Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 10772-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10772-1-AP, RRID:AB_2192691
- Product name
- SNX3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SNX3 antibody (Cat. #10772-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references SNX-3 confers lysosomal fusion-competence to sustain basal autophagy.
Targeting sorting nexin 3 to treat pulmonary fibrosis by dual modulating Wnt/β-catenin signaling.
SNX3 mediates heart failure by interacting with HMGB1 and subsequently facilitating its nuclear-cytoplasmic translocation.
Contribution of Sorting Nexin 3 in the Cytomegalovirus Assembly.
HIF-1α/m(6)A/NF-κB/CCL3 axis-mediated immunosurveillance participates in low level benzene-related erythrohematopoietic development toxicity.
Sorting nexin 3 exacerbates doxorubicin-induced cardiomyopathy via regulation of TFRC-dependent ferroptosis.
EGF-SNX3-EGFR axis drives tumor progression and metastasis in triple-negative breast cancers.
Sorting nexin 3 induces heart failure via promoting retromer-dependent nuclear trafficking of STAT3.
MON2 Guides Wntless Transport to the Golgi through Recycling Endosomes.
SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion.
Label-free proteomic analysis of placental proteins during Toxoplasma gondii infection.
Class III phosphatidylinositol-3-OH kinase controls epithelial integrity through endosomal LKB1 regulation.
Kang Q, Liu Z, Xiang L, Yang S, Yi P, Zhang R
Cellular and molecular life sciences : CMLS 2026 Jan 15;83(1):85
Cellular and molecular life sciences : CMLS 2026 Jan 15;83(1):85
Targeting sorting nexin 3 to treat pulmonary fibrosis by dual modulating Wnt/β-catenin signaling.
Ma D, Yu W, Zhou H, Lin R, Sun X, Peng M, Lin C, Du H, Li Y, Liang H, Sun D, Liu P, Lu J
Cell death & disease 2026 Jan 15;17(1):43
Cell death & disease 2026 Jan 15;17(1):43
SNX3 mediates heart failure by interacting with HMGB1 and subsequently facilitating its nuclear-cytoplasmic translocation.
Li H, Peng MX, Yang RX, Chen JX, Wang YM, Wang PX, Hu YH, Pan DY, Liu PQ, Lu J
Acta pharmacologica Sinica 2025 Apr;46(4):964-975
Acta pharmacologica Sinica 2025 Apr;46(4):964-975
Contribution of Sorting Nexin 3 in the Cytomegalovirus Assembly.
Viduka I, Štimac I, Jurić SL, Gulić T, Lisnić B, Zagorac GB, Lučin HM, Lučin P
Biomedicines 2025 Apr 11;13(4)
Biomedicines 2025 Apr 11;13(4)
HIF-1α/m(6)A/NF-κB/CCL3 axis-mediated immunosurveillance participates in low level benzene-related erythrohematopoietic development toxicity.
Cong X, Li X, Xu K, Yin L, Liang G, Sun R, Pu Y, Zhang J
Environment international 2024 Feb;184:108493
Environment international 2024 Feb;184:108493
Sorting nexin 3 exacerbates doxorubicin-induced cardiomyopathy via regulation of TFRC-dependent ferroptosis.
Yu W, Hu Y, Liu Z, Guo K, Ma D, Peng M, Wang Y, Zhang J, Zhang X, Wang P, Zhang J, Liu P, Lu J
Acta pharmaceutica Sinica. B 2023 Dec;13(12):4875-4892
Acta pharmaceutica Sinica. B 2023 Dec;13(12):4875-4892
EGF-SNX3-EGFR axis drives tumor progression and metastasis in triple-negative breast cancers.
Cicek E, Circir A, Oyken M, Akbulut Caliskan O, Dioken DN, Guntekin Ergun S, Cetin-Atalay R, Sapmaz A, Ovaa H, Sahin O, Erson-Bensan AE
Oncogene 2022 Jan;41(2):220-232
Oncogene 2022 Jan;41(2):220-232
Sorting nexin 3 induces heart failure via promoting retromer-dependent nuclear trafficking of STAT3.
Lu J, Xu S, Huo Y, Sun D, Hu Y, Wang J, Zhang X, Wang P, Li Z, Liang M, Wu Z, Liu P
Cell death and differentiation 2021 Oct;28(10):2871-2887
Cell death and differentiation 2021 Oct;28(10):2871-2887
MON2 Guides Wntless Transport to the Golgi through Recycling Endosomes.
Zhao SB, Dean N, Gao XD, Fujita M
Cell structure and function 2020 Jun 13;45(1):77-92
Cell structure and function 2020 Jun 13;45(1):77-92
SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion.
McGough IJ, de Groot REA, Jellett AP, Betist MC, Varandas KC, Danson CM, Heesom KJ, Korswagen HC, Cullen PJ
Nature communications 2018 Sep 13;9(1):3737
Nature communications 2018 Sep 13;9(1):3737
Label-free proteomic analysis of placental proteins during Toxoplasma gondii infection.
Jiao F, Zhang D, Jiang M, Mi J, Liu X, Zhang H, Hu Z, Xu X, Hu X
Journal of proteomics 2017 Jan 6;150:31-39
Journal of proteomics 2017 Jan 6;150:31-39
Class III phosphatidylinositol-3-OH kinase controls epithelial integrity through endosomal LKB1 regulation.
O'Farrell F, Lobert VH, Sneeggen M, Jain A, Katheder NS, Wenzel EM, Schultz SW, Tan KW, Brech A, Stenmark H, Rusten TE
Nature cell biology 2017 Dec;19(12):1412-1423
Nature cell biology 2017 Dec;19(12):1412-1423
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The SNX3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SNX3. This antibody recognizes human,mouse,rat antigen. The SNX3 antibody has been validated for the following applications: ELISA, WB analysis.