Antibody data
- Antibody Data
- Antigen structure
- References [20]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Flow cytometry [1]
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Validation data
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- Product number
- 22399-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- Syntenin-1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Syntenin-1 antibody (Cat. #22399-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Isolation and characterization of small extracellular vesicles from murine primary mammary tumor.
SEVtras delineates small extracellular vesicles at droplet resolution from single-cell transcriptomes.
Exosome-Mediated Paracrine Signaling Unveils miR-1246 as a Driver of Aggressiveness in Fusion-Negative Rhabdomyosarcoma.
Presence of Intact Hepatitis B Virions in Exosomes.
Comparison of proteomic landscape of extracellular vesicles in pleural effusions isolated by three strategies.
Extracellular vesicles from Zika virus-infected cells display viral E protein that binds ZIKV-neutralizing antibodies to prevent infection enhancement.
Lysine butyrylation of HSP90 regulated by KAT8 and HDAC11 confers chemoresistance.
Tumor Necrosis Factor Alpha Preconditioned Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Enhance the Inhibition of Necroptosis of Acinar cells in Severe Acute Pancreatitis.
Exosomes from TNF-α preconditioned human umbilical cord mesenchymal stromal cells inhibit the autophagy of acinar cells of severe acute pancreatitis via shuttling bioactive metabolites.
Syntenin Regulated by miR-216b Promotes Cancer Progression in Pancreatic Cancer.
Intercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity.
Enterovirus 71-induced autophagosome fusion with multivesicular bodies facilitates viral RNA packaging into exosomes.
EV-miRome-wide profiling uncovers miR-320c for detecting metastatic colorectal cancer and monitoring the therapeutic response.
Circular RNA circNFATC3 acts as a miR-9-5p sponge to promote cervical cancer development by upregulating SDC2.
RAB31 marks and controls an ESCRT-independent exosome pathway.
Downregulation of exosomal miR‑1273a increases cisplatin resistance of non‑small cell lung cancer by upregulating the expression of syndecan binding protein.
Inhibitory effect of taspine derivative TAD1822-7 on tumor cell growth and angiogenesis via suppression of EphrinB2 and related signaling pathways.
Effects of Inhibiting VPS4 Support a General Role for ESCRTs in Extracellular Vesicle Biogenesis.
Berberine inhibits the proliferation and migration of breast cancer ZR-75-30 cells by targeting Ephrin-B2.
A taspine derivative supresses Caco-2 cell growth by competitively targeting EphrinB2 and regulating its pathway.
Hu S, Zhang X, Yan W
STAR protocols 2024 Mar 15;5(1):102783
STAR protocols 2024 Mar 15;5(1):102783
SEVtras delineates small extracellular vesicles at droplet resolution from single-cell transcriptomes.
He R, Zhu J, Ji P, Zhao F
Nature methods 2024 Feb;21(2):259-266
Nature methods 2024 Feb;21(2):259-266
Exosome-Mediated Paracrine Signaling Unveils miR-1246 as a Driver of Aggressiveness in Fusion-Negative Rhabdomyosarcoma.
Ramadan F, Saab R, Ghamloush F, Khoueiry R, Herceg Z, Gomez L, Badran B, Clezardin P, Hussein N, Cohen PA, Ghayad SE
Cancers 2024 Apr 25;16(9)
Cancers 2024 Apr 25;16(9)
Presence of Intact Hepatitis B Virions in Exosomes.
Wu Q, Glitscher M, Tonnemacher S, Schollmeier A, Raupach J, Zahn T, Eberle R, Krijnse-Locker J, Basic M, Hildt E
Cellular and molecular gastroenterology and hepatology 2023;15(1):237-259
Cellular and molecular gastroenterology and hepatology 2023;15(1):237-259
Comparison of proteomic landscape of extracellular vesicles in pleural effusions isolated by three strategies.
Yao X, Liao B, Chen F, Liu L, Wu K, Hao Y, Li Y, Wang Y, Fan R, Yin J, Liu L, Guo Y
Frontiers in bioengineering and biotechnology 2023;11:1108952
Frontiers in bioengineering and biotechnology 2023;11:1108952
Extracellular vesicles from Zika virus-infected cells display viral E protein that binds ZIKV-neutralizing antibodies to prevent infection enhancement.
Zhao F, Xu Y, Liu N, Lv D, Chen Y, Liu Z, Jin X, Xiao M, Lavillette D, Zhong J, Bartenschlager R, Long G
The EMBO journal 2023 Mar 15;42(6):e112096
The EMBO journal 2023 Mar 15;42(6):e112096
Lysine butyrylation of HSP90 regulated by KAT8 and HDAC11 confers chemoresistance.
He Y, Zheng CC, Yang J, Li SJ, Xu TY, Wei X, Chen WY, Jiang ZL, Xu JJ, Zhang GG, Cheng C, Chen KS, Shi XY, Qin DJ, Liu JB, Li B
Cell discovery 2023 Jul 18;9(1):74
Cell discovery 2023 Jul 18;9(1):74
Tumor Necrosis Factor Alpha Preconditioned Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Enhance the Inhibition of Necroptosis of Acinar cells in Severe Acute Pancreatitis.
Xie W, Luo T, Ma Z, Xue S, Jia X, Yang T, Song Z
Tissue engineering. Part A 2023 Dec;29(23-24):607-619
Tissue engineering. Part A 2023 Dec;29(23-24):607-619
Exosomes from TNF-α preconditioned human umbilical cord mesenchymal stromal cells inhibit the autophagy of acinar cells of severe acute pancreatitis via shuttling bioactive metabolites.
Ma Z, Xie W, Luo T, Hu Z, Hua J, Zhou J, Yang T, Wang W, Song Z, Yu X, Xu J, Shi S
Cellular and molecular life sciences : CMLS 2023 Aug 18;80(9):257
Cellular and molecular life sciences : CMLS 2023 Aug 18;80(9):257
Syntenin Regulated by miR-216b Promotes Cancer Progression in Pancreatic Cancer.
Zu F, Chen H, Liu Q, Zang H, Li Z, Tan X
Frontiers in oncology 2022;12:790788
Frontiers in oncology 2022;12:790788
Intercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity.
Gao Y, Zheng X, Chang B, Lin Y, Huang X, Wang W, Ding S, Zhan W, Wang S, Xiao B, Huo L, Yu Y, Chen Y, Gong R, Wu Y, Zhang R, Zhong L, Wang X, Chen Q, Gao S, Jiang Z, Wei D, Kang T
Cell research 2022 Dec;32(12):1086-1104
Cell research 2022 Dec;32(12):1086-1104
Enterovirus 71-induced autophagosome fusion with multivesicular bodies facilitates viral RNA packaging into exosomes.
Zhang R, Chen J, Zi R, Ji L, Hu J, Wu Z, Fu Y
Microbial pathogenesis 2022 Dec;173(Pt A):105875
Microbial pathogenesis 2022 Dec;173(Pt A):105875
EV-miRome-wide profiling uncovers miR-320c for detecting metastatic colorectal cancer and monitoring the therapeutic response.
Yang CK, Hsu HC, Liu YH, Tsai WS, Ma CP, Chen YT, Tan BC, Lai YY, Chang IY, Yang C, Yang CY, Yu JS, Liu H
Cellular oncology (Dordrecht, Netherlands) 2022 Aug;45(4):621-638
Cellular oncology (Dordrecht, Netherlands) 2022 Aug;45(4):621-638
Circular RNA circNFATC3 acts as a miR-9-5p sponge to promote cervical cancer development by upregulating SDC2.
Ma N, Li X, Wei H, Zhang H, Zhang S
Cellular oncology (Dordrecht, Netherlands) 2021 Feb;44(1):93-107
Cellular oncology (Dordrecht, Netherlands) 2021 Feb;44(1):93-107
RAB31 marks and controls an ESCRT-independent exosome pathway.
Wei D, Zhan W, Gao Y, Huang L, Gong R, Wang W, Zhang R, Wu Y, Gao S, Kang T
Cell research 2021 Feb;31(2):157-177
Cell research 2021 Feb;31(2):157-177
Downregulation of exosomal miR‑1273a increases cisplatin resistance of non‑small cell lung cancer by upregulating the expression of syndecan binding protein.
Zhao X, Li M, Dai X, Yang Y, Peng Y, Xu C, Dai N, Wang D
Oncology reports 2020 Nov;44(5):2165-2173
Oncology reports 2020 Nov;44(5):2165-2173
Inhibitory effect of taspine derivative TAD1822-7 on tumor cell growth and angiogenesis via suppression of EphrinB2 and related signaling pathways.
Liu R, Yu R, Cui Y, Fan M, Wang B, Zhang Y
Acta pharmaceutica (Zagreb, Croatia) 2019 Sep 1;69(3):423-431
Acta pharmaceutica (Zagreb, Croatia) 2019 Sep 1;69(3):423-431
Effects of Inhibiting VPS4 Support a General Role for ESCRTs in Extracellular Vesicle Biogenesis.
Jackson CE, Scruggs BS, Schaffer JE, Hanson PI
Biophysical journal 2017 Sep 19;113(6):1342-1352
Biophysical journal 2017 Sep 19;113(6):1342-1352
Berberine inhibits the proliferation and migration of breast cancer ZR-75-30 cells by targeting Ephrin-B2.
Ma W, Zhu M, Zhang D, Yang L, Yang T, Li X, Zhang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2017 Feb 15;25:45-51
Phytomedicine : international journal of phytotherapy and phytopharmacology 2017 Feb 15;25:45-51
A taspine derivative supresses Caco-2 cell growth by competitively targeting EphrinB2 and regulating its pathway.
Dai B, Wang W, Ma Y, Liu R, Zhang Y
Oncology reports 2016 Sep;36(3):1526-34
Oncology reports 2016 Sep;36(3):1526-34
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 22399-1-AP(SDCBP antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-SDCBP (IP:22399-1-AP, 3ug; Detection:22399-1-AP 1:1000) with HeLa cells lysate 2500ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Syntenin 1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human Syntenin 1. This antibody recognizes human antigen. The Syntenin 1 antibody has been validated for the following applications: ELISA, WB, IP, IHC, FC analysis.