Antibody data
- Antibody Data
- Antigen structure
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- Product number
- AMM02160G - Provider product page
- Provider
- Leading Biology
- Product name
- NOTCH4 Antibody (clone L5C5)
- Antibody type
- Monoclonal
- Description
- Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system (By similarity).
- Reactivity
- Human
- Host
- Mouse
- Antibody clone number
- L5C5
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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