Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- ABIN2847391 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Insulin-Degrading Enzyme (IDE) (AA 406-435), (Center) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 406-435, Center
- Antibody clone number
- RB12553
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Promoting scientific standards in Germany.
Complex formation between metabolic enzymes in tumor cells: unfolding the MDR1-IDE paradigm.
Insulin-degrading enzyme is genetically associated with Alzheimer's disease in the Finnish population.
Decreased catalytic activity of the insulin-degrading enzyme in chromosome 10-linked Alzheimer disease families.
Immunohistochemical demonstration of the zinc metalloprotease insulin-degrading enzyme in normal and malignant human breast: correlation with tissue insulin levels.
Insulin degrading enzyme is a cellular receptor mediating varicella-zoster virus infection and cell-to-cell spread.
Radulescu RT, Fischer K, Stange E, Schulze J
Science (New York, N.Y.) 2010 Apr 16;328(5976):307
Science (New York, N.Y.) 2010 Apr 16;328(5976):307
Complex formation between metabolic enzymes in tumor cells: unfolding the MDR1-IDE paradigm.
Radulescu RT, Poznic M, Pavelic K
Molecular cancer therapeutics 2009 Nov;8(11):3171
Molecular cancer therapeutics 2009 Nov;8(11):3171
Insulin-degrading enzyme is genetically associated with Alzheimer's disease in the Finnish population.
Vepsäläinen S, Parkinson M, Helisalmi S, Mannermaa A, Soininen H, Tanzi RE, Bertram L, Hiltunen M
Journal of medical genetics 2007 Sep;44(9):606-8
Journal of medical genetics 2007 Sep;44(9):606-8
Decreased catalytic activity of the insulin-degrading enzyme in chromosome 10-linked Alzheimer disease families.
Kim M, Hersh LB, Leissring MA, Ingelsson M, Matsui T, Farris W, Lu A, Hyman BT, Selkoe DJ, Bertram L, Tanzi RE
The Journal of biological chemistry 2007 Mar 16;282(11):7825-32
The Journal of biological chemistry 2007 Mar 16;282(11):7825-32
Immunohistochemical demonstration of the zinc metalloprotease insulin-degrading enzyme in normal and malignant human breast: correlation with tissue insulin levels.
Radulescu RT, Hufnagel C, Luppa P, Hellebrand H, Kuo WL, Rosner MR, Harbeck N, Giersig C, Meindl A, Schmitt M, Weirich G
International journal of oncology 2007 Jan;30(1):73-80
International journal of oncology 2007 Jan;30(1):73-80
Insulin degrading enzyme is a cellular receptor mediating varicella-zoster virus infection and cell-to-cell spread.
Li Q, Ali MA, Cohen JI
Cell 2006 Oct 20;127(2):305-16
Cell 2006 Oct 20;127(2):305-16
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Supportive validation
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- WB
- Submitted by
- antibodies-online (provider)
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- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC