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Learnorb67176
antibody from Biorbyt
Targeting: KDM2A
CXXC8, DKFZP434M1735, FBL11, FBL7, FBXL11, FLJ00115, JHDM1A, KIAA1004, LILINA
Western blotAntibody data
- Antibody Data
- Antigen structure
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- Product number
- orb67176 - Provider product page
- Provider
- Biorbyt
- Product name
- KDM2A antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal to KDM2A.Lysine-specific demethylase 2A (KDM2A) is a histone demethylase belonging to the JHDM1 histonedemethylase family. KDM2A specifically demethylates 'Lys-36' of histone H3, thereby playing acentral role in histone code. It preferentially demethylates dimethylated H3 'Lys-36' residue while ithas weak or no activity for mono-and tri-methylated H3 'Lys-36'. KDM2A is required to maintain theheterochromatic state. It associates with centromeres and represses transcription of small non-codingRNAs encoded by the clusters of satellite repeats at the centromere. KDM2A is required to sustaincentromeric integrity and genomic stability, particularly during mitosis.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Vial size
- 100 ul
- Storage
- -20°C
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