2997

antibody from Cell Signaling Technology, Inc

Targeting: AKT1S1 Lobe, MGC2865, PRAS40

Western blot (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

2997

Provider

Cell Signaling Technology, Inc

Proper citation

Cell Signaling Technology Cat#2997, RRID:AB_2258110

Product name

Phospho-PRAS40 (Thr246) (C77D7) Rabbit mAb

Antibody type

Monoclonal

Reactivity

Human, Mouse, Rat, Simian

Host

Rabbit

Storage

-20°C

References

Submitted references

Differential contribution of insulin and amino acids to the mTORC1-autophagy pathway in the liver and muscle.

Naito T, Kuma A, Mizushima N
The Journal of biological chemistry 2013 Jul 19;288(29):21074-81

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BIM expression in treatment-naive cancers predicts responsiveness to kinase inhibitors.

Faber AC, Corcoran RB, Ebi H, Sequist LV, Waltman BA, Chung E, Incio J, Digumarthy SR, Pollack SF, Song Y, Muzikansky A, Lifshits E, Roberge S, Coffman EJ, Benes CH, Gómez HL, Baselga J, Arteaga CL, Rivera MN, Dias-Santagata D, Jain RK, Engelman JA
Cancer discovery 2011 Sep;1(4):352-65

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Skeletal muscle dysfunction in muscle-specific LKB1 knockout mice.

Thomson DM, Hancock CR, Evanson BG, Kenney SG, Malan BB, Mongillo AD, Brown JD, Hepworth S, Fillmore N, Parcell AC, Kooyman DL, Winder WW
Journal of applied physiology (Bethesda, Md. : 1985) 2010 Jun;108(6):1775-85

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Pathway-based identification of biomarkers for targeted therapeutics: personalized oncology with PI3K pathway inhibitors.

Andersen JN, Sathyanarayanan S, Di Bacco A, Chi A, Zhang T, Chen AH, Dolinski B, Kraus M, Roberts B, Arthur W, Klinghoffer RA, Gargano D, Li L, Feldman I, Lynch B, Rush J, Hendrickson RC, Blume-Jensen P, Paweletz CP
Science translational medicine 2010 Aug 4;2(43):43ra55