GTX62601

antibody from GeneTex

Targeting: ATG5 APG5, APG5L, ASP, hAPG5

Provider product page for GTX62601

Western blot

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [7]
Comments [0]
Validations
Western blot [3]
Immunohistochemistry [1]

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Product number: GTX62601 - Provider product page
Provider: GeneTex
Proper citation: GeneTex Cat#GTX62601, RRID:AB_10627207
Product name: ATG5 antibody [EPR1755(2)]
Antibody type: Monoclonal
Reactivity: Human, Mouse, Rat
Host: Rabbit

ATG5 protein structure - GTX62601 shown in red.

Submitted references miR-30a Remodels Subcutaneous Adipose Tissue Inflammation to Improve Insulin Sensitivity in Obesity.

Koh EH, Chernis N, Saha PK, Xiao L, Bader DA, Zhu B, Rajapakshe K, Hamilton MP, Liu X, Perera D, Chen X, York B, Trauner M, Coarfa C, Bajaj M, Moore DD, Deng T, McGuire SE, Hartig SM
Diabetes 2018 Dec;67(12):2541-2553

Complement regulatory protein CD46 induces autophagy against oxidative stress-mediated apoptosis in normal and asthmatic airway epithelium.

Tsai YG, Wen YS, Wang JY, Yang KD, Sun HL, Liou JH, Lin CY
Scientific reports 2018 Aug 28;8(1):12973

Recycling and Endosomal Sorting of Protease-activated Receptor-1 Is Distinctly Regulated by Rab11A and Rab11B Proteins.

Grimsey NJ, Coronel LJ, Cordova IC, Trejo J
The Journal of biological chemistry 2016 Jan 29;291(5):2223-36

Sann-Joong-Kuey-Jian-Tang induces autophagy in HepG2 cells via regulation of the phosphoinositide-3 kinase/Akt/mammalian target of rapamycin and p38 mitogen-activated protein kinase pathways.

Chuang WL, Su CC, Lin PY, Lin CC, Chen YL
Molecular medicine reports 2015 Aug;12(2):1677-84

Mutations in the ubiquitin-binding domain of OPTN/optineurin interfere with autophagy-mediated degradation of misfolded proteins by a dominant-negative mechanism.

Shen WC, Li HY, Chen GC, Chern Y, Tu PH
Autophagy 2015 Apr 3;11(4):685-700

β-adrenergic receptor-stimulated lipolysis requires the RAB7-mediated autolysosomal lipid degradation.

Lizaso A, Tan KT, Lee YH
Autophagy 2013 Aug;9(8):1228-43

Enterovirus 71 infection cleaves a negative regulator for viral internal ribosomal entry site-driven translation.

Chen LL, Kung YA, Weng KF, Lin JY, Horng JT, Shih SR
Journal of virology 2013 Apr;87(7):3828-38

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Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: Western blot analysis on (A) Raji (B) HeLa (C) HT-1080 and (D) fetal kidney lysates using anti-Atg5 RabMAb (cat. #GTX62601).
Validation comment: WB

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: Western blot analysis on (A) C6 (B) Raw264.7 (C) PC-12 and (D) NIH/3T3 cell lysates using anti-Atg5 RabMAb (cat. #GTX62601).
Validation comment: WB

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: WB analysis of lysates from (1) Raji, (2) HeLa, (3) HT-1080, (4) human fetal kidney, (5) C6, (6) Raw264.7, (7) PC-12 and (8) NIH3T3 (10 £gg per lane) using Atg5 antibody [EPR1755(2)] at a dilution of 1:1,000.

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: IHC-P analysis of human ovarian adenocarcinoma tissue using Atg5 antibody [EPR1755(2)] at a dilution of 1:100.