Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- HPA036671 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA036671, RRID:AB_10602085
- Product name
- Anti-TRMT10C
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human TRMT10C, Gene description: tRNA methyltransferase 10 homolog C (S. cerevisiae), Alternative Gene Names: FLJ20432, MRPP1, RG9MTD1, Validated applications: ICC, IHC, WB, Uniprot ID: Q7L0Y3, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Post-transcriptional methylation of mitochondrial-tRNA differentially contributes to mitochondrial pathology
Cytosolic N6AMT1- dependent translation supports mitochondrial RNA processing
Concerted regulation of mitochondrial and nuclear non‐coding RNA s by a dual‐targeted RN ase Z
Adult-onset obesity is triggered by impaired mitochondrial gene expression
The Pseudouridine Synthase RPUSD4 Is an Essential Component of Mitochondrial RNA Granules
Estrogen-Mediated Regulation of Mitochondrial Gene Expression
Maharjan S, Gamper H, Yamaki Y, Christian T, Henley R, Li N, Suzuki T, Suzuki T, Piccirilli J, Wanunu M, Seifert E, Wallace D, Hou Y
Nature Communications 2024;15(1)
Nature Communications 2024;15(1)
Cytosolic N6AMT1- dependent translation supports mitochondrial RNA processing
Foged M, Recazens E, Chollet S, Lisci M, Allen G, Zinshteyn B, Boutguetait D, Münch C, Mootha V, Jourdain A
Proceedings of the National Academy of Sciences 2024;121(47)
Proceedings of the National Academy of Sciences 2024;121(47)
Concerted regulation of mitochondrial and nuclear non‐coding RNA s by a dual‐targeted RN ase Z
Siira S, Rossetti G, Richman T, Perks K, Ermer J, Kuznetsova I, Hughes L, Shearwood A, Viola H, Hool L, Rackham O, Filipovska A
EMBO reports 2018;19(10)
EMBO reports 2018;19(10)
Adult-onset obesity is triggered by impaired mitochondrial gene expression
Perks K, Ferreira N, Richman T, Ermer J, Kuznetsova I, Shearwood A, Lee R, Viola H, Johnstone V, Matthews V, Hool L, Rackham O, Filipovska A
Science Advances 2017;3(8)
Science Advances 2017;3(8)
The Pseudouridine Synthase RPUSD4 Is an Essential Component of Mitochondrial RNA Granules
Zaganelli S, Rebelo-Guiomar P, Maundrell K, Rozanska A, Pierredon S, Powell C, Jourdain A, Hulo N, Lightowlers R, Chrzanowska-Lightowlers Z, Minczuk M, Martinou J
Journal of Biological Chemistry 2017;292(11):4519-4532
Journal of Biological Chemistry 2017;292(11):4519-4532
Estrogen-Mediated Regulation of Mitochondrial Gene Expression
Lopez Sanchez M, Shearwood A, Chia T, Davies S, Rackham O, Filipovska A
Molecular Endocrinology 2015;29(1):14-27
Molecular Endocrinology 2015;29(1):14-27
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Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Genetic validation
- Main image
- Experimental details
- Western blot analysis in A-431 cells transfected with control siRNA, target specific siRNA probe #1, using Anti-TRMT10C antibody. Remaining relative intensity is presented. Loading control: Anti-PPIB.
- Sample type
- Human
- Protocol
- Protocol
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & mitochondria.
- Sample type
- Human