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CITED4
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4The protein encoded by this intronless gene belongs to the CITED family of transcriptional coactivators that bind to several proteins, including CREB-binding protein (CBP) and p300, via a conserved 32 aa C-terminal motif, and regulate gene transcription. This protein also interacts with transcription factor AP2 (TFAP2), and thus may function as a co-activator for TFAP2. Hypermethylation and transcriptional downregulation of this gene has been observed in oligodendroglial tumors with deletions of chromosomal arms 1p and 19q, and associated with longer recurrence-free and overall survival of patients with oligodendroglial tumors. [provided by RefSeq, Aug 2011]
Top validated antibodies |
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| Novus Biologicals |  NB110-41572 |
1 references | Monoclonal |
WB
EL
ICC
IP
IHC
FC
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| antibodies-online | ABIN188951 |
1 references | Monoclonal |
WB
EL
ICC
IP
IHC
FC
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| LSBio | LS-C134126 |
Monoclonal |
WB
EL
IHC
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| Abnova Corporation | H00163732-M08 |
Monoclonal |
WB
ICC
IHC
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| Invitrogen Antibodies | MA1-16984 |
Monoclonal |
WB
EL
IP
IHC
FC
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