RA0296

antibody from Oursmab

Targeting: HTRA1 ARMD7, HtrA, IGFBP5-protease, PRSS11

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0296

Provider

Oursmab

Product name

Galegenimab (Biosimilar Reference Antibody) (HTRA1)

Antibody type

Monoclonal

Description

Galegenimab (development codes FHTR2163 and RO7171009) is an investigational biologic agent engineered as a fragment antigen-binding (Fab) derived from a humanized monoclonal antibody. It is designed for potential therapeutic applications where modulation of a specific extracellular protease is desired. Its unique Fab format, lacking the Fc region of a full antibody, is chosen to facilitate specific tissue penetration, reduce potential effector functions, and achieve a distinct pharmacokinetic profile. Galegenimab functions by specifically binding to and inhibiting the enzymatic activity of its target protein, HtrA1 (High-temperature requirement A serine peptidase 1), thereby aiming to modulate the proteolytic processes in which HtrA1 is involved.

Reactivity

Human

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.