ABIN406673

antibody from antibodies-online

Targeting: H2AX H2AFX

Western blot (Data presented on provider website)

Antibody Data

Product number

ABIN406673

Provider

antibodies-online

Product name

anti-H2A Histone Family, Member X (H2AFX) (N-Term) antibody

Antibody type

Polyclonal

Antigen

The immunogen for anti-H2AFX antibody: synthetic peptide directed towards the N terminal of human H2AFX

Description

Affinity Purified

Reactivity

Human, Mouse, Rat, Bovine, Canine, Porcine, Xenopus, Zebrafish

Host

Rabbit

Antigen sequence

SGRGKTGGKARAKAKSRSSRAGLQFPVGRVHRLLR
KGHYA ERVGAGAPVY


Epitope

N-Term

Vial size

50 μg

Concentration

1mg/mL

Storage

-20°C

Handling

Avoid repeated freeze-thaw cycles.

References

Submitted references

MST1 promotes apoptosis through phosphorylation of histone H2AX.

Wen W, Zhu F, Zhang J, Keum YS, Zykova T, Yao K, Peng C, Zheng D, Cho YY, Ma WY, Bode AM, Dong Z
The Journal of biological chemistry 2010 Dec 10;285(50):39108-16

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Accumulation of DSBs in gamma-H2AX domains fuel chromosomal aberrations.

Scherthan H, Hieber L, Braselmann H, Meineke V, Zitzelsberger H
Biochemical and biophysical research communications 2008 Jul 11;371(4):694-7