ma T, Wang Q, Zhang L, Chen X, Fan Z, Wang Y, Zhang X, Huang Y, Lu X, Song P, Xie C, Xi J, Li B, Wang Y
Journal of inflammation research 2025;18:13945-13964
Journal of inflammation research 2025;18:13945-13964
αAsarone alleviates neuronal injury by facilitating autophagy via miR-499-5p/PDCD4/ATG5 signaling pathway in ischemia stroke.
Yan Y, Wu L, Wang L, Wang D, Huang M, Peng J, Huang Y
Frontiers in pharmacology 2025;16:1504683
Frontiers in pharmacology 2025;16:1504683
Fenofibrate suppresses Mycoplasma bovis infection via autophagy-mediated cholesterol regulation in bovine mammary epithelial cells and murine mammary tissue.
Xu M, Wang T, Deng X, Liu Y, Zhu Z, Barkema HW, Cobo ER, Kastelic JP, Zhou X, Han B
Frontiers in cellular and infection microbiology 2025;15:1731492
Frontiers in cellular and infection microbiology 2025;15:1731492
Comparative hepatoprotective effects of AMK and PAMK via Nrf2 signaling in broiler breeders.
Lu B, He J, Pan S, Wei J, Li B, Cao N, Huang Y, Tian Y, Cheong N, Chen Y, Xu D, Li W
Frontiers in veterinary science 2025;12:1672417
Frontiers in veterinary science 2025;12:1672417
PLEKHF1 Induces Mitochondrial Dysfunction to Inhibit Osteosarcoma Growth and Metastasis.
Wan J, Cai X, Liao Z, Liu Y, Liu Q, Zhang C, Long F
IUBMB life 2025 Sep;77(9):e70048
IUBMB life 2025 Sep;77(9):e70048
CDKL3 Targets ATG5 to Exacerbate the Progression of Malignant Melanoma.
Chen Q, Yu W, Gu Y, Cao S, Xie X, Wu L
Molecular carcinogenesis 2025 Sep;64(9):1462-1472
Molecular carcinogenesis 2025 Sep;64(9):1462-1472
Maternal Myo-Inositol Deficiency Involved Autophagy Impairment by PI3K/Akt/mTOR Signaling in Neural Tube Defects During Pregnancy.
Guo J, Chen Z, Yue H, Li S, Sun G, Zhang F, Zhong R, Lyu J, Yang Y, Wang X, Bao Y, Zou J, Guan Z, Zhang T, Wang J
Molecular neurobiology 2025 Sep;62(9):11529-11543
Molecular neurobiology 2025 Sep;62(9):11529-11543
Activation of Sig-1R by afobazole attenuates Tollip/HMGB1-mediaded CCN2 autophagic degradation and NETs formation in sunitinib-induced cardiotoxicity in mice: Involvement of IRE 1α/ASK1/JNK/ AP-1 trajectory.
Shafik MS, El-Tanbouly DM, Bishr A, Soubh AA, Attia AS, Muhammad RN
Toxicology and applied pharmacology 2025 Sep;502:117423
Toxicology and applied pharmacology 2025 Sep;502:117423
Klebsiella pneumoniae Induces Ferroptosis and Lactation Dysfunction in Bovine Mastitis via NCOA4-Mediated Ferritinophagy.
Mao P, Wang Z, Duan J, Dong P, Yuan C, Liu K, Guo L, Cui L, Dong J, Meng X, Zhu G, Li J, Wang H
Journal of agricultural and food chemistry 2025 Sep 24;73(38):24326-24342
Journal of agricultural and food chemistry 2025 Sep 24;73(38):24326-24342
Nitrate Promotes the Survival of Diabetic Skin Flaps by Enhancing Autophagy Through the AMPK Signaling Pathway.
Li M, Zhu L, Xu Y, Han Z
The Journal of craniofacial surgery 2025 Sep 1;36(6):2127-2132
The Journal of craniofacial surgery 2025 Sep 1;36(6):2127-2132
(Z)-Ligustilide alleviates intervertebral disc degeneration by suppressing nucleus pulposus cell pyroptosis via Atg5/NLRP3 axis.
Wang J, Fan C, Zhang Y, Hua D, Ji Z, He W, Deng Y, Geng D, Wu X, Mao H
Science China. Life sciences 2025 Oct;68(10):2965-2981
Science China. Life sciences 2025 Oct;68(10):2965-2981
UBE2D2 promotes gastric cancer progression by inhibiting ferroptosis through autophagy-dependent stabilization of CST1.
Yang Y, Xu J, Zhao Q, Zhang R, Wang Y, Shang C, Pan S, Hu C, Luo C
International journal of biological macromolecules 2025 Oct;327(Pt 2):147333
International journal of biological macromolecules 2025 Oct;327(Pt 2):147333
Dual roles of CXCR4 (C-X-C motif chemokine receptor 4) in promoting entry of ebolavirus and targeting excessive glycoprotein for reticulophagic degradation to facilitate viral fitness.
Huang H, Shi W, Yan H, Fan L, Lu J, Long Z, Li X, Li J, Wang J, Liu L, Qian J
Autophagy 2025 Oct;21(10):2148-2167
Autophagy 2025 Oct;21(10):2148-2167
Perfluorohexane sulfonate (PFHxS) induces liver cytotoxicity by activating autophagy and endoplasmic reticulum stress-regulated mitochondrial pathway apoptosis.
Chen W, Liu S, Zhou Y, Liu B, Wang W, Chen C, Lou Z, Shen XL
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Oct;204:115657
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Oct;204:115657
Yunnan Baiyao regulates Th17/Treg cell homeostasis to inhibit periodontitis through the miR-155-5p/ATG5 pathway.
Zhao R, Chen R, An Y, Liu W, Zheng M, Ma S, Li Y, Ren X, He H
International immunopharmacology 2025 Oct 10;163:115253
International immunopharmacology 2025 Oct 10;163:115253
Decorin Is a Newly Discovered Target of Akkermansia muciniphila in the Treatment of Sepsis-Associated Encephalopathy.
Gong B, Li F, Bai Y, Guo Y, Zhang R, Yu Y, Dong B
CNS neuroscience & therapeutics 2025 Nov;31(11):e70642
CNS neuroscience & therapeutics 2025 Nov;31(11):e70642
SFTSV induces liver ferroptosis through m6A-related ferritinophagy.
Liu B, Tian X, Li L, Jiang N, Cheng M, Zhu J, Wu Z
Autophagy 2025 Nov;21(11):2353-2366
Autophagy 2025 Nov;21(11):2353-2366
Gambogic acid induces ferroptosis and suppresses colorectal cancer progression by modulating the m6A modification of p62.
Wang J, Deng J, Sun B, Qiao G, Yang J, Gao Z, Zhang Q, Dong M, Qu P, Wang Z
Cellular signalling 2025 Nov;135:112024
Cellular signalling 2025 Nov;135:112024
The Composite Antiadhesion Barrier Facilitated Fibroblast Autophagy Activation for Tendon Repair.
Sun Z, Liu J, Chen L, Wang Z, Wang F, Liu S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(41):e06204
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(41):e06204
Mechanisms of Intermittent Theta-Burst Stimulation Upregulates TFEB and Restores Autophagy to Play a Neuroprotective Role in the Acute Phase After Cerebral Ischemia Reperfusion.
Zhang XY, Zhao YN, Gui LH, Han PP, Huang YY, Bi X
Neurochemical research 2025 Nov 27;51(1):4
Neurochemical research 2025 Nov 27;51(1):4
Quercetin ameliorates doxorubicin-induced atrial fibrillation via EGFR-mediated restoration of autophagic flux.
Bian WH, Wang SH, Kang ZC, Xu Y, Li YN, Yang MZ, Yang JH, Liu JY, Cheng YL, Chang D, Xie X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157357
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157357
Quercetin alleviated cadmium-induced oxidative stress, endoplasmic reticulum stress, and autophagy in chicken kidneys.
Shi Y, Yan B, Huang R, Yu W, Xu B, Mao J, Liu Z, Wang J
Environmental pollution (Barking, Essex : 1987) 2025 Nov 15;385:127058
Environmental pollution (Barking, Essex : 1987) 2025 Nov 15;385:127058
TGF-β2 increases eHSP90α secretion via upregulating secretory autophagy pathway.
Li J, Li J, Xie T, Huang S, Tian H, Liu M, Kong X, Zhang D, Nawaz KI, Wang M, Li H, Zhang J, Yuan F, Guo W, Cui X, Mu H, Hu Y
Cell communication and signaling : CCS 2025 Nov 12;23(1):492
Cell communication and signaling : CCS 2025 Nov 12;23(1):492
Regulation of N-degron recognin-mediated autophagy by the SARS-CoV-2 PLpro ubiquitin deconjugase.
Ayala-Torres C, Liu J, Dantuma NP, Masucci MG
Autophagy 2025 May;21(5):1019-1038
Autophagy 2025 May;21(5):1019-1038
Discovery of a potent inhibitor of chaperone-mediated autophagy that targets the HSC70-LAMP2A interaction in non-small cell lung cancer cells.
Dong RF, Qin CJ, Yin Y, Han LL, Xiao CM, Wang KD, Wei RY, Xia YZ, Kong LY
British journal of pharmacology 2025 May;182(10):2287-2309
British journal of pharmacology 2025 May;182(10):2287-2309
Deoxynivalenol-induced pyroptosis and autophagy inhibition collectively promote inflammatory injury in the glandular stomach of chicken embryos.
Chen F, Yang G, Qiu H, Gao S, Hou L, Dong J, Zhao P, Dong W
Poultry science 2025 May;104(5):105052
Poultry science 2025 May;104(5):105052
OTULIN orchestrates NCOA4-FTH1 complex to alleviate APAP-induced hepatocyte Ferroptosis.
Gao L, Chang X, Han Y, Li J, Meng Y, Yang X, Jiang Z
International immunopharmacology 2025 May 8;154:114490
International immunopharmacology 2025 May 8;154:114490
Tspan9 Exacerbates Cardiac Hypertrophy by Impairing Cardiac Autophagy.
Jiang S, Bu S, Kang X, Dong Y, Chen L, Yuan L, Shi M, Du M, Liang M, Huang K, Yang L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70670
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70670
Retroviral foamy virus gag induces parkin-dependent mitophagy.
Wang S, Du T, Yan J, Zheng Y, Tang Y, Wu J, Xu Q, Xu S, Liu L, Chen X, Han S, Yin J, Peng B, He X, Liu W
Retrovirology 2025 May 2;22(1):7
Retrovirology 2025 May 2;22(1):7
Accelerated differentiation of photothermal effect-induced mesenchymal stem cells regulated by activating HSP90-autophagy boosts wound repair.
Li XY, Ding DP, Zhan MY, Ma TQ, Zhao XY, Zheng L, Han N, Leng F, Mao YC, Li Z, Wei W, Tan Y, Tang JM, Li TF
International journal of pharmaceutics 2025 May 15;676:125631
International journal of pharmaceutics 2025 May 15;676:125631
Analysis of the key signaling pathway of baicalin that induces autophagy in papillary thyroid cancer via an optical resonator.
Lai Y, Ru D, Ding C, Wang C, Ding L, Luo C, Qi Y, Chen X, Dai H, Li H
Biomedical optics express 2025 May 1;16(5):1843-1855
Biomedical optics express 2025 May 1;16(5):1843-1855
IGF2BP1-HAX-1 positive feedback loop-mediated HAX-1 overexpression blocks autophagic flux and promotes chemoresistance in nasopharyngeal carcinoma.
Zhang S, Gu M, Yin H, Pan S, Xie H, Chen W, Gul S, Zhao Y, Wang Z, Zheng W, You Y, You B
Cellular and molecular life sciences : CMLS 2025 Mar 7;82(1):105
Cellular and molecular life sciences : CMLS 2025 Mar 7;82(1):105
ATP6AP1 promotes cell proliferation and tamoxifen resistance in luminal breast cancer by inducing autophagy.
Yan Z, Huang A, Ma D, Hong C, Zhang S, He L, Rao H, Luo S
Cell death & disease 2025 Mar 25;16(1):201
Cell death & disease 2025 Mar 25;16(1):201
Polystyrene microplastics induce hepatic lipid metabolism and energy disorder by upregulating the NR4A1-AMPK signaling pathway.
Chiu HW, Chu CW, Huang CC, Chia ZC, Wang YL, Lee YH
Environmental pollution (Barking, Essex : 1987) 2025 Mar 15;369:125850
Environmental pollution (Barking, Essex : 1987) 2025 Mar 15;369:125850
Dicyclohexyl phthalate derails trophoblast function and lipid metabolism through NDRG1 by targeting PPARα:RXRα.
Zhang Y, Geng Y, Zhang Y, Ma Y, Yin X, Chen Z, Mu X, Gao R, Chen X, Li F, He J
Toxicology 2025 Jun;514:154124
Toxicology 2025 Jun;514:154124
Redox regulation of TRIM28 facilitates neuronal ferroptosis by promoting SUMOylation and inhibiting OPTN-selective autophagic degradation of ACSL4.
Liu W, Zhu Y, Ye W, Xiong J, Wang H, Gao Y, Huang S, Zhang Y, Zhou X, Zhou X, Ge X, Cai W, Zheng X
Cell death and differentiation 2025 Jun;32(6):1041-1057
Cell death and differentiation 2025 Jun;32(6):1041-1057
PFOS causes lysosomes-regulated mitochondrial fission through TRPML1-VDAC1 and oligomerization of MCU/ATP5J2.
Yang W, Li Y, Feng R, Liang P, Tian K, Hu L, Wang K, Qiu T, Zhang J, Sun X, Yao X
Journal of hazardous materials 2025 Jun 5;489:137685
Journal of hazardous materials 2025 Jun 5;489:137685
Ergosterol Protects Canine MDCK Cells from Gentamicin-Induced Damage by Modulating Autophagy and Apoptosis.
Qin Z, Xie L, Wang Y, Zhang N, Bi H, Song M, Xu C
Metabolites 2025 Jun 5;15(6)
Metabolites 2025 Jun 5;15(6)
NR4A3 suppresses bladder cancer progression by modulating autophagy via the PI3K/AKT/mTOR pathway.
Fan L, Xu F, Liu S, Wu D, Wang S, Pan X, Zhou Y, Qu L, Zhou W
European journal of histochemistry : EJH 2025 Jun 17;69(3)
European journal of histochemistry : EJH 2025 Jun 17;69(3)
Pomalidomide promotes macrophage control of Mycobacterium tuberculosis via enhancing HDAC6-mediated autophagy.
Zhang F, Dong Y, Yang Z, Guo C, Zhang X, Shang Y, Li L, Gao M, Pang Y
International immunopharmacology 2025 Jun 17;158:114831
International immunopharmacology 2025 Jun 17;158:114831
BNST(GABA) neurons regulate autophagy to alleviate depression with gastric dysfunction symptoms.
Yuan Y, Xu J, Zhu S, Ma H, Wang H, Wang X, Shen G
Brain research bulletin 2025 Jun 15;226:111360
Brain research bulletin 2025 Jun 15;226:111360
Metformin Improves Palmitate-Induced Follicular Granulosa Cell Dysfunction by Activating ULK1-Mediated Autophagy.
Heng N, Hao H, Hu Y, Wang Y, Wang H, He W, Zhu N, Wang R, Xuan X, Zhu H, Zhao S, Wang F
Reproductive sciences (Thousand Oaks, Calif.) 2025 Jul;32(7):2442-2452
Reproductive sciences (Thousand Oaks, Calif.) 2025 Jul;32(7):2442-2452
Transglutaminase 2 promotes breast cancer cell autophagy by targeting p53/ mTOR axis.
Chen J, Li M, Mao J, Wang X, Guo B, Chen X, Kalvakolanu DV, Hong J, Yang M, Liu J, Luo Q, Yang J, Sun X, Tian Y, Zhang L
Biochemical pharmacology 2025 Jul;237:116926
Biochemical pharmacology 2025 Jul;237:116926
HMBOX1 reverses autophagy mediated 5-fluorouracil resistance through promoting HACE1-induced ubiquitination and degradation of ATG5 in colorectal cancer.
Gao Y, Fu S, Peng Y, Zhou Y, Zhu J, Zhang X, Cai C, Han Y, Shen H, Zeng S
Autophagy 2025 Jul;21(7):1556-1577
Autophagy 2025 Jul;21(7):1556-1577
Optimally Aligned Nerve Scaffolds with Sustained Astaxanthin Release Improve the Inflammatory Microenvironment through Mitophagy Activation.
Jin X, Liu S, Fang J, Chen F, Xu B, Nan L, Zhao S, Wu Z, Guan Z, Tao K, Liu J
Small (Weinheim an der Bergstrasse, Germany) 2025 Jul;21(26):e2502939
Small (Weinheim an der Bergstrasse, Germany) 2025 Jul;21(26):e2502939
Inhibiting UPF1 methylation enhances tumor immunotherapy sensitivity by reducing nonsense-mediated mRNA decay.
Zhu S, Bai Y, Zhang D, Huang C, Qian X, Li P, Xie T, Wu Q, Liu A, Zhu T, Yang W, She X, Li M, Rao Z, Chen S, Liu L, Yu C, Liu X, Wang G, Zhang G, Hu J
Cell reports 2025 Jul 22;44(7):115919
Cell reports 2025 Jul 22;44(7):115919
DHX9-mediated epigenetic silencing of BECN1 contributes to impaired autophagy and tumor progression in breast cancer via recruitment of HDAC5.
Li Z, Liu F, Li F, Zeng G, Wen X, Ding J, Zhou J
Cell death & disease 2025 Jul 14;16(1):524
Cell death & disease 2025 Jul 14;16(1):524
USP7 promotes PINK1/Parkin-dependent mitophagy to ameliorate cerebral ischemia-reperfusion injury by deubiquitinating and stabilizing SIRT1.
Hou D, Hu Y, Yun T, Yu D, Yang G
Brain research 2025 Jul 1;1858:149638
Brain research 2025 Jul 1;1858:149638
Bioinformatics analysis and preliminary validation of autophagy-related genes in asthma disease.
Sun B, Huang H, An R, Wei B, Yue X
Scientific reports 2025 Jul 1;15(1):21475
Scientific reports 2025 Jul 1;15(1):21475
Inhibition of ACSS2 triggers glycolysis inhibition and nuclear translocation to activate SIRT1/ATG5/ATG2B deacetylation axis, promoting autophagy and reducing malignancy and chemoresistance in ovarian cancer.
Yang J, Wang H, Li B, Liu J, Zhang X, Wang Y, Peng J, Gao L, Wang X, Hu S, Zhang W, Hong L
Metabolism: clinical and experimental 2025 Jan;162:156041
Metabolism: clinical and experimental 2025 Jan;162:156041
Cyclovirobuxine D inhibits triple-negative breast cancer via YAP/TAZ suppression and activation of the FOXO3a/PINK1-Parkin pathway-induced mitophagy.
Wang ZQ, Wu ZX, Chen JW, Li HF, Wu HD, Bao JX, Cheng Y, Dai YW, Wang OC, Dai XX
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156287
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156287
GYY4137 ameliorates blood brain barrier damage by inhibiting autophagy mediated occludin degradation in cardiac arrest and resuscitation.
Duan P, Li X, Bi Y, Feng W, Jin Z, Zhang X, He G, An D, Wen Z, Zhang B
Scientific reports 2025 Jan 6;15(1):905
Scientific reports 2025 Jan 6;15(1):905
The cholesterol metabolite 25-hydroxycholesterol suppresses porcine deltacoronavirus via lipophagy inhibition and mTORC1 modulation.
Zhang JL, Wang XF, Li JL, Duan C, Wang JF
Veterinary research 2025 Jan 31;56(1):23
Veterinary research 2025 Jan 31;56(1):23
Targeting p38γ synergistically enhances sorafenib-induced cytotoxicity in hepatocellular carcinoma.
Huang C, Zhang C, Li J, Duan Y, Tang Q, Bi F
Cell biology and toxicology 2025 Jan 28;41(1):35
Cell biology and toxicology 2025 Jan 28;41(1):35
Transforming growth factor-β3/Smad2/Smad3 signaling pathway inhibition and autophagy by the Yunpi-Xiefei-Huatan decoction ameliorated airway inflammation and mucus hypersecretion in asthmatic rats.
Wang W, Chen Z, Cui K, Chen N, Gao Q
Journal of ethnopharmacology 2025 Jan 13;339:119125
Journal of ethnopharmacology 2025 Jan 13;339:119125
Autophagic signatures in peripheral blood mononuclear cells from Parkinson's disease patients.
Lee MS, Kim JW, Park DG, Heo H, Kim J, Yoon JH, Chang J
Molecules and cells 2025 Feb;48(2):100173
Molecules and cells 2025 Feb;48(2):100173
HIF-1α/BNIP3-Mediated Endoplasmic Reticulum Degradation via Autophagy Protects Against Ischemia Reperfusion-Induced Acute Kidney Injury.
Zhao H, Yang M, Han Y, Jiang N, Liu Y, Li C, Yang J, Luo S, Liu C, Sun L, Liu F, Liu Y
Antioxidants & redox signaling 2025 Feb;42(4-6):212-227
Antioxidants & redox signaling 2025 Feb;42(4-6):212-227
VANGL2 alleviates inflammatory bowel disease by recruiting the ubiquitin ligase MARCH8 to limit NLRP3 inflammasome activation through OPTN-mediated selective autophagy.
Jiang H, Xie Y, Hu Z, Lu J, Zhang J, Li H, Zeng K, Peng W, Yang C, Huang J, Han Z, Bai X, Yu X
PLoS biology 2025 Feb;23(2):e3002961
PLoS biology 2025 Feb;23(2):e3002961
MLKL-USP7-UBA52 signaling is indispensable for autophagy in brain through maintaining ubiquitin homeostasis.
Zhang Z, Chen S, Jun S, Xu X, Hong Y, Yang X, Zou L, Song YQ, Chen Y, Tu J
Autophagy 2025 Feb;21(2):424-446
Autophagy 2025 Feb;21(2):424-446
PPARβ/δ Activation Improves Corticosterone-Induced Oxidative Stress Damage in Astrocytes by Targeting UBR5/ATM Signaling.
Ji J, Chen YF, Hong C, Ren XW, Xu H, Cai ZY, Dong YF, Sun XL
Journal of neurochemistry 2025 Feb;169(2):e70013
Journal of neurochemistry 2025 Feb;169(2):e70013
Therapeutic effect of dihydroartemisinin on Alzheimer's disease model mice with senile macular degeneration.
Han G, Xuewu G, Meng Z, Yuejing W, Yuchun W, Keshuang Z, Hongbo Y
European journal of medical research 2025 Feb 5;30(1):81
European journal of medical research 2025 Feb 5;30(1):81
Targeting NLRC5 in cardiomyocytes protects postinfarction cardiac injury by enhancing autophagy flux through the CAVIN1/CAV1 axis.
Gu L, Wang S, Zhou L, Wang W, Bao Y, He Y, Yang T, Sun J, Jiang Q, Shan T, Du C, Wang Z, Wang H, Xie L, Gu A, Zhao Y, Ji Y, Wang Q, Wang L
Communications biology 2025 Feb 23;8(1):292
Communications biology 2025 Feb 23;8(1):292
Urolithin A alleviates NLRP3 inflammasome activation and pyroptosis by promoting microglial mitophagy following spinal cord injury.
Chen K, Ying J, Zhu J, Chen L, Liu R, Jing M, Wang Y, Zhou K, Wu L, Wu C, Xiao J, Ni W
International immunopharmacology 2025 Feb 20;148:114057
International immunopharmacology 2025 Feb 20;148:114057
p16(INK4a) promoted progress of MCT induced pulmonary hypertension via maintaining redox balance and autophagy pathway.
Wang F, Xiao W, Li J, Zhang Z, Zhang X, Sun J, Zhong Y, Wang X, Zhuang R, Gu X
Biochemical and biophysical research communications 2025 Feb 16;749:151385
Biochemical and biophysical research communications 2025 Feb 16;749:151385
Apigenin attenuates the atherosclerotic lesions through enhancing selective autophagy/lipophagy and promoting RCT process.
Hu Z, Li Y, Yao N, Gan H, Zeng Q, Huang X, Huang D, Cai D, Chen Y
Pharmaceutical biology 2025 Dec;63(1):387-401
Pharmaceutical biology 2025 Dec;63(1):387-401
HMGB1 impairs nasal mucosa epithelial barrier function in allergic rhinitis by promoting BECN1-mediating autophagy.
Ma Z, Tu L, Yang X, Mao M, Chen G, Chen F, Liao L, Xu Y
Biochemistry and biophysics reports 2025 Dec;44:102351
Biochemistry and biophysics reports 2025 Dec;44:102351
Porcine cGAS-STING signalling induced apoptosis negatively regulates STING downstream IFN response and autophagy via different mechanisms.
Xia N, Liu A, Han H, Jiang S, Cao Q, Luo J, Zhang J, Hao W, Sun Z, Chen N, Zhang H, Zheng W, Zhu J
Virulence 2025 Dec;16(1):2496436
Virulence 2025 Dec;16(1):2496436
Hypoxia-induced secretory autophagy in cancer-associated fibroblasts promotes ECM remodelling through serglycin secretion in oral squamous cell carcinoma.
Zhang Y, Tao C, Yin X, Wang Z, Zhang Y, Yu J, Wang Y, Han W
Clinical and translational medicine 2025 Dec;15(12):e70556
Clinical and translational medicine 2025 Dec;15(12):e70556
Sanggenol L Enhances Temozolomide Drug Sensitivity by Inhibiting Mitophagy and Inducing Apoptosis Through the Regulation of the TRIM16-OPTN Axis in Glioblastoma.
Chang H, Hou J, Hu X, Hou N, Xu M, Du Y, Xu J, Wang Y, Xie Z, Shi J, Zhang Y, Cui H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e02915
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e02915
Targeting FoxO1-STX17-mediated autophagic flux: Quercetin's therapeutic mechanism in diabetic nephropathy.
Hou B, Li Y, Tang J, Cao X, Zhang S, Cai Y, Guo J, Xi J, Wang D, Liu WJ, Lu H
European journal of pharmacology 2025 Dec 5;1008:178309
European journal of pharmacology 2025 Dec 5;1008:178309
Identification of ferroptosis-related genes as diagnostic biomarkers and therapeutic targets in sorafenib-resistant HCC via machine learning and experimental validation.
Zhang J, Geng W, Sun H, Chen J, Fan Y, Tan K
International immunopharmacology 2025 Dec 3;166:115557
International immunopharmacology 2025 Dec 3;166:115557
Ribosome-binding protein 1 maintains peroxisome biogenesis.
Fatima K, Vihinen H, Akpinar A, Somborac T, Paatero A, Jokitalo E, Paavilainen V, Katajisto P, Konovalova S
Journal of cell science 2025 Dec 15;138(24)
Journal of cell science 2025 Dec 15;138(24)
Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restores anti-tumor immunity.
Li Y, Sheng M, Li W, Liu S, Wang B, Liu B, Luo M, Zhou X, Xia Q, Hong S, Zheng Z, Cheng SY, Jiang X, Li J, Huang T
Nature communications 2025 Dec 13;17(1):440
Nature communications 2025 Dec 13;17(1):440
E2F1-autophagy-ALDH1A1 axis enhances self-renewal and drug resistance of lung cancer stem-like cells in a p53-dependent manner.
Li J, Chen Y, Wang J, Liu L, Qadir J, Xie D, Wan X, Luo Y, Xian J, Ye T
Journal of experimental & clinical cancer research : CR 2025 Aug 30;44(1):261
Journal of experimental & clinical cancer research : CR 2025 Aug 30;44(1):261
USP19 potentiates autophagic cell death via inhibiting mTOR pathway through deubiquitinating NEK9 in pancreatic cancer.
Wang G, Dai S, Chen J, Zhang K, Huang C, Zhang J, Xie K, Lin F, Wang H, Gao Y, Yin L, Jiang K, Miao Y, Lu Z
Cell death and differentiation 2025 Apr;32(4):702-713
Cell death and differentiation 2025 Apr;32(4):702-713
Pharmacological targeting of the mitochondrial phosphatase PTPMT1 sensitizes hepatocellular carcinoma to ferroptosis.
Li M, Wang Y, Li X, Xu J, Yan L, Tang S, Liu C, Shi M, Liu R, Zhao Y, Zhang Y, Yang L, Zhang Y, Wang G, Li Z, Guo Y, Feng Y, Liu P
Cell death & disease 2025 Apr 6;16(1):257
Cell death & disease 2025 Apr 6;16(1):257
Progranulin enhances M2 macrophage polarization and renal fibrosis by modulating autophagy in chronic kidney disease.
Tu WC, He YK, Wang DW, Ming SX, Zhao Y
Cellular and molecular life sciences : CMLS 2025 Apr 28;82(1):186
Cellular and molecular life sciences : CMLS 2025 Apr 28;82(1):186
LncRNA HITT inhibits autophagy by attenuating ATG12-ATG5-ATG16L1 complex formation.
Liu H, Wang X, Li B, Xiang Z, Zhao Y, Lu M, Lin Q, Zheng S, Guan T, Zhang Y, Hu Y
Cancer letters 2025 Apr 28;616:217532
Cancer letters 2025 Apr 28;616:217532
Autophagy inhibition enhances antifibrotic potential of placental mesenchymal stem cells of fetal origin via regulating TGF-β1 mediated protein degradation of HGF.
Zhou W, Wang J, Ding L, Cai R, Cheng J, Liang P, Zhu Y, Zhang Z
Scientific reports 2025 Apr 21;15(1):13805
Scientific reports 2025 Apr 21;15(1):13805
Inhibition of anlotinib-induced autophagy attenuates invasion and migration by regulating epithelial-mesenchymal transition and cytoskeletal rearrangement through ATG5 in human osteosarcoma cells.
Zheng B, Sun X, Zhang L, Qu G, Ren C, Yan P, Zhou C, Yue B
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2024;57:e13152
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2024;57:e13152
Metallothionein 3 Potentiates Pulmonary Artery Smooth Muscle Cell Proliferation by Promoting Zinc-MTF1-ATG5 Axis-mediated Autophagosome Formation.
Xiong T, Li Y, Yang M, Huo B, Guo X, Liu L, Huang Y, Zhu X, Hu Q, Wei X, Jiang DS, Yi X
International journal of biological sciences 2024;20(8):2904-2921
International journal of biological sciences 2024;20(8):2904-2921
The PI3K/Akt-Nrf2 Signaling Pathway and Mitophagy Synergistically Mediate Hydroxytyrosol to Alleviate Intestinal Oxidative Damage.
Wen X, Tang S, Wan F, Zhong R, Chen L, Zhang H
International journal of biological sciences 2024;20(11):4258-4276
International journal of biological sciences 2024;20(11):4258-4276
PEI/MMNs@LNA-542 nanoparticles alleviate ICU-acquired weakness through targeted autophagy inhibition and mitochondrial protection.
Wang Y, Xu Y, Zhao T, Ma YJ, Qin W, Hu WL
Open life sciences 2024;19(1):20220952
Open life sciences 2024;19(1):20220952
MicroRNA-204-5p Ameliorates Renal Injury via Regulating Keap1/Nrf2 Pathway in Diabetic Kidney Disease.
Dong J, Liu M, Bian Y, Zhang W, Yuan C, Wang D, Zhou Z, Li Y, Shi Y
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:75-92
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:75-92
Yunnan Baiyao Might Mitigate Periodontitis Bone Destruction by Inhibiting Autophagy and Promoting Osteoblast Differentiation in vivo, ex vivo and in vitro.
Liu W, Li Y, An Y, Zhao R, Wei C, Ren X, He H
Journal of inflammation research 2024;17:2271-2284
Journal of inflammation research 2024;17:2271-2284
Protective effect of naringenin on cadmium chloride-induced renal injury via alleviating oxidative stress, endoplasmic reticulum stress, and autophagy in chickens.
Shi Y, Gao Z, Xu B, Mao J, Wang Y, Liu Z, Wang J
Frontiers in pharmacology 2024;15:1440877
Frontiers in pharmacology 2024;15:1440877
FUNDC1 alleviates doxorubicin-induced cardiotoxicity by restoring mitochondrial-endoplasmic reticulum contacts and blocked autophagic flux.
He W, Sun Z, Tong G, Zeng L, He W, Chen X, Zhen C, Chen P, Tan N, He P
Theranostics 2024;14(9):3719-3738
Theranostics 2024;14(9):3719-3738
Mutant NOTCH3ECD Triggers Defects in Mitochondrial Function and Mitophagy in CADASIL Cell Models.
Wang W, Gong Z, Wang Y, Zhao Y, Lu Y, Sun R, Zhang H, Shang J, Zhang J
Journal of Alzheimer's disease : JAD 2024;100(4):1299-1314
Journal of Alzheimer's disease : JAD 2024;100(4):1299-1314
ONC206 targeting ClpP induces mitochondrial dysfunction and protective autophagy in hepatocellular carcinoma cells.
Cao J, Cao F, Wang C, Jiao Z, You Y, Wang X, Zhao W
Neoplasia (New York, N.Y.) 2024 Sep;55:101015
Neoplasia (New York, N.Y.) 2024 Sep;55:101015
Ferroptosis induced by plasma-activated Ringer's lactate solution prevents oral cancer progression.
Sato K, Yang M, Nakamura K, Tanaka H, Hori M, Nishio M, Suzuki A, Hibi H, Toyokuni S
Oral diseases 2024 Sep;30(6):3912-3924
Oral diseases 2024 Sep;30(6):3912-3924
The p97-UBXD8 complex maintains peroxisome abundance by suppressing pexophagy.
Montes ID, Amirthagunanathan S, Joshi AS, Raman M
bioRxiv : the preprint server for biology 2024 Sep 26;
bioRxiv : the preprint server for biology 2024 Sep 26;
Coxsackievirus group B3 regulates ASS1-mediated metabolic reprogramming and promotes macrophage inflammatory polarization in viral myocarditis.
Liu Q, Shang Y, Tao Z, Li X, Shen L, Zhang H, Liu Z, Rao Z, Yu X, Cao Y, Zeng L, Huang X
Journal of virology 2024 Sep 17;98(9):e0080524
Journal of virology 2024 Sep 17;98(9):e0080524
DMDD, isolated from Averrhoa carambola L., ameliorates diabetic nephropathy by regulating endoplasmic reticulum stress-autophagy crosstalk.
Shi J, Wang Y, Liang T, Wang X, Xie J, Huang R, Xu X, Wei X
Chinese medicine 2024 Sep 12;19(1):125
Chinese medicine 2024 Sep 12;19(1):125
Autophagy aggravates multi-walled carbon nanotube-induced ferroptosis by suppressing PGC-1 dependent-mitochondrial biogenesis in lung epithelial cells.
Zhu L, Zhu D, Ran J, Li M, Lai Z, Zhou Y, Luo L, Liu X, Mao K, Tian K
Chemico-biological interactions 2024 Sep 1;400:111158
Chemico-biological interactions 2024 Sep 1;400:111158
Central role of Sigma-1 receptor in ochratoxin A-induced ferroptosis.
Chen W, Han L, Yang R, Wang H, Yao S, Deng H, Liu S, Zhou Y, Shen XL
Archives of toxicology 2024 Oct;98(10):3323-3336
Archives of toxicology 2024 Oct;98(10):3323-3336
Inflammatory microenvironment of moderate pulpitis enhances the osteo-/odontogenic potential of dental pulp stem cells by autophagy.
Yu S, Liu XM, Liu Y, Tang L, Lei S, Geng C, Yuan Z, Chen X
International endodontic journal 2024 Oct;57(10):1465-1477
International endodontic journal 2024 Oct;57(10):1465-1477
Circadian gene CLOCK accelerates atherosclerosis by promoting endothelial autophagy.
Wang C, Yang X, Guo Z, Zhu G, Fan L
Biotechnology & genetic engineering reviews 2024 Oct;40(2):1230-1245
Biotechnology & genetic engineering reviews 2024 Oct;40(2):1230-1245
Targeting SMYD2 promotes ferroptosis and impacts the progression of pancreatic cancer through the c-Myc/NCOA4 axis-mediated ferritinophagy.
Tan J, Liao S, Yuan B, Liu X, Yu W, Zhan H, Jiang Y, Liu Y
Biochimica et biophysica acta. General subjects 2024 Oct;1868(10):130683
Biochimica et biophysica acta. General subjects 2024 Oct;1868(10):130683
The RNA N6-methyladenosine demethylase FTO regulates ATG5 to inhibit malignant progression of uveal melanoma.
Yang Y, Zhong Y, Chi C, Lin X, Zhu X, Deng X, Liang J, Cheng Y
Journal of proteomics 2024 Oct 30;309:105282
Journal of proteomics 2024 Oct 30;309:105282
Hepatocyte-Specific HuR Protects Against Acetaminophen-Induced Liver Injury in Mice.
Lu L, Chen J, Jiang H, Li N, Li X, Liu Y, Zong C
Journal of cellular and molecular medicine 2024 Nov;28(22):e70246
Journal of cellular and molecular medicine 2024 Nov;28(22):e70246
TBC1D4 antagonizes RAB2A-mediated autophagic and endocytic pathways.
Tian R, Zhao P, Ding X, Wang X, Jiang X, Chen S, Cai Z, Li L, Chen S, Liu W, Sun Q
Autophagy 2024 Nov;20(11):2426-2443
Autophagy 2024 Nov;20(11):2426-2443
Phillyrin promotes autophagosome formation in A53T-αSyn-induced Parkinson's disease model via modulation of REEP1.
Qi LF, Liu Y, Liu S, Xiang L, Liu Z, Liu Q, Zhao JQ, Xu X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155952
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155952
Zosuquidar Promotes Antitumor Immunity by Inducing Autophagic Degradation of PD-L1.
Ding L, Guo H, Zhang J, Zheng M, Zhang W, Wang L, Du Q, Zhou C, Xu Y, Wu H, He Q, Yang B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2400340
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2400340
Ergothioneine ameliorates metabolic dysfunction-Associated Steatotic Liver Disease (MASLD) by enhancing autophagy, inhibiting oxidative damage and inflammation.
Lv X, Nie C, Shi Y, Qiao Q, Gao J, Zou Y, Yang J, Chen L, Hou X
Lipids in health and disease 2024 Nov 28;23(1):395
Lipids in health and disease 2024 Nov 28;23(1):395
Hepatocyte-derived Fetuin-A promotes alcohol-associated liver disease in mice by inhibiting autophagy-lysosome degradation of TLR and M2 macrophage polarization.
Lu S, Jin H, Nong T, Li D, Long K, Chen Y, Li Y, Xing H, Pan T, He S, Jiang K, Zhong F
Free radical biology & medicine 2024 Nov 1;224:506-520
Free radical biology & medicine 2024 Nov 1;224:506-520
Autophagy-related protein 5 (ATG5) interacts with bone marrow stromal cell antigen 2 (BST2) to stimulate HBV replication through antagonizing the antiviral activity of BST2.
Li Q, Wen W, Wang Y, Gong T, Wang X, Tan Q, Fan B, Xie H, Li Y, Li S, Yang C, Zhou Z, Duan X, Lin W, Chen L
Journal of medical virology 2024 May;96(5):e29659
Journal of medical virology 2024 May;96(5):e29659
Combining large-spot low-fluence 1064-nm and fractional 1064-nm picosecond lasers for promoting protective melanosome autophagy via the PI3K/Akt/mTOR signalling pathway for the treatment of melasma.
Shen J, Jin J, Huang J, Guo Y, Qian Q
Experimental dermatology 2024 May;33(5):e15094
Experimental dermatology 2024 May;33(5):e15094
circUSP13 facilitates the fast-to-slow myofiber shift via the MAPK/ERK signaling pathway in goat skeletal muscles.
Zhang Z, Kang Z, Deng K, Li J, Liu Z, Huang X, Wang F, Fan Y
Journal of cellular physiology 2024 May;239(5):e31226
Journal of cellular physiology 2024 May;239(5):e31226
Heme oxygenase 1 (HO1) regulates autophagy and apoptosis via the PI3K/AKT/mTOR signaling pathway of yak Sertoli cells.
Yan Q, Wang Q, Nan J, Chen T, Wang J, Zhang Y, Yuan L
Theriogenology 2024 May;220:96-107
Theriogenology 2024 May;220:96-107
N6-Methyladenosine Modification of lncCCKAR-5 Regulates Autophagy in Human Umbilical Cord Mesenchymal Stem Cells by Destabilizing LMNA and Inhibits Diabetic Wound Healing.
Wang J, Wang X, Chen F, Ning Q, Liu Y, Zhu Y, Wei W, Leng M, Wang Z, Jin P, Li Q
The Journal of investigative dermatology 2024 May;144(5):1148-1160.e15
The Journal of investigative dermatology 2024 May;144(5):1148-1160.e15
miR-155-5p promotes hepatic steatosis via PICALM-mediated autophagy in aging hepatocytes.
Chen X, Lu T, Zheng Y, Lin Z, Liu C, Yuan D, Yuan C
Archives of gerontology and geriatrics 2024 May;120:105327
Archives of gerontology and geriatrics 2024 May;120:105327
Urolithin A Hijacks ERK1/2-ULK1 Cascade to Improve CD8(+) T Cell Fitness for Antitumor Immunity.
Ma S, Wu Q, Wu W, Tian Y, Zhang J, Chen C, Sheng X, Zhao F, Ding L, Wang T, Zhao L, Xie Y, Wang Y, Yue X, Wu Z, Wei J, Zhang K, Liang X, Gao L, Wang H, Wang G, Li C, Ma C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(18):e2310065
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(18):e2310065
Pectinose induces cell cycle arrest in luminal A and triple-negative breast cancer cells by promoting autophagy through activation of the p38 MAPK signaling pathway.
Yu S, Yue Z, Liu Q
BMC cancer 2024 May 24;24(1):639
BMC cancer 2024 May 24;24(1):639
D-arabinose induces cell cycle arrest by promoting autophagy via p38 MAPK signaling pathway in breast cancer.
Tang Z, Song H, Qin S, Tian Z, Zhang C, Zhou Y, Cai R, Zhu Y
Scientific reports 2024 May 16;14(1):11219
Scientific reports 2024 May 16;14(1):11219
Vitamin D Receptor Activation Reduces Hepatic Inflammation via Enhancing Macrophage Autophagy in Cholestatic Mice.
Wen T, Xie J, Ma L, Hao Z, Zhang W, Wu T, Li L
The American journal of pathology 2024 Mar;194(3):369-383
The American journal of pathology 2024 Mar;194(3):369-383
Qingguang'an-induced autophagy in TFs inhibits scar formation: A follow-up in vivo mechanistic investigation.
Hu R, Wang XJ, Chen S, Huang Y, Yu J
Journal of traditional and complementary medicine 2024 Mar;14(2):173-181
Journal of traditional and complementary medicine 2024 Mar;14(2):173-181
Kaempferol improves Pb-induced cognitive impairments via inhibiting autophagy.
Wang M, Xia Y, Ai S, Gu X, Wang HL
The Journal of nutritional biochemistry 2024 Mar;125:109556
The Journal of nutritional biochemistry 2024 Mar;125:109556
Dihydromyricetin ameliorates hepatic steatosis and insulin resistance via AMPK/PGC-1α and PPARα-mediated autophagy pathway.
Yang Y, Qiu W, Xiao J, Sun J, Ren X, Jiang L
Journal of translational medicine 2024 Mar 26;22(1):309
Journal of translational medicine 2024 Mar 26;22(1):309
Co-exposure to polystyrene nanoplastics and triclosan induces synergistic cytotoxicity in human KGN granulosa cells by promoting reactive oxygen species accumulation.
Wang W, Zhou C, Ma Z, Zeng L, Wang H, Cheng X, Zhang C, Xue Y, Yuan Y, Li J, Hu L, Huang J, Luo T, Zheng L
Ecotoxicology and environmental safety 2024 Mar 15;273:116121
Ecotoxicology and environmental safety 2024 Mar 15;273:116121
Effective-components combination alleviates PM2.5-induced inflammation by evoking macrophage autophagy in COPD.
Wang J, He W, Yue H, Zhao P, Li J
Journal of ethnopharmacology 2024 Mar 1;321:117537
Journal of ethnopharmacology 2024 Mar 1;321:117537
FTO demethylates regulates cell-cycle progression by controlling CCND1 expression in luteinizing goat granulosa cells.
Li D, Zhou L, Liu Z, Zhang Z, Mao W, Shi W, Zhu M, Wang F, Wan Y
Theriogenology 2024 Mar 1;216:20-29
Theriogenology 2024 Mar 1;216:20-29
TRIM28-Mediated Excessive Oxidative Stress Induces Cellular Senescence in Granulosa Cells and Contributes to Premature Ovarian Insufficiency In Vitro and In Vivo.
Zhou C, Li D, He J, Luo T, Liu Y, Xue Y, Huang J, Zheng L, Li J
Antioxidants (Basel, Switzerland) 2024 Mar 1;13(3)
Antioxidants (Basel, Switzerland) 2024 Mar 1;13(3)
Senecavirus A induces mitophagy to promote self-replication through direct interaction of 2C protein with K27-linked ubiquitinated TUFM catalyzed by RNF185.
Chen M, Zhang X, Kong F, Gao P, Ge X, Zhou L, Han J, Guo X, Zhang Y, Yang H
Autophagy 2024 Jun;20(6):1286-1313
Autophagy 2024 Jun;20(6):1286-1313
CAPN2 promotes apalutamide resistance in metastatic hormone-sensitive prostate cancer by activating protective autophagy.
Qi Z, Bai X, Wu L, Zhang P, Guo Z, Yu Y
Journal of translational medicine 2024 Jun 6;22(1):538
Journal of translational medicine 2024 Jun 6;22(1):538
TGF β1 promotes the polarization of M2-type macrophages and activates PI3K/mTOR signaling pathway by inhibiting ISG20 to sensitize ovarian cancer to cisplatin.
Wu J, Jiang L, Wang S, Peng L, Zhang R, Liu Z
International immunopharmacology 2024 Jun 15;134:112235
International immunopharmacology 2024 Jun 15;134:112235
Lycorine attenuated proliferation and induced apoptosis on imatinib-resistant K562 cell by inhibiting autophagy.
Bai J, Feng Z, Chen Y, Li Y, Zhang L, Li L
Discover oncology 2024 Jun 10;15(1):217
Discover oncology 2024 Jun 10;15(1):217
ENO1 contributes to the gemcitabine resistance of pancreatic cancer through the YAP1 signaling pathway.
Ma H, Kong L, Liu L, Du Y, Zhu X, Wang J, Zhao W
Molecular carcinogenesis 2024 Jul;63(7):1221-1234
Molecular carcinogenesis 2024 Jul;63(7):1221-1234
Fibroblast growth factor 21 alleviates idiopathic pulmonary fibrosis by inhibiting PI3K-AKT-mTOR signaling and stimulating autophagy.
Qi J, Wu Y, Guo Z, Zhu S, Xiong J, Hu F, Liang X, Ye X
International journal of biological macromolecules 2024 Jul;273(Pt 1):132896
International journal of biological macromolecules 2024 Jul;273(Pt 1):132896
Exploring the Molecular Mechanism of Schisandrin C for the Treatment of Atherosclerosis via the PI3K/AKT/mTOR Autophagy Pathway.
Duan H, Li H, Liu T, Chen Y, Luo M, Shi Y, Zhou J, Rashed MMA, Zhai K, Li L, Wei Z
ACS omega 2024 Jul 30;9(30):32920-32930
ACS omega 2024 Jul 30;9(30):32920-32930
DKK1 loss promotes endometrial fibrosis via autophagy and exosome-mediated macrophage-to-myofibroblast transition.
Zhang Z, Hu J
Journal of translational medicine 2024 Jul 3;22(1):617
Journal of translational medicine 2024 Jul 3;22(1):617
Zearalenone modulates the function of goat endometrial cells via the mitochondrial quality control system.
Zhang G, Zeng C, Sun X, Zhang Q, Wang Y, Xia R, Mai Q, Xue G, Huang H, Wang F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23701
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23701
Combination of mangiferin and T0901317 targeting autophagy promotes cholesterol efflux from macrophage foam cell in atherosclerosis.
Chen Q, Wang S, Bao R, Wang D, Wu Y, Zhang Y, Liu M, Wang T
Chinese medicine 2024 Jan 5;19(1):5
Chinese medicine 2024 Jan 5;19(1):5
Diterpenoid WT-29 isolated from Wedelia exerted anti-inflammatory and anti-allergic activities.
Wang R, Zeng J, Chen L, Sun L, Wang Y, Xu J, He X
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117265
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117265
Antioxidative Sirt1 and the Keap1-Nrf2 Signaling Pathway Impair Inflammation and Positively Regulate Autophagy in Murine Mammary Epithelial Cells or Mammary Glands Infected with Streptococcus uberis.
Khan S, Wang T, Cobo ER, Liang B, Khan MA, Xu M, Qu W, Gao J, Barkema HW, Kastelic JP, Liu G, Han B
Antioxidants (Basel, Switzerland) 2024 Jan 29;13(2)
Antioxidants (Basel, Switzerland) 2024 Jan 29;13(2)
Liensinine alleviates mouse intestinal injury induced by sepsis through inhibition of oxidative stress, inflammation, and cell apoptosis.
Wang G, Ma F, Xie K, Li X, Tan X, Xia Y, Wang Y, Dong J
International immunopharmacology 2024 Jan 25;127:111335
International immunopharmacology 2024 Jan 25;127:111335
Phomopsterone B Alleviates Liver Fibrosis through mTOR-Mediated Autophagy and Apoptosis Pathway.
Peng ML, Zhang LJ, Luo Y, Xu SY, Long XM, Ao JL, Liao SG, Zhu QF, He X, Xu GB
Molecules (Basel, Switzerland) 2024 Jan 15;29(2)
Molecules (Basel, Switzerland) 2024 Jan 15;29(2)
Fluorochloridone induces mitochondrial dysfunction and apoptosis in primary goat Sertoli cells.
Li Y, Li L, Xiong W, Duan X, Xi H
Theriogenology 2024 Jan 15;214:192-200
Theriogenology 2024 Jan 15;214:192-200
ATF4/PHGDH mediates the effects of ER stress on cadmium-induced autophagy and glycolysis.
Yang Y, Li S, Yang Y, Li Q, Liu Y, Cao J
Toxicology 2024 Dec;509:153976
Toxicology 2024 Dec;509:153976
m6A reader YTHDC2 mediates NCOA4 mRNA stability affecting ferritinophagy to alleviate secondary injury after intracerebral haemorrhage.
Li F, Wang F, Wang L, Wang J, Wei S, Meng J, Li Y, Feng L, Jiang P
Epigenetics 2024 Dec;19(1):2326868
Epigenetics 2024 Dec;19(1):2326868
Mycobacterium manipulate glutaminase 1 mediated glutaminolysis to regulate macrophage autophagy for bacteria intracellular survival.
Yu J, Yan N, Gong Z, Ma Q, Liu J, Wu X, Deng G
Cellular signalling 2024 Dec;124:111422
Cellular signalling 2024 Dec;124:111422
Taxifolin attenuates hepatic ischemia-reperfusion injury by enhancing PINK1/Parkin-mediated mitophagy.
Zhang R, Fang Q, Yao L, Yu X, Liu X, Zhan M, Liu D, Yan Q, Du J, Chen L
European journal of pharmacology 2024 Dec 15;985:177100
European journal of pharmacology 2024 Dec 15;985:177100
Autophagy-mediated activation of the AIM2 inflammasome enhances M1 polarization of microglia and exacerbates retinal neovascularization.
Liu X, Zhou Q, Meng J, Zuo H, Li R, Zhang R, Lu H, Zhang Z, Li H, Zeng S, Tian M, Wang H, Hu K, Li N, Mao L, Hou S
MedComm 2024 Aug;5(8):e668
MedComm 2024 Aug;5(8):e668
Icariin Ameliorates D-galactose-induced Cell Injury in Neuron-like PC12 Cells by Inhibiting MPTP Opening.
Hu SS, Wang TY, Ni L, Hu FX, Yue BW, Zheng Y, Wang TL, Kumar A, Wang YY, Wang JE, Zhou ZY
Current medical science 2024 Aug;44(4):748-758
Current medical science 2024 Aug;44(4):748-758
Hepatoprotective effect of dietary pterostilbene against high-fat-diet-induced lipid accumulation exacerbated by chronic jet lag via SIRT1 and SIRT3 activation.
Koh YC, Yao CH, Lee PS, Nagabhushanam K, Ho CT, Pan MH
Phytotherapy research : PTR 2024 Aug;38(8):4099-4113
Phytotherapy research : PTR 2024 Aug;38(8):4099-4113
The heat shock protein DNAJB8 inhibits pseudorabies virus replication by autophagy.
Chen X, Li W
Veterinary microbiology 2024 Aug;295:110165
Veterinary microbiology 2024 Aug;295:110165
Targeting Rab7-Rilp Mediated Microlipophagy Alleviates Lipid Toxicity in Diabetic Cardiomyopathy.
Ke J, Pan J, Lin H, Huang S, Zhang J, Wang C, Chang ACY, Gu J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(29):e2401676
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(29):e2401676
Colchicine-mediated selective autophagic degradation of HBV core proteins inhibits HBV replication and HBV-related hepatocellular carcinoma progression.
Zhang H, Su X, Gu L, Tan M, Liu Y, Xu K, Ren J, Chen J, Li Z, Cheng S
Cell death discovery 2024 Aug 6;10(1):352
Cell death discovery 2024 Aug 6;10(1):352
Synthetic lethality of combined ULK1 defection and p53 restoration induce pyroptosis by directly upregulating GSDME transcription and cleavage activation through ROS/NLRP3 signaling.
Chen W, Yang KB, Zhang YZ, Lin ZS, Chen JW, Qi SF, Wu CF, Feng GK, Yang DJ, Chen M, Zhu XF, Li X
Journal of experimental & clinical cancer research : CR 2024 Aug 30;43(1):248
Journal of experimental & clinical cancer research : CR 2024 Aug 30;43(1):248
Cetylpyridinium chloride triggers paraptosis to suppress pancreatic tumor growth via the ERN1-MAP3K5-p38 pathway.
Tang H, Chen F, Gao W, Cai X, Lin Z, Kang R, Tang D, Liu J
iScience 2024 Aug 16;27(8):110598
iScience 2024 Aug 16;27(8):110598
Yunnan Baiyao Inhibits Periodontitis by Suppressing the Autophagic Flux.
Li Y, Liu W, Zhao R, An Y, Zhang M, Ren X, He H
International dental journal 2024 Apr;74(2):284-293
International dental journal 2024 Apr;74(2):284-293
Breast cancer cells have an increased ferroptosis risk induced by system x(c)(-) blockade after deliberately downregulating CYTL1 to mediate malignancy.
Xue W, Yu Y, Yao Y, Zhou L, Huang Y, Wang Y, Chen Z, Wang L, Li X, Wang X, Du R, Shen Y, Xu Q
Redox biology 2024 Apr;70:103034
Redox biology 2024 Apr;70:103034
GBP2 enhances paclitaxel sensitivity in triple‑negative breast cancer by promoting autophagy in combination with ATG2 and inhibiting the PI3K/AKT/mTOR pathway.
Zhang W, Tang X, Peng Y, Xu Y, Liu L, Liu S
International journal of oncology 2024 Apr;64(4)
International journal of oncology 2024 Apr;64(4)
Polyvinyl alcohol/carboxymethyl chitosan-based hydrogels loaded with taxifolin liposomes promote diabetic wound healing by inhibiting inflammation and regulating autophagy.
Ding Q, Liu X, Liu X, Chai G, Wang N, Ma S, Zhang L, Zhang S, Yang J, Wang Y, Shen L, Ding C, Liu W
International journal of biological macromolecules 2024 Apr;263(Pt 1):130226
International journal of biological macromolecules 2024 Apr;263(Pt 1):130226
Corynoxine triggers cell death via activating PP2A and regulating AKT-mTOR/GSK3β axes in NSCLC.
Hou G, Hu W, Sang Y, Gan X, Xu H, Hu Q, Cao X
Biochemical pharmacology 2024 Apr;222:116110
Biochemical pharmacology 2024 Apr;222:116110
Dexamethasone upregulates macrophage PIEZO1 via SGK1, suppressing inflammation and increasing ROS and apoptosis.
Liu H, Zhou L, Wang X, Zheng Q, Zhan F, Zhou L, Dong Y, Xiong Y, Yi P, Xu G, Hua F
Biochemical pharmacology 2024 Apr;222:116050
Biochemical pharmacology 2024 Apr;222:116050
Tris-Functionalized Polyoxotungstovanadate-Mediated Antitumor Efficacy Involves Multiple Cell Death Pathways.
Chen L, Zhao Z, Diarimalala RO, Chen Z, Wang Y, Zhan T, Zhao Y, Ma C, Wang X, Zhao C, Xiao Z, Hu K, Wu P
Chemistry & biodiversity 2024 Apr;21(4):e202301898
Chemistry & biodiversity 2024 Apr;21(4):e202301898
Selenomethionine Inhibits NF-κB-mediated Inflammatory Responses of Bovine Mammary Epithelial Cells Caused by Klebsiella pneumoniae by Increasing Autophagic Flux.
Xu S, Miao Y, Dong J, Cui L, Liu K, Li J, Meng X, Zhu G, Wang H
Biological trace element research 2024 Apr;202(4):1568-1581
Biological trace element research 2024 Apr;202(4):1568-1581
Ginsenoside Rk1 induces autophagy-dependent apoptosis in hepatocellular carcinoma by AMPK/mTOR signaling pathway.
Wu H, Qu L, Bai X, Zhu C, Liu Y, Duan Z, Liu H, Fu R, Fan D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114587
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Apr;186:114587
Myricetin Oligomer Triggers Multi-Receptor Mediated Penetration and Autophagic Restoration of Blood-Brain Barrier for Ischemic Stroke Treatment.
Liu L, Ma Z, Han Q, Meng W, Wang H, Guan X, Shi Q
ACS nano 2024 Apr 9;18(14):9895-9916
ACS nano 2024 Apr 9;18(14):9895-9916
Suppression of hypoxia-induced CAV1 autophagic degradation enhances nanoalbumin-paclitaxel transcytosis and improves therapeutic activity in pancreatic cancer.
Bai X, Xiong J, Li L, Yu C, Sun C
European journal of pharmacology 2024 Apr 15;969:176431
European journal of pharmacology 2024 Apr 15;969:176431
PM2.5 exposure-induced senescence-associated secretory phenotype in airway smooth muscle cells contributes to airway remodeling.
Cheng PP, Yu F, Chen SJ, Feng X, Jia ZH, Hu SH, Cui XL, Zhou YY, Niu Q, Liang LM, Wang M, Song LJ, He XL, Xiong L, Xiang F, Wang X, Ma WL, Ye H
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123674
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123674
Lycium barbarum Polysaccharides Regulating miR-181/Bcl-2 Decreased Autophagy of Retinal Pigment Epithelium with Oxidative Stress.
Yang YJ, Wang Y, Deng Y, Liu XQ, Lu J, Peng J, Li J, Zhou YS, Zhu HA, Li B, Qin YH, Peng QH
Oxidative medicine and cellular longevity 2023;2023:9554457
Oxidative medicine and cellular longevity 2023;2023:9554457
Inhibition of TRF2 Leads to Ferroptosis, Autophagic Death, and Apoptosis by Causing Telomere Dysfunction.
Yang Q, Nie Z, Zhu Y, Hao M, Liu S, Ding X, Wang F, Wang F, Geng X
Oxidative medicine and cellular longevity 2023;2023:6897268
Oxidative medicine and cellular longevity 2023;2023:6897268
P16(INK4a) Regulates ROS-Related Autophagy and CDK4/6-Mediated Proliferation: A New Target of Myocardial Regeneration Therapy.
Sun J, Zhou L, Yang T, Deng B, Bao Y, Gu L, Wang H, Wang L
Oxidative medicine and cellular longevity 2023;2023:1696190
Oxidative medicine and cellular longevity 2023;2023:1696190
TNFR2 deficiency impairs the growth of mouse colon cancer.
Li P, Yang Y, Yang X, Wang Y, Chou CK, Jiang M, Zheng J, Chen F, Chen X
International journal of biological sciences 2023;19(4):1024-1035
International journal of biological sciences 2023;19(4):1024-1035
Vitamin D Receptor Activation Targets ROS-Mediated Crosstalk Between Autophagy and Apoptosis in Hepatocytes in Cholestasic Mice.
Zheng Z, Xie J, Ma L, Hao Z, Zhang W, Li L
Cellular and molecular gastroenterology and hepatology 2023;15(4):887-901
Cellular and molecular gastroenterology and hepatology 2023;15(4):887-901
Aspirin-triggered Resolvin D1 ameliorates activation of the NLRP3 inflammasome via induction of autophagy in a rat model of neuropathic pain.
Wang YH, Tang YR, Gao X, Zhang NN, Lv QQ, Liu J, Li Y
Frontiers in pharmacology 2023;14:971136
Frontiers in pharmacology 2023;14:971136
A new insight of cadmium-induced cellular evidence of autophagic-associated spermiophagy during spermatogenesis.
Ali W, Deng K, Sun J, Ma Y, Liu Z, Zou H
Environmental science and pollution research international 2023 Sep;30(45):101064-101074
Environmental science and pollution research international 2023 Sep;30(45):101064-101074
Elsinochrome A induces cell apoptosis and autophagy in photodynamic therapy.
Yao Y, Pan L, Song W, Yuan Y, Yan S, Yu S, Chen S
Journal of cellular biochemistry 2023 Sep;124(9):1346-1365
Journal of cellular biochemistry 2023 Sep;124(9):1346-1365
Macrophage migration inhibitory factor exacerbates asthmatic airway remodeling via dynamin-related protein 1-mediated autophagy activation.
Liu J, Chen Y, Chen H, Wang Y, Li D, Zhang Q, Chai L, Qiu Y, Zhang J, Shen N, Wang Q, Wang J, Li M
Respiratory research 2023 Sep 6;24(1):216
Respiratory research 2023 Sep 6;24(1):216
Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) alleviate excessive autophagy of ovarian granular cells through VEGFA/PI3K/AKT/mTOR pathway in premature ovarian failure rat model.
Dai W, Yang H, Xu B, He T, Liu L, Ma X, Ma J, Yang G, Si R, Pei X, Du X, Fu X
Journal of ovarian research 2023 Sep 30;16(1):198
Journal of ovarian research 2023 Sep 30;16(1):198
Cancer/testis antigen CAGE mediates osimertinib resistance in non-small cell lung cancer cells and predicts poor prognosis in patients with pulmonary adenocarcinoma.
Yeon M, Lee H, Yeo J, Jeong MS, Jung HS, Lee H, Shim K, Jo H, Jeon D, Koh J, Jeoung D
Scientific reports 2023 Sep 21;13(1):15748
Scientific reports 2023 Sep 21;13(1):15748
Co-exposure to environmentally relevant concentrations of cadmium and polystyrene nanoplastics induced oxidative stress, ferroptosis and excessive mitophagy in mice kidney.
Qiu W, Ye J, Su Y, Zhang X, Pang X, Liao J, Wang R, Zhao C, Zhang H, Hu L, Tang Z, Su R
Environmental pollution (Barking, Essex : 1987) 2023 Sep 15;333:121947
Environmental pollution (Barking, Essex : 1987) 2023 Sep 15;333:121947
Streptococcus uberis induced expressions of pro-inflammatory IL-6, TNF-α, and IFN-γ in bovine mammary epithelial cells associated with inhibited autophagy and autophagy flux formation.
Khan S, Yang J, Cobo ER, Wang Y, Xu M, Wang T, Shi Y, Liu G, Han B
Microbial pathogenesis 2023 Oct;183:106270
Microbial pathogenesis 2023 Oct;183:106270
Anti-rheumatoid arthritis effects of total saponins from Rhizoma Panacis Majoris on adjuvant-induced arthritis in rats and rheumatoid arthritis fibroblast-like synoviocytes.
Ren M, Ma K, Pang X, Liu Y, Song Z, Zhou R, Tang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155021
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:155021
SETDB1 Methylates MCT1 Promoting Tumor Progression by Enhancing the Lactate Shuttle.
She X, Wu Q, Rao Z, Song D, Huang C, Feng S, Liu A, Liu L, Wan K, Li X, Yu C, Qiu C, Luo X, Hu J, Wang G, Xu F, Sun L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(28):e2301871
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(28):e2301871
CL4-modified exosomes deliver lncRNA DARS-AS1 siRNA to suppress triple-negative breast cancer progression and attenuate doxorubicin resistance by inhibiting autophagy.
Liu X, Zhang G, Yu T, Liu J, Chai X, Yin D, Zhang C
International journal of biological macromolecules 2023 Oct 1;250:126147
International journal of biological macromolecules 2023 Oct 1;250:126147
Ligustrazine and liguzinediol protect against doxorubicin-induced cardiomyocytes injury by inhibiting mitochondrial apoptosis and autophagy.
Lian N, Tong J, Zhu W, Meng Q, Jiang M, Bian M, Li Y
Clinical and experimental pharmacology & physiology 2023 Nov;50(11):867-877
Clinical and experimental pharmacology & physiology 2023 Nov;50(11):867-877
Bilirubin impacts microglial autophagy via the Akt-mTOR signaling pathway.
Li L, Li S, Pan Z, Zhang Y, Hua Z
Journal of neurochemistry 2023 Nov;167(4):582-599
Journal of neurochemistry 2023 Nov;167(4):582-599
ATAD1 inhibits hepatitis C virus infection by removing the viral TA-protein NS5B from mitochondria.
Zhou Q, Yang Y, Xu Z, Deng K, Zhang Z, Hao J, Li N, Wang Y, Wang Z, Chen H, Yang Y, Xiao F, Zhang X, Gao S, Li YP
EMBO reports 2023 Nov 6;24(11):e56614
EMBO reports 2023 Nov 6;24(11):e56614
Inhibiting autophagy to boost antitumor immunity with tetramethylpyrazine-loaded and PD-L1-targeting liposomal nanoparticles.
Zhou F, Li X, Jia K, Li F, Xue X, Liu J, Qu J, Liu R
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2023 Nov 1;190:106581
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2023 Nov 1;190:106581
Lipid phosphatase SAC1 suppresses hepatitis B virus replication through promoting autophagic degradation of virions.
Zheng J, Deng Y, Wei Z, Zou H, Wen X, Cai J, Zhang S, Jia B, Lu M, Lu K, Lin Y
Antiviral research 2023 May;213:105601
Antiviral research 2023 May;213:105601
Ambra1 modulates the sensitivity of mantle cell lymphoma to palbociclib by regulating cyclin D1.
Jiang Z, Zhang A, Wei W, Li S
Scientific reports 2023 May 24;13(1):8389
Scientific reports 2023 May 24;13(1):8389
Role of nuclear factor of activated T Cells-1 in Sepsis-induced behavioral deficits in mice.
Jiang F, Guo Y, Hu L, Zhang M, Meng J, Si Y, Shi H
Brain research 2023 May 1;1806:148299
Brain research 2023 May 1;1806:148299
RAB7A GTPase Is Involved in Mitophagosome Formation and Autophagosome-Lysosome Fusion in N2a Cells Treated with the Prion Protein Fragment 106-126.
Li Z, Lai M, Li J, Yang D, Zhao M, Wang D, Sun Z, Wen P, Gou F, Dai Y, Ji Y, Zhao D, Qiao J, Yang L
Molecular neurobiology 2023 Mar;60(3):1391-1407
Molecular neurobiology 2023 Mar;60(3):1391-1407
Effects of icariin and curcumol on autophagy, ferroptosis, and lipid metabolism based on miR-7/m-TOR/SREBP1 pathway on prostate cancer.
Xu W, Ding J, Li B, Sun T, You X, He Q, Sheng W
BioFactors (Oxford, England) 2023 Mar;49(2):438-456
BioFactors (Oxford, England) 2023 Mar;49(2):438-456
Neuroprotective effect of Vesatolimod in an experimental autoimmune encephalomyelitis mice model.
Jiang X, Song Y, Fang J, Yang X, Mu S, Zhang J
International immunopharmacology 2023 Mar;116:109717
International immunopharmacology 2023 Mar;116:109717
Inhibition of TRADD ameliorates chondrocyte necroptosis and osteoarthritis by blocking RIPK1-TAK1 pathway and restoring autophagy.
Sun K, Guo Z, Zhang J, Hou L, Liang S, Lu F, Wang G, Xu J, Zhang X, Guo F, Zhu W
Cell death discovery 2023 Mar 31;9(1):109
Cell death discovery 2023 Mar 31;9(1):109
TFEB coordinates autophagy and pyroptosis as hepatotoxicity responses to ZnO nanoparticles.
Pei X, Liu D, Li J, Li L, Ding X, Zhang W, Li Z, Xu G, Li C, Li D
The Science of the total environment 2023 Mar 20;865:161242
The Science of the total environment 2023 Mar 20;865:161242
Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy.
Jiang Y, Zhou Y, Xu W, Wang X, Jin H, Bao X, Lu C
Cell biology and toxicology 2023 Jun;39(3):729-749
Cell biology and toxicology 2023 Jun;39(3):729-749
Neuro death through autophagy via the acetylation of FoxO1 by SIRT2 in the hippocampus of mice in a autism spectrum disorder mice model.
Guo L, Jiang ZM, Zhan YJ, Pan W, Wu QW, Song FX, Zhou X, Zhou XY, Liu LJ, Wang JT
Journal of cellular physiology 2023 Jun;238(6):1275-1287
Journal of cellular physiology 2023 Jun;238(6):1275-1287
VANGL2 inhibits antiviral IFN-I signaling by targeting TBK1 for autophagic degradation.
Hu Z, Xie Y, Lu J, Yang J, Zhang J, Jiang H, Li H, Zhang Y, Wu D, Zeng K, Bai X, Yu X
Science advances 2023 Jun 23;9(25):eadg2339
Science advances 2023 Jun 23;9(25):eadg2339
SIRT3-mediated autophagy contributes to ferroptosis-induced anticancer by inducing the formation of BECN1-SLC7A11 complex.
Huang P, Zhao H, Pan X, Li J, Pan W, Dai H, Wang J, Xia C, Liu F
Biochemical pharmacology 2023 Jul;213:115592
Biochemical pharmacology 2023 Jul;213:115592
Cassiae Semen improves non-alcoholic fatty liver disease through autophagy-related pathway.
Ding M, Zhou F, Li Y, Liu C, Gu Y, Wu J, Fan G, Li Y, Li X
Chinese herbal medicines 2023 Jul;15(3):421-429
Chinese herbal medicines 2023 Jul;15(3):421-429
Recombinant humanized collagen type III with high antitumor activity inhibits breast cancer cells autophagy, proliferation, and migration through DDR1.
Liu X, Li H, Wang T, Yang T, Yang X, Guo K, Hu L, Ming J
International journal of biological macromolecules 2023 Jul 15;243:125130
International journal of biological macromolecules 2023 Jul 15;243:125130
6-Methoxydihydrosanguinarine induces apoptosis and autophagy in breast cancer MCF-7 cells by accumulating ROS to suppress the PI3K/AKT/mTOR signaling pathway.
Zhang L, Zhang X, Che D, Zeng L, Zhang Y, Nan K, Zhang X, Zhang H, Guo Z
Phytotherapy research : PTR 2023 Jan;37(1):124-139
Phytotherapy research : PTR 2023 Jan;37(1):124-139
5'-tRF-GlyGCC promotes breast cancer metastasis by increasing fat mass and obesity-associated protein demethylase activity.
Chen F, Song C, Meng F, Zhu Y, Chen X, Fang X, Ma D, Wang Y, Zhang C
International journal of biological macromolecules 2023 Jan 31;226:397-409
International journal of biological macromolecules 2023 Jan 31;226:397-409
Purvalanol A induces apoptosis and reverses cisplatin resistance in ovarian cancer.
Zhang X, Hong S, Yang J, Liu J, Wang Y, Peng J, Wang H, Hong L
Anti-cancer drugs 2023 Jan 1;34(1):29-43
Anti-cancer drugs 2023 Jan 1;34(1):29-43
MALAT1-miR-30c-5p-CTGF/ATG5 axis regulates silica-induced experimental silicosis by mediating EMT in alveolar epithelial cells.
Xia J, Tian Y, Shao Z, Li C, Ding M, Qi Y, Xu X, Dai K, Wu C, Yao W, Hao C
Ecotoxicology and environmental safety 2023 Jan 1;249:114392
Ecotoxicology and environmental safety 2023 Jan 1;249:114392
Impaired autophagy flux by lncRNA NEAT1 is critical for inflammation factors production in human periodontal ligament stem cells with nicotine treatment.
Zhang T, Yang K, Chen Y, Jiang Y, Zhou Z, Liu J, Du Y, Wang L, Han X, Wu X, Wang X
Journal of periodontal research 2023 Feb;58(1):70-82
Journal of periodontal research 2023 Feb;58(1):70-82
Stimulation of Hepatic Ferritinophagy Mitigates Irp2 Depletion-Induced Anemia.
Liu Y, Li Y, Yang L, Shen J, Zhao H, Dong W, Chang Y, Qiao T, Li K
Antioxidants (Basel, Switzerland) 2023 Feb 24;12(3)
Antioxidants (Basel, Switzerland) 2023 Feb 24;12(3)
BMAL1/p53 mediating bronchial epithelial cell autophagy contributes to PM2.5-aggravated asthma.
Chen SJ, Huang Y, Yu F, Feng X, Zheng YY, Li Q, Niu Q, Jiang YH, Zhao LQ, Wang M, Cheng PP, Song LJ, Liang LM, He XL, Xiong L, Xiang F, Wang X, Ma WL, Ye H
Cell communication and signaling : CCS 2023 Feb 20;21(1):39
Cell communication and signaling : CCS 2023 Feb 20;21(1):39
Isovitexin alleviates hepatic fibrosis by regulating miR-21-mediated PI3K/Akt signaling and glutathione metabolic pathway: based on transcriptomics and metabolomics.
Huang Y, Luo W, Chen S, Su H, Zhu W, Wei Y, Qiu Y, Long Y, Shi Y, Wei J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155117
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155117
Hepatotoxicity of the Pesticide Avermectin Exposure to Freshwater-Farmed Carp: Evidence from In Vivo and In Vitro Research.
Xin Y, Zhang T, Zhou M, Li X, Ping K, Ji X, Yang H, Dong J
Journal of agricultural and food chemistry 2023 Dec 27;71(51):20654-20670
Journal of agricultural and food chemistry 2023 Dec 27;71(51):20654-20670
KPNA2 suppresses porcine epidemic diarrhea virus replication by targeting and degrading virus envelope protein through selective autophagy.
Gao Q, Weng Z, Feng Y, Gong T, Zheng X, Zhang G, Gong L
Journal of virology 2023 Dec 21;97(12):e0011523
Journal of virology 2023 Dec 21;97(12):e0011523
Didymin alleviates metabolic dysfunction-associated fatty liver disease (MAFLD) via the stimulation of Sirt1-mediated lipophagy and mitochondrial biogenesis.
Yang JW, Zou Y, Chen J, Cui C, Song J, Yang MM, Gao J, Hu HQ, Xia LQ, Wang LM, Lv XY, Chen L, Hou XG
Journal of translational medicine 2023 Dec 19;21(1):921
Journal of translational medicine 2023 Dec 19;21(1):921
Thymoquinone induces apoptosis and protective autophagy in gastric cancer cells by inhibiting the PI3K/Akt/mTOR pathway.
He P, He Y, Ma J, Liu Y, Liu C, Baoping Y, Dong W
Phytotherapy research : PTR 2023 Aug;37(8):3467-3480
Phytotherapy research : PTR 2023 Aug;37(8):3467-3480
NLRC5 restricts dengue virus infection by promoting the autophagic degradation of viral NS3 through E3 ligase CUL2 (cullin 2).
Hao J, Li J, Zhang Z, Yang Y, Zhou Q, Wu T, Chen T, Wu Z, Zhang P, Cui J, Li YP
Autophagy 2023 Apr;19(4):1332-1347
Autophagy 2023 Apr;19(4):1332-1347
A Novel Tri-Functional Liposome Re-Educates "Cold Tumor" and Abrogates Tumor Growth by Synergizing Autophagy Inhibition and PD-L1 Blockade.
Zhou F, Li X, Xue X, Li S, Fan G, Cai Y, Chang Z, Qu J, Liu R
Advanced healthcare materials 2023 Apr;12(11):e2202757
Advanced healthcare materials 2023 Apr;12(11):e2202757
Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.
Li J, Sun Y, Zhao X, Ma Y, Xie Y, Liu S, Hui B, Shi X, Sun X, Zhang X
Cell death & disease 2023 Apr 8;14(4):259
Cell death & disease 2023 Apr 8;14(4):259
CCPG1 recognizes endoplasmic reticulum luminal proteins for selective ER-phagy.
Ishii S, Chino H, Ode KL, Kurikawa Y, Ueda HR, Matsuura A, Mizushima N, Itakura E
Molecular biology of the cell 2023 Apr 1;34(4):ar29
Molecular biology of the cell 2023 Apr 1;34(4):ar29
Evaluation of the synergistic effects of epigallocatechin-3-gallate-loaded PEGylated-PLGA nanoparticles with nimodipine against neuronal injury after subarachnoid hemorrhage.
Yang X, Han M, Wang X, Wang J, Sun X, Zhang C, Yan S, Huang L, Chen Y
Frontiers in nutrition 2022;9:953326
Frontiers in nutrition 2022;9:953326
Theabrownins Produced via Chemical Oxidation of Tea Polyphenols Inhibit Human Lung Cancer Cells in vivo and in vitro by Suppressing the PI3K/AKT/mTOR Pathway Activation and Promoting Autophagy.
Wang Y, Yuan Y, Wang C, Wang B, Zou W, Zhang N, Chen X
Frontiers in nutrition 2022;9:858261
Frontiers in nutrition 2022;9:858261
Cigarette Smoke Exposure Increases Glucose-6-phosphate Dehydrogenase, Autophagy, Fibrosis, and Senescence in Kidney Cells In Vitro and In Vivo.
Liu WC, Chuang HC, Chou CL, Lee YH, Chiu YJ, Wang YL, Chiu HW
Oxidative medicine and cellular longevity 2022;2022:5696686
Oxidative medicine and cellular longevity 2022;2022:5696686
LINC-PINT suppresses cisplatin resistance in gastric cancer by inhibiting autophagy activation via epigenetic silencing of ATG5 by EZH2.
Zhang C, Kang T, Wang X, Wang J, Liu L, Zhang J, Liu X, Li R, Wang J, Zhang J
Frontiers in pharmacology 2022;13:968223
Frontiers in pharmacology 2022;13:968223
Coxsackievirus B3 infection induces glycolysis to facilitate viral replication.
Qian Y, Yang Y, Qing W, Li C, Kong M, Kang Z, Zuo Y, Wu J, Yu M, Yang Z
Frontiers in microbiology 2022;13:962766
Frontiers in microbiology 2022;13:962766
Chrysophanol-8-O-glucoside protects mice against acute liver injury by inhibiting autophagy in hepatic stellate cells and inflammatory response in liver-resident macrophages.
Wang T, Lu Z, Qu XH, Xiong ZY, Wu YT, Luo Y, Zhang ZY, Han XJ, Xie CF
Frontiers in pharmacology 2022;13:951521
Frontiers in pharmacology 2022;13:951521
Toxoplasma gondii CDPK3 Controls the Intracellular Proliferation of Parasites in Macrophages.
Wu M, An R, Zhou N, Chen Y, Cai H, Yan Q, Wang R, Luo Q, Yu L, Chen L, Du J
Frontiers in immunology 2022;13:905142
Frontiers in immunology 2022;13:905142
Chlorin e6-Induced Photodynamic Effect Polarizes the Macrophage Into an M1 Phenotype Through Oxidative DNA Damage and Activation of STING.
Yu TT, Han N, Li LG, Peng XC, Li QR, Xu HZ, Wang XY, Yang ZY, Chen X, Wang MF, Li TF
Frontiers in pharmacology 2022;13:837784
Frontiers in pharmacology 2022;13:837784
ALG-bFGF Hydrogel Inhibiting Autophagy Contributes to Protection of Blood-Spinal Cord Barrier Integrity via PI3K/Akt/FOXO1/KLF4 Pathway After SCI.
Zhang R, Xie L, Wu F, Xu J, Lu L, Cao L, Li L, Meng W, Zhang H, Shao C, Li X, Chen D
Frontiers in pharmacology 2022;13:828896
Frontiers in pharmacology 2022;13:828896
Porcine cGAS-STING signaling induced autophagy inhibits STING downstream IFN and apoptosis.
Xia N, Zheng W, Jiang S, Cao Q, Luo J, Zhang J, Xu Y, Sun S, Zhang K, Chen N, Meurens F, Zhu J
Frontiers in immunology 2022;13:1021384
Frontiers in immunology 2022;13:1021384
Huaier suppresses pancreatic cancer progression via activating cell autophagy induced ferroptosis.
Zhu Z, Wang X, Zhang W, Gong M, Zhang S, Yang B, Qu B, Wu Z, Ma Q, Wang Z, Qian W
Frontiers in oncology 2022;12:960858
Frontiers in oncology 2022;12:960858
Polyvinylpyrrolidone-Modified Taxifolin Liposomes Promote Liver Repair by Modulating Autophagy to Inhibit Activation of the TLR4/NF-κB Signaling Pathway.
Ding Q, Liu W, Liu X, Ding C, Zhao Y, Dong L, Chen H, Sun S, Zhang Y, Zhang J, Wu M
Frontiers in bioengineering and biotechnology 2022;10:860515
Frontiers in bioengineering and biotechnology 2022;10:860515
Autophagy mediates the clearance of oligodendroglial SNCA/alpha-synuclein and TPPP/p25A in multiple system atrophy models.
Mavroeidi P, Arvanitaki F, Vetsi M, Becker S, Vlachakis D, Jensen PH, Stefanis L, Xilouri M
Autophagy 2022 Sep;18(9):2104-2133
Autophagy 2022 Sep;18(9):2104-2133
Selenomethionine alleviates NF-κB-mediated inflammation in bovine mammary epithelial cells induced by Escherichia coli by enhancing autophagy.
Tao L, Liu K, Li J, Zhang Y, Cui L, Dong J, Meng X, Zhu G, Wang H
International immunopharmacology 2022 Sep;110:108989
International immunopharmacology 2022 Sep;110:108989
Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.
Jin S, He X, Ma L, Zhuang Z, Wang Y, Lin M, Cai S, Wei L, Wang Z, Zhao Z, Wu Y, Sun L, Li C, Xie W, Zhao Y, Songyang Z, Peng K, Zhao J, Cui J
Nature communications 2022 Sep 3;13(1):5204
Nature communications 2022 Sep 3;13(1):5204
Activating PPARβ/δ Protects against Endoplasmic Reticulum Stress-Induced Astrocytic Apoptosis via UCP2-Dependent Mitophagy in Depressive Model.
Ji J, Li S, Jiang Z, Yu J, Sun Y, Cai Z, Dong Y, Sun X
International journal of molecular sciences 2022 Sep 16;23(18)
International journal of molecular sciences 2022 Sep 16;23(18)
Malvidin protects against lipopolysaccharide-induced acute liver injury in mice via regulating Nrf2 and NLRP3 pathways and suppressing apoptosis and autophagy.
Fan H, Cui J, Liu F, Zhang W, Yang H, He N, Dong Z, Dong J
European journal of pharmacology 2022 Oct 15;933:175252
European journal of pharmacology 2022 Oct 15;933:175252
New insights into the interaction between duodenal toxicity and microbiota disorder under copper exposure in chicken: Involving in endoplasmic reticulum stress and mitochondrial toxicity.
Ma F, Huo Y, Li H, Yang F, Liao J, Han Q, Li Y, Pan J, Hu L, Guo J, Tang Z
Chemico-biological interactions 2022 Oct 1;366:110132
Chemico-biological interactions 2022 Oct 1;366:110132
Difenoconazole disrupts the blood-brain barrier and results in neurotoxicity in carp by inhibiting the Nrf2 pathway mediated ROS accumulation.
Liu F, Wang Y, Chen L, Bello BK, Zhang T, Yang H, Li X, Pan E, Feng H, Dong J
Ecotoxicology and environmental safety 2022 Oct 1;244:114081
Ecotoxicology and environmental safety 2022 Oct 1;244:114081
N-linoleyltyrosine protects neurons against Aβ(1-40)-induced cell toxicity via autophagy involving the CB(2)/AMPK/mTOR/ULK1 pathway.
Zhou Y, Li ZX, Liu YT, Xu ZC, Hu Y, Lv W, Yang ZY, Sheng YM, Liu S
Brain research bulletin 2022 Oct 1;188:203-213
Brain research bulletin 2022 Oct 1;188:203-213
Berbamine hydrochloride inhibits bovine viral diarrhea virus replication via interfering in late-stage autophagy.
Wang J, Yang G, Zhang L, Zhang J, Wang J, Zou Y, Wang J
Virus research 2022 Nov;321:198905
Virus research 2022 Nov;321:198905
Bifendate inhibits autophagy at multiple steps and attenuates oleic acid-induced lipid accumulation.
Yuan W, Jian F, Rong Y
Biochemical and biophysical research communications 2022 Nov 26;631:115-123
Biochemical and biophysical research communications 2022 Nov 26;631:115-123
O-GlcNAcylation of SIRT1 Protects against Cold Stress-Induced Skeletal Muscle Damage via Amelioration of Mitochondrial Homeostasis.
Cao Y, Zhang M, Li Y, Lu J, Zhou W, Li X, Shi H, Xu B, Li S
International journal of molecular sciences 2022 Nov 22;23(23)
International journal of molecular sciences 2022 Nov 22;23(23)
Gaseous signal molecule SO(2) regulates autophagy through PI3K/AKT pathway inhibits cardiomyocyte apoptosis and improves myocardial fibrosis in rats with type II diabetes.
Zhao J, Wu Q, Yang T, Nie L, Liu S, Zhou J, Chen J, Jiang Z, Xiao T, Yang J, Chu C
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2022 Nov 1;26(6):541-556
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2022 Nov 1;26(6):541-556
Repeated social defeat stress inhibits development of hippocampus neurons through mitophagy and autophagy.
Guo L, Jiang ZM, Sun RX, Pang W, Zhou X, Du ML, Chen MX, Lv X, Wang JT
Brain research bulletin 2022 May;182:111-117
Brain research bulletin 2022 May;182:111-117
Elevated ATG13 in serum of patients with ME/CFS stimulates oxidative stress response in microglial cells via activation of receptor for advanced glycation end products (RAGE).
Gottschalk G, Peterson D, Knox K, Maynard M, Whelan RJ, Roy A
Molecular and cellular neurosciences 2022 May;120:103731
Molecular and cellular neurosciences 2022 May;120:103731
CCDC50 suppresses NLRP3 inflammasome activity by mediating autophagic degradation of NLRP3.
Lin Y, Li Z, Wang Y, Tian T, Jia P, Ye Y, He M, Yang Z, Li C, Guo D, Hou P
EMBO reports 2022 May 4;23(5):e54453
EMBO reports 2022 May 4;23(5):e54453
Quercus acutissima Carruth. root extract triggers apoptosis, autophagy and inhibits cell viability in breast cancer cells.
Ding W, Chen C, Li J, Geng X, Zhang H, Sun Y
Journal of ethnopharmacology 2022 May 10;289:115039
Journal of ethnopharmacology 2022 May 10;289:115039
Sec23a inhibits the self-renewal of melanoma cancer stem cells via inactivation of ER-phagy.
Sun Z, Liu D, Zeng B, Zhao Q, Li X, Chen H, Wang J, Rosie Xing H
Cell communication and signaling : CCS 2022 Mar 2;20(1):22
Cell communication and signaling : CCS 2022 Mar 2;20(1):22
Dietary folic acid supplementation improves semen quality and spermatogenesis through altering autophagy and histone methylation in the testis of aged broiler breeder roosters.
Ye N, Lv Z, Huang Z, Cheng Y, Wei Q, Shi F
Theriogenology 2022 Mar 15;181:8-15
Theriogenology 2022 Mar 15;181:8-15
Extracellular vesicles originating from autophagy mediate an antibody-resistant spread of classical swine fever virus in cell culture.
Wang T, Zhang L, Liang W, Liu S, Deng W, Liu Y, Liu Y, Song M, Guo K, Zhang Y
Autophagy 2022 Jun;18(6):1433-1449
Autophagy 2022 Jun;18(6):1433-1449
Decreased Krüppel-like factor 4 in adenomyosis impairs decidualization by repressing autophagy in human endometrial stromal cells.
Mei J, Sheng X, Yan Y, Cai X, Zhang C, Tian J, Zhang M, Zhou J, Shan H, Huang C
BMC molecular and cell biology 2022 Jun 27;23(1):24
BMC molecular and cell biology 2022 Jun 27;23(1):24
Macrophages disseminate pathogen associated molecular patterns through the direct extracellular release of the soluble content of their phagolysosomes.
Greene CJ, Nguyen JA, Cheung SM, Arnold CR, Balce DR, Wang YT, Soderholm A, McKenna N, Aggarwal D, Campden RI, Ewanchuk BW, Virgin HW, Yates RM
Nature communications 2022 Jun 2;13(1):3072
Nature communications 2022 Jun 2;13(1):3072
Integrated metabolism and epigenetic modifications in the macrophages of mice in responses to cold stress.
Lu J, Fu S, Dai J, Hu J, Li S, Ji H, Wang Z, Yu J, Bao J, Xu B, Guo J, Yang H
Journal of Zhejiang University. Science. B 2022 Jun 15;23(6):461-480
Journal of Zhejiang University. Science. B 2022 Jun 15;23(6):461-480
Autophagy deficiency promotes lung metastasis of prostate cancer via stabilization of TWIST1.
Shi YX, Sun ZW, Jia DL, Wang HB
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2022 Jul;24(7):1403-1412
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2022 Jul;24(7):1403-1412
Extracellular vesicle miR-32 derived from macrophage promotes arterial calcification in mice with type 2 diabetes via inhibiting VSMC autophagy.
Cao J, Chen C, Chen Q, Gao Y, Zhao Z, Yuan Q, Li A, Yang S, He Y, Zu X, Liu J
Journal of translational medicine 2022 Jul 6;20(1):307
Journal of translational medicine 2022 Jul 6;20(1):307
The Protective Effect of Lycium Ruthenicum Murr Anthocyanins in Cr (VI)-Induced Mitophagy in DF-1 Cells.
Guo S, Qi M, Li H, Cui Y, Qi C, Cheng G, Lv M, Zheng P, Liu J
Life (Basel, Switzerland) 2022 Jul 25;12(8)
Life (Basel, Switzerland) 2022 Jul 25;12(8)
Ciliary Type III Adenylyl Cyclase in the VMH Is Crucial for High-Fat Diet-Induced Obesity Mediated by Autophagy.
Yang D, Wu X, Wang W, Zhou Y, Wang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jan;9(3):e2102568
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jan;9(3):e2102568
Calycosin ameliorates atherosclerosis by enhancing autophagy via regulating the interaction between KLF2 and MLKL in apolipoprotein E gene-deleted mice.
Ma C, Wu H, Yang G, Xiang J, Feng K, Zhang J, Hua Y, Kang L, Fan G, Yang S
British journal of pharmacology 2022 Jan;179(2):252-269
British journal of pharmacology 2022 Jan;179(2):252-269
Disruption of actin dynamics induces autophagy of the eukaryotic chaperonin TRiC/CCT.
Date Y, Matsuura A, Itakura E
Cell death discovery 2022 Jan 25;8(1):37
Cell death discovery 2022 Jan 25;8(1):37
The effect of QiangGuYin on osteoporosis through the AKT/mTOR/autophagy signaling pathway mediated by CKIP-1.
Yuan Y, Sun J, Zhou H, Wang S, He C, Chen T, Fang M, Li S, Kang S, Huang X, Tang B, Liang B, Mao Y, Li J, Shi X, Liu K
Aging 2022 Jan 24;14(2):892-906
Aging 2022 Jan 24;14(2):892-906
PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells by phosphorylating PRAS40.
Zhang T, Wang Y, Yu H, Zhang T, Guo L, Xu J, Wei X, Wang N, Wu Y, Wang X, Huang L
Cell death & disease 2022 Jan 20;13(1):68
Cell death & disease 2022 Jan 20;13(1):68
Muyin extract inhibits non-small-cell lung cancer growth by inducing autophagy and apoptosis in vitro and in vivo.
Kan Y, Song M, Cui X, Yang Q, Zang Y, Li Q, Li Y, Cai W, Chen Y, Weng X, Wang Y, Zhu X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153834
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153834
The dynamic changes in autophagy activity and its role in lung injury after deep hypothermic circulatory arrest.
Kong M, Wei D, Li X, Zhu X, Hong Z, Ni M, Wang Y, Dong A
Journal of cellular and molecular medicine 2022 Feb;26(4):1113-1127
Journal of cellular and molecular medicine 2022 Feb;26(4):1113-1127
S-20, a steroidal saponin from the berries of black nightshade, exerts anti-multidrug resistance activity in K562/ADR cells through autophagic cell death and ERK activation.
Wang Y, Xu J, Wang Y, Xiang L, He X
Food & function 2022 Feb 21;13(4):2200-2215
Food & function 2022 Feb 21;13(4):2200-2215
ATP6V1H deficiency impairs glucose tolerance by augmenting endoplasmic reticulum stress in high fat diet fed mice.
Yang S, Hou Y, Zhang H, Hao Y, Zhang Y, Zhao Z, Ruan W, Duan X
Archives of biochemistry and biophysics 2022 Feb 15;716:109116
Archives of biochemistry and biophysics 2022 Feb 15;716:109116
Ultrasound-triggered microbubble destruction enhances the radiosensitivity of glioblastoma by inhibiting PGRMC1-mediated autophagy in vitro and in vivo.
He Y, Dong XH, Zhu Q, Xu YL, Chen ML, Liu Z
Military Medical Research 2022 Feb 14;9(1):9
Military Medical Research 2022 Feb 14;9(1):9
Inhibition of HSPA8 by rifampicin contributes to ferroptosis via enhancing autophagy.
Zhou J, Tan Y, Hu L, Fu J, Li D, Chen J, Long Y
Liver international : official journal of the International Association for the Study of the Liver 2022 Dec;42(12):2889-2899
Liver international : official journal of the International Association for the Study of the Liver 2022 Dec;42(12):2889-2899
ATG5-Mediated Autophagy May Inhibit Pyroptosis to Ameliorate Oleic Acid-Induced Hepatocyte Steatosis.
Tang Q, Liu W, Yang X, Tian Y, Chen J, Hu Y, Fu N
DNA and cell biology 2022 Dec;41(12):1038-1052
DNA and cell biology 2022 Dec;41(12):1038-1052
Loss of ATG5 in KRT14(+) cells leads to accumulated functional impairments of salivary glands via pyroptosis.
Yu S, Wang H, Liu M, Pei F, Liu H, Zhang J, Zhang L, Li Q, Chen Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Dec;36(12):e22631
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Dec;36(12):e22631
Highly expressed SERCA2 triggers tumor cell autophagy and is a druggable vulnerability in triple-negative breast cancer.
Fan M, Gao J, Zhou L, Xue W, Wang Y, Chen J, Li W, Yu Y, Liu B, Shen Y, Xu Q
Acta pharmaceutica Sinica. B 2022 Dec;12(12):4407-4423
Acta pharmaceutica Sinica. B 2022 Dec;12(12):4407-4423
Targeting CRL4 suppresses chemoresistant ovarian cancer growth by inducing mitophagy.
Meng Y, Qiu L, Zeng X, Hu X, Zhang Y, Wan X, Mao X, Wu J, Xu Y, Xiong Q, Chen Z, Zhang B, Han J
Signal transduction and targeted therapy 2022 Dec 9;7(1):388
Signal transduction and targeted therapy 2022 Dec 9;7(1):388
Sulforaphane Ameliorates Hepatic Lipid Metabolism via Modulating Lipophagy In Vivo and In Vitro.
Lei P, Hu Y, Gao P, Ding Q, Yan J, Zhao J, Li B, Shan Y
Journal of agricultural and food chemistry 2022 Dec 7;70(48):15126-15133
Journal of agricultural and food chemistry 2022 Dec 7;70(48):15126-15133
Endosomal lipid signaling reshapes the endoplasmic reticulum to control mitochondrial function.
Jang W, Puchkov D, Samsó P, Liang Y, Nadler-Holly M, Sigrist SJ, Kintscher U, Liu F, Mamchaoui K, Mouly V, Haucke V
Science (New York, N.Y.) 2022 Dec 16;378(6625):eabq5209
Science (New York, N.Y.) 2022 Dec 16;378(6625):eabq5209
LncRNA CCAT1 Upregulates ATG5 to Enhance Autophagy and Promote Gastric Cancer Development by Absorbing miR-140-3p.
Yang F, Peng ZX, Ji WD, Yu JD, Qian C, Liu JD, Fang GE
Digestive diseases and sciences 2022 Aug;67(8):3725-3741
Digestive diseases and sciences 2022 Aug;67(8):3725-3741
Oridonin relieves depressive-like behaviors by inhibiting neuroinflammation and autophagy impairment in rats subjected to chronic unpredictable mild stress.
Liang L, Wang H, Hu Y, Bian H, Xiao L, Wang G
Phytotherapy research : PTR 2022 Aug;36(8):3335-3351
Phytotherapy research : PTR 2022 Aug;36(8):3335-3351
CD13 downregulation mediated by ubenimex inhibits autophagy to overcome 5-FU resistance by disturbing the EMP3/FAK/NF-κB pathway in gastric cancer cells.
Xiu T, Guo Q, Jing F, Shi Y, Jing F
Translational cancer research 2022 Aug;11(8):2487-2500
Translational cancer research 2022 Aug;11(8):2487-2500
Mucin O-glycan-microbiota axis orchestrates gut homeostasis in a diarrheal pig model.
Xia B, Zhong R, Wu W, Luo C, Meng Q, Gao Q, Zhao Y, Chen L, Zhang S, Zhao X, Zhang H
Microbiome 2022 Aug 31;10(1):139
Microbiome 2022 Aug 31;10(1):139
The microRNA-10b-Bim axis promotes cancer progression through activating autophagy in oral squamous cell carcinoma.
Li S, Gao L, Liu J, Guo C, Zheng J, Zhi K, Ren W
Cell death discovery 2022 Aug 25;8(1):373
Cell death discovery 2022 Aug 25;8(1):373
Acetyl CoA synthase 2 potentiates ATG5-induced autophagy against neuronal apoptosis after subarachnoid hemorrhage.
He W, Zhou X, Wu Q, Zhou L, Zhang Z, Zhang R, Deng C, Zhang X
Journal of molecular histology 2022 Apr;53(2):511-521
Journal of molecular histology 2022 Apr;53(2):511-521
Asymmetric Pericentrosomal CD133 Endosomes Induce the Unequal Autophagic Activity During Cytokinesis in CD133-Positive Human Neuroblastoma Cells.
Izumi H, Li Y, Yasunami M, Sato S, Mae T, Kaneko Y, Nakagawara A
Stem cells (Dayton, Ohio) 2022 Apr 29;40(4):371-384
Stem cells (Dayton, Ohio) 2022 Apr 29;40(4):371-384
Let-7i-5p promotes a malignant phenotype in nasopharyngeal carcinoma via inhibiting tumor-suppressive autophagy.
You B, Zhang P, Gu M, Yin H, Fan Y, Yao H, Pan S, Xie H, Cheng T, Liu H, You Y, Liu J
Cancer letters 2022 Apr 10;531:14-26
Cancer letters 2022 Apr 10;531:14-26
LncRNA FEZF1-AS1 Promotes Multi-Drug Resistance of Gastric Cancer Cells via Upregulating ATG5.
Gui Z, Zhao Z, Sun Q, Shao G, Huang J, Zhao W, Kuang Y
Frontiers in cell and developmental biology 2021;9:749129
Frontiers in cell and developmental biology 2021;9:749129
Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS.
Shang Y, Wang Q, Li J, Liu H, Zhao Q, Huang X, Dong H, Chen W, Gui R, Nie X
Frontiers in chemistry 2021;9:522708
Frontiers in chemistry 2021;9:522708
Autophagic Flux Unleashes GATA4-NF-κB Axis to Promote Antioxidant Defense-Dependent Survival of Colorectal Cancer Cells under Chronic Acidosis.
Liu X, Zhao M, Sun X, Meng Z, Bai X, Gong Y, Xu L, Hao X, Yang T, Wei Z, Zhang X, Guo H, Li P, Liu Q, Gong Y, Shi Y, Shao C
Oxidative medicine and cellular longevity 2021;2021:8189485
Oxidative medicine and cellular longevity 2021;2021:8189485
Silica Nanoparticles Promote α-Synuclein Aggregation and Parkinson's Disease Pathology.
Yuan X, Yang Y, Xia D, Meng L, He M, Liu C, Zhang Z
Frontiers in neuroscience 2021;15:807988
Frontiers in neuroscience 2021;15:807988
FBXO22 Promotes Growth and Metastasis and Inhibits Autophagy in Epithelial Ovarian Cancers via the MAPK/ERK Pathway.
Li M, Zhao X, Yong H, Shang B, Lou W, Wang Y, Bai J
Frontiers in pharmacology 2021;12:778698
Frontiers in pharmacology 2021;12:778698
Characterization of Interplay Between Autophagy and Ferroptosis and Their Synergistical Roles on Manipulating Immunological Tumor Microenvironment in Squamous Cell Carcinomas.
Chen L, Niu X, Qiao X, Liu S, Ma H, Shi X, He X, Zhong M
Frontiers in immunology 2021;12:739039
Frontiers in immunology 2021;12:739039
Lactobacillus rhamnosus GR-1 Prevents Escherichia coli-Induced Apoptosis Through PINK1/Parkin-Mediated Mitophagy in Bovine Mastitis.
Li Y, Zhu Y, Chu B, Liu N, Chen S, Wang J
Frontiers in immunology 2021;12:715098
Frontiers in immunology 2021;12:715098
Taurine Alleviates Streptococcus uberis-Induced Inflammation by Activating Autophagy in Mammary Epithelial Cells.
Wang Z, Lan R, Xu Y, Zuo J, Han X, Phouthapane V, Luo Z, Miao J
Frontiers in immunology 2021;12:631113
Frontiers in immunology 2021;12:631113
SNHG9, a Papillary Thyroid Cancer Cell Exosome-Enriched lncRNA, Inhibits Cell Autophagy and Promotes Cell Apoptosis of Normal Thyroid Epithelial Cell Nthy-ori-3 Through YBOX3/P21 Pathway.
Wen D, Liu WL, Lu ZW, Cao YM, Ji QH, Wei WJ
Frontiers in oncology 2021;11:647034
Frontiers in oncology 2021;11:647034
Degradation of lipid droplets by chimeric autophagy-tethering compounds.
Fu Y, Chen N, Wang Z, Luo S, Ding Y, Lu B
Cell research 2021 Sep;31(9):965-979
Cell research 2021 Sep;31(9):965-979
Latcripin-7A from Lentinula edodes C91-3 induces apoptosis, autophagy, and cell cycle arrest at G1 phase in human gastric cancer cells via inhibiting PI3K/Akt/mTOR signaling.
Din SRU, Nisar MA, Ramzan MN, Saleem MZ, Ghayas H, Ahmad B, Batool S, Kifayat K, Guo X, Huang M, Zhong M
European journal of pharmacology 2021 Sep 15;907:174305
European journal of pharmacology 2021 Sep 15;907:174305
UPF1 impacts on mTOR signaling pathway and autophagy in endometrioid endometrial carcinoma.
Zhang M, Chen H, Qin P, Cai T, Li L, Chen R, Liu S, Chen H, Lin W, Chen H, Strickland AL, Xiong H, Jiang Q
Aging 2021 Sep 14;13(17):21202-21215
Aging 2021 Sep 14;13(17):21202-21215
LncRNA OIP5-AS1 inhibits ferroptosis in prostate cancer with long-term cadmium exposure through miR-128-3p/SLC7A11 signaling.
Zhang Y, Guo S, Wang S, Li X, Hou D, Li H, Wang L, Xu Y, Ma B, Wang H, Jiang X
Ecotoxicology and environmental safety 2021 Sep 1;220:112376
Ecotoxicology and environmental safety 2021 Sep 1;220:112376
The anticancer activity of root extract from Quercus acutissima Carruth. Via regulating apoptosis and autophagy in breast cancer cells.
Chen C, Ding W, Li J, Geng X, Zhang H, Sun Y
Journal of ethnopharmacology 2021 Oct 8;:114730
Journal of ethnopharmacology 2021 Oct 8;:114730
Hepatoprotective effects of ginsenoside Rk3 in acetaminophen-induced liver injury in mice by activation of autophagy.
Qu L, Fu R, Ma X, Fan D
Food & function 2021 Oct 4;12(19):9128-9140
Food & function 2021 Oct 4;12(19):9128-9140
Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy.
Han Y, Xiong S, Zhao H, Yang S, Yang M, Zhu X, Jiang N, Xiong X, Gao P, Wei L, Xiao Y, Sun L
Cell death & disease 2021 Oct 30;12(11):1031
Cell death & disease 2021 Oct 30;12(11):1031
Metformin sensitises hepatocarcinoma cells to methotrexate by targeting dihydrofolate reductase.
Wang Y, Lu H, Sun L, Chen X, Wei H, Suo C, Feng J, Yuan M, Shen S, Jia W, Wang Y, Zhang H, Li Z, Zhong X, Gao P
Cell death & disease 2021 Oct 2;12(10):902
Cell death & disease 2021 Oct 2;12(10):902
Macroautophagy supports Sonic Hedgehog signaling by promoting Patched1 degradation.
Yang X, Jin N, Wang Y, Yao Y, Wang Y, Li T, Liu C, Yu T, Yin H, Zhang Z, Cheng SY, Yue S
Biochimica et biophysica acta. Molecular cell research 2021 Nov;1868(12):119124
Biochimica et biophysica acta. Molecular cell research 2021 Nov;1868(12):119124
Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4.
Huang T, Xu T, Wang Y, Zhou Y, Yu D, Wang Z, He L, Chen Z, Zhang Y, Davidson D, Dai Y, Hang C, Liu X, Yan C
Autophagy 2021 Nov;17(11):3592-3606
Autophagy 2021 Nov;17(11):3592-3606
OAB-14 Effectively Ameliorates the Dysfunction of the Endosomal-Autophagic-Lysosomal Pathway in APP/PS1 Transgenic Mice.
Guo X, Bao X, Wang X, Liu D, Liu P, Chi T, Ji X, Zheng Z, Chen G, Zou L
ACS chemical neuroscience 2021 Nov 3;12(21):3985-3993
ACS chemical neuroscience 2021 Nov 3;12(21):3985-3993
Exopolysaccharides from Bifidobacterium animalis Ameliorate Escherichia coli-Induced IPEC-J2 Cell Damage via Inhibiting Apoptosis and Restoring Autophagy.
Yuan L, Chu B, Chen S, Li Y, Liu N, Zhu Y, Zhou D
Microorganisms 2021 Nov 16;9(11)
Microorganisms 2021 Nov 16;9(11)
Aristolochic acid I induces impairment in spermatogonial stem cell in rodents.
Liu Y, He X, Wang Y, Zhou H, Zhang Y, Ma J, Wang Z, Yang F, Lu H, Yang Y, Deng Z, Qi X, Gong L, Ren J
Toxicology research 2021 May;10(3):436-445
Toxicology research 2021 May;10(3):436-445
H(+)/Cl(‑) exchange transporter 7 promotes lysosomal acidification‑mediated autophagy in mouse cardiomyocytes.
Lin J, Wei J, Lv Y, Zhang X, Yi RF, Dai C, Zhang Q, Jia J, Zhang D, Huang Y
Molecular medicine reports 2021 Mar;23(3)
Molecular medicine reports 2021 Mar;23(3)
Hypoxia-induced acetylation of PAK1 enhances autophagy and promotes brain tumorigenesis via phosphorylating ATG5.
Feng X, Zhang H, Meng L, Song H, Zhou Q, Qu C, Zhao P, Li Q, Zou C, Liu X, Zhang Z
Autophagy 2021 Mar;17(3):723-742
Autophagy 2021 Mar;17(3):723-742
Autophagy-induced p62 accumulation is required for curcumol to regulate KLF5-mediated angiogenesis in liver sinusoidal endothelial cells.
Gao L, Yang X, Liang B, Jia Y, Tan S, Chen A, Cao P, Zhang Z, Zheng S, Sun L, Zhang F, Shao J
Toxicology 2021 Mar 30;452:152707
Toxicology 2021 Mar 30;452:152707
Nuclear translocation of ATG5 induces DNA mismatch repair deficiency (MMR-D)/microsatellite instability (MSI) via interacting with Mis18α in colorectal cancer.
Sun SY, Hu XT, Yu XF, Zhang YY, Liu XH, Liu YH, Wu SH, Li YY, Cui SX, Qu XJ
British journal of pharmacology 2021 Jun;178(11):2351-2369
British journal of pharmacology 2021 Jun;178(11):2351-2369
Endoplasmic reticulum stress manipulates autophagic response that antagonizes polybrominated diphenyl ethers quinone induced cytotoxicity in microglial BV2 cells.
Zhu Q, Liu Z, Wang Y, Song E, Song Y
Journal of hazardous materials 2021 Jun 5;411:124958
Journal of hazardous materials 2021 Jun 5;411:124958
DUSP1 overexpression attenuates renal tubular mitochondrial dysfunction by restoring Parkin-mediated mitophagy in diabetic nephropathy.
Lu C, Wu B, Liao Z, Xue M, Zou Z, Feng J, Sheng J
Biochemical and biophysical research communications 2021 Jun 25;559:141-147
Biochemical and biophysical research communications 2021 Jun 25;559:141-147
Citrate activates autophagic death of prostate cancer cells via downregulation CaMKII/AKT/mTOR pathway.
Fan X, Zhou J, Yan X, Bi X, Liang J, Lu S, Luo L, Zhou D, Yin Z
Life sciences 2021 Jun 15;275:119355
Life sciences 2021 Jun 15;275:119355
Metformin attenuates atherosclerosis and plaque vulnerability by upregulating KLF2-mediated autophagy in apoE(-/-) mice.
Wu H, Feng K, Zhang C, Zhang H, Zhang J, Hua Y, Dong Z, Zhu Y, Yang S, Ma C
Biochemical and biophysical research communications 2021 Jun 11;557:334-341
Biochemical and biophysical research communications 2021 Jun 11;557:334-341
Autophagy regulates functional differentiation of mammary epithelial cells.
Elswood J, Pearson SJ, Payne HR, Barhoumi R, Rijnkels M, W Porter W
Autophagy 2021 Feb;17(2):420-438
Autophagy 2021 Feb;17(2):420-438
CircCDK8 regulates osteogenic differentiation and apoptosis of PDLSCs by inducing ER stress/autophagy during hypoxia.
Zheng J, Zhu X, He Y, Hou S, Liu T, Zhi K, Hou T, Gao L
Annals of the New York Academy of Sciences 2021 Feb;1485(1):56-70
Annals of the New York Academy of Sciences 2021 Feb;1485(1):56-70
Autophagy Blockade Limits HER2+ Breast Cancer Tumorigenesis by Perturbing HER2 Trafficking and Promoting Release Via Small Extracellular Vesicles.
Hao M, Yeo SK, Turner K, Harold A, Yang Y, Zhang X, Guan JL
Developmental cell 2021 Feb 8;56(3):341-355.e5
Developmental cell 2021 Feb 8;56(3):341-355.e5
Saponins from Panax japonicus attenuate cognitive impairment in ageing rats through regulating microglial polarisation and autophagy.
Pi XJ, Zhao QQ, Wang JX, Zhang XL, Yuan D, Hu SS, He YM, Zhang CC, Zhou ZY, Wang T
Pharmaceutical biology 2021 Dec;59(1):1117-1125
Pharmaceutical biology 2021 Dec;59(1):1117-1125
Loss of SMARCB1 promotes autophagy and facilitates tumour progression in chordoma by transcriptionally activating ATG5.
Li M, Shen Y, Xiong Y, Wang S, Li C, Bai J, Zhang Y
Cell proliferation 2021 Dec;54(12):e13136
Cell proliferation 2021 Dec;54(12):e13136
Long‑chain non‑coding RNA GAS5 promotes cell autophagy by modulating the miR‑181c‑5p/ATG5 and miR‑1192/ATG12 axes.
Xu T, Xu X, Chu Y, Jiang D, Xu G
International journal of molecular medicine 2021 Dec;48(6)
International journal of molecular medicine 2021 Dec;48(6)
6-Shogaol from ginger shows anti-tumor effect in cervical carcinoma via PI3K/Akt/mTOR pathway.
Pei XD, He ZL, Yao HL, Xiao JS, Li L, Gu JZ, Shi PZ, Wang JH, Jiang LH
European journal of nutrition 2021 Aug;60(5):2781-2793
European journal of nutrition 2021 Aug;60(5):2781-2793
Ozone induces tolerance against cardiomyocytes oxygen-glucose deprivation/reperfusion through inhibition of autophagy pathway.
Xu L, Zhu L, Liu P, Wu Z, Zou Z
Experimental and therapeutic medicine 2021 Aug;22(2):869
Experimental and therapeutic medicine 2021 Aug;22(2):869
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
Xie C, Zhou X, Liang C, Li X, Ge M, Chen Y, Yin J, Zhu J, Zhong C
Journal of experimental & clinical cancer research : CR 2021 Aug 24;40(1):266
Journal of experimental & clinical cancer research : CR 2021 Aug 24;40(1):266
Mild hypothermia pretreatment extenuates liver ischemia-reperfusion injury through Rab7-mediated autophagosomes-lysosomes fusion.
Liu A, Wang W, Lu Z, Liu Z, Zhou W, Zhong Z, Ye Q
Biochemical and biophysical research communications 2021 Apr 23;550:15-21
Biochemical and biophysical research communications 2021 Apr 23;550:15-21
Coibamide A kills cancer cells through inhibiting autophagy.
Shi W, Lu D, Wu C, Li M, Ding Z, Li Y, Chen B, Lin X, Su W, Shao X, Xia Z, Fang L, Liu K, Li H
Biochemical and biophysical research communications 2021 Apr 2;547:52-58
Biochemical and biophysical research communications 2021 Apr 2;547:52-58
HDAC6 Regulates the Fusion of Autophagosome and Lysosome to Involve in Odontoblast Differentiation.
Zhan Y, Wang H, Zhang L, Pei F, Chen Z
Frontiers in cell and developmental biology 2020;8:605609
Frontiers in cell and developmental biology 2020;8:605609
Autophagy Contributes to the Maintenance of Genomic Integrity by Reducing Oxidative Stress.
Bu W, Hao X, Yang T, Wang J, Liu Q, Zhang X, Li X, Gong Y, Shao C
Oxidative medicine and cellular longevity 2020;2020:2015920
Oxidative medicine and cellular longevity 2020;2020:2015920
The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis.
Shang Y, Wang Q, Li J, Zhao Q, Huang X, Dong H, Liu H, Zhang Y, Zhang J, Gui R, Nie X
OncoTargets and therapy 2020;13:473-486
OncoTargets and therapy 2020;13:473-486
The Effects of Puerarin on Autophagy Through Regulating of the PERK/eIF2α/ATF4 Signaling Pathway Influences Renal Function in Diabetic Nephropathy.
Xu X, Chen B, Huang Q, Wu Y, Liang T
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:2583-2592
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:2583-2592
Empagliflozin Alleviates Hepatic Steatosis by Activating the AMPK-TET2-Autophagy Pathway in vivo and in vitro.
Li T, Fang T, Xu L, Liu X, Li X, Xue M, Yu X, Sun B, Chen L
Frontiers in pharmacology 2020;11:622153
Frontiers in pharmacology 2020;11:622153
Cardamonin Reduces Acetaminophen-Induced Acute Liver Injury in Mice via Activating Autophagy and NFE2L2 Signaling.
Xu Q, Fan Y, Loor JJ, Liang Y, Sun X, Jia H, Zhao C, Xu C
Frontiers in pharmacology 2020;11:601716
Frontiers in pharmacology 2020;11:601716
CDKL3 Targets ATG5 to Promote Carcinogenesis of Esophageal Squamous Cell Carcinoma.
Zhou S, Zhang M, Zhou C, Wang W, Yang H, Ye W
Frontiers in oncology 2020;10:1602
Frontiers in oncology 2020;10:1602
FTO accelerates ovarian cancer cell growth by promoting proliferation, inhibiting apoptosis, and activating autophagy.
Zhao L, Kong X, Zhong W, Wang Y, Li P
Pathology, research and practice 2020 Sep;216(9):153042
Pathology, research and practice 2020 Sep;216(9):153042
NOD2/c-Jun NH(2)-Terminal Kinase Triggers Mycoplasma ovipneumoniae-Induced Macrophage Autophagy.
Luo H, Wu X, Xu Z, Hao X, Wang Y, Li M
Journal of bacteriology 2020 Sep 23;202(20)
Journal of bacteriology 2020 Sep 23;202(20)
Autophagy plays a protective role during Pseudomonas aeruginosa-induced apoptosis via ROS-MAPK pathway.
Han L, Ma Q, Yu J, Gong Z, Ma C, Xu Y, Deng G, Wu X
Innate immunity 2020 Oct;26(7):580-591
Innate immunity 2020 Oct;26(7):580-591
Effect of autophagy on irradiation‑induced damage in osteoblast‑like MC3T3‑E1 cells.
Li R, Yang W, Hu X, Zhou D, Huang K, Wang C, Li Y, Liu B
Molecular medicine reports 2020 Oct;22(4):3473-3481
Molecular medicine reports 2020 Oct;22(4):3473-3481
Apatinib induces apoptosis and autophagy via the PI3K/AKT/mTOR and MAPK/ERK signaling pathways in neuroblastoma.
Yu X, Fan H, Jiang X, Zheng W, Yang Y, Jin M, Ma X, Jiang W
Oncology letters 2020 Oct;20(4):52
Oncology letters 2020 Oct;20(4):52
HIF-1α-Mediated Mitophagy Determines ZnO Nanoparticle-Induced Human Osteosarcoma Cell Death both In Vitro and In Vivo.
He G, Pan X, Liu X, Zhu Y, Ma Y, Du C, Liu X, Mao C
ACS applied materials & interfaces 2020 Oct 28;12(43):48296-48309
ACS applied materials & interfaces 2020 Oct 28;12(43):48296-48309
N‑linoleyltyrosine protects PC12 cells against oxidative damage via autophagy: Possible involvement of CB1 receptor regulation.
Liu X, Wu Y, Zhou D, Xie Y, Zhou Y, Lu Y, Yang R, Liu S
International journal of molecular medicine 2020 Nov;46(5):1827-1837
International journal of molecular medicine 2020 Nov;46(5):1827-1837
PINK1-mediated mitophagy protects against hepatic ischemia/reperfusion injury by restraining NLRP3 inflammasome activation.
Xu Y, Tang Y, Lu J, Zhang W, Zhu Y, Zhang S, Ma G, Jiang P, Zhang W
Free radical biology & medicine 2020 Nov 20;160:871-886
Free radical biology & medicine 2020 Nov 20;160:871-886
Cannabinoid receptor 2 activation alleviates septic lung injury by promoting autophagy via inhibition of inflammatory mediator release.
Liu AP, Yuan QH, Zhang B, Yang L, He QW, Chen K, Liu QS, Li Z, Zhan J
Cellular signalling 2020 May;69:109556
Cellular signalling 2020 May;69:109556
ADAM12 silencing promotes cellular apoptosis by activating autophagy in choriocarcinoma cells.
Wang L, Tan Z, Zhang Y, Kady Keita N, Liu H, Zhang Y
International journal of oncology 2020 May;56(5):1162-1174
International journal of oncology 2020 May;56(5):1162-1174
Yeast β-D-glucan exerts antitumour activity in liver cancer through impairing autophagy and lysosomal function, promoting reactive oxygen species production and apoptosis.
Wang N, Liu H, Liu G, Li M, He X, Yin C, Tu Q, Shen X, Bai W, Wang Q, Tao Y, Yin H
Redox biology 2020 May;32:101495
Redox biology 2020 May;32:101495
Upregulated NTF4 in colorectal cancer promotes tumor development via regulating autophagy.
Yang Z, Chen Y, Wei X, Wu D, Min Z, Quan Y
International journal of oncology 2020 Jun;56(6):1442-1454
International journal of oncology 2020 Jun;56(6):1442-1454
The RBP1-CKAP4 axis activates oncogenic autophagy and promotes cancer progression in oral squamous cell carcinoma.
Gao L, Wang Q, Ren W, Zheng J, Li S, Dou Z, Kong X, Liang X, Zhi K
Cell death & disease 2020 Jun 25;11(6):488
Cell death & disease 2020 Jun 25;11(6):488
Galangin Protects against Symptoms of Dextran Sodium Sulfate-induced Acute Colitis by Activating Autophagy and Modulating the Gut Microbiota.
Xuan H, Ou A, Hao S, Shi J, Jin X
Nutrients 2020 Jan 29;12(2)
Nutrients 2020 Jan 29;12(2)
The Preparation of Ginsenoside Rg5, Its Antitumor Activity against Breast Cancer Cells and Its Targeting of PI3K.
Liu Y, Fan D
Nutrients 2020 Jan 18;12(1)
Nutrients 2020 Jan 18;12(1)
Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1-dependent mitophagy in a Salmonella infantis model of piglet diarrhea.
Xia B, Yu J, He T, Liu X, Su J, Wang M, Wang J, Zhu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2821-2839
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Feb;34(2):2821-2839
α-synuclein promotes progression of Parkinson's disease by upregulating autophagy signaling pathway to activate NLRP3 inflammasome.
Wang X, Chi J, Huang D, Ding L, Zhao X, Jiang L, Yu Y, Gao F
Experimental and therapeutic medicine 2020 Feb;19(2):931-938
Experimental and therapeutic medicine 2020 Feb;19(2):931-938
High mobility group box 1 antibody represses autophagy and alleviates hippocampus damage in pilocarpine-induced mouse epilepsy model.
Ying C, Ying L, Yanxia L, Le W, Lili C
Acta histochemica 2020 Feb;122(2):151485
Acta histochemica 2020 Feb;122(2):151485
MDM2 inhibition-mediated autophagy contributes to the pro-apoptotic effect of berberine in p53-null leukemic cells.
Liu J, Zhu Z, Liu Y, Wei L, Li B, Mao F, Zhang J, Wang Y, Liu Y
Life sciences 2020 Feb 1;242:117228
Life sciences 2020 Feb 1;242:117228
Latcripin-7A, derivative of Lentinula edodes C(91-3), reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G(1) phase in breast cancer cells.
Din SRU, Zhong M, Nisar MA, Saleem MZ, Hussain A, Khinsar KH, Alam S, Ayub G, Kanwal S, Li X, Zhang W, Wang X, Ning A, Cao J, Huang M
Applied microbiology and biotechnology 2020 Dec;104(23):10165-10179
Applied microbiology and biotechnology 2020 Dec;104(23):10165-10179
Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress-autophagy axis and improves myocardial reconstruction after acute myocardial infarction.
Li Y, Liu M, Yi J, Song X, Zheng X, Liu D, Wang S, Chu C, Yang J
Acta biochimica et biophysica Sinica 2020 Dec 29;52(12):1325-1336
Acta biochimica et biophysica Sinica 2020 Dec 29;52(12):1325-1336
Graphene oxide size-dependently altered lipid profiles in THP-1 macrophages.
Luo Y, Peng J, Huang C, Cao Y
Ecotoxicology and environmental safety 2020 Aug;199:110714
Ecotoxicology and environmental safety 2020 Aug;199:110714
S100A8 transported by SEC23A inhibits metastatic colonization via autocrine activation of autophagy.
Sun Z, Zeng B, Liu D, Zhao Q, Wang J, Rosie Xing H
Cell death & disease 2020 Aug 6;11(8):650
Cell death & disease 2020 Aug 6;11(8):650
Butyrate-mediated autophagy inhibition limits cytosolic Salmonella Infantis replication in the colon of pigs treated with a mixture of Lactobacillus and Bacillus.
Chu B, Zhu Y, Su J, Xia B, Zou Y, Nie J, Zhang W, Wang J
Veterinary research 2020 Aug 5;51(1):99
Veterinary research 2020 Aug 5;51(1):99
Lactobacillus johnsonii L531 Ameliorates Escherichia coli-Induced Cell Damage via Inhibiting NLRP3 Inflammasome Activity and Promoting ATG5/ATG16L1-Mediated Autophagy in Porcine Mammary Epithelial Cells.
Zou YJ, Xu JJ, Wang X, Zhu YH, Wu Q, Wang JF
Veterinary sciences 2020 Aug 14;7(3)
Veterinary sciences 2020 Aug 14;7(3)
Loss of Mitochondrial DNA by Gemcitabine Triggers Mitophagy and Cell Death.
Inamura A, Muraoka-Hirayama S, Sakurai K
Biological & pharmaceutical bulletin 2019;42(12):1977-1987
Biological & pharmaceutical bulletin 2019;42(12):1977-1987
Mangiferin Prevents TBHP-Induced Apoptosis and ECM Degradation in Mouse Osteoarthritic Chondrocytes via Restoring Autophagy and Ameliorates Murine Osteoarthritis.
Li Y, Wu Y, Jiang K, Han W, Zhang J, Xie L, Liu Y, Xiao J, Wang X
Oxidative medicine and cellular longevity 2019;2019:8783197
Oxidative medicine and cellular longevity 2019;2019:8783197
LncRNA expression profile during autophagy and Malat1 function in macrophages.
Ma Z, Zhang J, Xu X, Qu Y, Dong H, Dang J, Huo Z, Xu G
PloS one 2019;14(8):e0221104
PloS one 2019;14(8):e0221104
The ginsenoside Rk3 exerts anti-esophageal cancer activity in vitro and in vivo by mediating apoptosis and autophagy through regulation of the PI3K/Akt/mTOR pathway.
Liu H, Zhao J, Fu R, Zhu C, Fan D
PloS one 2019;14(5):e0216759
PloS one 2019;14(5):e0216759
Autophagy: a new mechanism for regulating VEGF and PEDF expression in retinal pigment epithelium cells.
Li R, Du JH, Yao GM, Yao Y, Zhang J
International journal of ophthalmology 2019;12(4):557-562
International journal of ophthalmology 2019;12(4):557-562
Fish Autophagy Protein 5 Exerts Negative Regulation on Antiviral Immune Response Against Iridovirus and Nodavirus.
Li C, Liu J, Zhang X, Wei S, Huang X, Huang Y, Wei J, Qin Q
Frontiers in immunology 2019;10:517
Frontiers in immunology 2019;10:517
Pterostilbene, An Active Constituent of Blueberries, Suppresses Proliferation Potential of Human Cholangiocarcinoma via Enhancing the Autophagic Flux.
Wang D, Guo H, Yang H, Wang D, Gao P, Wei W
Frontiers in pharmacology 2019;10:1238
Frontiers in pharmacology 2019;10:1238
Sequential formation of different layers of dystrophic neurites in Alzheimer's brains.
Sharoar MG, Hu X, Ma XM, Zhu X, Yan R
Molecular psychiatry 2019 Sep;24(9):1369-1382
Molecular psychiatry 2019 Sep;24(9):1369-1382
Sodium fluoride regulates the osteo/odontogenic differentiation of stem cells from apical papilla by modulating autophagy.
Pan Y, Li Z, Wang Y, Yan M, Wu J, Beharee RG, Yu J
Journal of cellular physiology 2019 Sep;234(9):16114-16124
Journal of cellular physiology 2019 Sep;234(9):16114-16124
Effects of long-term fluoride exposure on cognitive ability and the underlying mechanisms: Role of autophagy and its association with apoptosis.
Zhou G, Tang S, Yang L, Niu Q, Chen J, Xia T, Wang S, Wang M, Zhao Q, Liu L, Li P, Dong L, Yang K, Zhang S, Wang A
Toxicology and applied pharmacology 2019 Sep 1;378:114608
Toxicology and applied pharmacology 2019 Sep 1;378:114608
Ginsenoside Rg5 induces G2/M phase arrest, apoptosis and autophagy via regulating ROS-mediated MAPK pathways against human gastric cancer.
Liu Y, Fan D
Biochemical pharmacology 2019 Oct;168:285-304
Biochemical pharmacology 2019 Oct;168:285-304
Homocysteine induces human mesangial cell apoptosis via the involvement of autophagy and endoplasmic reticulum stress.
Liang S, Liu H, Liu S, Wei M, Gao F, Xue J, Sun L, Wang M, Jiang H, Chen L
RSC advances 2019 Oct 1;9(54):31720-31727
RSC advances 2019 Oct 1;9(54):31720-31727
Icariin induces apoptosis by suppressing autophagy in tamoxifen-resistant breast cancer cell line MCF-7/TAM.
Cheng X, Tan S, Duan F, Yuan Q, Li Q, Deng G
Breast cancer (Tokyo, Japan) 2019 Nov;26(6):766-775
Breast cancer (Tokyo, Japan) 2019 Nov;26(6):766-775
Adiponectin inhibits high glucose-induced angiogenesis via inhibiting autophagy in RF/6A cells.
Li R, Du J, Yao Y, Yao G, Wang X
Journal of cellular physiology 2019 Nov;234(11):20566-20576
Journal of cellular physiology 2019 Nov;234(11):20566-20576
Promising therapeutic effect of thapsigargin nanoparticles on chronic kidney disease through the activation of Nrf2 and FoxO1.
Cheng FY, Lee YH, Hsu YH, Chiu IJ, Chiu YJ, Lin YF, Chiu HW
Aging 2019 Nov 12;11(21):9875-9892
Aging 2019 Nov 12;11(21):9875-9892
Roles of mitochondrial fission inhibition in developmental fluoride neurotoxicity: mechanisms of action in vitro and associations with cognition in rats and children.
Zhao Q, Niu Q, Chen J, Xia T, Zhou G, Li P, Dong L, Xu C, Tian Z, Luo C, Liu L, Zhang S, Wang A
Archives of toxicology 2019 Mar;93(3):709-726
Archives of toxicology 2019 Mar;93(3):709-726
Repression of MicroRNA-30e by Hepatitis C Virus Enhances Fatty Acid Synthesis.
Sasaki R, Sur S, Cheng Q, Steele R, Ray RB
Hepatology communications 2019 Jul;3(7):943-953
Hepatology communications 2019 Jul;3(7):943-953
The exosome-like vesicles from osteoarthritic chondrocyte enhanced mature IL-1β production of macrophages and aggravated synovitis in osteoarthritis.
Ni Z, Kuang L, Chen H, Xie Y, Zhang B, Ouyang J, Wu J, Zhou S, Chen L, Su N, Tan Q, Luo X, Chen B, Chen S, Yin L, Huang H, Du X, Chen L
Cell death & disease 2019 Jul 8;10(7):522
Cell death & disease 2019 Jul 8;10(7):522
Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation.
Zhong S, Li L, Zhang YL, Zhang L, Lu J, Guo S, Liang N, Ge J, Zhu M, Tao Y, Wu YC, Yin H
The Journal of clinical investigation 2019 Jan 2;129(1):252-267
The Journal of clinical investigation 2019 Jan 2;129(1):252-267
Hypothermic oxygenated machine perfusion alleviates liver injury in donation after circulatory death through activating autophagy in mice.
Zeng X, Wang S, Li S, Yang Y, Fang Z, Huang H, Wang Y, Fan X, Ye Q
Artificial organs 2019 Dec;43(12):E320-E332
Artificial organs 2019 Dec;43(12):E320-E332
Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy.
Cai Q, Wang S, Jin L, Weng M, Zhou D, Wang J, Tang Z, Quan Z
Molecular cancer 2019 Apr 5;18(1):82
Molecular cancer 2019 Apr 5;18(1):82
Autophagy exerts pivotal roles in regulatory effects of 1α,25-(OH)(2)D(3) on the osteoclastogenesis.
Ji L, Gao J, Kong R, Gao Y, Ji X, Zhao D
Biochemical and biophysical research communications 2019 Apr 16;511(4):869-874
Biochemical and biophysical research communications 2019 Apr 16;511(4):869-874
Autophagy Mediates Interleukin-1β Secretion in Human Neutrophils.
Iula L, Keitelman IA, Sabbione F, Fuentes F, Guzman M, Galletti JG, Gerber PP, Ostrowski M, Geffner JR, Jancic CC, Trevani AS
Frontiers in immunology 2018;9:269
Frontiers in immunology 2018;9:269
Promyelocytic Leukemia Restricts Enterovirus 71 Replication by Inhibiting Autophagy.
Chen D, Feng C, Tian X, Zheng N, Wu Z
Frontiers in immunology 2018;9:1268
Frontiers in immunology 2018;9:1268
MicroRNA-9a-5p Alleviates Ischemia Injury After Focal Cerebral Ischemia of the Rat by Targeting ATG5-Mediated Autophagy.
Wang N, Yang L, Zhang H, Lu X, Wang J, Cao Y, Chen L, Wang X, Cong L, Li J, Wang N, Liu Z, Wang L
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;45(1):78-87
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;45(1):78-87
Autophagy activation and the mechanism of retinal microvascular endothelial cells in hypoxia.
Li R, Wang LZ, Du JH, Zhao L, Yao Y
International journal of ophthalmology 2018;11(4):567-574
International journal of ophthalmology 2018;11(4):567-574
Resveratrol relieves particulate matter (mean diameter < 2.5 μm)-induced oxidative injury of lung cells through attenuation of autophagy deregulation.
Li Y, Qian W, Wang D, Meng Y, Wang X, Chen Y, Li X, Xie C, Zhong C, Fu S
Journal of applied toxicology : JAT 2018 Sep;38(9):1251-1261
Journal of applied toxicology : JAT 2018 Sep;38(9):1251-1261
LP1 from Lentinula edodes C(91-3) Induces Autophagy, Apoptosis and Reduces Metastasis in Human Gastric Cancer Cell Line SGC-7901.
Batool S, Joseph TP, Hussain M, Vuai MS, Khinsar KH, Din SRU, Padhiar AA, Zhong M, Ning A, Zhang W, Cao J, Huang M
International journal of molecular sciences 2018 Sep 30;19(10)
International journal of molecular sciences 2018 Sep 30;19(10)
Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.
Liu Y, Fan D
Food & function 2018 Nov 14;9(11):5513-5527
Food & function 2018 Nov 14;9(11):5513-5527
RAB37 interacts directly with ATG5 and promotes autophagosome formation via regulating ATG5-12-16 complex assembly.
Sheng Y, Song Y, Li Z, Wang Y, Lin H, Cheng H, Zhou R
Cell death and differentiation 2018 May;25(5):918-934
Cell death and differentiation 2018 May;25(5):918-934
7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway.
Tsai TC, Lai KH, Su JH, Wu YJ, Sheu JH
Marine drugs 2018 Mar 26;16(4)
Marine drugs 2018 Mar 26;16(4)
Retigabine ameliorates acute stress-induced impairment of spatial memory retrieval through regulating USP2 signaling pathways in hippocampal CA1 area.
Li C, Zhang J, Xu H, Chang M, Lv C, Xue W, Song Z, Zhang L, Zhang X, Tian X
Neuropharmacology 2018 Jun;135:151-162
Neuropharmacology 2018 Jun;135:151-162
Autophagy defects and related genetic variations in renal cell carcinoma with eosinophilic cytoplasmic inclusions.
Yu Z, Ma J, Li X, Liu Y, Li M, Wang L, Zhao M, He H, Zhang Y, Rao Q, Zhao D, Wang Y, Fan L, Li P, Liu Y, Liu F, Zhang F, Ye J, Yan Q, Guo S, Wang Z
Scientific reports 2018 Jul 2;8(1):9972
Scientific reports 2018 Jul 2;8(1):9972
CXCR4-mediated signaling regulates autophagy and influences acute myeloid leukemia cell survival and drug resistance.
Hu X, Mei S, Meng W, Xue S, Jiang L, Yang Y, Hui L, Chen Y, Guan MX
Cancer letters 2018 Jul 1;425:1-12
Cancer letters 2018 Jul 1;425:1-12
Antagonizing peroxisome proliferator-activated receptor γ facilitates M1-to-M2 shift of microglia by enhancing autophagy via the LKB1-AMPK signaling pathway.
Ji J, Xue TF, Guo XD, Yang J, Guo RB, Wang J, Huang JY, Zhao XJ, Sun XL
Aging cell 2018 Aug;17(4):e12774
Aging cell 2018 Aug;17(4):e12774
The gastric mucosal protective effects of astragaloside IV in mnng-induced GPL rats.
Cai T, Zhang C, Zhao Z, Li S, Cai H, Chen X, Cai D, Liu W, Yan Y, Xie K, Pan H, Zeng X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:291-299
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:291-299
Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling.
Liu M, Liang K, Zhen J, Zhou M, Wang X, Wang Z, Wei X, Zhang Y, Sun Y, Zhou Z, Su H, Zhang C, Li N, Gao C, Peng J, Yi F
Nature communications 2017 Sep 4;8(1):413
Nature communications 2017 Sep 4;8(1):413
SYNJ2BP promotes the degradation of PTEN through the lysosome-pathway and enhances breast tumor metastasis via PI3K/AKT/SNAI1 signaling.
Wang M, Wu H, Li S, Xu Z, Li X, Yang Y, Li B, Li Y, Guo J, Chen H
Oncotarget 2017 Oct 27;8(52):89692-89706
Oncotarget 2017 Oct 27;8(52):89692-89706
Fluoride-Induced Autophagy via the Regulation of Phosphorylation of Mammalian Targets of Rapamycin in Mice Leydig Cells.
Zhang J, Zhu Y, Shi Y, Han Y, Liang C, Feng Z, Zheng H, Eng M, Wang J
Journal of agricultural and food chemistry 2017 Oct 11;65(40):8966-8976
Journal of agricultural and food chemistry 2017 Oct 11;65(40):8966-8976
ATF4/ATG5 Signaling in Hypothalamic Proopiomelanocortin Neurons Regulates Fat Mass via Affecting Energy Expenditure.
Xiao Y, Deng Y, Yuan F, Xia T, Liu H, Li Z, Liu Z, Ying H, Liu Y, Zhai Q, Chen S, Guo F
Diabetes 2017 May;66(5):1146-1158
Diabetes 2017 May;66(5):1146-1158
Anti-osteoclastogenesis of Mineral Trioxide Aggregate through Inhibition of the Autophagic Pathway.
Cheng X, Zhu L, Zhang J, Yu J, Liu S, Lv F, Lin Y, Liu G, Peng B
Journal of endodontics 2017 May;43(5):766-773
Journal of endodontics 2017 May;43(5):766-773
TNF-α stimulates endothelial palmitic acid transcytosis and promotes insulin resistance.
Li W, Yang X, Zheng T, Xing S, Wu Y, Bian F, Wu G, Li Y, Li J, Bai X, Wu D, Jia X, Wang L, Zhu L, Jin S
Scientific reports 2017 Mar 17;7:44659
Scientific reports 2017 Mar 17;7:44659
7-O-geranylquercetin-induced autophagy contributes to apoptosis via ROS generation in human non-small cell lung cancer cells.
Wang EX, Zou BY, Shi L, Du LY, Zhu YY, Jiang YM, Ma XD, Kang XH, Wang CY, Zhen YH, Sun LD
Life sciences 2017 Jul 1;180:102-113
Life sciences 2017 Jul 1;180:102-113
miR-130a upregulates mTOR pathway by targeting TSC1 and is transactivated by NF-κB in high-grade serous ovarian carcinoma.
Wang Y, Zhang X, Tang W, Lin Z, Xu L, Dong R, Li Y, Li J, Zhang Z, Li X, Zhao L, Wei JJ, Shao C, Kong B, Liu Z
Cell death and differentiation 2017 Dec;24(12):2089-2100
Cell death and differentiation 2017 Dec;24(12):2089-2100
Protease-activated receptor-2 promotes kidney tubular epithelial inflammation by inhibiting autophagy via the PI3K/Akt/mTOR signalling pathway.
Du C, Zhang T, Xiao X, Shi Y, Duan H, Ren Y
The Biochemical journal 2017 Aug 2;474(16):2733-2747
The Biochemical journal 2017 Aug 2;474(16):2733-2747
Low-Dose Endothelial-Monocyte-Activating Polypeptide-II Induced Autophagy by Down-Regulating miR-20a in U-87 and U-251 Glioma Cells.
Chen J, Liu L, Liu Y, Liu X, Qu C, Meng F, Ma J, Lin Y, Xue Y
Frontiers in cellular neuroscience 2016;10:128
Frontiers in cellular neuroscience 2016;10:128
Nanoparticle-facilitated autophagy inhibition promotes the efficacy of chemotherapeutics against breast cancer stem cells.
Sun R, Shen S, Zhang YJ, Xu CF, Cao ZT, Wen LP, Wang J
Biomaterials 2016 Oct;103:44-55
Biomaterials 2016 Oct;103:44-55
Autophagy-mediated clearance of ubiquitinated mutant huntingtin by graphene oxide.
Jin P, Wei P, Zhang Y, Lin J, Sha R, Hu Y, Zhang J, Zhou W, Yao H, Ren L, Yang JY, Liu Y, Wen L
Nanoscale 2016 Nov 10;8(44):18740-18750
Nanoscale 2016 Nov 10;8(44):18740-18750
Bifidobacterial recombinant thymidine kinase-ganciclovir gene therapy system induces FasL and TNFR2 mediated antitumor apoptosis in solid tumors.
Wang C, Ma Y, Hu Q, Xie T, Wu J, Zeng F, Song F
BMC cancer 2016 Jul 27;16:545
BMC cancer 2016 Jul 27;16:545
Quinones Derived from Polychlorinated Biphenyls Induce ROS-Dependent Autophagy by Evoking an Autophagic Flux and Inhibition of mTOR/p70S6k.
Shi Q, Song X, Liu Z, Wang Y, Wang Y, Fu J, Su C, Xia X, Song E, Song Y
Chemical research in toxicology 2016 Jul 18;29(7):1160-71
Chemical research in toxicology 2016 Jul 18;29(7):1160-71
Interplay of autophagy and apoptosis during PRRSV infection of Marc145 cell.
Li S, Zhou A, Wang J, Zhang S
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2016 Apr;39:51-54
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2016 Apr;39:51-54
Anti-osteoclastogenic activity of isoliquiritigenin via inhibition of NF-κB-dependent autophagic pathway.
Liu S, Zhu L, Zhang J, Yu J, Cheng X, Peng B
Biochemical pharmacology 2016 Apr 15;106:82-93
Biochemical pharmacology 2016 Apr 15;106:82-93
Upregulation of ATG3 contributes to autophagy induced by the detachment of intestinal epithelial cells from the extracellular matrix, but promotes autophagy-independent apoptosis of the attached cells.
Yoo BH, Zagryazhskaya A, Li Y, Koomson A, Khan IA, Sasazuki T, Shirasawa S, Rosen KV
Autophagy 2015;11(8):1230-46
Autophagy 2015;11(8):1230-46
Expression of autophagy-related proteins ATG5 and FIP200 predicts favorable disease-free survival in patients with breast cancer.
Wang L, Yao L, Zheng YZ, Xu Q, Liu XP, Hu X, Wang P, Shao ZM
Biochemical and biophysical research communications 2015 Mar 20;458(4):816-22
Biochemical and biophysical research communications 2015 Mar 20;458(4):816-22
Connexin 31.1 degradation requires the Clathrin-mediated autophagy in NSCLC cell H1299.
Zhu X, Ruan Z, Yang X, Chu K, Wu H, Li Y, Huang Y
Journal of cellular and molecular medicine 2015 Jan;19(1):257-64
Journal of cellular and molecular medicine 2015 Jan;19(1):257-64
Potent effects of dioscin against obesity in mice.
Liu M, Xu L, Yin L, Qi Y, Xu Y, Han X, Zhao Y, Sun H, Yao J, Lin Y, Liu K, Peng J
Scientific reports 2015 Jan 22;5:7973
Scientific reports 2015 Jan 22;5:7973
Suppression of autophagy augments the radiosensitizing effects of STAT3 inhibition on human glioma cells.
Yuan X, Du J, Hua S, Zhang H, Gu C, Wang J, Yang L, Huang J, Yu J, Liu F
Experimental cell research 2015 Jan 15;330(2):267-276
Experimental cell research 2015 Jan 15;330(2):267-276
Differential ERK activation during autophagy induced by europium hydroxide nanorods and trehalose: Maximum clearance of huntingtin aggregates through combined treatment.
Wei PF, Jin PP, Barui AK, Hu Y, Zhang L, Zhang JQ, Shi SS, Zhang HR, Lin J, Zhou W, Zhang YJ, Ruan RQ, Patra CR, Wen LP
Biomaterials 2015 Dec;73:160-74
Biomaterials 2015 Dec;73:160-74
Atg5 but not Atg7 in dendritic cells enhances IL-2 and IFN-γ production by Toxoplasma gondii-reactive CD4+ T cells.
Liu E, Van Grol J, Subauste CS
Microbes and infection 2015 Apr;17(4):275-84
Microbes and infection 2015 Apr;17(4):275-84
Effects of the total saponins from Rosa laevigata Michx fruit against acetaminophen-induced liver damage in mice via induction of autophagy and suppression of inflammation and apoptosis.
Dong D, Xu L, Han X, Qi Y, Xu Y, Yin L, Liu K, Peng J
Molecules (Basel, Switzerland) 2014 May 30;19(6):7189-206
Molecules (Basel, Switzerland) 2014 May 30;19(6):7189-206
Japanese encephalitis virus activates autophagy as a viral immune evasion strategy.
Jin R, Zhu W, Cao S, Chen R, Jin H, Liu Y, Wang S, Wang W, Xiao G
PloS one 2013;8(1):e52909
PloS one 2013;8(1):e52909
Piperlongumine induces autophagy by targeting p38 signaling.
Wang Y, Wang JW, Xiao X, Shan Y, Xue B, Jiang G, He Q, Chen J, Xu HG, Zhao RX, Werle KD, Cui R, Liang J, Li YL, Xu ZX
Cell death & disease 2013 Oct 3;4(10):e824
Cell death & disease 2013 Oct 3;4(10):e824
Syntaxin 13, a genetic modifier of mutant CHMP2B in frontotemporal dementia, is required for autophagosome maturation.
Lu Y, Zhang Z, Sun D, Sweeney ST, Gao FB
Molecular cell 2013 Oct 24;52(2):264-71
Molecular cell 2013 Oct 24;52(2):264-71
P38 MAP kinase functions as a switch in MS-275-induced reactive oxygen species-dependent autophagy and apoptosis in human colon cancer cells.
Zhan Y, Gong K, Chen C, Wang H, Li W
Free radical biology & medicine 2012 Aug 1;53(3):532-43
Free radical biology & medicine 2012 Aug 1;53(3):532-43
Subversion of cellular autophagy machinery by hepatitis B virus for viral envelopment.
Li J, Liu Y, Wang Z, Liu K, Wang Y, Liu J, Ding H, Yuan Z
Journal of virology 2011 Jul;85(13):6319-33
Journal of virology 2011 Jul;85(13):6319-33
The CD40-autophagy pathway is needed for host protection despite IFN-Γ-dependent immunity and CD40 induces autophagy via control of P21 levels.
Portillo JA, Okenka G, Reed E, Subauste A, Van Grol J, Gentil K, Komatsu M, Tanaka K, Landreth G, Levine B, Subauste CS
PloS one 2010 Dec 31;5(12):e14472
PloS one 2010 Dec 31;5(12):e14472
Autophagy is essential for mitochondrial clearance in mature T lymphocytes.
Pua HH, Guo J, Komatsu M, He YW
Journal of immunology (Baltimore, Md. : 1950) 2009 Apr 1;182(7):4046-55
Journal of immunology (Baltimore, Md. : 1950) 2009 Apr 1;182(7):4046-55
A plant triterpenoid, avicin D, induces autophagy by activation of AMP-activated protein kinase.
Xu ZX, Liang J, Haridas V, Gaikwad A, Connolly FP, Mills GB, Gutterman JU
Cell death and differentiation 2007 Nov;14(11):1948-57
Cell death and differentiation 2007 Nov;14(11):1948-57
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse kidney tissue were subjected to SDS PAGE followed by western blot with 10181-2-AP(ATG5 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 10181-2-AP(ATG5 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
