26885-1-AP

antibody from Proteintech Group

Targeting: TRIM47 GOA, RNF100

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

26885-1-AP

Provider

Proteintech Group

Product name

TRIM47 antibody

Antibody type

Polyclonal

Description

TRIM47 antibody (Cat. #26885-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

E3 ubiquitin ligase TRIM47 promotes intrahepatic cholangiocarcinoma progression by ubiquitinating fumarate hydratase and modulating macrophage polarization.

Fu Y, Wu J, Shi J, Jia C
The Journal of biological chemistry 2026 Jan;302(1):111035

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Knockdown of TRIM47 Overcomes Paclitaxel Resistance in Ovarian Cancer by Suppressing the TGF-β Pathway via PPM1A.

Wang H, Chen S, Xu F, Chen X
American journal of reproductive immunology (New York, N.Y. : 1989) 2025 Jun;93(6):e70102

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TRIM47 is a prognostic biomarker for gallbladder cancer and promotes tumor progression through regulating K63-linked ubiquitination of PARP1.

Xu M, Deng C, Man Z, Zhu H
Translational oncology 2025 Jan;51:102164

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TRIM47 promotes head and neck squamous cell carcinoma malignant progression by degrading XAF1 through ubiquitination.

Yu C, Zhang C, Zhang Q, Zhang C, Han J, Li J
iScience 2025 Jan 17;28(1):111590

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TRIM47 promotes hypopharyngeal and laryngeal cancers progression through promoting K63-linked ubiquitination of vimentin.

Qin S, Chang F, Sun X, Li Z, Wang Y, Lei D
Cancer science 2025 Feb;116(2):367-380

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TRIM47-facilitated PLK1 stabilization promotes the proliferation of liver cancer cells.

Xie T, Fan X, Yu T, Zhu Q, Zhang Q, Li N, Wang T, Qian Y, Deng K, Xin H, Li Y, Huang X
Cellular oncology (Dordrecht, Netherlands) 2025 Dec 29;49(1):7

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Palmitoylation of TRIM47 Regulates ATG16L1-Mediated Autophagy to Exacerbate Respiratory Distress Syndrome in Sepsis.

Wang Q, Deng L, Cao Y, Yan S, Xing W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Dec 15;39(23):e71304

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TRIM47 Facilitates Osteosarcoma Progression via Destabilising FBP1 and Thus Activation of Wnt/β-Catenin Pathway.

Wang H, Chen X, Nie F, Zhong M, Fang Z, Qiu Z, Zhou L, Le Y, Wei X, Liao Y, Fang Z
Journal of cellular and molecular medicine 2025 Aug;29(15):e70753

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TRIM47 promotes trichloroethylene-induced immune kidney injury by degrading SIRT1 through ubiquitination.

Xie H, Zhou P, You C, Zhao J, Zhang J, Zhu Q
Toxicology research 2025 Aug;14(4):tfaf089

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GRK2 activates TRAF2-NF-κB signalling to promote hyperproliferation of fibroblast-like synoviocytes in rheumatoid arthritis.

Han C, Jiang L, Wang W, Zuo S, Gu J, Chen L, Chen Z, Kuai J, Yang X, Xu L, Ma Y, Wei W
Acta pharmaceutica Sinica. B 2025 Apr;15(4):1956-1973

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TRIM47 inhibits cisplatin chemosensitivity and endoplasmic reticulum stress-induced apoptosis of ovarian cancer cells.

Zhao J, Zhang J, Tong X, Zhao L, Cao R
Molecular and cellular probes 2024 Oct;77:101978

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Transcriptomic analysis reveals transcription factors implicated in radon-induced lung carcinogenesis.

Liu X, Peng Y, Chen R, Zhou Y, Zou X, Xia M, Wu X, Yu M
Toxicology research 2024 Oct;13(5):tfae161

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Arginine methylation-dependent TRIM47 stability mediated by CARM1 promotes the metastasis of hepatocellular carcinoma.

Tang Y, Meng X, Luo X, Yao W, Tian L, Zhang Z, Zhao Y, Xiao J, Zhu H, Hu J
Cell death discovery 2024 Nov 20;10(1):477

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TRIM47-CDO1 axis dictates hepatocellular carcinoma progression by modulating ferroptotic cell death through the ubiquitin‒proteasome system.

Zhang J, Yimamu M, Cheng Z, Ji J, Wu L, Feng J, Xu X, Wu J, Guo C
Free radical biology & medicine 2024 Jul;219:31-48

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Featured interactome of homocysteine-inducible endoplasmic reticulum protein uncovers novel binding partners in response to ER stress.

Su R, Yin J, Ruan X, Chen Y, Wan P, Luo Z
Computational and structural biotechnology journal 2023;21:4478-4487

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Knocking down Trim47 ameliorated sevoflurane-induced neuronal cell injury and cognitive impairment in rats.

Zhu Y, Zhang M, Wang J, Wang Q
Experimental brain research 2023 May;241(5):1437-1446

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TRIM47 promotes ovarian cancer cell proliferation, migration, and invasion by activating STAT3 signaling.

Wang X, Fu Y, Xing Y
Clinics (Sao Paulo, Brazil) 2022;77:100122

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TRIM47 promotes glioma angiogenesis by suppressing Smad4.

Wang Z, Li Z, Han C, Cheng Y, Wang K
In vitro cellular & developmental biology. Animal 2022 Oct;58(9):771-779

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TRIM47 is a novel endothelial activation factor that aggravates lipopolysaccharide-induced acute lung injury in mice via K63-linked ubiquitination of TRAF2.

Qian Y, Wang Z, Lin H, Lei T, Zhou Z, Huang W, Wu X, Zuo L, Wu J, Liu Y, Wang LF, Guan XH, Deng KY, Fu M, Xin HB
Signal transduction and targeted therapy 2022 May 6;7(1):148

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Trim47 overexpression correlates with poor prognosis in gastric cancer.

Xia Y, Wei Z, Huang W, Wei X, He Y
Neoplasma 2021 Mar;68(2):307-316