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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [15]
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- Product number
- AP1812a - Provider product page
- Provider
- Abcepta
- Proper citation
- Abgent Cat#AP1812a, RRID:AB_2258842
- Product name
- ATG5 Antibody (N-term)
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- Purified Rabbit Polyclonal Antibody (Pab)
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 400 µl
- Concentration
- 2 mg/ml
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Autophagy induced by tumor necrosis factor α mediates intrinsic apoptosis in trophoblastic cells.
Long-term artificial selection reveals a role of TCTP in autophagy in mammalian cells.
Coxsackievirus B3 induces crosstalk between autophagy and apoptosis to benefit its release after replicating in autophagosomes through a mechanism involving caspase cleavage of autophagy-related proteins.
Down-regulation of autophagy-related protein 5 (ATG5) contributes to the pathogenesis of early-stage cutaneous melanoma.
Cell loss and autophagy in the extra-adrenal chromaffin organ of Zuckerkandl are regulated by glucocorticoid signalling.
Phosphorylation of Atg5 by the Gadd45β-MEKK4-p38 pathway inhibits autophagy.
Arsenic trioxide enhances the radiation sensitivity of androgen-dependent and -independent human prostate cancer cells.
Arsenic trioxide induces autophagy and apoptosis in human glioma cells in vitro and in vivo through downregulation of survivin.
p62, Ref(2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects.
A rapid method to improve protein detection by indirect ELISA.
Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy.
Expression pattern and functions of autophagy-related gene atg5 in zebrafish organogenesis.
Autophagy induced by deficiency of sphingosine-1-phosphate phosphohydrolase 1 is switched to apoptosis by calpain-mediated autophagy-related gene 5 (Atg5) cleavage.
Control of basal autophagy by calpain1 mediated cleavage of ATG5.
An increase in intracellular Ca2+ is required for the activation of mitochondrial calpain to release AIF during cell death.
Cha HH, Hwang JR, Kim HY, Choi SJ, Oh SY, Roh CR
Reproductive sciences (Thousand Oaks, Calif.) 2014 May;21(5):612-22
Reproductive sciences (Thousand Oaks, Calif.) 2014 May;21(5):612-22
Long-term artificial selection reveals a role of TCTP in autophagy in mammalian cells.
Chen K, Huang C, Yuan J, Cheng H, Zhou R
Molecular biology and evolution 2014 Aug;31(8):2194-211
Molecular biology and evolution 2014 Aug;31(8):2194-211
Coxsackievirus B3 induces crosstalk between autophagy and apoptosis to benefit its release after replicating in autophagosomes through a mechanism involving caspase cleavage of autophagy-related proteins.
Xin L, Xiao Z, Ma X, He F, Yao H, Liu Z
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2014 Aug;26:95-102
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2014 Aug;26:95-102
Down-regulation of autophagy-related protein 5 (ATG5) contributes to the pathogenesis of early-stage cutaneous melanoma.
Liu H, He Z, von Rütte T, Yousefi S, Hunger RE, Simon HU
Science translational medicine 2013 Sep 11;5(202):202ra123
Science translational medicine 2013 Sep 11;5(202):202ra123
Cell loss and autophagy in the extra-adrenal chromaffin organ of Zuckerkandl are regulated by glucocorticoid signalling.
Schober A, Parlato R, Huber K, Kinscherf R, Hartleben B, Huber TB, Schütz G, Unsicker K
Journal of neuroendocrinology 2013 Jan;25(1):34-47
Journal of neuroendocrinology 2013 Jan;25(1):34-47
Phosphorylation of Atg5 by the Gadd45β-MEKK4-p38 pathway inhibits autophagy.
Keil E, Höcker R, Schuster M, Essmann F, Ueffing N, Hoffman B, Liebermann DA, Pfeffer K, Schulze-Osthoff K, Schmitz I
Cell death and differentiation 2013 Feb;20(2):321-32
Cell death and differentiation 2013 Feb;20(2):321-32
Arsenic trioxide enhances the radiation sensitivity of androgen-dependent and -independent human prostate cancer cells.
Chiu HW, Chen YA, Ho SY, Wang YJ
PloS one 2012;7(2):e31579
PloS one 2012;7(2):e31579
Arsenic trioxide induces autophagy and apoptosis in human glioma cells in vitro and in vivo through downregulation of survivin.
Chiu HW, Ho YS, Wang YJ
Journal of molecular medicine (Berlin, Germany) 2011 Sep;89(9):927-41
Journal of molecular medicine (Berlin, Germany) 2011 Sep;89(9):927-41
p62, Ref(2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects.
Bartlett BJ, Isakson P, Lewerenz J, Sanchez H, Kotzebue RW, Cumming RC, Harris GL, Nezis IP, Schubert DR, Simonsen A, Finley KD
Autophagy 2011 Jun;7(6):572-83
Autophagy 2011 Jun;7(6):572-83
A rapid method to improve protein detection by indirect ELISA.
Hnasko R, Lin A, McGarvey JA, Stanker LH
Biochemical and biophysical research communications 2011 Jul 15;410(4):726-31
Biochemical and biophysical research communications 2011 Jul 15;410(4):726-31
Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy.
Lépine S, Allegood JC, Park M, Dent P, Milstien S, Spiegel S
Cell death and differentiation 2011 Feb;18(2):350-61
Cell death and differentiation 2011 Feb;18(2):350-61
Expression pattern and functions of autophagy-related gene atg5 in zebrafish organogenesis.
Hu Z, Zhang J, Zhang Q
Autophagy 2011 Dec;7(12):1514-27
Autophagy 2011 Dec;7(12):1514-27
Autophagy induced by deficiency of sphingosine-1-phosphate phosphohydrolase 1 is switched to apoptosis by calpain-mediated autophagy-related gene 5 (Atg5) cleavage.
Lépine S, Allegood JC, Edmonds Y, Milstien S, Spiegel S
The Journal of biological chemistry 2011 Dec 30;286(52):44380-90
The Journal of biological chemistry 2011 Dec 30;286(52):44380-90
Control of basal autophagy by calpain1 mediated cleavage of ATG5.
Xia HG, Zhang L, Chen G, Zhang T, Liu J, Jin M, Ma X, Ma D, Yuan J
Autophagy 2010 Jan;6(1):61-6
Autophagy 2010 Jan;6(1):61-6
An increase in intracellular Ca2+ is required for the activation of mitochondrial calpain to release AIF during cell death.
Norberg E, Gogvadze V, Ott M, Horn M, Uhlén P, Orrenius S, Zhivotovsky B
Cell death and differentiation 2008 Dec;15(12):1857-64
Cell death and differentiation 2008 Dec;15(12):1857-64
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