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antibody from Atlas Antibodies
Targeting: CHCHD3
FLJ20420, Mic19, MICOS19, MINOS3, PPP1R22
Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- HPA042935 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA042935, RRID:AB_10794538
- Product name
- Anti-CHCHD3
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human CHCHD3, Gene description: coiled-coil-helix-coiled-coil-helix domain containing 3, Alternative Gene Names: FLJ20420, MINOS3, PPP1R22, Validated applications: ICC, IHC, WB, Uniprot ID: Q9NX63, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.5 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Drosophila MIC10b can polymerize into cristae-shaping filaments.
Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations
Phosphodiesterase 2A2 regulates mitochondria clearance through Parkin-dependent mitophagy.
CHCHD2 accumulates in distressed mitochondria and facilitates oligomerization of CHCHD10
The presence of disulfide bonds reveals an evolutionarily conserved mechanism involved in mitochondrial protein translocase assembly.
Stephan T, Stoldt S, Barbot M, Carney TD, Lange F, Bates M, Bou Dib P, Inamdar K, Shcherbata HR, Meinecke M, Riedel D, Dennerlein S, Rehling P, Jakobs S
Life science alliance 2024 Apr;7(4)
Life science alliance 2024 Apr;7(4)
Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations
Narendra D, Sekine S, Poulton J, Springer D, Dombi E, Wu B, Shammas M, Nguyen D, Huang X, Liu Y
Human Molecular Genetics 2020;29(9):1547-1567
Human Molecular Genetics 2020;29(9):1547-1567
Phosphodiesterase 2A2 regulates mitochondria clearance through Parkin-dependent mitophagy.
Lobo MJ, Reverte-Salisa L, Chao YC, Koschinski A, Gesellchen F, Subramaniam G, Jiang H, Pace S, Larcom N, Paolocci E, Pfeifer A, Zanivan S, Zaccolo M
Communications biology 2020 Oct 21;3(1):596
Communications biology 2020 Oct 21;3(1):596
CHCHD2 accumulates in distressed mitochondria and facilitates oligomerization of CHCHD10
Huang X, Wu B, Nguyen D, Liu Y, Marani M, Hench J, Bénit P, Kozjak-Pavlovic V, Rustin P, Frank S, Narendra D
Human Molecular Genetics 2018
Human Molecular Genetics 2018
The presence of disulfide bonds reveals an evolutionarily conserved mechanism involved in mitochondrial protein translocase assembly.
Wrobel L, Sokol AM, Chojnacka M, Chacinska A
Scientific reports 2016 Jun 6;6:27484
Scientific reports 2016 Jun 6;6:27484
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Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Genetic validation
- Main image
- Experimental details
- Western blot analysis in U-87MG ATCC cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-CHCHD3 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.
- Sample type
- Human
- Protocol
- Protocol
