Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations [0]
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- Product number
- M00240 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-ATG5/Apg5 Rabbit Monoclonal Antibody
- Antibody type
- Monoclonal
- Description
- Monoclonal antibody for APG5/ATG5 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IP, IF, IHC, ICC, WB. Reactive species: Human, Mouse, Rat APG5/ATG5 information: Molecular Weight: 32447 MW; Subcellular Localization: Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein. Colocalizes with nonmuscle actin. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed (By similarity). Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme; Tissue Specificity: Ubiquitous. The mRNA is present at similar levels in viable and apoptotic cells, whereas the protein is dramatically highly expressed in apoptotic cells.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Antibody clone number
- GCD-1
- Vial size
- 100ug/vial
- Concentration
- 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
- Storage
- At -20°C for one year. Avoid repeated freezing and thawing.
Submitted references NCX1/Ca(2+) promotes autophagy and decreases bortezomib activity in multiple myeloma through non-canonical NFκB signaling pathway.
Liensinine sensitizes colorectal cancer cells to oxaliplatin by targeting HIF-1α to inhibit autophagy.
1,3-Substituted β-Carboline Derivatives as Potent Chemotherapy for the Treatment of Cystic Echinococcosis.
rs2253820 Variant Controls Blood Pressure Dip After Stroke by Increasing CLOCK-BMAL1 Expression.
eIF3k inhibits NF-κB signaling by targeting MyD88 for ATG5-mediated autophagic degradation in teleost fish.
Synergistic Lysosomal Impairment and ER Stress Activation for Boosted Autophagy Dysfunction Based on Te Double-Headed Nano-Bullets.
DJ-1 activates the Atg5-Atg12-Atg16L1 complex via Sirt1 to influence microglial polarization and alleviate cerebral ischemia/reperfusion-induced inflammatory injury.
Dependence of glucose transport on autophagy and GAPDH activity.
Integrated metabolomics and mechanism to reveal the protective effect of kaempferol on pulmonary arterial hypertension.
Cardiac Glycoside Compound Isolated from Helleborus thibetanus Franch Displays Potent Toxicity against HeLa Cervical Carcinoma Cells through ROS-Independent Autophagy.
Andrographolide Induces Autophagic Cell Death and Inhibits Invasion and Metastasis of Human Osteosarcoma Cells in An Autophagy-Dependent Manner.
Tetrahydrocurcumin induces mesenchymal-epithelial transition and suppresses angiogenesis by targeting HIF-1α and autophagy in human osteosarcoma.
Li T, Xiao P, Qiu D, Yang A, Chen Q, Lin J, Liu Y, Chen J, Zeng Z
Cell communication and signaling : CCS 2024 May 6;22(1):258
Cell communication and signaling : CCS 2024 May 6;22(1):258
Liensinine sensitizes colorectal cancer cells to oxaliplatin by targeting HIF-1α to inhibit autophagy.
Feng Z, Zhang S, Han Q, Chu T, Wang H, Yu L, Zhang W, Liu J, Liang W, Xue J, Wu X, Zhang C, Wang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155647
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155647
1,3-Substituted β-Carboline Derivatives as Potent Chemotherapy for the Treatment of Cystic Echinococcosis.
Chen B, Wu J, Yan Z, Wu H, Gao H, Liu Y, Zhao J, Wang J, Yang J, Zhang Y, Pan J, Ling Y, Wen H, Huang Z
Journal of medicinal chemistry 2023 Dec 28;66(24):16680-16693
Journal of medicinal chemistry 2023 Dec 28;66(24):16680-16693
rs2253820 Variant Controls Blood Pressure Dip After Stroke by Increasing CLOCK-BMAL1 Expression.
He M, Li L, Li J, Chen S, Shi H
Translational stroke research 2023 Aug;14(4):472-489
Translational stroke research 2023 Aug;14(4):472-489
eIF3k inhibits NF-κB signaling by targeting MyD88 for ATG5-mediated autophagic degradation in teleost fish.
Chen Y, Cao B, Zheng W, Sun Y, Xu T
The Journal of biological chemistry 2022 Mar;298(3):101730
The Journal of biological chemistry 2022 Mar;298(3):101730
Synergistic Lysosomal Impairment and ER Stress Activation for Boosted Autophagy Dysfunction Based on Te Double-Headed Nano-Bullets.
Wang T, Xiao G, Lu Q, Zhou Y, Wang S, Liang X, Song Y, Xu M, Zhu Y, Li N
Small (Weinheim an der Bergstrasse, Germany) 2022 Jul;18(27):e2201585
Small (Weinheim an der Bergstrasse, Germany) 2022 Jul;18(27):e2201585
DJ-1 activates the Atg5-Atg12-Atg16L1 complex via Sirt1 to influence microglial polarization and alleviate cerebral ischemia/reperfusion-induced inflammatory injury.
Zhao N, Li Y, Wang C, Xue Y, Peng L, Wang T, Zhao Y, Xu G, Yu S
Neurochemistry international 2022 Jul;157:105341
Neurochemistry international 2022 Jul;157:105341
Dependence of glucose transport on autophagy and GAPDH activity.
Craven RJ, Frazier HN, Thibault O
Brain research 2022 Feb 1;1776:147747
Brain research 2022 Feb 1;1776:147747
Integrated metabolomics and mechanism to reveal the protective effect of kaempferol on pulmonary arterial hypertension.
Yi J, Wang X, Song K, Ren J, Che H, Yu H, Li Q
Journal of pharmaceutical and biomedical analysis 2022 Apr 1;212:114662
Journal of pharmaceutical and biomedical analysis 2022 Apr 1;212:114662
Cardiac Glycoside Compound Isolated from Helleborus thibetanus Franch Displays Potent Toxicity against HeLa Cervical Carcinoma Cells through ROS-Independent Autophagy.
Man S, Wang H, Zhou J, Lu Y, Su Y, Ma L
Chemical research in toxicology 2019 Dec 16;32(12):2479-2487
Chemical research in toxicology 2019 Dec 16;32(12):2479-2487
Andrographolide Induces Autophagic Cell Death and Inhibits Invasion and Metastasis of Human Osteosarcoma Cells in An Autophagy-Dependent Manner.
Liu Y, Zhang Y, Zou J, Yan L, Yu X, Lu P, Wu X, Li Q, Gu R, Zhu D
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(4):1396-1410
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(4):1396-1410
Tetrahydrocurcumin induces mesenchymal-epithelial transition and suppresses angiogenesis by targeting HIF-1α and autophagy in human osteosarcoma.
Zhang Y, Liu Y, Zou J, Yan L, Du W, Zhang Y, Sun H, Lu P, Geng S, Gu R, Zhang H, Bi Z
Oncotarget 2017 Oct 31;8(53):91134-91149
Oncotarget 2017 Oct 31;8(53):91134-91149
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