CABT-BL3584

antibody from Creative Diagnostics

Targeting: TIE1 JTK14, TIE

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

CABT-BL3584

Provider

Creative Diagnostics

Product name

Anti-TIE1 monoclonal antibody, clone 3D8

Antibody type

Monoclonal

Description

This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

3D8

Storage

Store at -2°C or lower. Aliquot to avoid repeated freezing and thawing.