Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 21728-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21728-1-AP, RRID:AB_10804773
- Product name
- IDE antibody
- Antibody type
- Polyclonal
- Description
- IDE antibody (Cat. #21728-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A novel pectin from Polygala tenuifolia blocks Aβ42 aggregation and production by enhancing insulin-degradation enzyme and neprilysin.
Ginsenoside compound K ameliorates Alzheimer's disease in HT22 cells by adjusting energy metabolism.
Ginsenoside Compound K Regulates Amyloid β via the Nrf2/Keap1 Signaling Pathway in Mice with Scopolamine Hydrobromide-Induced Memory Impairments.
OAB-14, a bexarotene derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice.
MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation.
Novel Serum Biomarkers Detected by Protein Array in Polycystic Ovary Syndrome with Low Progesterone Level.
Activation of α7 nicotinic acetylcholine receptor alleviates Aβ1-42-induced neurotoxicity via downregulation of p38 and JNK MAPK signaling pathways.
A pectin from fruits of Lycium barbarum L. decreases β-amyloid peptide production through modulating APP processing.
Effect of naringenin on brain insulin signaling and cognitive functions in ICV-STZ induced dementia model of rats.
Cell surface expression of the major amyloid-β peptide (Aβ)-degrading enzyme, neprilysin, depends on phosphorylation by mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK) and dephosphorylation by protein phosphatase 1a.
Zeng H, Li P, Zhou L, Ding K
International journal of biological macromolecules 2020 Oct 15;161:35-43
International journal of biological macromolecules 2020 Oct 15;161:35-43
Ginsenoside compound K ameliorates Alzheimer's disease in HT22 cells by adjusting energy metabolism.
Chen X, Li H, Yang Q, Lan X, Wang J, Cao Z, Shi X, Li J, Kan M, Qu X, Li N
Molecular biology reports 2019 Oct;46(5):5323-5332
Molecular biology reports 2019 Oct;46(5):5323-5332
Ginsenoside Compound K Regulates Amyloid β via the Nrf2/Keap1 Signaling Pathway in Mice with Scopolamine Hydrobromide-Induced Memory Impairments.
Yang Q, Lin J, Zhang H, Liu Y, Kan M, Xiu Z, Chen X, Lan X, Li X, Shi X, Li N, Qu X
Journal of molecular neuroscience : MN 2019 Jan;67(1):62-71
Journal of molecular neuroscience : MN 2019 Jan;67(1):62-71
OAB-14, a bexarotene derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice.
Yuan C, Guo X, Zhou Q, Du F, Jiang W, Zhou X, Liu P, Chi T, Ji X, Gao J, Chen C, Lang H, Xu J, Liu D, Yang Y, Qiu S, Tang X, Chen G, Zou L
Biochimica et biophysica acta. Molecular basis of disease 2019 Jan;1865(1):161-180
Biochimica et biophysica acta. Molecular basis of disease 2019 Jan;1865(1):161-180
MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation.
Zhu BL, Long Y, Luo W, Yan Z, Lai YJ, Zhao LG, Zhou WH, Wang YJ, Shen LL, Liu L, Deng XJ, Wang XF, Sun F, Chen GJ
Brain : a journal of neurology 2019 Jan 1;142(1):176-192
Brain : a journal of neurology 2019 Jan 1;142(1):176-192
Novel Serum Biomarkers Detected by Protein Array in Polycystic Ovary Syndrome with Low Progesterone Level.
Zheng Q, Zhou F, Cui X, Liu M, Li Y, Liu S, Tan J, Yan Q
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(6):2297-2310
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(6):2297-2310
Activation of α7 nicotinic acetylcholine receptor alleviates Aβ1-42-induced neurotoxicity via downregulation of p38 and JNK MAPK signaling pathways.
Chang KW, Zong HF, Ma KG, Zhai WY, Yang WN, Hu XD, Xu JH, Chen XL, Ji SF, Qian YH
Neurochemistry international 2018 Nov;120:238-250
Neurochemistry international 2018 Nov;120:238-250
A pectin from fruits of Lycium barbarum L. decreases β-amyloid peptide production through modulating APP processing.
Zhou L, Liao W, Zeng H, Yao Y, Chen X, Ding K
Carbohydrate polymers 2018 Dec 1;201:65-74
Carbohydrate polymers 2018 Dec 1;201:65-74
Effect of naringenin on brain insulin signaling and cognitive functions in ICV-STZ induced dementia model of rats.
Yang W, Ma J, Liu Z, Lu Y, Hu B, Yu H
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2014 May;35(5):741-51
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2014 May;35(5):741-51
Cell surface expression of the major amyloid-β peptide (Aβ)-degrading enzyme, neprilysin, depends on phosphorylation by mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK) and dephosphorylation by protein phosphatase 1a.
Kakiya N, Saito T, Nilsson P, Matsuba Y, Tsubuki S, Takei N, Nawa H, Saido TC
The Journal of biological chemistry 2012 Aug 24;287(35):29362-72
The Journal of biological chemistry 2012 Aug 24;287(35):29362-72
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 21728-1-AP(IDE antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 21728-1-AP(IDE antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The IDE antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human IDE. This antibody recognizes human, mouse, rat antigen. The IDE antibody has been validated for the following applications: ELISA, WB, IHC analysis.